The Experts below are selected from a list of 9 Experts worldwide ranked by ideXlab platform
Ichiro Katayama - One of the best experts on this subject based on the ideXlab platform.
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the synergistic effect of suplatast tosilate and tacrolimus hydrate ointment on adult atopic dermatitis with intractable Face Erythema
Nishi Nihon Hifuka, 2005Co-Authors: Motoi Takenaka, Bae Sang Jae, Shinichi Sato, Ichiro KatayamaAbstract:成人型アトピー性皮膚炎の難治性顔面紅斑を有する患者25例に対してタクロリムス軟膏で2週間の治療後，トシル酸スプラタストを併用した患者15例とタクロリムス軟膏単独で継続治療した10例に分けて，治療開始から10週までのトシル酸スプラタストの付加効果を検討した。その結果，全般改善度や皮疹の程度の改善効果に群間の差は認められなかった。しかし，タクロリムス軟膏の使用量はトシル酸スプラタスト併用群において有意な減少を認め(5.5g/週→ 1.2g/週)，さらにタクロリムス軟膏の中止率は単独治療群が0%であったのに対し，トシル酸スプラタスト併用群では33.3%とタクロリムス軟膏の減量効果が認められた。
Motoi Takenaka - One of the best experts on this subject based on the ideXlab platform.
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the synergistic effect of suplatast tosilate and tacrolimus hydrate ointment on adult atopic dermatitis with intractable Face Erythema
Nishi Nihon Hifuka, 2005Co-Authors: Motoi Takenaka, Bae Sang Jae, Shinichi Sato, Ichiro KatayamaAbstract:成人型アトピー性皮膚炎の難治性顔面紅斑を有する患者25例に対してタクロリムス軟膏で2週間の治療後，トシル酸スプラタストを併用した患者15例とタクロリムス軟膏単独で継続治療した10例に分けて，治療開始から10週までのトシル酸スプラタストの付加効果を検討した。その結果，全般改善度や皮疹の程度の改善効果に群間の差は認められなかった。しかし，タクロリムス軟膏の使用量はトシル酸スプラタスト併用群において有意な減少を認め(5.5g/週→ 1.2g/週)，さらにタクロリムス軟膏の中止率は単独治療群が0%であったのに対し，トシル酸スプラタスト併用群では33.3%とタクロリムス軟膏の減量効果が認められた。
Bae Sang Jae - One of the best experts on this subject based on the ideXlab platform.
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the synergistic effect of suplatast tosilate and tacrolimus hydrate ointment on adult atopic dermatitis with intractable Face Erythema
Nishi Nihon Hifuka, 2005Co-Authors: Motoi Takenaka, Bae Sang Jae, Shinichi Sato, Ichiro KatayamaAbstract:成人型アトピー性皮膚炎の難治性顔面紅斑を有する患者25例に対してタクロリムス軟膏で2週間の治療後，トシル酸スプラタストを併用した患者15例とタクロリムス軟膏単独で継続治療した10例に分けて，治療開始から10週までのトシル酸スプラタストの付加効果を検討した。その結果，全般改善度や皮疹の程度の改善効果に群間の差は認められなかった。しかし，タクロリムス軟膏の使用量はトシル酸スプラタスト併用群において有意な減少を認め(5.5g/週→ 1.2g/週)，さらにタクロリムス軟膏の中止率は単独治療群が0%であったのに対し，トシル酸スプラタスト併用群では33.3%とタクロリムス軟膏の減量効果が認められた。
Shinichi Sato - One of the best experts on this subject based on the ideXlab platform.
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the synergistic effect of suplatast tosilate and tacrolimus hydrate ointment on adult atopic dermatitis with intractable Face Erythema
Nishi Nihon Hifuka, 2005Co-Authors: Motoi Takenaka, Bae Sang Jae, Shinichi Sato, Ichiro KatayamaAbstract:成人型アトピー性皮膚炎の難治性顔面紅斑を有する患者25例に対してタクロリムス軟膏で2週間の治療後，トシル酸スプラタストを併用した患者15例とタクロリムス軟膏単独で継続治療した10例に分けて，治療開始から10週までのトシル酸スプラタストの付加効果を検討した。その結果，全般改善度や皮疹の程度の改善効果に群間の差は認められなかった。しかし，タクロリムス軟膏の使用量はトシル酸スプラタスト併用群において有意な減少を認め(5.5g/週→ 1.2g/週)，さらにタクロリムス軟膏の中止率は単独治療群が0%であったのに対し，トシル酸スプラタスト併用群では33.3%とタクロリムス軟膏の減量効果が認められた。
Giuseppe Micali - One of the best experts on this subject based on the ideXlab platform.
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a novel cosmetic antifungal anti inflammatory topical gel for the treatment of mild to moderate seborrheic dermatitis of the Face an open label trial utilizing clinical evaluation and Erythema directed digital photography
Giornale italiano di dermatologia e venereologia : organo ufficiale Società italiana di dermatologia e sifilografia, 2017Co-Authors: Federica Dall Oglio, Aurora Tedeschi, Carmelinda M Fusto, Francesco Lacarrubba, Franco Dinotta, Giuseppe MicaliAbstract:Background Topical cosmetic agents may play a role in the management of facial seborrheic dermatitis by reducing inflammation and scale production. Advanced digital photography, equipped with technology able to provide a detailed evaluation of red skin components corresponding to vascular flare (Erythema-directed digital photography), is a useful tool for evaluation of Erythema in patients affected by inflammatory dermatoses. The aim of this study was to assess the efficacy and safety of a new cosmetic topical gel containing piroctone olamine, lactoferrin, glycero-phospho-inositol, and Aloe vera for the treatment of facial seborrheic dermatitis by clinical and advanced digital photography evaluation. Methods An open-label, prospective, clinical trial was conducted on 25 patients with mild to moderate facial seborrheic dermatitis. Subjects were instructed to apply the gel twice daily for 45 days. The clinical efficacy was evaluated by measuring at baseline, at day 15 and 45 the degree of desquamation (by clinical examination) and Erythema (by digital photography technology via VISIA-CR™ system equipped with RBX™), using a 5-point severity scale, and pruritus (by subject-completed Visual Analogue Scale; scale from 0 to 100 mm). Finally, at baseline and at the end of the study, IGA (Investigator Global Assessment) was performed using a 5-point severity scale (from 0 = worsening to 4 = excellent response). Results At the end of treatment, a significant reduction (P 80% improvement) was recorded in 47.9% of patients, with no case of worsening. No signs of local intolerance were documented. Conclusions The tested cosmetic topical gel was effective in treating mild to moderate seborrheic dermatitis of the Face. Erythema-directed digital photography may represent a noteworthy tool for the therapeutic monitoring of facial seborrheic dermatitis and an important adjunct aid in the dermatologic clinical practice.
