The Experts below are selected from a list of 33 Experts worldwide ranked by ideXlab platform
Anthony Oregan - One of the best experts on this subject based on the ideXlab platform.
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high prevalence of obstructive Lung disease in non smoking Farmers the irish Farmers Lung health study
Respiratory Medicine, 2016Co-Authors: Breda Cushen, Imran Sulaiman, Noreen Donoghue, Donna Langan, Tara Cahill, Eimear Nic Dhonncha, Olivia Healy, Fiona Keegan, Mark Browne, Anthony OreganAbstract:Abstract Background Mortality rates within the Irish farming community are increasing, whilst that of the general population falls. The aim of this cross-sectional study was to determine the prevalence of respiratory disease amongst Irish Farmers. Methods All study participants were farming volunteers attending an agricultural exhibition. Data collected by questionnaire included baseline demographics, respiratory history, presence of respiratory symptoms and occupational exposures. Spirometry was performed on all participants. Results Data from 372 Farmers was analysed. The majority were male (76%) with median age of 55 years. 61% were never smokers. 13% were previously diagnosed with airway disease (Chronic Obstructive Pulmonary Disease(COPD)/Asthma/Inhaler use) with 14% reporting hayfever/allergies. Almost two-thirds reported one or more chronic respiratory symptom. Forty-four (12%) had obstructive spirometry using fixed FEV 1 /FVC 1 /FVC Conclusion The majority of Irish Farmers are never smokers. They have a high prevalence of respiratory symptoms. 13% of never smokers have airflow obstruction (FEV 1 /FVC
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irish Farmers Lung health study a study of the respiratory health of the irish farming population
European Respiratory Journal, 2015Co-Authors: Breda Cushen, Imran Sulaiman, Noreen Donoghue, Donna Langan, Tara Cahill, Olivia Healy, Fiona Keegan, Mark Browne, Eimear Nic Donnacha, Anthony OreganAbstract:Introduction: International studies have shown a high prevalence of respiratory complaints amongst agricultural workers however there is little data regarding the prevalence of respiratory disease in the Irish farming population. A recent study has shown that Irish farmer's general health has lagged behind other professions for unclear reasons. Aim: We undertook a cross-sectional study to determine the prevalence of respiratory symptoms and airways disease amongst Irish Farmers. Methods: A key component was respiratory scientist measured spirometry. Investigator-delivered questionnaires collected baseline demographics, symptom data and possible exposures. All study participants were farming volunteers. Spirometry results were correlated with variables related to respiratory disease. Results: Data on 372 farming volunteers was included for analysis. Majority were male (76%) with median age 55 years. 61% were never smokers. 44(12%) had obstructive spirometry(Fixed FEV1/FVC ratio <0.70). Of those, two-thirds were never smokers. The presence of obstruction in never smokers was significantly associated with prior diagnosis of airways disease and self-reported hayfever/allergy, p<0.01. Almost two-thirds reported one or more respiratory symptom. There was no significant correlation between the presence of airflow obstruction and home/occupational exposures. Conclusion: This large comprehensive assessment of Lung disease in Irish Farmers demonstrates a remarkably high prevalence of obstructive Lung disease in non-smoking subjects compared with international levels. More detailed studies are needed to identify the workplace factors accounting for these findings.
Sherwood P Burge - One of the best experts on this subject based on the ideXlab platform.
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characteristics of hypersensitivity pneumonitis diagnosed by interstitial and occupational Lung disease multi disciplinary team consensus
Respiratory Medicine, 2019Co-Authors: A. S. Robertson, Justin M Mokhlis, Vicky C Moore, G A Burge, Parminder S Bhomra, Sherwood P Burge, Gareth WaltersAbstract:Abstract Introduction The causes of hypersensitivity pneumonitis (HP) in the UK are changing as working practices evolve, and metalworking fluid (MWF) is now a frequently reported causative exposure. We aimed to review and describe all cases of HP from our UK regional service, with respect to the causative exposure and diagnostic characteristics. Methods In a retrospective, cross-sectional study, we collected patient data for all 206 cases of HP diagnosed within our UK-based regional NHS interstitial and occupational Lung disease service, 2002–17. This included demographics, environmental and occupational exposures, clinical features, and diagnostic tests (CT imaging, bronchiolo-alveolar cell count, Lung function, histology). We grouped the data by cause (occupational, non-occupational and unknown) and by presence or absence of fibrosis on CT, in order to undertake hypothesis testing. Results Cases were occupational (n = 50), non-occupational (n = 56) or cryptogenic (n = 100) in aetiology. The commonest causes were birds = 37 (18%) and MWF = 36 (17%). Other occupational causes included humidifiers and household or commercial waste, but only one case of Farmers’ Lung. Cryptogenic cases were associated with significantly older age, female gender, lower Lung function parameters, fewer alveolar lymphocyte counts >20%, and fibrosis on CT; exposure information was missing in 22–33% of cryptogenic cases. Conclusion MWF is the commonest occupational cause of HP, where workers usually present with more acute/subacute features and less fibrosis on CT; refuse work is an emerging cause. Cryptogenic HP has a fibrotic phenotype, and a full occupational history should be taken, as historical workplace exposures may be relevant.
Breda Cushen - One of the best experts on this subject based on the ideXlab platform.
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high prevalence of obstructive Lung disease in non smoking Farmers the irish Farmers Lung health study
Respiratory Medicine, 2016Co-Authors: Breda Cushen, Imran Sulaiman, Noreen Donoghue, Donna Langan, Tara Cahill, Eimear Nic Dhonncha, Olivia Healy, Fiona Keegan, Mark Browne, Anthony OreganAbstract:Abstract Background Mortality rates within the Irish farming community are increasing, whilst that of the general population falls. The aim of this cross-sectional study was to determine the prevalence of respiratory disease amongst Irish Farmers. Methods All study participants were farming volunteers attending an agricultural exhibition. Data collected by questionnaire included baseline demographics, respiratory history, presence of respiratory symptoms and occupational exposures. Spirometry was performed on all participants. Results Data from 372 Farmers was analysed. The majority were male (76%) with median age of 55 years. 61% were never smokers. 13% were previously diagnosed with airway disease (Chronic Obstructive Pulmonary Disease(COPD)/Asthma/Inhaler use) with 14% reporting hayfever/allergies. Almost two-thirds reported one or more chronic respiratory symptom. Forty-four (12%) had obstructive spirometry using fixed FEV 1 /FVC 1 /FVC Conclusion The majority of Irish Farmers are never smokers. They have a high prevalence of respiratory symptoms. 13% of never smokers have airflow obstruction (FEV 1 /FVC
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irish Farmers Lung health study a study of the respiratory health of the irish farming population
European Respiratory Journal, 2015Co-Authors: Breda Cushen, Imran Sulaiman, Noreen Donoghue, Donna Langan, Tara Cahill, Olivia Healy, Fiona Keegan, Mark Browne, Eimear Nic Donnacha, Anthony OreganAbstract:Introduction: International studies have shown a high prevalence of respiratory complaints amongst agricultural workers however there is little data regarding the prevalence of respiratory disease in the Irish farming population. A recent study has shown that Irish farmer's general health has lagged behind other professions for unclear reasons. Aim: We undertook a cross-sectional study to determine the prevalence of respiratory symptoms and airways disease amongst Irish Farmers. Methods: A key component was respiratory scientist measured spirometry. Investigator-delivered questionnaires collected baseline demographics, symptom data and possible exposures. All study participants were farming volunteers. Spirometry results were correlated with variables related to respiratory disease. Results: Data on 372 farming volunteers was included for analysis. Majority were male (76%) with median age 55 years. 61% were never smokers. 44(12%) had obstructive spirometry(Fixed FEV1/FVC ratio <0.70). Of those, two-thirds were never smokers. The presence of obstruction in never smokers was significantly associated with prior diagnosis of airways disease and self-reported hayfever/allergy, p<0.01. Almost two-thirds reported one or more respiratory symptom. There was no significant correlation between the presence of airflow obstruction and home/occupational exposures. Conclusion: This large comprehensive assessment of Lung disease in Irish Farmers demonstrates a remarkably high prevalence of obstructive Lung disease in non-smoking subjects compared with international levels. More detailed studies are needed to identify the workplace factors accounting for these findings.
Gareth Walters - One of the best experts on this subject based on the ideXlab platform.
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characteristics of hypersensitivity pneumonitis diagnosed by interstitial and occupational Lung disease multi disciplinary team consensus
Respiratory Medicine, 2019Co-Authors: A. S. Robertson, Justin M Mokhlis, Vicky C Moore, G A Burge, Parminder S Bhomra, Sherwood P Burge, Gareth WaltersAbstract:Abstract Introduction The causes of hypersensitivity pneumonitis (HP) in the UK are changing as working practices evolve, and metalworking fluid (MWF) is now a frequently reported causative exposure. We aimed to review and describe all cases of HP from our UK regional service, with respect to the causative exposure and diagnostic characteristics. Methods In a retrospective, cross-sectional study, we collected patient data for all 206 cases of HP diagnosed within our UK-based regional NHS interstitial and occupational Lung disease service, 2002–17. This included demographics, environmental and occupational exposures, clinical features, and diagnostic tests (CT imaging, bronchiolo-alveolar cell count, Lung function, histology). We grouped the data by cause (occupational, non-occupational and unknown) and by presence or absence of fibrosis on CT, in order to undertake hypothesis testing. Results Cases were occupational (n = 50), non-occupational (n = 56) or cryptogenic (n = 100) in aetiology. The commonest causes were birds = 37 (18%) and MWF = 36 (17%). Other occupational causes included humidifiers and household or commercial waste, but only one case of Farmers’ Lung. Cryptogenic cases were associated with significantly older age, female gender, lower Lung function parameters, fewer alveolar lymphocyte counts >20%, and fibrosis on CT; exposure information was missing in 22–33% of cryptogenic cases. Conclusion MWF is the commonest occupational cause of HP, where workers usually present with more acute/subacute features and less fibrosis on CT; refuse work is an emerging cause. Cryptogenic HP has a fibrotic phenotype, and a full occupational history should be taken, as historical workplace exposures may be relevant.
Erkki O. Terho - One of the best experts on this subject based on the ideXlab platform.
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Asthma in patients with farmer's Lung during a five-year follow-up
Scandinavian journal of work environment & health, 1997Co-Authors: Jouko Kokkarinen, H. Tukiainen, Erkki O. TerhoAbstract:Objectives This study assessed the incidence of asthma in patients with farmer's Lung. Methods The study population consisted of 1031 patients who had occupational farmer's Lung diagnosed from 1983 to 1988. The cases of farmer's Lung were registered in the nationwide Register of Occupational Diseases by the Finnish Institute of Occupational Health, and all the patients in the study had received compensation from the insurance company for an occupational disease. The diagnosis of asthma was based on entitlement to a special refund for asthma medication costs from the national sickness insurance program. Results Seventy-four cases of asthma were found among Farmers with farmer's Lung up to the end of the 5 years following the year of the diagnosis for farmer's Lung. The prevalence of asthma was 1% in the year preceding the diagnosis. In the year of the diagnosis and during the 5 year of follow-up, asthma was diagnosed in an additional 6% of the patients. Conclusions The results of this study confirm previous findings of a low prevalence of asthma before the onset of farmer's Lung in small groups of patients. However, the results also indicate that the incidence of asthma increases during the first years after an episode of Farmers Lung. For example, in the present study, asthma was apparent in 7% of the patients 5 years after the diagnosis of farmer's Lung.
