The Experts below are selected from a list of 11637 Experts worldwide ranked by ideXlab platform
Mette Hedegaard Thomsen - One of the best experts on this subject based on the ideXlab platform.
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Complex media from processing of agricultural crops for microbial Fermentation
Applied Microbiology and Biotechnology, 2005Co-Authors: Mette Hedegaard ThomsenAbstract:This mini-review describes the concept of the green biorefinery and lists a number of suitable agricultural by-products, which can be used for production of bioenergy and/or biochemicals. A process, in which one possible agricultural by-product from the green crop drying industry, brown juice, is converted to a basic, universal Fermentation Medium by lactic acid Fermentation, is outlined. The resulting all-round Fermentation Medium can be used for the production of many useful Fermentation products when added a carbohydrate source, which could possibly be another agricultural by-product. Two examples of such products—polylactic acid and l -lysine—are given. A cost calculation shows that this Fermentation Medium can be produced at a very low cost ≈1.7 Euro cent/kg, when taking into account that the green crop industry has expenses amounting to 270,000 Euro/year for disposal of the brown juice. A newly built lysine factory in Esbjerg, Denmark, can benefit from this process by buying a low price Medium for the Fermentation process instead of more expensive traditional Fermentation liquids such as corn steep liquor.
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Complex media from processing of agricultural crops for microbial Fermentation
Applied Microbiology and Biotechnology, 2005Co-Authors: Mette Hedegaard ThomsenAbstract:This mini-review describes the concept of the green biorefinery and lists a number of suitable agricultural by-products, which can be used for production of bioenergy and/or biochemicals. A process, in which one possible agricultural by-product from the green crop drying industry, brown juice, is converted to a basic, universal Fermentation Medium by lactic acid Fermentation, is outlined. The resulting all-round Fermentation Medium can be used for the production of many useful Fermentation products when added a carbohydrate source, which could possibly be another agricultural by-product. Two examples of such products-polylactic acid and L-lysine-are given. A cost calculation shows that this Fermentation Medium can be produced at a very low cost approximately 1.7 Euro cent/kg, when taking into account that the green crop industry has expenses amounting to 270,000 Euro/year for disposal of the brown juice. A newly built lysine factory in Esbjerg, Denmark, can benefit from this process by buying a low price Medium for the Fermentation process instead of more expensive traditional Fermentation liquids such as corn steep liquor.
C K M Tripathi - One of the best experts on this subject based on the ideXlab platform.
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strategies for Fermentation Medium optimization an in depth review
Frontiers in Microbiology, 2017Co-Authors: Vineeta Singh, Shafiul Haque, Ram Niwas, Akansha Srivastava, Mukesh Pasupuleti, C K M TripathiAbstract:Optimization of production Medium is required to maximize the metabolite yield. This can be achieved by using a wide range of techniques from classical “one factor-at-a-time” to modern statistical and mathematical techniques, viz. artificial neural network, genetic algorithm etc. Each technique has its own advantages and disadvantages, and there are the situations where these techniques are applied for obtaining best results. Use of various optimization techniques in combination also provides the required results. In this article an attempt has been made to review the currently used media optimization techniques applied during Fermentation process of metabolite production. Comparative analysis of the merits and the demerits of various conventional as well as modern optimization techniques have been done and logical selection basis has been given in the present review. This review will provide the rationale of selection of suitable technique for the media optimization employed during the Fermentation process of metabolite production.
Yajie Tang - One of the best experts on this subject based on the ideXlab platform.
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tuber melanosporum Fermentation Medium optimization by plackett burman design coupled with draper lin small composite design and desirability function
Bioresource Technology, 2010Co-Authors: Yajie TangAbstract:Abstract A novel method using Plackett–Burman design (PBD) coupled with Draper–Lin small composite design (SCD) and desirability function (DF) was developed to optimize Tuber melanosporum Fermentation Medium. Firstly, sucrose, yeast extract, peptone and Mg2+ were identified to be key Medium components by PBD. Secondly, in order to evaluate the relationships between responses and the identified key components, mathematical models were developed by SCD. Finally, by using DF, the responses were optimized simultaneously and the optimal concentration was located to be 73 g/L sucrose, 11 g/L yeast extract, 8 g/L peptone, and 46 mM Mg2+. Under the identified optimal conditions, the maximal biomass, the production of extracellular (EPS) and intracellular (IPS) polysaccharides was 25.10 ± 0.12 g/L, 3.88 ± 0.23 g/L and 2.87 ± 0.32 g/L, respectively, which agreed with the predicted values well. Compared with the basic Medium, the biomass, the production of EPS and IPS was enhanced by 54.4%, 71.7% and 124.2%, respectively.
Vineeta Singh - One of the best experts on this subject based on the ideXlab platform.
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strategies for Fermentation Medium optimization an in depth review
Frontiers in Microbiology, 2017Co-Authors: Vineeta Singh, Shafiul Haque, Ram Niwas, Akansha Srivastava, Mukesh Pasupuleti, C K M TripathiAbstract:Optimization of production Medium is required to maximize the metabolite yield. This can be achieved by using a wide range of techniques from classical “one factor-at-a-time” to modern statistical and mathematical techniques, viz. artificial neural network, genetic algorithm etc. Each technique has its own advantages and disadvantages, and there are the situations where these techniques are applied for obtaining best results. Use of various optimization techniques in combination also provides the required results. In this article an attempt has been made to review the currently used media optimization techniques applied during Fermentation process of metabolite production. Comparative analysis of the merits and the demerits of various conventional as well as modern optimization techniques have been done and logical selection basis has been given in the present review. This review will provide the rationale of selection of suitable technique for the media optimization employed during the Fermentation process of metabolite production.
Y. Saǧ Açikel - One of the best experts on this subject based on the ideXlab platform.
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Optimization of critical Medium components using response surface methodology for lipase production by Rhizopus delemar
Food and Bioproducts Processing, 2010Co-Authors: Ü Açikel, M. Erşan, Y. Saǧ AçikelAbstract:The production process of a 1,3-position specific lipase from Rhizopus delemar was optimized by response surface methodology (RSM) and a Box-Behnken experimental design was used to study the interactive effects of Fermentation Medium components on lipase activity and microorganism growth. Preliminary batch tests were employed to obtain the favorable conditions for lipase activity analysis and found that sucrose, molasses, yeast extract, sunflower oil, tween-80 have significant influences on the lipase production and microorganism growth. The concentrations of five Fermentation Medium components were optimized. Among five variables, molasses sucrose and yeast extract were identified as less significant variables for lipase production. The optimum Fermentation Medium composition for lipase production by R. delemar was sucrose concentration 4.19 g/L, molasses sucrose 1.32 g/L, yeast extract 0.53 g/L, sunflower oil 1.11% (v/v), and tween-80 1.80% (v/v). In these conditions, the biomass concentration of 4.52 g/L with a lipolytic activity of 1585 ??mol/L min was reached. ?? 2009 The Institution of Chemical Engineers.