Factitious Disease

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Keith H Baratz - One of the best experts on this subject based on the ideXlab platform.

  • Factitious Disease of periocular and facial skin
    American Journal of Ophthalmology, 1999
    Co-Authors: Seyda Ugurlu, George B Bartley, Clark C Otley, Keith H Baratz
    Abstract:

    PURPOSE: To describe the clinical appearance of Factitious (or self-inflicted) lesions on periocular skin and face. METHODS: All patients with Factitious cutaneous Disease who were examined at Mayo Clinic, Rochester, Minnesota, between 1985 and 1997 were identified. For patients with lesions on the face and periocular skin, the demographic features, clinical descriptive characteristics of their lesions, associated psychopathology, and treatments were ascertained. RESULTS: Of 38 patients with Factitious dermatitis, 18 (47%) had facial lesions. Of these 18 patients, 15 (83%) were female. The mean age (+/- SD) of the patients with facial lesions was 35.2 +/- 15.7 years (range, 9 to 66 years). Eight patients (44%) had neurotic excoriations, nine (50%) had dermatitis artefacta, and one (6%) had trichotillomania. The working diagnoses of five patients cared for initially in the Department of Ophthalmology were corneal epithelial and facial desquamation associated with severe pain of unknown cause, medial cicatricial ectropion of probable vasculitic cause, basal cell carcinoma of the nasojugal fold, recurrent preseptal cellulitis resistant to medical treatment, and madarosis of the upper eyelids of unknown cause. CONCLUSION: Cutaneous Factitious Disease may masquerade as numerous clinical entities and should be included in the differential diagnosis of lesions of the periocular skin.

Seyda Ugurlu - One of the best experts on this subject based on the ideXlab platform.

  • Factitious Disease of periocular and facial skin
    American Journal of Ophthalmology, 1999
    Co-Authors: Seyda Ugurlu, George B Bartley, Clark C Otley, Keith H Baratz
    Abstract:

    PURPOSE: To describe the clinical appearance of Factitious (or self-inflicted) lesions on periocular skin and face. METHODS: All patients with Factitious cutaneous Disease who were examined at Mayo Clinic, Rochester, Minnesota, between 1985 and 1997 were identified. For patients with lesions on the face and periocular skin, the demographic features, clinical descriptive characteristics of their lesions, associated psychopathology, and treatments were ascertained. RESULTS: Of 38 patients with Factitious dermatitis, 18 (47%) had facial lesions. Of these 18 patients, 15 (83%) were female. The mean age (+/- SD) of the patients with facial lesions was 35.2 +/- 15.7 years (range, 9 to 66 years). Eight patients (44%) had neurotic excoriations, nine (50%) had dermatitis artefacta, and one (6%) had trichotillomania. The working diagnoses of five patients cared for initially in the Department of Ophthalmology were corneal epithelial and facial desquamation associated with severe pain of unknown cause, medial cicatricial ectropion of probable vasculitic cause, basal cell carcinoma of the nasojugal fold, recurrent preseptal cellulitis resistant to medical treatment, and madarosis of the upper eyelids of unknown cause. CONCLUSION: Cutaneous Factitious Disease may masquerade as numerous clinical entities and should be included in the differential diagnosis of lesions of the periocular skin.

Danielle B Freedman - One of the best experts on this subject based on the ideXlab platform.

  • Munchausen syndrome and Factitious disorder: the role of the laboratory in its detection and diagnosis.
    Annals of clinical biochemistry, 2020
    Co-Authors: H Kinns, David Housley, Danielle B Freedman
    Abstract:

    The term Munchausen syndrome is used to describe the patient who chronically fabricates or induces illness with the sole intention of assuming the patient role. Such persons often have a close association with the medical profession and thus use their knowledge to falsify symptoms and laboratory specimens to mimic Disease. Cases of Factitious Disease have appeared in the literature originating from all medical specialties, and include such rare disorders as phaeochromocytoma and Bartter's syndrome. The laboratory can play a key role in the detection and diagnosis of Factitious disorders. Indeed discrepant biochemistry results may provide the first clue to the diagnosis. Laboratory staff should be particularly aware of highly variable test results and extreme abnormalities that are not consistent with the wider biochemical profile, suggesting sample tampering. Factitious disorder should also be included in the clinician's differential diagnosis when Disease presentation is unusual or an underlying cause cannot be found. Investigation to exclude or confirm Factitious disorder at an early stage can prevent unnecessary testing in the search for increasingly rare Diseases. Appropriate analyses may include screening tests for the detection of surreptitious drug administration or replication of a fabricated sample to confirm the method used. In all cases close communication between the clinician and laboratory is essential. This will ensure that appropriate tests are conducted particularly with regard to time critical and repeat tests.

  • Munchausen syndrome and Factitious disorder: the role of the laboratory in its detection and diagnosis.
    Annals of Clinical Biochemistry, 2013
    Co-Authors: H Kinns, David Housley, Danielle B Freedman
    Abstract:

    The term Munchausen syndrome is used to describe the patient who chronically fabricates or induces illness with the sole intention of assuming the patient role. Such persons often have a close association with the medical profession and thus use their knowledge to falsify symptoms and laboratory specimens to mimic Disease. Cases of Factitious Disease have appeared in the literature originating from all medical specialties, and include such rare disorders as phaeochromocytoma and Bartter's syndrome. The laboratory can play a key role in the detection and diagnosis of Factitious disorders. Indeed discrepant biochemistry results may provide the first clue to the diagnosis. Laboratory staff should be particularly aware of highly variable test results and extreme abnormalities that are not consistent with the wider biochemical profile, suggesting sample tampering. Factitious disorder should also be included in the clinician's differential diagnosis when Disease presentation is unusual or an underlying cause ca...

Clark C Otley - One of the best experts on this subject based on the ideXlab platform.

  • Factitious Disease of periocular and facial skin
    American Journal of Ophthalmology, 1999
    Co-Authors: Seyda Ugurlu, George B Bartley, Clark C Otley, Keith H Baratz
    Abstract:

    PURPOSE: To describe the clinical appearance of Factitious (or self-inflicted) lesions on periocular skin and face. METHODS: All patients with Factitious cutaneous Disease who were examined at Mayo Clinic, Rochester, Minnesota, between 1985 and 1997 were identified. For patients with lesions on the face and periocular skin, the demographic features, clinical descriptive characteristics of their lesions, associated psychopathology, and treatments were ascertained. RESULTS: Of 38 patients with Factitious dermatitis, 18 (47%) had facial lesions. Of these 18 patients, 15 (83%) were female. The mean age (+/- SD) of the patients with facial lesions was 35.2 +/- 15.7 years (range, 9 to 66 years). Eight patients (44%) had neurotic excoriations, nine (50%) had dermatitis artefacta, and one (6%) had trichotillomania. The working diagnoses of five patients cared for initially in the Department of Ophthalmology were corneal epithelial and facial desquamation associated with severe pain of unknown cause, medial cicatricial ectropion of probable vasculitic cause, basal cell carcinoma of the nasojugal fold, recurrent preseptal cellulitis resistant to medical treatment, and madarosis of the upper eyelids of unknown cause. CONCLUSION: Cutaneous Factitious Disease may masquerade as numerous clinical entities and should be included in the differential diagnosis of lesions of the periocular skin.

George B Bartley - One of the best experts on this subject based on the ideXlab platform.

  • Factitious Disease of periocular and facial skin
    American Journal of Ophthalmology, 1999
    Co-Authors: Seyda Ugurlu, George B Bartley, Clark C Otley, Keith H Baratz
    Abstract:

    PURPOSE: To describe the clinical appearance of Factitious (or self-inflicted) lesions on periocular skin and face. METHODS: All patients with Factitious cutaneous Disease who were examined at Mayo Clinic, Rochester, Minnesota, between 1985 and 1997 were identified. For patients with lesions on the face and periocular skin, the demographic features, clinical descriptive characteristics of their lesions, associated psychopathology, and treatments were ascertained. RESULTS: Of 38 patients with Factitious dermatitis, 18 (47%) had facial lesions. Of these 18 patients, 15 (83%) were female. The mean age (+/- SD) of the patients with facial lesions was 35.2 +/- 15.7 years (range, 9 to 66 years). Eight patients (44%) had neurotic excoriations, nine (50%) had dermatitis artefacta, and one (6%) had trichotillomania. The working diagnoses of five patients cared for initially in the Department of Ophthalmology were corneal epithelial and facial desquamation associated with severe pain of unknown cause, medial cicatricial ectropion of probable vasculitic cause, basal cell carcinoma of the nasojugal fold, recurrent preseptal cellulitis resistant to medical treatment, and madarosis of the upper eyelids of unknown cause. CONCLUSION: Cutaneous Factitious Disease may masquerade as numerous clinical entities and should be included in the differential diagnosis of lesions of the periocular skin.