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Yvonne F. Heijdra - One of the best experts on this subject based on the ideXlab platform.
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overweight is an independent risk factor for reduced lung Volumes in myotonic dystrophy type 1
PLOS ONE, 2016Co-Authors: Charlotte Seijger, Gea Drost, Joram M. Posma, Baziel G. M. Van Engelen, Yvonne F. HeijdraAbstract:Background In this large observational study population of 105 myotonic dystrophy type 1 (DM1) patients, we investigate whether bodyweight is a contributor of total lung capacity (TLC) independent of the impaired inspiratory muscle strength. Methods Body composition was assessed using the combination of body mass index (BMI) and fat-free mass index. Pulmonary function tests and respiratory muscle strength measurements were performed on the same day. Patients were stratified into normal (BMI = 25 kg/m(2)) groups. Multiple linear regression was used to find significant contributors for TLC. Results Overweight was present in 59% of patients, and body composition was abnormal in almost all patients. In overweight patients, TLC was significantly (p = 2.40x10(-3)) decreased, compared with normal-weight patients, while inspiratory muscle strength was similar in both groups. The decrease in TLC in overweight patients was mainly due to a decrease in Expiratory Reserve Volume (ERV) further illustrated by a highly significant (p = 1.33x10(-10)) correlation between BMI and ERV. Multiple linear regression showed that TLC can be predicted using only BMI and the forced inspiratory Volume in 1 second, as these were the only significant contributors. Conclusions This study shows that, in DM1 patients, overweight further reduces lung Volumes, as does impaired inspiratory muscle strength. Additionally, body composition is abnormal in almost all DM1 patients.
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Stacked-bar histogram of total lung capacity (TLC) (% of predicted) in patients with normal weight (body mass index [BMI] < 25 kg/m2, n = 43) and overweight (BMI ≥ 25 kg/m2, n = 62), compared with their predicted values.
2016Co-Authors: Charlotte G. W. Seijger, Gea Drost, Joram M. Posma, Baziel G. M. Van Engelen, Yvonne F. HeijdraAbstract:The black section of the stacked-bar indicates the residual Volume (RV), the gray section the Expiratory Reserve Volume (ERV) and the white section the inspiratory capacity (IC). The RV and ERV combined (black plus grey) is the functional Reserve capacity (FRC). A restrictive pattern of pulmonary function is shown for both groups, and the TLC is further decreased in overweight compared with normal-weight patients, mainly due to the decreased ERV.
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Overweight Is an Independent Risk Factor for Reduced Lung Volumes in Myotonic Dystrophy Type 1
2016Co-Authors: Charlotte G. W. Seijger, Gea Drost, Joram M. Posma, Baziel G. M. Van Engelen, Yvonne F. HeijdraAbstract:BackgroundIn this large observational study population of 105 myotonic dystrophy type 1 (DM1) patients, we investigate whether bodyweight is a contributor of total lung capacity (TLC) independent of the impaired inspiratory muscle strength.MethodsBody composition was assessed using the combination of body mass index (BMI) and fat-free mass index. Pulmonary function tests and respiratory muscle strength measurements were performed on the same day. Patients were stratified into normal (BMI < 25 kg/m2) and overweight (BMI ≥ 25 kg/m2) groups. Multiple linear regression was used to find significant contributors for TLC.ResultsOverweight was present in 59% of patients, and body composition was abnormal in almost all patients. In overweight patients, TLC was significantly (p = 2.40×10−3) decreased, compared with normal-weight patients, while inspiratory muscle strength was similar in both groups. The decrease in TLC in overweight patients was mainly due to a decrease in Expiratory Reserve Volume (ERV) further illustrated by a highly significant (p = 1.33×10−10) correlation between BMI and ERV. Multiple linear regression showed that TLC can be predicted using only BMI and the forced inspiratory Volume in 1 second, as these were the only significant contributors.ConclusionsThis study shows that, in DM1 patients, overweight further reduces lung Volumes, as does impaired inspiratory muscle strength. Additionally, body composition is abnormal in almost all DM1 patients.
Endang Kumaidah - One of the best experts on this subject based on the ideXlab platform.
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perbedaan nilai total lung capacity peak Expiratory flow dan Expiratory Reserve Volume antar cabang olahraga pada atlet usia 6 12 tahun
Journal of Medical and Environmental Sciences, 2016Co-Authors: Radyoko Heru Rahbanu, Yuswo Supatmo, Endang KumaidahAbstract:Background: The development of a person's lungs are the most rapidly while still a child. Activity plays an important role in lung development. Research shows that exercise a positive impact on the development of lung and cardiovascular function. Each type of sport has a different energy system depends on the type of training Objective: To prove the difference in value of TLC, PEF and ERV among sports in athletes aged 6-12 years. Methods: This study used a descriptive analytic study is not paired with the cross-sectional design. Samples were 20 male athletes 6-12 years in the sport Volleyball, Soccer, Swimming and Taekwondo. Data retrieval characteristics such as age, height, weight, chest circumference and BMI. TLC values, PEF and ERV is measured by using a spirometer Spirolab II. Statistical test using Kruskal Wallis test. Results: The mean value of the group TLC Volleyball athletes was 2.21 L, athletes Football is 3.4 L, athletes Pool was 3.68 L and Taekwondo athletes was 3.19 L. The mean value of PEF group of athletes Volleyball is 4, 45 L / min, athletes Football is 3.8 L / min, athletes Pool was 4.44 L / min and Taekwondo athletes was 4.09 L / min. The mean value of ERV group of athletes was 0.75 L Volleyball, athletes Football is 0.53 L, 0.54 L Swimming athletes and athletes Taekwondo 0.49 L. Conclusion: In this study, there were significant differences between the average value of TLC sport athletes 6-12 years of age. Meanwhile, there was no significant difference in the average value of PEF and ERV sports athletes aged between 6-12 years.
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perbedaan nilai total lung capacity peak Expiratory flow dan Expiratory Reserve Volume antar cabang olahraga pada atlet usia 6 12 tahun studi pada cabang olahraga bola voli sepak bola renang dan taekwondo kota semarang
2015Co-Authors: Radyoko Heru Rahbanu, Yuswo Supatmo, Endang KumaidahAbstract:Background: The development of a person's lungs are the most rapidly while still a child. Activity plays an important role in lung development. Research shows that exercise a positive impact on the development of lung and cardiovascular function.Each type of sport has a different energy system depends on the type of training Objective: To prove the difference in value of TLC, PEF and ERV among sports in athletes aged 6-12 years Methods: This study used a descriptive analytic study is Not paired with the crosssectional design. Samples were 20 male 6-12 years athletes in the sport Volleyball,Soccer,Swimming and Taekwondo. Data retrieval characteristics such as age,height, weight, chest circumference and BMI. TLC values, PEF and ERV is measured by using a spirometer Spirolab II. Statistical test using Kruskal Wallis test. Results: The mean value of the group TLC Volleyball athletes was 2.21 L, athletes Football is 3.4 L, athletes Pool was 3.68 L and Taekwondo athletes was 3.19 L. The mean value of PEF group of athletes Volleyball is 4, 45 L / min, athletes Football is 3.8 L / min, athletes Pool was 4.44 L / min and Taekwondo athletes was 4.09 L / min. The mean value of ERV group of athletes was 0.75 L Volleyball, athletes Football is 0.53 L, 0.54 L Swimming athletes and athletes Taekwondo 0.49 L. Conclusion: In this study, there were significant differences between the average value of TLC sport athletes 6-12 years of age. Meanwhile, there was no significant difference in the average value of PEF and ERV sports athletes aged between 6-12 years. Keywords: athlete, total lung capacity, peak Expiratory flow, ecpiratory Reserve Volume, TLC, PEF, ER
Simone Dal Corso - One of the best experts on this subject based on the ideXlab platform.
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Expiratory Reserve Volume during slow expiration with glottis opened in infralateral decubitus position eltgol in chronic pulmonary disease technique description and reproducibility
Respiratory Care, 2015Co-Authors: Fernanda De Cordoba Lanza, Anderson Alves De Camargo, Cintia Santos Alves, Roberta Loures Dos Santos, Simone Dal CorsoAbstract:BACKGROUND: There has not been a detailed description of Expiratory Reserve Volume (ERV) during slow expiration with glottis open in infralateral decubitus position (ELTGOL, for Expiration Lente Totale Glotte Ouverte en infraLateral) and its reproducibility. The aim of this study was to determine ERV during ELTGOL and to evaluate ERV intra-observer and inter-observer reliability. METHODS: In this prospective study, subjects were 30–70 y of age with chronic lung disease. ELTGOL (an active-passive or active physiotherapy technique) was applied in random order by 3 observers: 2 trained physiotherapists (PT 1 and PT 2) and the subject him/herself. Two ELTGOL compressions (A and B) were applied by PT 1, PT 2, and the subject. RESULTS: Thirty-two subjects were evaluated with moderate lung obstruction, FEV1: 47.7 ± 15.4, and ERV: 61.7 ± 29.4. The mean value of ERV for PT 1 was 51.4 ± 24.8%; for PT 2, it was 54.3 ± 31.8%; and for the subject, it was 53.5 ± 26.2% (P = .49). Considering the mean value of ERV, the ELTGOL mobilized more than 80% of ERV. There was good reliability intra-PT: PT 1, intraclass correlation coefficient (ICC) 0.85 (0.70–0.93), P CONCLUSIONS: ELTGOL mobilized more than 80% of ERV in subjects with moderate airway obstruction; there is no difference in ERV exhaled during the technique applied by a physiotherapist or by the subject. ELTGOL is a reproducible technique, determined by inter- and intra-observer testing.
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Expiratory Reserve Volume during slow expiration with glottis opened in infralateral decubitus position eltgol in chronic pulmonary disease technique description and reproducibility
Respiratory Care, 2015Co-Authors: Fernanda De Cordoba Lanza, Anderson Alves De Camargo, Cintia Santos Alves, Roberta Loures Dos Santos, Simone Dal CorsoAbstract:BACKGROUND: There has not been a detailed description of Expiratory Reserve Volume (ERV) during slow expiration with glottis open in infralateral decubitus position (ELTGOL, for Expiration Lente Totale Glotte Ouverte en infraLateral) and its reproducibility. The aim of this study was to determine ERV during ELTGOL and to evaluate ERV intra-observer and inter-observer reliability. METHODS: In this prospective study, subjects were 30–70 y of age with chronic lung disease. ELTGOL (an active-passive or active physiotherapy technique) was applied in random order by 3 observers: 2 trained physiotherapists (PT 1 and PT 2) and the subject him/herself. Two ELTGOL compressions (A and B) were applied by PT 1, PT 2, and the subject. RESULTS: Thirty-two subjects were evaluated with moderate lung obstruction, FEV1: 47.7 ± 15.4, and ERV: 61.7 ± 29.4. The mean value of ERV for PT 1 was 51.4 ± 24.8%; for PT 2, it was 54.3 ± 31.8%; and for the subject, it was 53.5 ± 26.2% (P = .49). Considering the mean value of ERV, the ELTGOL mobilized more than 80% of ERV. There was good reliability intra-PT: PT 1, intraclass correlation coefficient (ICC) 0.85 (0.70–0.93), P CONCLUSIONS: ELTGOL mobilized more than 80% of ERV in subjects with moderate airway obstruction; there is no difference in ERV exhaled during the technique applied by a physiotherapist or by the subject. ELTGOL is a reproducible technique, determined by inter- and intra-observer testing.
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chest wall mobility is related to respiratory muscle strength and lung Volumes in healthy subjects
Respiratory Care, 2013Co-Authors: Fernanda De Cordoba Lanza, Anderson Alves De Camargo, Lilian Rocha Ferraz Archija, Jessyca Pachi Rodrigues Selman, Carla Malaguti, Simone Dal CorsoAbstract:BACKGROUND: Chest wall mobility is often measured in clinical practice, but the correlations between chest wall mobility and respiratory muscle strength and lung Volumes are unknown. We investigate the associations between chest wall mobility, axillary and thoracic cirtometry values, respiratory muscle strength (maximum inspiratory pressure and maximum Expiratory pressure), and lung Volumes (Expiratory Reserve Volume, FEV 1, inspiratory capacity, FEV1/FVC), and the determinants of chest mobility in healthy subjects. METHODS: In 64 healthy subjects we measured inspiratory capacity, FVC, FEV 1, Expiratory Reserve Volume, maximum inspiratory pressure, and maximum Expiratory pressure, and chest wall mobility via axillary and thoracic cirtometry. We used linear regression to evaluate the influence of the measured variables on chest wall mobility. RESULTS: The subjects’ meanSD values were: age 243 years, axillary cirtometry 6.32.0 cm, thoracic cirtometry 7.5 2.3 cm; maximum inspiratory pressure 90.4 10.6% of predicted, maximum Expiratory pressure 92.8 13.5% of predicted, inspiratory capacity 99.7 8.6% of predicted, FVC 101.9 10.6% of predicted, FEV 1 98.2 10.3% of predicted, Expiratory Reserve Volume 90.9 19.9% of predicted. There were significant correlations between axillary cirtometry and FVC (r 0.32), FEV 1 (r 0.30), maximum inspiratory pressure (r 0.48), maximum Expiratory pressure (r 0.25), and inspiratory capacity (r 0.24), and between thoracic cirtometry and FVC (r 0.50), FEV 1 (r 0.48), maximum inspiratory pressure (r 0.46), maximum Expiratory pressure (r 0.37), inspiratory capacity (r 0.39), and Expiratory Reserve Volume (r 0.47). In multiple regression analysis the variable that best explained the axillary cirtometry variation was maximum inspiratory pressure (R 2 0.23), and for thoracic cirtometry it was FVC and maximum inspiratory pressure (R 2 0.32). CONCLUSIONS: Chest mobility in healthy subjects is
Fernanda De Cordoba Lanza - One of the best experts on this subject based on the ideXlab platform.
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Expiratory Reserve Volume during slow expiration with glottis opened in infralateral decubitus position eltgol in chronic pulmonary disease technique description and reproducibility
Respiratory Care, 2015Co-Authors: Fernanda De Cordoba Lanza, Anderson Alves De Camargo, Cintia Santos Alves, Roberta Loures Dos Santos, Simone Dal CorsoAbstract:BACKGROUND: There has not been a detailed description of Expiratory Reserve Volume (ERV) during slow expiration with glottis open in infralateral decubitus position (ELTGOL, for Expiration Lente Totale Glotte Ouverte en infraLateral) and its reproducibility. The aim of this study was to determine ERV during ELTGOL and to evaluate ERV intra-observer and inter-observer reliability. METHODS: In this prospective study, subjects were 30–70 y of age with chronic lung disease. ELTGOL (an active-passive or active physiotherapy technique) was applied in random order by 3 observers: 2 trained physiotherapists (PT 1 and PT 2) and the subject him/herself. Two ELTGOL compressions (A and B) were applied by PT 1, PT 2, and the subject. RESULTS: Thirty-two subjects were evaluated with moderate lung obstruction, FEV1: 47.7 ± 15.4, and ERV: 61.7 ± 29.4. The mean value of ERV for PT 1 was 51.4 ± 24.8%; for PT 2, it was 54.3 ± 31.8%; and for the subject, it was 53.5 ± 26.2% (P = .49). Considering the mean value of ERV, the ELTGOL mobilized more than 80% of ERV. There was good reliability intra-PT: PT 1, intraclass correlation coefficient (ICC) 0.85 (0.70–0.93), P CONCLUSIONS: ELTGOL mobilized more than 80% of ERV in subjects with moderate airway obstruction; there is no difference in ERV exhaled during the technique applied by a physiotherapist or by the subject. ELTGOL is a reproducible technique, determined by inter- and intra-observer testing.
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Expiratory Reserve Volume during slow expiration with glottis opened in infralateral decubitus position eltgol in chronic pulmonary disease technique description and reproducibility
Respiratory Care, 2015Co-Authors: Fernanda De Cordoba Lanza, Anderson Alves De Camargo, Cintia Santos Alves, Roberta Loures Dos Santos, Simone Dal CorsoAbstract:BACKGROUND: There has not been a detailed description of Expiratory Reserve Volume (ERV) during slow expiration with glottis open in infralateral decubitus position (ELTGOL, for Expiration Lente Totale Glotte Ouverte en infraLateral) and its reproducibility. The aim of this study was to determine ERV during ELTGOL and to evaluate ERV intra-observer and inter-observer reliability. METHODS: In this prospective study, subjects were 30–70 y of age with chronic lung disease. ELTGOL (an active-passive or active physiotherapy technique) was applied in random order by 3 observers: 2 trained physiotherapists (PT 1 and PT 2) and the subject him/herself. Two ELTGOL compressions (A and B) were applied by PT 1, PT 2, and the subject. RESULTS: Thirty-two subjects were evaluated with moderate lung obstruction, FEV1: 47.7 ± 15.4, and ERV: 61.7 ± 29.4. The mean value of ERV for PT 1 was 51.4 ± 24.8%; for PT 2, it was 54.3 ± 31.8%; and for the subject, it was 53.5 ± 26.2% (P = .49). Considering the mean value of ERV, the ELTGOL mobilized more than 80% of ERV. There was good reliability intra-PT: PT 1, intraclass correlation coefficient (ICC) 0.85 (0.70–0.93), P CONCLUSIONS: ELTGOL mobilized more than 80% of ERV in subjects with moderate airway obstruction; there is no difference in ERV exhaled during the technique applied by a physiotherapist or by the subject. ELTGOL is a reproducible technique, determined by inter- and intra-observer testing.
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chest wall mobility is related to respiratory muscle strength and lung Volumes in healthy subjects
Respiratory Care, 2013Co-Authors: Fernanda De Cordoba Lanza, Anderson Alves De Camargo, Lilian Rocha Ferraz Archija, Jessyca Pachi Rodrigues Selman, Carla Malaguti, Simone Dal CorsoAbstract:BACKGROUND: Chest wall mobility is often measured in clinical practice, but the correlations between chest wall mobility and respiratory muscle strength and lung Volumes are unknown. We investigate the associations between chest wall mobility, axillary and thoracic cirtometry values, respiratory muscle strength (maximum inspiratory pressure and maximum Expiratory pressure), and lung Volumes (Expiratory Reserve Volume, FEV 1, inspiratory capacity, FEV1/FVC), and the determinants of chest mobility in healthy subjects. METHODS: In 64 healthy subjects we measured inspiratory capacity, FVC, FEV 1, Expiratory Reserve Volume, maximum inspiratory pressure, and maximum Expiratory pressure, and chest wall mobility via axillary and thoracic cirtometry. We used linear regression to evaluate the influence of the measured variables on chest wall mobility. RESULTS: The subjects’ meanSD values were: age 243 years, axillary cirtometry 6.32.0 cm, thoracic cirtometry 7.5 2.3 cm; maximum inspiratory pressure 90.4 10.6% of predicted, maximum Expiratory pressure 92.8 13.5% of predicted, inspiratory capacity 99.7 8.6% of predicted, FVC 101.9 10.6% of predicted, FEV 1 98.2 10.3% of predicted, Expiratory Reserve Volume 90.9 19.9% of predicted. There were significant correlations between axillary cirtometry and FVC (r 0.32), FEV 1 (r 0.30), maximum inspiratory pressure (r 0.48), maximum Expiratory pressure (r 0.25), and inspiratory capacity (r 0.24), and between thoracic cirtometry and FVC (r 0.50), FEV 1 (r 0.48), maximum inspiratory pressure (r 0.46), maximum Expiratory pressure (r 0.37), inspiratory capacity (r 0.39), and Expiratory Reserve Volume (r 0.47). In multiple regression analysis the variable that best explained the axillary cirtometry variation was maximum inspiratory pressure (R 2 0.23), and for thoracic cirtometry it was FVC and maximum inspiratory pressure (R 2 0.32). CONCLUSIONS: Chest mobility in healthy subjects is
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prolonged slow expiration technique in infants effects on tidal Volume peak Expiratory flow and Expiratory Reserve Volume
Respiratory Care, 2011Co-Authors: Fernanda De Cordoba Lanza, Gustavo F Wandalsen, Ana Caroline Dela Bianca, Carolina Lopes Da Cruz, Guy Postiaux, Dirceu SoleAbstract:BACKGROUND: Prolonged slow expiration (PSE) is a physiotherapy technique often applied in infants to reduce pulmonary obstruction and clear secretions, but there have been few studies of PSE’s effects on the respiratory system. OBJECTIVE: To describe PSE’s effects on respiratory mechanics in infants. METHODS: We conducted a cross-sectional study with 18 infants who had histories of recurrent wheezing. The infants were sedated for lung-function testing, which was followed by PSE. The PSE consisted of 3 sequences of prolonged manual thoraco-abdominal compressions during the Expiratory phase. We measured peak Expiratory flow (PEF), tidal Volume (V T), and the frequency of sighs during and immediately after PSE. We described the exhaled Volume during PSE as a fraction of Expiratory Reserve Volume (%ERV). We quantified ERV with the raised-Volume rapid-thoracic-compression technique. RESULTS: The cohort’s mean age was 32.2 weeks, and they had an average of 4.8 previous wheezing episodes. During PSE there was significant V T reduction (80 17 mL vs 49 11 mL, P < .001), no significant change in PEF (149 32 mL/s vs 150 32 mL/s, P .54), and more frequent sighs (40% vs 5%, P .03), compared to immediately after PSE. The exhaled Volume increased in each PSE sequence (32 18% of ERV, 41 24% of ERV, and 53 20% of ERV, P .03). CONCLUSIONS: It was possible to confirm and quantify that PSE deflates the lung to ERV. PSE caused no changes in PEF, induced sigh breaths, and decreased V T, which is probably the main mechanical feature for mucus clear
Norbert Berend - One of the best experts on this subject based on the ideXlab platform.
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physiology of obesity and effects on lung function
Journal of Applied Physiology, 2010Co-Authors: Cheryl M Salome, Gregory G King, Norbert BerendAbstract:In obese people, the presence of adipose tissue around the rib cage and abdomen and in the visceral cavity loads the chest wall and reduces functional residual capacity (FRC). The reduction in FRC and in Expiratory Reserve Volume is detectable, even at a modest increase in weight. However, obesity has little direct effect on airway caliber. Spirometric variables decrease in proportion to lung Volumes, but are rarely below the normal range, even in the extremely obese, while reductions in Expiratory flows and increases in airway resistance are largely normalized by adjusting for lung Volumes. Nevertheless, the reduction in FRC has consequences for other aspects of lung function. A low FRC increases the risk of both Expiratory flow limitation and airway closure. Marked reductions in Expiratory Reserve Volume may lead to abnormalities in ventilation distribution, with closure of airways in the dependent zones of the lung and ventilation perfusion inequalities. Greater airway closure during tidal breathing is associated with lower arterial oxygen saturation in some subjects, even though lung CO-diffusing capacity is normal or increased in the obese. Bronchoconstriction has the potential to enhance the effects of obesity on airway closure and thus on ventilation distribution. Thus obesity has effects on lung function that can reduce respiratory well-being, even in the absence of specific respiratory disease, and may also exaggerate the effects of existing airway disease.
