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Yipeng He - One of the best experts on this subject based on the ideXlab platform.

  • traditional tibetan medicine induced high methylmercury Exposure Level and environmental mercury burden in tibet china
    Environmental Science & Technology, 2018
    Co-Authors: Shidong Ge, Menghan Cheng, Robert P. Mason, Zofia Baumann, Chenghao Yu, Yipeng He, Huizhong Shen, Long Chen, Qianggong Zhang
    Abstract:

    Highly elevated concentrations of total mercury (THg) and methylmercury (MeHg) were found in the municipal sewage in Tibet. Material flow analysis supports the hypothesis that these elevated concentrations are related to regular ingestion of Hg-containing Traditional Tibetan Medicine (TTM). In Tibet in 2015, a total of 3600 kg of THg was released from human body into the terrestrial environment as a result of TTM ingestion, amounting to 45% of the total THg release into the terrestrial environment in Tibet, hence substantially enhancing the environmental Hg burden. Regular ingestion of TTM leads to chronic Exposure of Tibetans to inorganic Hg (IHg) and MeHg, which is 34 to 3000-fold and 0–12-fold higher than from any other known dietary sources, respectively. Application of a human physiology model demonstrated that ingestion of TTM can induce high blood IHg and MeHg Levels in the human body. Moreover, 180 days would be required for the MeHg to be cleared out of the human body and return to the initial co...

  • Comment on ``Traditional Tibetan Medicine Induced High Methylmercury Exposure Level and Environmental Mercury Burden in Tibet, China''
    Environmental Science & Technology, 2018
    Co-Authors: Yipeng He, Shidong Ge, Menghan Cheng, Robert P. Mason, Zofia Baumann, Chenghao Yu, Huizhong Shen, Long Chen
    Abstract:

    Highly elevated concentrations of total mercury (THg) and methylmercury (MeHg) were found in the municipal sewage in Tibet. Material flow analysis supports the hypothesis that these elevated concentrations are related to regular ingestion of Hg-containing Traditional Tibetan Medicine (TTM). In Tibet in 2015, a total of 3600 kg of THg was released from human body into the terrestrial environment as a result of TTM ingestion, amounting to 45% of the total THg release into the terrestrial environment in Tibet, hence substantially enhancing the environmental Hg burden. Regular ingestion of TTM leads to chronic Exposure of Tibetans to inorganic Hg (IHg) and MeHg, which is 34 to 3000-fold and 0–12-fold higher than from any other known dietary sources, respectively. Application of a human physiology model demonstrated that ingestion of TTM can induce high blood IHg and MeHg Levels in the human body. Moreover, 180 days would be required for the MeHg to be cleared out of the human body and return to the initial co...

  • Traditional Tibetan Medicine Induced High Methylmercury Exposure Level and Environmental Mercury Burden in Tibet, China.
    Environmental science & technology, 2018
    Co-Authors: Yipeng He, Shidong Ge, Menghan Cheng, Robert P. Mason, Zofia Baumann, Chenghao Yu, Huizhong Shen, Long Chen
    Abstract:

    Highly elevated concentrations of total mercury (THg) and methylmercury (MeHg) were found in the municipal sewage in Tibet. Material flow analysis supports the hypothesis that these elevated concentrations are related to regular ingestion of Hg-containing Traditional Tibetan Medicine (TTM). In Tibet in 2015, a total of 3600 kg of THg was released from human body into the terrestrial environment as a result of TTM ingestion, amounting to 45% of the total THg release into the terrestrial environment in Tibet, hence substantially enhancing the environmental Hg burden. Regular ingestion of TTM leads to chronic Exposure of Tibetans to inorganic Hg (IHg) and MeHg, which is 34 to 3000-fold and 0-12-fold higher than from any other known dietary sources, respectively. Application of a human physiology model demonstrated that ingestion of TTM can induce high blood IHg and MeHg Levels in the human body. Moreover, 180 days would be required for the MeHg to be cleared out of the human body and return to the initial concentration i.e. prior to the ingestion of 1 TTM pill. Our analysis suggests that high Hg Level contained in TTM could be harmful to human health and elevate the environmental Hg burden in Tibet.

Long Chen - One of the best experts on this subject based on the ideXlab platform.

  • traditional tibetan medicine induced high methylmercury Exposure Level and environmental mercury burden in tibet china
    Environmental Science & Technology, 2018
    Co-Authors: Shidong Ge, Menghan Cheng, Robert P. Mason, Zofia Baumann, Chenghao Yu, Yipeng He, Huizhong Shen, Long Chen, Qianggong Zhang
    Abstract:

    Highly elevated concentrations of total mercury (THg) and methylmercury (MeHg) were found in the municipal sewage in Tibet. Material flow analysis supports the hypothesis that these elevated concentrations are related to regular ingestion of Hg-containing Traditional Tibetan Medicine (TTM). In Tibet in 2015, a total of 3600 kg of THg was released from human body into the terrestrial environment as a result of TTM ingestion, amounting to 45% of the total THg release into the terrestrial environment in Tibet, hence substantially enhancing the environmental Hg burden. Regular ingestion of TTM leads to chronic Exposure of Tibetans to inorganic Hg (IHg) and MeHg, which is 34 to 3000-fold and 0–12-fold higher than from any other known dietary sources, respectively. Application of a human physiology model demonstrated that ingestion of TTM can induce high blood IHg and MeHg Levels in the human body. Moreover, 180 days would be required for the MeHg to be cleared out of the human body and return to the initial co...

  • Comment on ``Traditional Tibetan Medicine Induced High Methylmercury Exposure Level and Environmental Mercury Burden in Tibet, China''
    Environmental Science & Technology, 2018
    Co-Authors: Yipeng He, Shidong Ge, Menghan Cheng, Robert P. Mason, Zofia Baumann, Chenghao Yu, Huizhong Shen, Long Chen
    Abstract:

    Highly elevated concentrations of total mercury (THg) and methylmercury (MeHg) were found in the municipal sewage in Tibet. Material flow analysis supports the hypothesis that these elevated concentrations are related to regular ingestion of Hg-containing Traditional Tibetan Medicine (TTM). In Tibet in 2015, a total of 3600 kg of THg was released from human body into the terrestrial environment as a result of TTM ingestion, amounting to 45% of the total THg release into the terrestrial environment in Tibet, hence substantially enhancing the environmental Hg burden. Regular ingestion of TTM leads to chronic Exposure of Tibetans to inorganic Hg (IHg) and MeHg, which is 34 to 3000-fold and 0–12-fold higher than from any other known dietary sources, respectively. Application of a human physiology model demonstrated that ingestion of TTM can induce high blood IHg and MeHg Levels in the human body. Moreover, 180 days would be required for the MeHg to be cleared out of the human body and return to the initial co...

  • Traditional Tibetan Medicine Induced High Methylmercury Exposure Level and Environmental Mercury Burden in Tibet, China.
    Environmental science & technology, 2018
    Co-Authors: Yipeng He, Shidong Ge, Menghan Cheng, Robert P. Mason, Zofia Baumann, Chenghao Yu, Huizhong Shen, Long Chen
    Abstract:

    Highly elevated concentrations of total mercury (THg) and methylmercury (MeHg) were found in the municipal sewage in Tibet. Material flow analysis supports the hypothesis that these elevated concentrations are related to regular ingestion of Hg-containing Traditional Tibetan Medicine (TTM). In Tibet in 2015, a total of 3600 kg of THg was released from human body into the terrestrial environment as a result of TTM ingestion, amounting to 45% of the total THg release into the terrestrial environment in Tibet, hence substantially enhancing the environmental Hg burden. Regular ingestion of TTM leads to chronic Exposure of Tibetans to inorganic Hg (IHg) and MeHg, which is 34 to 3000-fold and 0-12-fold higher than from any other known dietary sources, respectively. Application of a human physiology model demonstrated that ingestion of TTM can induce high blood IHg and MeHg Levels in the human body. Moreover, 180 days would be required for the MeHg to be cleared out of the human body and return to the initial concentration i.e. prior to the ingestion of 1 TTM pill. Our analysis suggests that high Hg Level contained in TTM could be harmful to human health and elevate the environmental Hg burden in Tibet.

Teresa Wronskanofer - One of the best experts on this subject based on the ideXlab platform.

  • occupational Exposure to nitrous oxide the role of scavenging and ventilation systems in reducing the Exposure Level in operating rooms
    International Journal of Hygiene and Environmental Health, 2007
    Co-Authors: Wojciech Krajewski, M Kucharska, Wiktor Wesolowski, Jan Stetkiewicz, Teresa Wronskanofer
    Abstract:

    Abstract Objectives The aim of this study was to assess the Level of occupational Exposure to nitrous oxide (N 2 O) in operating rooms (ORs), as related to different ventilation and scavenging systems used to remove waste anaesthetic gases from the work environment. Methods The monitoring of N 2 O in the air covered 35 ORs in 10 hospitals equipped with different systems for ventilation and anaesthetic scavenging. The examined systems included: natural ventilation with supplementary fresh air provided by a pressure ventilation system (up to 6 air changes/h); pressure and exhaust ventilation systems equipped with ventilation units supplying fresh air to and discharging contaminated air outside the working area (more than 10 air changes/h); complete air-conditioning system with laminar air flow (more than 15 air changes/h). The measurements were carried out during surgical procedures (general anaesthesia induced intravenously and maintained with inhaled N 2 O and sevofluran delivered through cuffed endotracheal tubes) with connected or disconnected air scavenging. Air was collected from the breathing zone of operating personnel continuously through the whole time of anaesthesia to Tedlar ® bags, and N 2 O concentrations in air samples were analyzed by adsorption gas chromatography/mass spectrometry. Results N 2 O Levels in excess of the occupational Exposure limit (OEL) value of 180 mg/m 3 were registered in all ORs equipped with ventilation systems alone. The OEL value was exceeded several times in rooms with natural ventilation plus supplementary pressure ventilations and twice or less in those with pressure/exhaust ventilation systems or air conditioning. N 2 O Levels below or within the OEL value were observed in rooms where the system of air conditioning or pressure/exhaust ventilation was combined with scavenging systems. Systems combining natural/pressure ventilation with scavenging were inadequate to maintain N 2 O concentration below the OEL value. Conclusion Air conditioning and an efficient pressure/exhaust ventilation (above 12 air exchanges/h) together with efficient active scavenging systems are sufficient to sustain N 2 O Exposure in ORs at Levels below or within the OEL value of 180 mg/m 3 .

Chungmin Liao - One of the best experts on this subject based on the ideXlab platform.

  • health risk assessment on human exposed to environmental polycyclic aromatic hydrocarbons pollution sources
    Science of The Total Environment, 2006
    Co-Authors: Szuchich Chen, Chungmin Liao
    Abstract:

    To assess how the human Exposure to environmental carcinogenic polycyclic aromatic hydrocarbons (PAHs) pollution sources generated from industrial, traffic and rural settings, we present a probabilistic risk model, appraised with reported empirical data. A probabilistic risk assessment framework is integrated with the potency equivalence factors (PEFs), age group-specific occupancy probability and the incremental lifetime cancer risk (ILCR) approaches to quantitatively estimate the Exposure risk for three age groups of adults, children, and infants. The benzo[a]pyrene equivalents based PAH concentrations in rural, traffic, and industrial areas associated with age group-specific occupancy probability at different environmental settings are used to calculate daily Exposure Level through inhalation and dermal contact pathways. Risk analysis indicates that the inhalation-ILCR and dermal contact-ILCR values for adults follow a lognormal distribution with geometric mean 1.04 � 10 � 4 and 3.85 � 10 � 5 and geometric standard deviation 2.10 and 2.75, respectively, indicating high potential cancer risk; whereas for the infants the risk values are less than 10 � 6 , indicating no significant cancer risk. Sensitivity analysis indicates that the input variables of cancer slope factor and daily inhalation Exposure Level have the greater impact than that of body weight on the inhalation-ILCR; whereas for the dermalILCR, particle-bound PAH-to-skin adherence factor and daily dermal Exposure Level have the significant influence than that of body weight. D 2005 Elsevier B.V. All rights reserved.

  • health risk assessment on human exposed to environmental polycyclic aromatic hydrocarbons pollution sources
    Science of The Total Environment, 2006
    Co-Authors: Szuchich Chen, Chungmin Liao
    Abstract:

    To assess how the human Exposure to environmental carcinogenic polycyclic aromatic hydrocarbons (PAHs) pollution sources generated from industrial, traffic and rural settings, we present a probabilistic risk model, appraised with reported empirical data. A probabilistic risk assessment framework is integrated with the potency equivalence factors (PEFs), age group-specific occupancy probability and the incremental lifetime cancer risk (ILCR) approaches to quantitatively estimate the Exposure risk for three age groups of adults, children, and infants. The benzo[a]pyrene equivalents based PAH concentrations in rural, traffic, and industrial areas associated with age group-specific occupancy probability at different environmental settings are used to calculate daily Exposure Level through inhalation and dermal contact pathways. Risk analysis indicates that the inhalation-ILCR and dermal contact-ILCR values for adults follow a lognormal distribution with geometric mean 1.04 � 10 � 4 and 3.85 � 10 � 5 and geometric standard deviation 2.10 and 2.75, respectively, indicating high potential cancer risk; whereas for the infants the risk values are less than 10 � 6 , indicating no significant cancer risk. Sensitivity analysis indicates that the input variables of cancer slope factor and daily inhalation Exposure Level have the greater impact than that of body weight on the inhalation-ILCR; whereas for the dermalILCR, particle-bound PAH-to-skin adherence factor and daily dermal Exposure Level have the significant influence than that of body weight. D 2005 Elsevier B.V. All rights reserved.

Zofia Baumann - One of the best experts on this subject based on the ideXlab platform.

  • traditional tibetan medicine induced high methylmercury Exposure Level and environmental mercury burden in tibet china
    Environmental Science & Technology, 2018
    Co-Authors: Shidong Ge, Menghan Cheng, Robert P. Mason, Zofia Baumann, Chenghao Yu, Yipeng He, Huizhong Shen, Long Chen, Qianggong Zhang
    Abstract:

    Highly elevated concentrations of total mercury (THg) and methylmercury (MeHg) were found in the municipal sewage in Tibet. Material flow analysis supports the hypothesis that these elevated concentrations are related to regular ingestion of Hg-containing Traditional Tibetan Medicine (TTM). In Tibet in 2015, a total of 3600 kg of THg was released from human body into the terrestrial environment as a result of TTM ingestion, amounting to 45% of the total THg release into the terrestrial environment in Tibet, hence substantially enhancing the environmental Hg burden. Regular ingestion of TTM leads to chronic Exposure of Tibetans to inorganic Hg (IHg) and MeHg, which is 34 to 3000-fold and 0–12-fold higher than from any other known dietary sources, respectively. Application of a human physiology model demonstrated that ingestion of TTM can induce high blood IHg and MeHg Levels in the human body. Moreover, 180 days would be required for the MeHg to be cleared out of the human body and return to the initial co...

  • Comment on ``Traditional Tibetan Medicine Induced High Methylmercury Exposure Level and Environmental Mercury Burden in Tibet, China''
    Environmental Science & Technology, 2018
    Co-Authors: Yipeng He, Shidong Ge, Menghan Cheng, Robert P. Mason, Zofia Baumann, Chenghao Yu, Huizhong Shen, Long Chen
    Abstract:

    Highly elevated concentrations of total mercury (THg) and methylmercury (MeHg) were found in the municipal sewage in Tibet. Material flow analysis supports the hypothesis that these elevated concentrations are related to regular ingestion of Hg-containing Traditional Tibetan Medicine (TTM). In Tibet in 2015, a total of 3600 kg of THg was released from human body into the terrestrial environment as a result of TTM ingestion, amounting to 45% of the total THg release into the terrestrial environment in Tibet, hence substantially enhancing the environmental Hg burden. Regular ingestion of TTM leads to chronic Exposure of Tibetans to inorganic Hg (IHg) and MeHg, which is 34 to 3000-fold and 0–12-fold higher than from any other known dietary sources, respectively. Application of a human physiology model demonstrated that ingestion of TTM can induce high blood IHg and MeHg Levels in the human body. Moreover, 180 days would be required for the MeHg to be cleared out of the human body and return to the initial co...

  • Traditional Tibetan Medicine Induced High Methylmercury Exposure Level and Environmental Mercury Burden in Tibet, China.
    Environmental science & technology, 2018
    Co-Authors: Yipeng He, Shidong Ge, Menghan Cheng, Robert P. Mason, Zofia Baumann, Chenghao Yu, Huizhong Shen, Long Chen
    Abstract:

    Highly elevated concentrations of total mercury (THg) and methylmercury (MeHg) were found in the municipal sewage in Tibet. Material flow analysis supports the hypothesis that these elevated concentrations are related to regular ingestion of Hg-containing Traditional Tibetan Medicine (TTM). In Tibet in 2015, a total of 3600 kg of THg was released from human body into the terrestrial environment as a result of TTM ingestion, amounting to 45% of the total THg release into the terrestrial environment in Tibet, hence substantially enhancing the environmental Hg burden. Regular ingestion of TTM leads to chronic Exposure of Tibetans to inorganic Hg (IHg) and MeHg, which is 34 to 3000-fold and 0-12-fold higher than from any other known dietary sources, respectively. Application of a human physiology model demonstrated that ingestion of TTM can induce high blood IHg and MeHg Levels in the human body. Moreover, 180 days would be required for the MeHg to be cleared out of the human body and return to the initial concentration i.e. prior to the ingestion of 1 TTM pill. Our analysis suggests that high Hg Level contained in TTM could be harmful to human health and elevate the environmental Hg burden in Tibet.