The Experts below are selected from a list of 4557 Experts worldwide ranked by ideXlab platform
A Carmignani - One of the best experts on this subject based on the ideXlab platform.
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Fetal intracranial Hemorrhage is minor maternal trauma a possible pathogenetic factor
Ultrasound in Obstetrics & Gynecology, 2001Co-Authors: Francesca Anna Letizia Strigini, Giovanni Cioni, R Canapicchi, Vincenzo Nardini, P Capriello, A CarmignaniAbstract:Objective The occurrence of Fetal intracranial Hemorrhage before labor has been repeatedly observed. The aim of this study was to evaluate the sonographic appearance of Fetal intracranial Hemorrhage in relation to its location. Possible causative factors were also evaluated. Design Five consecutive cases of Fetal intracranial Hemorrhage were identified at a single ultrasound unit between 1996 and 1999. In utero magnetic resonance imaging was also performed in four of these cases. Autopsy was performed after pregnancy termination or intrauterine Fetal death (one case of each), and neurological follow-up was initiated in the three surviving infants. Results Hydrocephaly was the predominant sonographic finding associated with intraventricular or subependymal Hemorrhage; sonography provided the correct diagnosis in the former (two cases), whereas magnetic resonance imaging was necessary in the latter. Massive intraparenchymal Hemorrhage was depicted as an irregular echoic mass, whereas extradural Hemorrhage had a cystic appearance. History of minor maternal physical trauma without maternal or placental injury was elicited in all cases. Ultrasound examinations performed before or shortly after the trauma were available in all cases and showed normal Fetal anatomy. Conclusions The sonographic appearance of Fetal intracranial Hemorrhage is variable, depending on its location. Even though sonography detected an intracranial anomaly in all cases, magnetic resonance imaging was necessary to establish the hemorrhagic nature of isolated subependymal and extradural Hemorrhage. The similarity of histories involving minor maternal physical trauma in all cases, together with the absence of any known factor predisposing to Fetal Hemorrhage, may suggest that trauma is at least a contributing factor to the pathogenesis of Fetal intracranial Hemorrhage.
Kenichi Tanaka - One of the best experts on this subject based on the ideXlab platform.
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an experience of laser surgery for feto Fetal transfusion syndrome complicated with unexpected feto Fetal Hemorrhage in a case of monochorionic triamniotic triplets
Fetal Diagnosis and Therapy, 2006Co-Authors: K Ishii, Takeshi Murakoshi, Masahiro Numata, Akira Kikuchi, Koichi Takakuwa, Kenichi TanakaAbstract:Feto-Fetal transfusion syndrome (FFTS) in monochorionic triplets is a rare clinical entity which may share the principal adverse perinatal outcomes of twin-twin transfusion syndrome. Recently, favorable prognoses regarding morbidity and mortality in twins after selective laser photocoagulation of placental communicating vessels (SLPCV) have been described. But descriptions of this procedure in monochorionic triplet cases are limited. This is the case report of an experience of SLPCV applied to monochorionic triamniotic triplets with FFTS. Triplet A had polyhydramnios, while absent end-diastolic flow in the umbilical artery of triplet B, the triplet with anhydramnios, was persistent. Triplet C looked normal, vertical amniotic pocket and Doppler studies yielding normal results. At the beginning of the SLPCV procedure, feto-Fetal Hemorrhage, subsequent to the Fetal death of the donor triplet, occurred. Both surviving cofetuses showed persistent bradycardia; and 1 fetus died while the other recovered from the Fetal bradycardia. All vascular anastomoses between the 3 triplets could be identified and obliterated, requiring two trocars. Our fetoscopic observation revealed feto-Fetal Hemorrhage after demise of monochorionic triplet, which led to injury of other fetuses due to hypovolemia in an instant. In conclusion, SLPCV might be a valid option for FFTS in triplet cases, while further experience is required in order to evaluate the risks and benefits of this procedure in triplet cases.
Francesca Anna Letizia Strigini - One of the best experts on this subject based on the ideXlab platform.
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Fetal intracranial Hemorrhage is minor maternal trauma a possible pathogenetic factor
Ultrasound in Obstetrics & Gynecology, 2001Co-Authors: Francesca Anna Letizia Strigini, Giovanni Cioni, R Canapicchi, Vincenzo Nardini, P Capriello, A CarmignaniAbstract:Objective The occurrence of Fetal intracranial Hemorrhage before labor has been repeatedly observed. The aim of this study was to evaluate the sonographic appearance of Fetal intracranial Hemorrhage in relation to its location. Possible causative factors were also evaluated. Design Five consecutive cases of Fetal intracranial Hemorrhage were identified at a single ultrasound unit between 1996 and 1999. In utero magnetic resonance imaging was also performed in four of these cases. Autopsy was performed after pregnancy termination or intrauterine Fetal death (one case of each), and neurological follow-up was initiated in the three surviving infants. Results Hydrocephaly was the predominant sonographic finding associated with intraventricular or subependymal Hemorrhage; sonography provided the correct diagnosis in the former (two cases), whereas magnetic resonance imaging was necessary in the latter. Massive intraparenchymal Hemorrhage was depicted as an irregular echoic mass, whereas extradural Hemorrhage had a cystic appearance. History of minor maternal physical trauma without maternal or placental injury was elicited in all cases. Ultrasound examinations performed before or shortly after the trauma were available in all cases and showed normal Fetal anatomy. Conclusions The sonographic appearance of Fetal intracranial Hemorrhage is variable, depending on its location. Even though sonography detected an intracranial anomaly in all cases, magnetic resonance imaging was necessary to establish the hemorrhagic nature of isolated subependymal and extradural Hemorrhage. The similarity of histories involving minor maternal physical trauma in all cases, together with the absence of any known factor predisposing to Fetal Hemorrhage, may suggest that trauma is at least a contributing factor to the pathogenesis of Fetal intracranial Hemorrhage.
S.-l. Jacobson - One of the best experts on this subject based on the ideXlab platform.
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Fatal Fetal Hemorrhage and placental pathology. Report of three cases and a new setting.
Placenta, 2005Co-Authors: W.a. Schmidt, J.a. Affleck, S.-l. JacobsonAbstract:We report three cases of late third trimester Fetal death in utero consequent to Fetal exsanguination from the chorionic vasculature. In general, Fetal Hemorrhage is unusual, exsanguination is rare and the location and basis of the Hemorrhage varies widely. Intragestational and intrapartum Hemorrhage is far more often of maternal rather than Fetal origin. Even when severe, the former is almost always manageable whilst the latter may be clinically obscure, intractable, catastrophic and fatal. In this presentation, we review and characterize Fetal Hemorrhage by anatomical location and on the basis of its underlying origins. In our first two cases, the chorionic vascular failure is understood on the basis of mechanical factors, such as tearing by the presenting part or an amniotomy hook. Our third case demonstrates the first reported instance in which a severe chorionic vasculopathy has damaged a placental surface vessel sufficiently to permit spontaneous rupture and Fetal exsanguination.
Yoichi Aoki - One of the best experts on this subject based on the ideXlab platform.
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warfarin associated Fetal intracranial Hemorrhage in woman with mitral valve replacements a case report
American Journal of Perinatology, 2009Co-Authors: Hitoshi Masamoto, Hiroyuki Uehara, Keiko Mekaru, Tadakazu Uezato, Kaoru Sakumoto, Yoichi AokiAbstract:Warfarin-associated Fetal Hemorrhage is a fatal event. We report the case of a 39-year-old woman who had been taking warfarin for 23 years since undergoing mitral valve replacement. Thereafter, when she was found to be pregnant, the medication was switched to heparin from 6 to 21 weeks of gestation. Following this, she was prescribed oral warfarin again (3.5 mg per day), with a strict control of prothrombin time/international normalized ratio (PT/INR). At 23 weeks of gestation, Fetal intracranial Hemorrhage occurred because of maternal exposure to warfarin. Maternal PT/INR does not correlate well with the activity of warfarin in the fetus and currently, there is no direct way to prevent Fetal intracranial Hemorrhage. Hence, further research on the optimal coagulation therapy in pregnant women with valve replacement should be encouraged.