The Experts below are selected from a list of 7179 Experts worldwide ranked by ideXlab platform
John Vissing - One of the best experts on this subject based on the ideXlab platform.
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Fatigue in patients with spinal muscular atrophy type ii and congenital myopathies evaluation of the Fatigue Severity Scale
Quality of Life Research, 2014Co-Authors: Ulla Werlauff, A Hojberg, R Firlaholme, Birgit F Steffensen, John VissingAbstract:Purpose The aim of this study was to evaluate whether the Fatigue Severity Scale (FSS) is an appropriate instrument to assess Fatigue in patients with spinal muscular atrophy type II (SMA II) and congenital myopathies (CM).
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Fatigue in patients with spinal muscular atrophy type II and congenital myopathies: evaluation of the Fatigue Severity Scale
Quality of Life Research, 2014Co-Authors: Ulla Werlauff, A Hojberg, Birgit F Steffensen, R. Firla-holme, John VissingAbstract:Purpose The aim of this study was to evaluate whether the Fatigue Severity Scale (FSS) is an appropriate instrument to assess Fatigue in patients with spinal muscular atrophy type II (SMA II) and congenital myopathies (CM). Methods FSS and visual analog Scale (VAS) were administered to 33 SMA II- and 72 CM patients. The psychometric properties of the FSS were evaluated by means of classical test theories for each of the disease groups. If abnormal Fatigue was present in the disease group, the construct of Fatigue was evaluated by means of focus group interviews. Results Fatigue was rare in SMA II patients, but very frequent in patients with CM. The cut-off score designating abnormal Fatigue (FSS score ≥ 4) was exceeded by 10 % of the SMA II patients in contrast to 76 % of the CM patients, of whom 52 % suffered from severe Fatigue (FSS score ≥ 5). Focus group interviews demonstrated that Fatigue had an adverse effect on motor function, level of energy, social relations, and identity, four themes that could be captured by the FSS. The FSS and VAS were strongly correlated in SMA II patients, but only moderately in CM patients. The psychometric properties indicated that the original FSS with nine items measures more than one construct of Fatigue, eliminating the first two items improved Scale properties. Conclusion This study demonstrates that Fatigue is characteristic in patients with CM, but not in patients with SMA II, in whom Fatigue does not seem to impact daily life. While Fatigue in CM and SMA II can be captured by FSS, omitting the first two items of the Scale will improve its properties and content validity, along with comprehension of the Scale itself.
Ulla Werlauff - One of the best experts on this subject based on the ideXlab platform.
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Fatigue in patients with spinal muscular atrophy type ii and congenital myopathies evaluation of the Fatigue Severity Scale
Quality of Life Research, 2014Co-Authors: Ulla Werlauff, A Hojberg, R Firlaholme, Birgit F Steffensen, John VissingAbstract:Purpose The aim of this study was to evaluate whether the Fatigue Severity Scale (FSS) is an appropriate instrument to assess Fatigue in patients with spinal muscular atrophy type II (SMA II) and congenital myopathies (CM).
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Fatigue in patients with spinal muscular atrophy type II and congenital myopathies: evaluation of the Fatigue Severity Scale
Quality of Life Research, 2014Co-Authors: Ulla Werlauff, A Hojberg, Birgit F Steffensen, R. Firla-holme, John VissingAbstract:Purpose The aim of this study was to evaluate whether the Fatigue Severity Scale (FSS) is an appropriate instrument to assess Fatigue in patients with spinal muscular atrophy type II (SMA II) and congenital myopathies (CM). Methods FSS and visual analog Scale (VAS) were administered to 33 SMA II- and 72 CM patients. The psychometric properties of the FSS were evaluated by means of classical test theories for each of the disease groups. If abnormal Fatigue was present in the disease group, the construct of Fatigue was evaluated by means of focus group interviews. Results Fatigue was rare in SMA II patients, but very frequent in patients with CM. The cut-off score designating abnormal Fatigue (FSS score ≥ 4) was exceeded by 10 % of the SMA II patients in contrast to 76 % of the CM patients, of whom 52 % suffered from severe Fatigue (FSS score ≥ 5). Focus group interviews demonstrated that Fatigue had an adverse effect on motor function, level of energy, social relations, and identity, four themes that could be captured by the FSS. The FSS and VAS were strongly correlated in SMA II patients, but only moderately in CM patients. The psychometric properties indicated that the original FSS with nine items measures more than one construct of Fatigue, eliminating the first two items improved Scale properties. Conclusion This study demonstrates that Fatigue is characteristic in patients with CM, but not in patients with SMA II, in whom Fatigue does not seem to impact daily life. While Fatigue in CM and SMA II can be captured by FSS, omitting the first two items of the Scale will improve its properties and content validity, along with comprehension of the Scale itself.
Birgit F Steffensen - One of the best experts on this subject based on the ideXlab platform.
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Fatigue in patients with spinal muscular atrophy type ii and congenital myopathies evaluation of the Fatigue Severity Scale
Quality of Life Research, 2014Co-Authors: Ulla Werlauff, A Hojberg, R Firlaholme, Birgit F Steffensen, John VissingAbstract:Purpose The aim of this study was to evaluate whether the Fatigue Severity Scale (FSS) is an appropriate instrument to assess Fatigue in patients with spinal muscular atrophy type II (SMA II) and congenital myopathies (CM).
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Fatigue in patients with spinal muscular atrophy type II and congenital myopathies: evaluation of the Fatigue Severity Scale
Quality of Life Research, 2014Co-Authors: Ulla Werlauff, A Hojberg, Birgit F Steffensen, R. Firla-holme, John VissingAbstract:Purpose The aim of this study was to evaluate whether the Fatigue Severity Scale (FSS) is an appropriate instrument to assess Fatigue in patients with spinal muscular atrophy type II (SMA II) and congenital myopathies (CM). Methods FSS and visual analog Scale (VAS) were administered to 33 SMA II- and 72 CM patients. The psychometric properties of the FSS were evaluated by means of classical test theories for each of the disease groups. If abnormal Fatigue was present in the disease group, the construct of Fatigue was evaluated by means of focus group interviews. Results Fatigue was rare in SMA II patients, but very frequent in patients with CM. The cut-off score designating abnormal Fatigue (FSS score ≥ 4) was exceeded by 10 % of the SMA II patients in contrast to 76 % of the CM patients, of whom 52 % suffered from severe Fatigue (FSS score ≥ 5). Focus group interviews demonstrated that Fatigue had an adverse effect on motor function, level of energy, social relations, and identity, four themes that could be captured by the FSS. The FSS and VAS were strongly correlated in SMA II patients, but only moderately in CM patients. The psychometric properties indicated that the original FSS with nine items measures more than one construct of Fatigue, eliminating the first two items improved Scale properties. Conclusion This study demonstrates that Fatigue is characteristic in patients with CM, but not in patients with SMA II, in whom Fatigue does not seem to impact daily life. While Fatigue in CM and SMA II can be captured by FSS, omitting the first two items of the Scale will improve its properties and content validity, along with comprehension of the Scale itself.
A Hojberg - One of the best experts on this subject based on the ideXlab platform.
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Fatigue in patients with spinal muscular atrophy type ii and congenital myopathies evaluation of the Fatigue Severity Scale
Quality of Life Research, 2014Co-Authors: Ulla Werlauff, A Hojberg, R Firlaholme, Birgit F Steffensen, John VissingAbstract:Purpose The aim of this study was to evaluate whether the Fatigue Severity Scale (FSS) is an appropriate instrument to assess Fatigue in patients with spinal muscular atrophy type II (SMA II) and congenital myopathies (CM).
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Fatigue in patients with spinal muscular atrophy type II and congenital myopathies: evaluation of the Fatigue Severity Scale
Quality of Life Research, 2014Co-Authors: Ulla Werlauff, A Hojberg, Birgit F Steffensen, R. Firla-holme, John VissingAbstract:Purpose The aim of this study was to evaluate whether the Fatigue Severity Scale (FSS) is an appropriate instrument to assess Fatigue in patients with spinal muscular atrophy type II (SMA II) and congenital myopathies (CM). Methods FSS and visual analog Scale (VAS) were administered to 33 SMA II- and 72 CM patients. The psychometric properties of the FSS were evaluated by means of classical test theories for each of the disease groups. If abnormal Fatigue was present in the disease group, the construct of Fatigue was evaluated by means of focus group interviews. Results Fatigue was rare in SMA II patients, but very frequent in patients with CM. The cut-off score designating abnormal Fatigue (FSS score ≥ 4) was exceeded by 10 % of the SMA II patients in contrast to 76 % of the CM patients, of whom 52 % suffered from severe Fatigue (FSS score ≥ 5). Focus group interviews demonstrated that Fatigue had an adverse effect on motor function, level of energy, social relations, and identity, four themes that could be captured by the FSS. The FSS and VAS were strongly correlated in SMA II patients, but only moderately in CM patients. The psychometric properties indicated that the original FSS with nine items measures more than one construct of Fatigue, eliminating the first two items improved Scale properties. Conclusion This study demonstrates that Fatigue is characteristic in patients with CM, but not in patients with SMA II, in whom Fatigue does not seem to impact daily life. While Fatigue in CM and SMA II can be captured by FSS, omitting the first two items of the Scale will improve its properties and content validity, along with comprehension of the Scale itself.
Colin Green - One of the best experts on this subject based on the ideXlab platform.
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using the Fatigue Severity Scale to inform healthcare decision making in multiple sclerosis mapping to three quality adjusted life year measures eq 5d 3l sf 6d msis 8d
Health and Quality of Life Outcomes, 2019Co-Authors: E A Goodwin, Annie Hawton, Colin GreenAbstract:Background Fatigue has a major influence on the quality of life of people with multiple sclerosis. The Fatigue Severity Scale is a frequently used patient-reported measure of Fatigue impact, but does not generate the health state utility values required to inform cost-effectiveness analysis, limiting its applicability within decision-making contexts. The objective of this study was to use statistical mapping methods to convert Fatigue Severity Scale scores to health state utility values from three preference-based measures: the EQ-5D-3L, SF-6D and Multiple Sclerosis Impact Scale-8D.
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Using the Fatigue Severity Scale to inform healthcare decision-making in multiple sclerosis: mapping to three quality-adjusted life-year measures (EQ-5D-3L, SF-6D, MSIS-8D)
Health and Quality of Life Outcomes, 2019Co-Authors: E A Goodwin, Annie Hawton, Colin GreenAbstract:Fatigue has a major influence on the quality of life of people with multiple sclerosis. The Fatigue Severity Scale is a frequently used patient-reported measure of Fatigue impact, but does not generate the health state utility values required to inform cost-effectiveness analysis, limiting its applicability within decision-making contexts. The objective of this study was to use statistical mapping methods to convert Fatigue Severity Scale scores to health state utility values from three preference-based measures: the EQ-5D-3L, SF-6D and Multiple Sclerosis Impact Scale-8D. The relationships between the measures were estimated through regression analysis using cohort data from 1056 people with multiple sclerosis in South West England. Estimation errors were assessed and predictive performance of the best models as tested in a separate sample (n = 352). For the EQ-5D and the Multiple Sclerosis Impact Scale-8D, the best performing models used a censored least absolute deviation specification, with Fatigue Severity Scale total score, age and gender as predictors. For the SF-6D, the best performing model used an ordinary least squares specification, with Fatigue Severity Scale total score as the only predictor. Here we present algorithms to convert Fatigue Severity Scales scores to health state utility values based on three preference-based measures. These values may be used to estimate quality-adjusted life-years for use in cost-effectiveness analyses and to consider the health-related quality of life of people with multiple sclerosis, thereby informing health policy decisions.
