The Experts below are selected from a list of 15 Experts worldwide ranked by ideXlab platform
Marc Quirynen - One of the best experts on this subject based on the ideXlab platform.
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gc ms analysis of breath odor compounds in liver patients
Journal of Chromatography B, 2008Co-Authors: Sandra Van Den Velde, Frederik Nevens, Paul Van Hee, Daniel Van Steenberghe, Marc QuirynenAbstract:Abstract Background Liver diseases can cause a sweet, musty aroma of the breath, called Fetor Hepaticus. Even in a stage of cirrhosis, the disease can be asymptomatic for many years. Breath analysis might be helpful to detect occult liver pathology. Study objective This study examined whether specific breath odor compounds can be found in liver patients, suffering from cirrhosis, which might be useful for diagnosis. Materials and methods Fifty-two liver patients and 50 healthy volunteers were enrolled. Alveolar air was analyzed by gas chromatography–mass spectrometry. Using discriminant analysis a model for liver disease was built. Results Dimethyl sulfide, acetone, 2-butanone and 2-pentanone were increased in breath of liver patients, while indole and dimethyl selenide were decreased. Sensitivity and specificity of the model were respectively 100% and 70%. Conclusions Fetor Hepaticus is caused by dimethyl sulfide and to a lower extent by ketones in alveolar air. Breath analysis by GC–MS makes it possible to discriminate patients with breath malodor related to hepatic pathologies.
Quirynen Marc - One of the best experts on this subject based on the ideXlab platform.
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GC-MS analysis of breath odor compounds in liver patients
'Elsevier BV', 2008Co-Authors: Van Den Velde Sandra, Nevens Frederik, Van Hee Paul, Van Steenberghe Daniel, Quirynen MarcAbstract:Background: Liver diseases can cause a sweet, musty aroma of the breath, called Fetor Hepaticus. Even in a stage of cirrhosis, the disease can be asymptomatic for many years. Breath analysis might be helpful to detect occult liver pathology.status: publishe
Sandra Van Den Velde - One of the best experts on this subject based on the ideXlab platform.
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gc ms analysis of breath odor compounds in liver patients
Journal of Chromatography B, 2008Co-Authors: Sandra Van Den Velde, Frederik Nevens, Paul Van Hee, Daniel Van Steenberghe, Marc QuirynenAbstract:Abstract Background Liver diseases can cause a sweet, musty aroma of the breath, called Fetor Hepaticus. Even in a stage of cirrhosis, the disease can be asymptomatic for many years. Breath analysis might be helpful to detect occult liver pathology. Study objective This study examined whether specific breath odor compounds can be found in liver patients, suffering from cirrhosis, which might be useful for diagnosis. Materials and methods Fifty-two liver patients and 50 healthy volunteers were enrolled. Alveolar air was analyzed by gas chromatography–mass spectrometry. Using discriminant analysis a model for liver disease was built. Results Dimethyl sulfide, acetone, 2-butanone and 2-pentanone were increased in breath of liver patients, while indole and dimethyl selenide were decreased. Sensitivity and specificity of the model were respectively 100% and 70%. Conclusions Fetor Hepaticus is caused by dimethyl sulfide and to a lower extent by ketones in alveolar air. Breath analysis by GC–MS makes it possible to discriminate patients with breath malodor related to hepatic pathologies.
Van Den Velde Sandra - One of the best experts on this subject based on the ideXlab platform.
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GC-MS analysis of breath odor compounds in liver patients
'Elsevier BV', 2008Co-Authors: Van Den Velde Sandra, Nevens Frederik, Van Hee Paul, Van Steenberghe Daniel, Quirynen MarcAbstract:Background: Liver diseases can cause a sweet, musty aroma of the breath, called Fetor Hepaticus. Even in a stage of cirrhosis, the disease can be asymptomatic for many years. Breath analysis might be helpful to detect occult liver pathology.status: publishe
Daniel Van Steenberghe - One of the best experts on this subject based on the ideXlab platform.
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gc ms analysis of breath odor compounds in liver patients
Journal of Chromatography B, 2008Co-Authors: Sandra Van Den Velde, Frederik Nevens, Paul Van Hee, Daniel Van Steenberghe, Marc QuirynenAbstract:Abstract Background Liver diseases can cause a sweet, musty aroma of the breath, called Fetor Hepaticus. Even in a stage of cirrhosis, the disease can be asymptomatic for many years. Breath analysis might be helpful to detect occult liver pathology. Study objective This study examined whether specific breath odor compounds can be found in liver patients, suffering from cirrhosis, which might be useful for diagnosis. Materials and methods Fifty-two liver patients and 50 healthy volunteers were enrolled. Alveolar air was analyzed by gas chromatography–mass spectrometry. Using discriminant analysis a model for liver disease was built. Results Dimethyl sulfide, acetone, 2-butanone and 2-pentanone were increased in breath of liver patients, while indole and dimethyl selenide were decreased. Sensitivity and specificity of the model were respectively 100% and 70%. Conclusions Fetor Hepaticus is caused by dimethyl sulfide and to a lower extent by ketones in alveolar air. Breath analysis by GC–MS makes it possible to discriminate patients with breath malodor related to hepatic pathologies.