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Torsten Zuberbier - One of the best experts on this subject based on the ideXlab platform.

  • physical urticarias and cholinergic urticaria
    Immunology and Allergy Clinics of North America, 2014
    Co-Authors: Marina Abajian, Sabine Altrichter, N Schoepke, Torsten Zuberbier
    Abstract:

    : Physical urticarias are a unique subgroup of chronic urticaria in which urticarial responses can be reproducibly induced by different specific physical stimuli acting on the skin. These conditions include urticaria Factitia/symptomatic dermographism, delayed pressure urticaria, cold contact urticaria, heat contact urticaria, solar urticaria, and vibratory urticaria/angioedema. Physical urticarias and cholinergic urticarias are diagnosed based on the patients' history and provocation tests including trigger threshold testing where possible. Treatment is mainly symptomatic. Many patients benefit from avoiding eliciting triggers, and desensitization to these triggers can be helpful in some physical urticarias and in cholinergic urticaria.

  • anti immunoglobulin e treatment of patients with recalcitrant physical urticaria
    International Archives of Allergy and Immunology, 2011
    Co-Authors: Martin Metz, Erika Ardelean, Frank Siebenhaar, K. Weller, Birgit Kessler, Karoline Krause, Sabine Altrichter, Markus Magerl, Torsten Zuberbier
    Abstract:

    In physical urticaria, exogenous physical factors such as thermal triggers, solar radiation and mechanic triggers including friction or pressure are responsible for the elicitation of symptoms in the skin of patients. Avoidance of the respective stimulus is usually difficult or impossible, and many patients are not sufficiently treated with standard antihistamines. We report that treatment with omalizumab (Xolair®) of 7 patients with physical urticarias [solar urticaria (n = 2), urticaria Factitia/symptomatic dermographism (n = 2), cold urticaria, delayed pressure urticaria and localized heat urticaria] resulted in complete symptom control within days after the first injection in 5 patients. In 1 patient, symptoms improved after increasing the dose of omalizumab, and 1 patient with localized heat urticaria did not respond significantly to treatment. Before anti-immunoglobulin E treatment, all patients had suffered from their physical urticaria for years and had had numerous unsuccessful therapies. The overall excellent responses to omalizumab treatment reported here indicate that anti-immunoglobulin E is a safe and effective treatment for recalcitrant physical urticarias.

Lvov Andrey - One of the best experts on this subject based on the ideXlab platform.

  • Self-inflicted lesions in dermatology: terminology and classification--a position paper from the European Society for Dermatology and Psychiatry (ESDaP)
    2013
    Co-Authors: Gieler Uwe, Consoli, Sylvie G., Tomás-aragones Lucía, Linder, Dennis M., Jemec, Gregor B. E., Poot Francoise, Szepietowski, Jacek C., De Korte John, Taube Klaus-michael, Lvov Andrey
    Abstract:

    The terminology, classification, diagnosis and treatment of self-inflicted dermatological lesions are subjects of open debate. The present study is the result of various meetings of a task force of dermatologists, psychiatrists and psychologists, all active in the field of psychodermatology, aimed at clarifying the terminology related to these disorders. A flow chart and glossary of terms and definitions are presented to facilitate the classification and management of self-inflicted skin lesions. Several terms are critically discussed, including: malingering; factitious disorders; Münchausen's syndrome; simulation; pathomimicry; skin picking syndrome and related skin damaging disorders; compulsive and impulsive skin picking; impulse control disorders; obsessive compulsive spectrum disorders; trichotillomania; dermatitis artefacta; Factitial dermatitis; acne excoriée; and neurotic and psychogenic excoriations. Self-inflicted skin lesions are often correlated with mental disorders and/or patho-logical behaviours, thus it is important for dermatologists to become as familiar as possible with the psychiatric and psychological aspects underlying these lesion

  • Self-inflicted lesions in dermatology: Terminology and classification - A position paper from the European Society for dermatology and psychiatry (ESDaP)
    'Acta Dermato-Venereologica', 2013
    Co-Authors: Gieler Uwe, Consoli, Sylvie G., Tomás-aragones Lucía, Poot Francoise, Szepietowski, Jacek C., De Korte John, Taube Klaus-michael, Linder Dennis, Jemec Gregor, Lvov Andrey
    Abstract:

    The terminology, classification, diagnosis and treatment of self-inflicted dermatological lesions are subjects of open debate. The present study is the result of various meetings of a task force of dermatologists, psychiatrists and psychologists, all active in the field of psychoder-matology, aimed at clarifying the terminology related to these disorders. A fow chart and glossary of terms and definitions are presented to facilitate the classification and management of self-inflicted skin lesions. Several terms are critically discussed, including: malingering; factitious disorders; Münchausen's syndrome; simulation; pathomimicry; skin picking syndrome and related skin damaging disorders; compulsive and impulsive skin picking; impulse control disorders; obsessive compulsive spectrum disorders; trichotillomania; dermatitis arte-facta; Factitial dermatitis; acne excoriée; and neurotic and psychogenic excoriations. Self-inflicted skin lesions are often correlated with mental disorders and/or pathological behaviours, thus it is important for dermatologists to become as familiar as possible with the psychiatric and psychological aspects underlying these lesions. © 2013 The Authors.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Richard K. Winkelmann - One of the best experts on this subject based on the ideXlab platform.

  • Weber-Christian panniculitis: A review of 30 cases with this diagnosis
    Journal of the American Academy of Dermatology, 1998
    Co-Authors: John W. White, Richard K. Winkelmann
    Abstract:

    Abstract Background: More than 60 years ago, Christian described a panniculitis that was later termed Weber-Christian disease . Objective: The purpose of this study was to investigate whether this is a specific disease or a nonspecific disease that embraces several specific conditions. Methods: We studied 30 cases diagnosed as Weber-Christian panniculitis and found it possible to make a more specific diagnosis. Results: In 12 patients, findings were compatible with erythema nodosum. Six patients had phlebitis or postphlebitic syndrome. Factitial panniculitis was diagnosed in five patients, and trauma had a role in the conditions of another three patients. Cytophagic panniculitis, lymphoma, and leukemia were recognized in one patient each. The lesion was lobular in almost all cases, and the presence of lipophagia was noted in 19 biopsy specimens. Granulomatous, neutrophilic, and lymphocytic pathologic changes were present in nine, eight, and eight tissue specimens, respectively. Conclusion: The recognition of distinct disease patterns of fat lesions as fat necrosis with pancreatic disease, α 1 -antitrypsin panniculitis, lupus and connective tissue disease panniculitis, involution lipoatrophy, lipomembranous panniculitis, Factitial panniculitis syndromes, calcification panniculitis, lipophagic lipoatrophy, and cytophagic panniculitis has lessened the need for a less specific panniculitis category. All these diseases have been reported in the literature as "Weber-Christian disease." Because separate and distinct forms of fat lesions have been described, we believe that the eponym should be abandoned and that more specific diagnoses should be made on the basis of pathogenesis or cause. (J Am Acad Dermatol 1998;39:56-62.)

Arslan Cheema - One of the best experts on this subject based on the ideXlab platform.

Waqas Ullah - One of the best experts on this subject based on the ideXlab platform.