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C J De Groot - One of the best experts on this subject based on the ideXlab platform.

  • 207 pos termination of pregnancy for hypertensive disorders prior to Fetal Viability in the netherlands a retrospective cohort study in 10 dutch tertiary care centers
    Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 2015
    Co-Authors: L Van Eerden, Gerda G Zeeman, G C Christiaens, F P H A Vandenbussche, Hubertina C J Scheepers, J Van Eyck, J M Middledorp, Eva Pajkrt, J J Duvekot, C J De Groot
    Abstract:

    Objectives To ascertain the incidence and demographic data of TOP for hypertensive disorders at the limits of Fetal Viability. Methods We conducted a retrospective cohort study. All terminations for hypertensive disorders between 2000 and 2009 in the ten Dutch tertiary care centers with a gestational age between 22 and 28 weeks were included. In all cases the fetus was judged to be non-viable, either because of the low gestational age or because of the effects of the maternal condition on the fetus. There was no intention to intervene for Fetal indications. Results During the study period TOP for hypertensive disorders occurred in 0.8 promille (131/163.052) of all deliveries in these 10 centers, of which there were 126 singleton and five twin pregnancies. 94 women were nulliparous and 37 multiparous. The main indication for TOP was HELLP syndrome. General history revealed hypertension in 24 women (18.3%). History was unremarkable in 98 cases (75%). The mean gestational age at admission was 166 days ± 9.6 days (GA 23+5), and at delivery this was 173 days ± 9.7 days (GA 24 + 5 weeks). The mean birth weight was 472 ± 123 g (70%  Conclusions In 10 years there we identified 131 cases of TOP for hypertensive disorders prior to Fetal Viability in The Dutch tertiary care centers. Ninety-eight women (75%) had no preexisting maternal disease. Table 1. Indications for termination of pregnancy. N  = number. Indication N (%) HELLP syndrome 80 (61.1) Preeclampsia 40 (30.5) Eclampsia 7 (5.3) Refractory hypertension 4 (3) Disclosures L. van Eerden: None.

  • termination of pregnancy for maternal indications at the limits of Fetal Viability a retrospective cohort study in the dutch tertiary care centres
    BMJ Open, 2014
    Co-Authors: L Van Eerden, Gerda G Zeeman, F P H A Vandenbussche, Hubertina C J Scheepers, J Van Eyck, Eva Pajkrt, J J Duvekot, G C Pagechristiaens, Johanna M Middeldorp, C J De Groot
    Abstract:

    Objective Maternal morbidity, either pregnancy related or pre-existent, can become life threatening and of such severity as to warrant termination of pregnancy (TOP). In this situation, chances of Fetal survival are usually poor, either because of low gestational age and/or because of the Fetal effects of the maternal condition. Examples include severe growth restriction in pre-eclampsia and intrauterine infection due to the very early preterm prelabour rupture of membranes. There are very few reports on the prevalence of TOP for maternal indication at the limits of Fetal Viability. We investigated the prevalence of and indications for TOP on maternal indication in the 10 tertiary care centres in the Netherlands during the past decade. Study design We conducted a retrospective review of the medical records of all women who underwent TOP for maternal indications between 22 and 27 completed weeks of gestation in all 10 tertiary care centres from 2000 to 2009. Results During the study period, there were 1 929 470 deliveries; 163 052 (8.4%) of these took place in one of the 10 tertiary care centres and 177 pregnancies were terminated for severe maternal disease, 131 for hypertensive disorders, 29 for intrauterine infection and 17 for other reasons. The mean gestational age at TOP was 171 days (24 3/7 )±10 days. No maternal deaths were recorded. The overall perinatal mortality was 99.4%. Conclusions Over a 10-year period, TOP for maternal indications was performed in 1 in 1000 deliveries in the 10 Dutch tertiary care centres. Hypertensive disorders comprised three-quarters of the cases.

Brian M Mercer - One of the best experts on this subject based on the ideXlab platform.

  • the management of preterm premature rupture of the membranes near the limit of Fetal Viability
    American Journal of Obstetrics and Gynecology, 2009
    Co-Authors: Thaddeus Waters, Brian M Mercer
    Abstract:

    Preterm premature rupture of the membranes near the limit of Fetal Viability is an uncommon complication of pregnancy, affecting approximately 4 in 1000 gravidas. However, maternal, Fetal, and neonatal complications resulting from this condition are significant and include chorioamnionitis, pulmonary hypoplasia, restriction deformities, Fetal loss, and complications of extreme prematurity among surviving infants. In this article, we review the literature regarding pregnancy outcomes after preterm premature rupture of the membranes near the limit of Viability, and the data on traditional and nontraditional interventions to improve outcomes. An approach to patients who present with preterm premature rupture of the membranes near the limit of Viability will be proposed.

A Semmalar - One of the best experts on this subject based on the ideXlab platform.

  • Serum Progesterone as a Single Hormone toDetect Fetal Viability in cases of ThreatenedAbortion
    2017
    Co-Authors: A Semmalar
    Abstract:

    AIMS & OBJECTIVES : To assess the levels of serum progesterone in patients with threatened abortion and follow up the patients to find the pregnancy outcome. Serum Progesterone As A Single Hormone To Detect Fetal Viability In Cases of Threatened Abortion. Single serum progesterone value of > 25ng/ml has 97% chance of Fetal Viability. MATERIALS AND METHODS : Short-term prospective study. Period of study: From Jan - 2015 to Jan - 2016. Study was conducted at the department of Obstetrics and Gynecology in Coimbatore Medical College and Hospital. About 100 patients presenting to the antenatal/ Gynecology OP with history of spotting per vaginum were taken into study 2ml sample of blood was collected in serum test tube sent and the serum progesterone levels were noted. At around 5 months of gestation, an ultrasound done at antenatal OP for Fetal heart rate and thus Viability of the fetus was noted they were followed up pregnancy outcome was monitored. DISCUSSION : In my study out of 100 patients 15 patients lost follow up. Among the 85 patients 50 had viable pregnancy. Among the 26 patients of serum progesterone >25ng/ml,24 had viable pregnancy. P

  • serum progesterone as a single hormone todetect Fetal Viability in cases of threatenedabortion
    2017
    Co-Authors: A Semmalar
    Abstract:

    AIMS & OBJECTIVES : To assess the levels of serum progesterone in patients with threatened abortion and follow up the patients to find the pregnancy outcome. Serum Progesterone As A Single Hormone To Detect Fetal Viability In Cases of Threatened Abortion. Single serum progesterone value of > 25ng/ml has 97% chance of Fetal Viability. MATERIALS AND METHODS : Short-term prospective study. Period of study: From Jan - 2015 to Jan - 2016. Study was conducted at the department of Obstetrics and Gynecology in Coimbatore Medical College and Hospital. About 100 patients presenting to the antenatal/ Gynecology OP with history of spotting per vaginum were taken into study 2ml sample of blood was collected in serum test tube sent and the serum progesterone levels were noted. At around 5 months of gestation, an ultrasound done at antenatal OP for Fetal heart rate and thus Viability of the fetus was noted they were followed up pregnancy outcome was monitored. DISCUSSION : In my study out of 100 patients 15 patients lost follow up. Among the 85 patients 50 had viable pregnancy. Among the 26 patients of serum progesterone >25ng/ml,24 had viable pregnancy. P<0.01 Among 23 patients of Serum progesterone values of < 10 ng/ml none of them had viable pregnancy. Among 36 patients between 10-25ng/ml 26 had viable pregnancy and 10 had non viable pregnancy. Thus as progesterone values increases the chances of preterm labour also decreases. CONCLUSION : Thus proving single serum progesterone as effective marker to say that the pregnancy will be viable.

L Van Eerden - One of the best experts on this subject based on the ideXlab platform.

  • 207 pos termination of pregnancy for hypertensive disorders prior to Fetal Viability in the netherlands a retrospective cohort study in 10 dutch tertiary care centers
    Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 2015
    Co-Authors: L Van Eerden, Gerda G Zeeman, G C Christiaens, F P H A Vandenbussche, Hubertina C J Scheepers, J Van Eyck, J M Middledorp, Eva Pajkrt, J J Duvekot, C J De Groot
    Abstract:

    Objectives To ascertain the incidence and demographic data of TOP for hypertensive disorders at the limits of Fetal Viability. Methods We conducted a retrospective cohort study. All terminations for hypertensive disorders between 2000 and 2009 in the ten Dutch tertiary care centers with a gestational age between 22 and 28 weeks were included. In all cases the fetus was judged to be non-viable, either because of the low gestational age or because of the effects of the maternal condition on the fetus. There was no intention to intervene for Fetal indications. Results During the study period TOP for hypertensive disorders occurred in 0.8 promille (131/163.052) of all deliveries in these 10 centers, of which there were 126 singleton and five twin pregnancies. 94 women were nulliparous and 37 multiparous. The main indication for TOP was HELLP syndrome. General history revealed hypertension in 24 women (18.3%). History was unremarkable in 98 cases (75%). The mean gestational age at admission was 166 days ± 9.6 days (GA 23+5), and at delivery this was 173 days ± 9.7 days (GA 24 + 5 weeks). The mean birth weight was 472 ± 123 g (70%  Conclusions In 10 years there we identified 131 cases of TOP for hypertensive disorders prior to Fetal Viability in The Dutch tertiary care centers. Ninety-eight women (75%) had no preexisting maternal disease. Table 1. Indications for termination of pregnancy. N  = number. Indication N (%) HELLP syndrome 80 (61.1) Preeclampsia 40 (30.5) Eclampsia 7 (5.3) Refractory hypertension 4 (3) Disclosures L. van Eerden: None.

  • termination of pregnancy for maternal indications at the limits of Fetal Viability a retrospective cohort study in the dutch tertiary care centres
    BMJ Open, 2014
    Co-Authors: L Van Eerden, Gerda G Zeeman, F P H A Vandenbussche, Hubertina C J Scheepers, J Van Eyck, Eva Pajkrt, J J Duvekot, G C Pagechristiaens, Johanna M Middeldorp, C J De Groot
    Abstract:

    Objective Maternal morbidity, either pregnancy related or pre-existent, can become life threatening and of such severity as to warrant termination of pregnancy (TOP). In this situation, chances of Fetal survival are usually poor, either because of low gestational age and/or because of the Fetal effects of the maternal condition. Examples include severe growth restriction in pre-eclampsia and intrauterine infection due to the very early preterm prelabour rupture of membranes. There are very few reports on the prevalence of TOP for maternal indication at the limits of Fetal Viability. We investigated the prevalence of and indications for TOP on maternal indication in the 10 tertiary care centres in the Netherlands during the past decade. Study design We conducted a retrospective review of the medical records of all women who underwent TOP for maternal indications between 22 and 27 completed weeks of gestation in all 10 tertiary care centres from 2000 to 2009. Results During the study period, there were 1 929 470 deliveries; 163 052 (8.4%) of these took place in one of the 10 tertiary care centres and 177 pregnancies were terminated for severe maternal disease, 131 for hypertensive disorders, 29 for intrauterine infection and 17 for other reasons. The mean gestational age at TOP was 171 days (24 3/7 )±10 days. No maternal deaths were recorded. The overall perinatal mortality was 99.4%. Conclusions Over a 10-year period, TOP for maternal indications was performed in 1 in 1000 deliveries in the 10 Dutch tertiary care centres. Hypertensive disorders comprised three-quarters of the cases.

Thaddeus Waters - One of the best experts on this subject based on the ideXlab platform.

  • the management of preterm premature rupture of the membranes near the limit of Fetal Viability
    American Journal of Obstetrics and Gynecology, 2009
    Co-Authors: Thaddeus Waters, Brian M Mercer
    Abstract:

    Preterm premature rupture of the membranes near the limit of Fetal Viability is an uncommon complication of pregnancy, affecting approximately 4 in 1000 gravidas. However, maternal, Fetal, and neonatal complications resulting from this condition are significant and include chorioamnionitis, pulmonary hypoplasia, restriction deformities, Fetal loss, and complications of extreme prematurity among surviving infants. In this article, we review the literature regarding pregnancy outcomes after preterm premature rupture of the membranes near the limit of Viability, and the data on traditional and nontraditional interventions to improve outcomes. An approach to patients who present with preterm premature rupture of the membranes near the limit of Viability will be proposed.