The Experts below are selected from a list of 177 Experts worldwide ranked by ideXlab platform

Romano Danesi - One of the best experts on this subject based on the ideXlab platform.

  • Periorbital Necrotizing Fasciitis
    British Journal of Ophthalmology, 2009
    Co-Authors: Davide Lazzeri, Stefano Lazzeri, Michele Figus, Carlo Tascini, Guido Bocci, Livio Colizzi, Giordano Giannotti, Fulvio Lorenzetti, Daniele Gandini, Romano Danesi
    Abstract:

    Necrotizing fasciitis involving the periorbita is a devastating infection which potential outcomes range from severe disfigurement, loss of the eye, and even to death. Early recognition is critical though its initially nondistinctive appearance frequently delays diagnosis and treatment. Herein, the authors have performed a systematic review of previously published cases including clinical features, diagnoses and differential diagnoses, pathologic characteristics, and management. Periorbital necrotizing fasciitis is seen mainly in adults with a female predominance (54%); about half (47%) of the patients are previously healthy. The infection may follow local blunt trauma (17%), as well as penetrating injuries (22%) and Face Surgery (11%), whereas in about one-third of cases (28%) no cause is identified. Nonspecific erythema and localized painful swelling of the eyelids characterize the earliest manifestation of the disease, ensued by formation of blisters and necrosis of the periorbital skin and subcutaneous tissues. The causative organism in periorbital infection is mainly β-hemolytic Streptococcus alone (50%), occasionally in combination with Staphylococcus Aureus (18%). Mortality from this disease reveals an overall rate of 14.42%. The main risk factor for mortality is the type of causative organism since all reported cases of death were caused by β-hemolytic Streptococcus alone or associated with other organisms. Unlike necrotizing fasciitis affecting other body site, there is not a strong correlation with age greater than 50 years or the presence of associated chronic illness. Management of periorbital necrotizing fasciitis is then based on early distinction of symptoms and signs and aggressive multidisciplinary treatment. Thus, the delay between initial debridement and initiating parenteral broad-spectrum antibiotic therapy should be considered the most critical factor influencing morbidity and mortality.

Tina Xirou - One of the best experts on this subject based on the ideXlab platform.

  • Periorbital necrotizing fasciitis in a 69 year old patient. Medical management and use of hyperbaric oxygen as further adjunctive therapy
    Acta Ophthalmologica, 2014
    Co-Authors: Dm Portaliou, A Kouroupaki, Stamatina A. Kabanarou, I Karvela, E Feretis, Tina Xirou
    Abstract:

    Purpose To report a case of periorbital necrotizing fasciitis in a 69 year old patient that was successfully managed with the use of intravenous antibiotics and surgical debridement. In addition to the usual treatment modalities, Hyperbaric Oxygen (HBO) was used as further adjunctive therapy Methods A 69 year old male presented with profound swelling over the right eye and right side of forehead. On admission the physicians made the diagnosis of septic shock. Patient had no history of alcohol abuse, insect bite, infection, recent penetrating injury, blunt trauma, Face Surgery or known immunosuppression conditions such as diabetes mellitus. Orbital CT showed a predominantly preseptal soft-tissue swelling consistent with the diagnosis of periorbital necrotizing fasciitis Results Patient started on empiric treatment with broad-spectrum intravenous antibiotics that modified according to blood culture results few days later. Surgical debridement and microbiologic evaluation of the necrotic tissue were performed. Streptococcus pyogenes and Staphylococcus aureus were isolated from tissue samples. Patient was further treated with twenty sessions of Hyperbaric Oxygen Therapy. Complete resolution of the infection occurred six weeks after initial diagnosis. Conclusion Treatment of periorbital necrotizing fasciitis with intravenous antibiotics and surgical debridement can be further enhanced with Hyperbaric Oxygen sessions with promising results.

Davide Lazzeri - One of the best experts on this subject based on the ideXlab platform.

  • Periorbital Necrotizing Fasciitis
    British Journal of Ophthalmology, 2009
    Co-Authors: Davide Lazzeri, Stefano Lazzeri, Michele Figus, Carlo Tascini, Guido Bocci, Livio Colizzi, Giordano Giannotti, Fulvio Lorenzetti, Daniele Gandini, Romano Danesi
    Abstract:

    Necrotizing fasciitis involving the periorbita is a devastating infection which potential outcomes range from severe disfigurement, loss of the eye, and even to death. Early recognition is critical though its initially nondistinctive appearance frequently delays diagnosis and treatment. Herein, the authors have performed a systematic review of previously published cases including clinical features, diagnoses and differential diagnoses, pathologic characteristics, and management. Periorbital necrotizing fasciitis is seen mainly in adults with a female predominance (54%); about half (47%) of the patients are previously healthy. The infection may follow local blunt trauma (17%), as well as penetrating injuries (22%) and Face Surgery (11%), whereas in about one-third of cases (28%) no cause is identified. Nonspecific erythema and localized painful swelling of the eyelids characterize the earliest manifestation of the disease, ensued by formation of blisters and necrosis of the periorbital skin and subcutaneous tissues. The causative organism in periorbital infection is mainly β-hemolytic Streptococcus alone (50%), occasionally in combination with Staphylococcus Aureus (18%). Mortality from this disease reveals an overall rate of 14.42%. The main risk factor for mortality is the type of causative organism since all reported cases of death were caused by β-hemolytic Streptococcus alone or associated with other organisms. Unlike necrotizing fasciitis affecting other body site, there is not a strong correlation with age greater than 50 years or the presence of associated chronic illness. Management of periorbital necrotizing fasciitis is then based on early distinction of symptoms and signs and aggressive multidisciplinary treatment. Thus, the delay between initial debridement and initiating parenteral broad-spectrum antibiotic therapy should be considered the most critical factor influencing morbidity and mortality.

Dm Portaliou - One of the best experts on this subject based on the ideXlab platform.

  • Periorbital necrotizing fasciitis in a 69 year old patient. Medical management and use of hyperbaric oxygen as further adjunctive therapy
    Acta Ophthalmologica, 2014
    Co-Authors: Dm Portaliou, A Kouroupaki, Stamatina A. Kabanarou, I Karvela, E Feretis, Tina Xirou
    Abstract:

    Purpose To report a case of periorbital necrotizing fasciitis in a 69 year old patient that was successfully managed with the use of intravenous antibiotics and surgical debridement. In addition to the usual treatment modalities, Hyperbaric Oxygen (HBO) was used as further adjunctive therapy Methods A 69 year old male presented with profound swelling over the right eye and right side of forehead. On admission the physicians made the diagnosis of septic shock. Patient had no history of alcohol abuse, insect bite, infection, recent penetrating injury, blunt trauma, Face Surgery or known immunosuppression conditions such as diabetes mellitus. Orbital CT showed a predominantly preseptal soft-tissue swelling consistent with the diagnosis of periorbital necrotizing fasciitis Results Patient started on empiric treatment with broad-spectrum intravenous antibiotics that modified according to blood culture results few days later. Surgical debridement and microbiologic evaluation of the necrotic tissue were performed. Streptococcus pyogenes and Staphylococcus aureus were isolated from tissue samples. Patient was further treated with twenty sessions of Hyperbaric Oxygen Therapy. Complete resolution of the infection occurred six weeks after initial diagnosis. Conclusion Treatment of periorbital necrotizing fasciitis with intravenous antibiotics and surgical debridement can be further enhanced with Hyperbaric Oxygen sessions with promising results.

Michele Figus - One of the best experts on this subject based on the ideXlab platform.

  • Periorbital Necrotizing Fasciitis
    British Journal of Ophthalmology, 2009
    Co-Authors: Davide Lazzeri, Stefano Lazzeri, Michele Figus, Carlo Tascini, Guido Bocci, Livio Colizzi, Giordano Giannotti, Fulvio Lorenzetti, Daniele Gandini, Romano Danesi
    Abstract:

    Necrotizing fasciitis involving the periorbita is a devastating infection which potential outcomes range from severe disfigurement, loss of the eye, and even to death. Early recognition is critical though its initially nondistinctive appearance frequently delays diagnosis and treatment. Herein, the authors have performed a systematic review of previously published cases including clinical features, diagnoses and differential diagnoses, pathologic characteristics, and management. Periorbital necrotizing fasciitis is seen mainly in adults with a female predominance (54%); about half (47%) of the patients are previously healthy. The infection may follow local blunt trauma (17%), as well as penetrating injuries (22%) and Face Surgery (11%), whereas in about one-third of cases (28%) no cause is identified. Nonspecific erythema and localized painful swelling of the eyelids characterize the earliest manifestation of the disease, ensued by formation of blisters and necrosis of the periorbital skin and subcutaneous tissues. The causative organism in periorbital infection is mainly β-hemolytic Streptococcus alone (50%), occasionally in combination with Staphylococcus Aureus (18%). Mortality from this disease reveals an overall rate of 14.42%. The main risk factor for mortality is the type of causative organism since all reported cases of death were caused by β-hemolytic Streptococcus alone or associated with other organisms. Unlike necrotizing fasciitis affecting other body site, there is not a strong correlation with age greater than 50 years or the presence of associated chronic illness. Management of periorbital necrotizing fasciitis is then based on early distinction of symptoms and signs and aggressive multidisciplinary treatment. Thus, the delay between initial debridement and initiating parenteral broad-spectrum antibiotic therapy should be considered the most critical factor influencing morbidity and mortality.