The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform

Enhua Wang - One of the best experts on this subject based on the ideXlab platform.

  • variable ki67 proliferative index in 65 cases of nodular Fasciitis compared with fibrosarcoma and fibromatosis
    Diagnostic Pathology, 2013
    Co-Authors: Xuyong Lin, Liang Wang, Yong Zhang, Shundong Dai, Enhua Wang
    Abstract:

    Abstract Nodular Fasciitis is the most common pseudosarcomatous lesion of soft tissue. Ki67 was considered as a useful marker for distinguishing some benign and malignant lesions. To study the usefulness of Ki67 in diagnosis of nodular Fasciitis, the expression of Ki67 was examined by using immunostaining in 65 nodular Fasciitis specimens, 15 desmoid fibromatosis specimens and 20 fibrosarcoma specimens. The results showed that there was a variable Ki67 index in all 65 cases of nodular Fasciitis, and the mean labeling index was 23.71±15.01%. In majority (70.77%) of all cases,the index was ranged from 10% to 50%, in 6.15% (4/65) of cases the higher Ki67 index (over 50%) could be seen. The Ki67 proliferative index was closely related to duration of lesion, but not to age distribution, lesion size, sites of lesions and gender. Moreover, the mean proliferative index in desmoid fibromatosis and fibrosarcoma was 3.20±1.26% and 26.15±3.30% respectively. The mean Ki67 index of nodular Fasciitis was not significantly lower than fibrosarcoma, but higher than desmoid fibromatosis. The variable and high Ki67 index in nodular Fasciitis may pose a diagnostic challenge. We should not misdiagnose nodular Fasciitis as a sarcoma because of its high Ki67 index. The recurrence of nodular Fasciitis is rare; and the utility of Ki67 immunostaining may be not suitable for recurrence assessment in nodular Fasciitis.

  • variable ki67 proliferative index in 65 cases of nodular Fasciitis compared with fibrosarcoma and fibromatosis
    Diagnostic Pathology, 2013
    Co-Authors: Xuyong Lin, Liang Wang, Yong Zhang, Shundong Dai, Enhua Wang
    Abstract:

    Nodular Fasciitis is the most common pseudosarcomatous lesion of soft tissue. Ki67 was considered as a useful marker for distinguishing some benign and malignant lesions. To study the usefulness of Ki67 in diagnosis of nodular Fasciitis, the expression of Ki67 was examined by using immunostaining in 65 nodular Fasciitis specimens, 15 desmoid fibromatosis specimens and 20 fibrosarcoma specimens. The results showed that there was a variable Ki67 index in all 65 cases of nodular Fasciitis, and the mean labeling index was 23.71±15.01%. In majority (70.77%) of all cases,the index was ranged from 10% to 50%, in 6.15% (4/65) of cases the higher Ki67 index (over 50%) could be seen. The Ki67 proliferative index was closely related to duration of lesion, but not to age distribution, lesion size, sites of lesions and gender. Moreover, the mean proliferative index in desmoid fibromatosis and fibrosarcoma was 3.20±1.26% and 26.15±3.30% respectively. The mean Ki67 index of nodular Fasciitis was not significantly lower than fibrosarcoma, but higher than desmoid fibromatosis. The variable and high Ki67 index in nodular Fasciitis may pose a diagnostic challenge. We should not misdiagnose nodular Fasciitis as a sarcoma because of its high Ki67 index. The recurrence of nodular Fasciitis is rare; and the utility of Ki67 immunostaining may be not suitable for recurrence assessment in nodular Fasciitis. The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/4782335818876666

Xuyong Lin - One of the best experts on this subject based on the ideXlab platform.

  • variable ki67 proliferative index in 65 cases of nodular Fasciitis compared with fibrosarcoma and fibromatosis
    Diagnostic Pathology, 2013
    Co-Authors: Xuyong Lin, Liang Wang, Yong Zhang, Shundong Dai, Enhua Wang
    Abstract:

    Abstract Nodular Fasciitis is the most common pseudosarcomatous lesion of soft tissue. Ki67 was considered as a useful marker for distinguishing some benign and malignant lesions. To study the usefulness of Ki67 in diagnosis of nodular Fasciitis, the expression of Ki67 was examined by using immunostaining in 65 nodular Fasciitis specimens, 15 desmoid fibromatosis specimens and 20 fibrosarcoma specimens. The results showed that there was a variable Ki67 index in all 65 cases of nodular Fasciitis, and the mean labeling index was 23.71±15.01%. In majority (70.77%) of all cases,the index was ranged from 10% to 50%, in 6.15% (4/65) of cases the higher Ki67 index (over 50%) could be seen. The Ki67 proliferative index was closely related to duration of lesion, but not to age distribution, lesion size, sites of lesions and gender. Moreover, the mean proliferative index in desmoid fibromatosis and fibrosarcoma was 3.20±1.26% and 26.15±3.30% respectively. The mean Ki67 index of nodular Fasciitis was not significantly lower than fibrosarcoma, but higher than desmoid fibromatosis. The variable and high Ki67 index in nodular Fasciitis may pose a diagnostic challenge. We should not misdiagnose nodular Fasciitis as a sarcoma because of its high Ki67 index. The recurrence of nodular Fasciitis is rare; and the utility of Ki67 immunostaining may be not suitable for recurrence assessment in nodular Fasciitis.

  • variable ki67 proliferative index in 65 cases of nodular Fasciitis compared with fibrosarcoma and fibromatosis
    Diagnostic Pathology, 2013
    Co-Authors: Xuyong Lin, Liang Wang, Yong Zhang, Shundong Dai, Enhua Wang
    Abstract:

    Nodular Fasciitis is the most common pseudosarcomatous lesion of soft tissue. Ki67 was considered as a useful marker for distinguishing some benign and malignant lesions. To study the usefulness of Ki67 in diagnosis of nodular Fasciitis, the expression of Ki67 was examined by using immunostaining in 65 nodular Fasciitis specimens, 15 desmoid fibromatosis specimens and 20 fibrosarcoma specimens. The results showed that there was a variable Ki67 index in all 65 cases of nodular Fasciitis, and the mean labeling index was 23.71±15.01%. In majority (70.77%) of all cases,the index was ranged from 10% to 50%, in 6.15% (4/65) of cases the higher Ki67 index (over 50%) could be seen. The Ki67 proliferative index was closely related to duration of lesion, but not to age distribution, lesion size, sites of lesions and gender. Moreover, the mean proliferative index in desmoid fibromatosis and fibrosarcoma was 3.20±1.26% and 26.15±3.30% respectively. The mean Ki67 index of nodular Fasciitis was not significantly lower than fibrosarcoma, but higher than desmoid fibromatosis. The variable and high Ki67 index in nodular Fasciitis may pose a diagnostic challenge. We should not misdiagnose nodular Fasciitis as a sarcoma because of its high Ki67 index. The recurrence of nodular Fasciitis is rare; and the utility of Ki67 immunostaining may be not suitable for recurrence assessment in nodular Fasciitis. The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/4782335818876666

Joseph Hamill - One of the best experts on this subject based on the ideXlab platform.

  • use of mri for volume estimation of tibialis posterior and plantar intrinsic foot muscles in healthy and chronic plantar Fasciitis limbs
    Clinical Biomechanics, 2012
    Co-Authors: Ryan Chang, Jane A Kentbraun, Joseph Hamill
    Abstract:

    Abstract Background Due to complexity of the plantar intrinsic foot muscles, little is known about their muscle architecture in vivo. Chronic plantar Fasciitis may be accompanied by muscle atrophy of plantar intrinsic foot muscles and tibialis posterior compromising the dynamic support of the foot prolonging the injury. Magnetic resonance images of the foot may be digitized to quantify muscle architecture. The first purpose of this study was to estimate in vivo the volume and distribution of healthy plantar intrinsic foot muscles. The second purpose was to determine whether chronic plantar Fasciitis is accompanied by atrophy of plantar intrinsic foot muscles and tibialis posterior. Methods Magnetic resonance images were taken bilaterally in eight subjects with unilateral plantar Fasciitis. Muscle perimeters were digitally outlined and muscle signal intensity thresholds were determined for each image for volume computation. Findings The mean volume of contractile tissue in healthy plantar intrinsic foot muscles was 113.3 cm3. Forefoot volumes of plantar Fasciitis plantar intrinsic foot muscles were 5.2% smaller than healthy feet (P = 0.03, ES = 0.26), but rearfoot (P = 0.26, ES = 0.08) and total foot volumes (P = 0.07) were similar. No differences were observed in tibialis posterior size. Interpretations While the total volume of plantar intrinsic foot muscles was similar in healthy and plantar Fasciitis feet, atrophy of the forefoot plantar intrinsic foot muscles may contribute to plantar Fasciitis by destabilizing the medial longitudinal arch. These results suggest that magnetic resonance imaging measures may be useful in understanding the etiology and rehabilitation of chronic plantar Fasciitis.

Liang Wang - One of the best experts on this subject based on the ideXlab platform.

  • variable ki67 proliferative index in 65 cases of nodular Fasciitis compared with fibrosarcoma and fibromatosis
    Diagnostic Pathology, 2013
    Co-Authors: Xuyong Lin, Liang Wang, Yong Zhang, Shundong Dai, Enhua Wang
    Abstract:

    Abstract Nodular Fasciitis is the most common pseudosarcomatous lesion of soft tissue. Ki67 was considered as a useful marker for distinguishing some benign and malignant lesions. To study the usefulness of Ki67 in diagnosis of nodular Fasciitis, the expression of Ki67 was examined by using immunostaining in 65 nodular Fasciitis specimens, 15 desmoid fibromatosis specimens and 20 fibrosarcoma specimens. The results showed that there was a variable Ki67 index in all 65 cases of nodular Fasciitis, and the mean labeling index was 23.71±15.01%. In majority (70.77%) of all cases,the index was ranged from 10% to 50%, in 6.15% (4/65) of cases the higher Ki67 index (over 50%) could be seen. The Ki67 proliferative index was closely related to duration of lesion, but not to age distribution, lesion size, sites of lesions and gender. Moreover, the mean proliferative index in desmoid fibromatosis and fibrosarcoma was 3.20±1.26% and 26.15±3.30% respectively. The mean Ki67 index of nodular Fasciitis was not significantly lower than fibrosarcoma, but higher than desmoid fibromatosis. The variable and high Ki67 index in nodular Fasciitis may pose a diagnostic challenge. We should not misdiagnose nodular Fasciitis as a sarcoma because of its high Ki67 index. The recurrence of nodular Fasciitis is rare; and the utility of Ki67 immunostaining may be not suitable for recurrence assessment in nodular Fasciitis.

  • variable ki67 proliferative index in 65 cases of nodular Fasciitis compared with fibrosarcoma and fibromatosis
    Diagnostic Pathology, 2013
    Co-Authors: Xuyong Lin, Liang Wang, Yong Zhang, Shundong Dai, Enhua Wang
    Abstract:

    Nodular Fasciitis is the most common pseudosarcomatous lesion of soft tissue. Ki67 was considered as a useful marker for distinguishing some benign and malignant lesions. To study the usefulness of Ki67 in diagnosis of nodular Fasciitis, the expression of Ki67 was examined by using immunostaining in 65 nodular Fasciitis specimens, 15 desmoid fibromatosis specimens and 20 fibrosarcoma specimens. The results showed that there was a variable Ki67 index in all 65 cases of nodular Fasciitis, and the mean labeling index was 23.71±15.01%. In majority (70.77%) of all cases,the index was ranged from 10% to 50%, in 6.15% (4/65) of cases the higher Ki67 index (over 50%) could be seen. The Ki67 proliferative index was closely related to duration of lesion, but not to age distribution, lesion size, sites of lesions and gender. Moreover, the mean proliferative index in desmoid fibromatosis and fibrosarcoma was 3.20±1.26% and 26.15±3.30% respectively. The mean Ki67 index of nodular Fasciitis was not significantly lower than fibrosarcoma, but higher than desmoid fibromatosis. The variable and high Ki67 index in nodular Fasciitis may pose a diagnostic challenge. We should not misdiagnose nodular Fasciitis as a sarcoma because of its high Ki67 index. The recurrence of nodular Fasciitis is rare; and the utility of Ki67 immunostaining may be not suitable for recurrence assessment in nodular Fasciitis. The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/4782335818876666

Shundong Dai - One of the best experts on this subject based on the ideXlab platform.

  • variable ki67 proliferative index in 65 cases of nodular Fasciitis compared with fibrosarcoma and fibromatosis
    Diagnostic Pathology, 2013
    Co-Authors: Xuyong Lin, Liang Wang, Yong Zhang, Shundong Dai, Enhua Wang
    Abstract:

    Abstract Nodular Fasciitis is the most common pseudosarcomatous lesion of soft tissue. Ki67 was considered as a useful marker for distinguishing some benign and malignant lesions. To study the usefulness of Ki67 in diagnosis of nodular Fasciitis, the expression of Ki67 was examined by using immunostaining in 65 nodular Fasciitis specimens, 15 desmoid fibromatosis specimens and 20 fibrosarcoma specimens. The results showed that there was a variable Ki67 index in all 65 cases of nodular Fasciitis, and the mean labeling index was 23.71±15.01%. In majority (70.77%) of all cases,the index was ranged from 10% to 50%, in 6.15% (4/65) of cases the higher Ki67 index (over 50%) could be seen. The Ki67 proliferative index was closely related to duration of lesion, but not to age distribution, lesion size, sites of lesions and gender. Moreover, the mean proliferative index in desmoid fibromatosis and fibrosarcoma was 3.20±1.26% and 26.15±3.30% respectively. The mean Ki67 index of nodular Fasciitis was not significantly lower than fibrosarcoma, but higher than desmoid fibromatosis. The variable and high Ki67 index in nodular Fasciitis may pose a diagnostic challenge. We should not misdiagnose nodular Fasciitis as a sarcoma because of its high Ki67 index. The recurrence of nodular Fasciitis is rare; and the utility of Ki67 immunostaining may be not suitable for recurrence assessment in nodular Fasciitis.

  • variable ki67 proliferative index in 65 cases of nodular Fasciitis compared with fibrosarcoma and fibromatosis
    Diagnostic Pathology, 2013
    Co-Authors: Xuyong Lin, Liang Wang, Yong Zhang, Shundong Dai, Enhua Wang
    Abstract:

    Nodular Fasciitis is the most common pseudosarcomatous lesion of soft tissue. Ki67 was considered as a useful marker for distinguishing some benign and malignant lesions. To study the usefulness of Ki67 in diagnosis of nodular Fasciitis, the expression of Ki67 was examined by using immunostaining in 65 nodular Fasciitis specimens, 15 desmoid fibromatosis specimens and 20 fibrosarcoma specimens. The results showed that there was a variable Ki67 index in all 65 cases of nodular Fasciitis, and the mean labeling index was 23.71±15.01%. In majority (70.77%) of all cases,the index was ranged from 10% to 50%, in 6.15% (4/65) of cases the higher Ki67 index (over 50%) could be seen. The Ki67 proliferative index was closely related to duration of lesion, but not to age distribution, lesion size, sites of lesions and gender. Moreover, the mean proliferative index in desmoid fibromatosis and fibrosarcoma was 3.20±1.26% and 26.15±3.30% respectively. The mean Ki67 index of nodular Fasciitis was not significantly lower than fibrosarcoma, but higher than desmoid fibromatosis. The variable and high Ki67 index in nodular Fasciitis may pose a diagnostic challenge. We should not misdiagnose nodular Fasciitis as a sarcoma because of its high Ki67 index. The recurrence of nodular Fasciitis is rare; and the utility of Ki67 immunostaining may be not suitable for recurrence assessment in nodular Fasciitis. The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/4782335818876666