The Experts below are selected from a list of 10959 Experts worldwide ranked by ideXlab platform
Mauricio Reyes - One of the best experts on this subject based on the ideXlab platform.
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a new soft tissue simulation strategy for cranio maxilloFacial surgery using Facial Muscle template model
Progress in Biophysics & Molecular Biology, 2010Co-Authors: Philipp Jurgens, Lutzpeter Nolte, Stefan Weber, Mauricio ReyesAbstract:We propose a computationally efficient, bio-mechanically relevant soft-tissue simulation method for cranio-maxilloFacial (CMF) surgery. Special emphasis is given to comply with the current clinical workflow. A template-based Facial Muscle prediction was introduced to avoid laborious segmentation from medical images. In addition, transversely isotropic mass-tensor model (MTM) was applied to realize the directional behavior of Facial Muscles in short computation time. Finally, sliding contact was incorporated to mimic realistic boundary condition in error-sensitive regions. Mechanical simulation result was compared with commercial finite element software. And retrospective validation study with postoperative scan of four CMF cases was performed.
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anatomically driven soft tissue simulation strategy for cranio maxilloFacial surgery using Facial Muscle template model
Medical Image Computing and Computer-Assisted Intervention, 2010Co-Authors: Philipp Jurgens, Lutzpeter Nolte, Mauricio ReyesAbstract:We propose a computationally efficient and biomechanically relevant soft-tissue simulation method for cranio-maxilloFacial (CMF) surgery. A template-based Facial Muscle reconstruction was introduced to minimize the efforts on preparing a patient-specific model. A transversely isotropic mass-tensor model (MTM) was adopted to realize the effect of directional property of Facial Muscles in reasonable computation time. Additionally, sliding contact around teeth and mucosa was considered for more realistic simulation. Retrospective validation study with postoperative scan of a real patient showed that there were considerable improvements in simulation accuracy by incorporating template-based Facial Muscle anatomy and sliding contact.
Philipp Jurgens - One of the best experts on this subject based on the ideXlab platform.
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a new soft tissue simulation strategy for cranio maxilloFacial surgery using Facial Muscle template model
Progress in Biophysics & Molecular Biology, 2010Co-Authors: Philipp Jurgens, Lutzpeter Nolte, Stefan Weber, Mauricio ReyesAbstract:We propose a computationally efficient, bio-mechanically relevant soft-tissue simulation method for cranio-maxilloFacial (CMF) surgery. Special emphasis is given to comply with the current clinical workflow. A template-based Facial Muscle prediction was introduced to avoid laborious segmentation from medical images. In addition, transversely isotropic mass-tensor model (MTM) was applied to realize the directional behavior of Facial Muscles in short computation time. Finally, sliding contact was incorporated to mimic realistic boundary condition in error-sensitive regions. Mechanical simulation result was compared with commercial finite element software. And retrospective validation study with postoperative scan of four CMF cases was performed.
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anatomically driven soft tissue simulation strategy for cranio maxilloFacial surgery using Facial Muscle template model
Medical Image Computing and Computer-Assisted Intervention, 2010Co-Authors: Philipp Jurgens, Lutzpeter Nolte, Mauricio ReyesAbstract:We propose a computationally efficient and biomechanically relevant soft-tissue simulation method for cranio-maxilloFacial (CMF) surgery. A template-based Facial Muscle reconstruction was introduced to minimize the efforts on preparing a patient-specific model. A transversely isotropic mass-tensor model (MTM) was adopted to realize the effect of directional property of Facial Muscles in reasonable computation time. Additionally, sliding contact around teeth and mucosa was considered for more realistic simulation. Retrospective validation study with postoperative scan of a real patient showed that there were considerable improvements in simulation accuracy by incorporating template-based Facial Muscle anatomy and sliding contact.
Lutzpeter Nolte - One of the best experts on this subject based on the ideXlab platform.
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a new soft tissue simulation strategy for cranio maxilloFacial surgery using Facial Muscle template model
Progress in Biophysics & Molecular Biology, 2010Co-Authors: Philipp Jurgens, Lutzpeter Nolte, Stefan Weber, Mauricio ReyesAbstract:We propose a computationally efficient, bio-mechanically relevant soft-tissue simulation method for cranio-maxilloFacial (CMF) surgery. Special emphasis is given to comply with the current clinical workflow. A template-based Facial Muscle prediction was introduced to avoid laborious segmentation from medical images. In addition, transversely isotropic mass-tensor model (MTM) was applied to realize the directional behavior of Facial Muscles in short computation time. Finally, sliding contact was incorporated to mimic realistic boundary condition in error-sensitive regions. Mechanical simulation result was compared with commercial finite element software. And retrospective validation study with postoperative scan of four CMF cases was performed.
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anatomically driven soft tissue simulation strategy for cranio maxilloFacial surgery using Facial Muscle template model
Medical Image Computing and Computer-Assisted Intervention, 2010Co-Authors: Philipp Jurgens, Lutzpeter Nolte, Mauricio ReyesAbstract:We propose a computationally efficient and biomechanically relevant soft-tissue simulation method for cranio-maxilloFacial (CMF) surgery. A template-based Facial Muscle reconstruction was introduced to minimize the efforts on preparing a patient-specific model. A transversely isotropic mass-tensor model (MTM) was adopted to realize the effect of directional property of Facial Muscles in reasonable computation time. Additionally, sliding contact around teeth and mucosa was considered for more realistic simulation. Retrospective validation study with postoperative scan of a real patient showed that there were considerable improvements in simulation accuracy by incorporating template-based Facial Muscle anatomy and sliding contact.
Stefan Weber - One of the best experts on this subject based on the ideXlab platform.
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a new soft tissue simulation strategy for cranio maxilloFacial surgery using Facial Muscle template model
Progress in Biophysics & Molecular Biology, 2010Co-Authors: Philipp Jurgens, Lutzpeter Nolte, Stefan Weber, Mauricio ReyesAbstract:We propose a computationally efficient, bio-mechanically relevant soft-tissue simulation method for cranio-maxilloFacial (CMF) surgery. Special emphasis is given to comply with the current clinical workflow. A template-based Facial Muscle prediction was introduced to avoid laborious segmentation from medical images. In addition, transversely isotropic mass-tensor model (MTM) was applied to realize the directional behavior of Facial Muscles in short computation time. Finally, sliding contact was incorporated to mimic realistic boundary condition in error-sensitive regions. Mechanical simulation result was compared with commercial finite element software. And retrospective validation study with postoperative scan of four CMF cases was performed.
A T Van Der Ploeg - One of the best experts on this subject based on the ideXlab platform.
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Facial Muscle weakness speech disorders and dysphagia are common in patients with classic infantile pompe disease treated with enzyme therapy
Journal of Inherited Metabolic Disease, 2012Co-Authors: C M Van Gelder, C I Van Capelle, Berendine J Ebbink, Moorvan I Nugteren, J M P Van Den Hout, M M Hakkesteegt, P A Van Doorn, Arnold J J Reuser, H H W De Gier, A T Van Der PloegAbstract:Classic infantile Pompe disease is an inherited generalized glycogen storage disorder caused by deficiency of lysosomal acid α-glucosidase. If left untreated, patients die before one year of age. Although enzyme-replacement therapy (ERT) has significantly prolonged lifespan, it has also revealed new aspects of the disease. For up to 11 years, we investigated the frequency and consequences of Facial-Muscle weakness, speech disorders and dysphagia in long-term survivors. Sequential photographs were used to determine the timing and severity of Facial-Muscle weakness. Using standardized articulation tests and fibreoptic endoscopic evaluation of swallowing, we investigated speech and swallowing function in a subset of patients. This study included 11 patients with classic infantile Pompe disease. Median age at the start of ERT was 2.4 months (range 0.1-8.3 months), and median age at the end of the study was 4.3 years (range 7.7 months −12.2 years). All patients developed Facial-Muscle weakness before the age of 15 months. Speech was studied in four patients. Articulation was disordered, with hypernasal resonance and reduced speech intelligibility in all four. Swallowing function was studied in six patients, the most important findings being ineffective swallowing with residues of food (5/6), penetration or aspiration (3/6), and reduced pharyngeal and/or laryngeal sensibility (2/6). We conclude that Facial-Muscle weakness, speech disorders and dysphagia are common in long-term survivors receiving ERT for classic infantile Pompe disease. To improve speech and reduce the risk for aspiration, early treatment by a speech therapist and regular swallowing assessments are recommended.
