The Experts below are selected from a list of 9 Experts worldwide ranked by ideXlab platform
Sven Påhlman - One of the best experts on this subject based on the ideXlab platform.
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Protein kinase C-alpha and -epsilon are enriched in growth cones of differentiating SH-SY5Y human neuroblastoma cells.
Journal of Neuroscience Research, 1995Co-Authors: Vendela Parrow, Sofia Fagerstrom, G. Meyerson, Eewa Nånberg, Sven PåhlmanAbstract:SH-SY5Y cells differentiate into neuronal-like cells and Express Marker proteins like growth-associated protein (GAP-43) and neuropeptide tyrosine when treated with a low concentration (16 nM) of t ...
Vendela Parrow - One of the best experts on this subject based on the ideXlab platform.
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Protein kinase C-alpha and -epsilon are enriched in growth cones of differentiating SH-SY5Y human neuroblastoma cells.
Journal of Neuroscience Research, 1995Co-Authors: Vendela Parrow, Sofia Fagerstrom, G. Meyerson, Eewa Nånberg, Sven PåhlmanAbstract:SH-SY5Y cells differentiate into neuronal-like cells and Express Marker proteins like growth-associated protein (GAP-43) and neuropeptide tyrosine when treated with a low concentration (16 nM) of t ...
Sudarshan Suresh - One of the best experts on this subject based on the ideXlab platform.
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Down’s Syndrome Screening in the First Trimester with Additional Serum Markers: Indian Parameters
The Journal of Obstetrics and Gynecology of India, 2020Co-Authors: Seshandri Suresh, Howard S. Cuckle, Sujatha Jagadeesh, Kushagradhi Ghosh, Gayathri Vemavarapu, Tulika Taval, Sudarshan SureshAbstract:Objective To derive a risk calculation algorithm suitable for use in India when screening for Down’s syndrome using four first-trimester maternal serum Markers either alone or with ultrasound nuchal translucency (NT). Methods Stored maternal serum samples (− 20 °C) from 411 singleton unaffected pregnancies were retrieved and measured for pregnancy-associated plasma protein (PAPP-A), free β-human chorionic gonadotropin (hCG), placental growth factor and α-fetoprotein. Samples were taken at 10–13 weeks’ gestation. Equations were derived to Express Marker levels in multiples of the gestation-specific normal median, adjusted for maternal weight. Gaussian model parameters were derived and compared with six published non-Indian studies; NT parameters were derived from 27,647 women screened in India. On the basis of the maternal age distribution in 64,473 Indian women screened in 2016–2017, the model was used to predict test performance. Results The model predicted a detection rate for a serum-only protocol of 80% for a 5% false-positive rate. Using a 1 in 250 at term Down’s syndrome risk cut-off, the predicted detection rate was 78% and the false-positive rate was 4.1%. When NT was also included, the rates were 95% for 5% and 90% for 1.4%, respectively. Conclusion First-trimester screening using four serum Markers only can be carried out in India. Performance is expected to be similar to the second-trimester Quad test and will also facilitate early screening for preeclampsia and open spina bifida. A protocol of NT plus the four serum Markers enhances the performance compared with NT, PAPP-A and free β-hCG.
Sofia Fagerstrom - One of the best experts on this subject based on the ideXlab platform.
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Protein kinase C-alpha and -epsilon are enriched in growth cones of differentiating SH-SY5Y human neuroblastoma cells.
Journal of Neuroscience Research, 1995Co-Authors: Vendela Parrow, Sofia Fagerstrom, G. Meyerson, Eewa Nånberg, Sven PåhlmanAbstract:SH-SY5Y cells differentiate into neuronal-like cells and Express Marker proteins like growth-associated protein (GAP-43) and neuropeptide tyrosine when treated with a low concentration (16 nM) of t ...
G. Meyerson - One of the best experts on this subject based on the ideXlab platform.
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Protein kinase C-alpha and -epsilon are enriched in growth cones of differentiating SH-SY5Y human neuroblastoma cells.
Journal of Neuroscience Research, 1995Co-Authors: Vendela Parrow, Sofia Fagerstrom, G. Meyerson, Eewa Nånberg, Sven PåhlmanAbstract:SH-SY5Y cells differentiate into neuronal-like cells and Express Marker proteins like growth-associated protein (GAP-43) and neuropeptide tyrosine when treated with a low concentration (16 nM) of t ...
