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Chen Dan-qin - One of the best experts on this subject based on the ideXlab platform.

  • The relationship between the body mass index and the perinatal outcomes of gestational women with diabetes mellitus
    Chinese Journal of Practical Gynecology and Obstetrics, 2010
    Co-Authors: Chen Dan-qin
    Abstract:

    Objective To investigate the effect of maternal prepregnancy body mass index(BMI)and BMI gain during pregnancy on obstetric outcomes of gestational diabetes mellitus(GDM)women.Methods This study is a register-based prospective cohort study.238 pregnant women diagnosed with GDM at our institution between 2006 and 2007 were enrolled,all the women were instructed in the use of diet therapy to achieved targeted levels of glycemic control.Perinatal outcomes were observed and analyzed according to maternal prepregnancy body mass index(BMI)categories(normal weight group,overweight group,obese group)and BMI gain during pregnancy categories:A group(BMI gain 4),B group(4≤BMI gain≤6),C group(BMI gain6).Results The rates of preeclampsia and preterm delivery in obese group(26.0%,32.7%)were significantly higher than that in normal weight group(11.9%,8.3%)and obese group(10.8%,3.7%)(P0.05).The normal weight group have less Fetus Distress(8.3%)than overweight group(23.5%)and obese group(23.1%)(P0.05).In B group,there was significantly more preeclampsia(10.4%),polyhydramnios(10.4%),premature rupture of membrane(10.4%),Fetus Distress(11.3%),preterm delivery(8.0%)compared with the C group(22.2%,23.8%,25.3%,30.2%,30.2%).The rates of fetal macrosomia in C group(25.4%)were higher than that in A(6.0%)and B group(12.0%)(P0.05).The newborn of C group(28.6%)have more hypoglycemia than B group(16.0%)(P0.05).Conclusion The obese GDM women with BMI≥25 and BMI gain6 during pregnancy would have higher risk of adverse prenatal outcome such as preterm delivery,preeclampsia and Fetus Distress.The BMI gain during pregnancy of GDM women should be suitably controlled,and then the prenatal outcome would be enhanced.

Yan-hong Shang - One of the best experts on this subject based on the ideXlab platform.

  • Relationship between body mass index and perinatal outcomes of pregnant women with gestational diabetes mellitus(GDM)
    Central Plains Medical Journal, 2013
    Co-Authors: Qiong Wang, Yan-hong Shang
    Abstract:

    Objective To investigate the relationship between body mass index and perinatal outcomes in pregnant women with gestational diabetes mellitus (GDM).Methods Two hundred and thirty-eight cases of GDM in our institution between January 2006 and January 2007 were chosed,and they were divided into three groups by BMI,including normal weight group(18.5-23.0 kg/m2),overweight group(23.0-25.0 kg/m2) and obese group(≥25.0 kg/m2),divided into three groups by BMI increasing,including group A (＜ 4 kg/m2),group B (4-6 kg/m2) and group C (＞ 6 kg/m2).Results The rate of preeclampsia(26.0％) and preterm delivery(32.7％) in obese group were significantly higher than those in normal weight group(11.9％,8.3％) and obese group(10.8％,3.7％),the differences were statistically significant (P ＜ 0.05).The normal weight group had less Fetus Distress (8.3％) than overweight group(23.5％)and obese group(23.1％),the differences were statistically significant (P ＜ 0.05).In group B,the rates of preeclampsia(10.4％),polyhydramnios(10.4％),premature rupture of membrane(10.4％),Fetus Distress(11.3％),preterm delivery(8.0％) were more lower than those in group C(22.2％,23.8％,25.3％,30.2％,30.2％).The rate of fetal macrosomia in group C(25.4％) was higher than that in group A(6.0％) and group B(12.0％),the difference was statistically significant (P ＜ 0.05).The incidence of neonatal hypoglycemia of group C (28.6％) was higher than that of group B(16.0％),the difference was statistically significant (P ＜ 0.05).Conclusions The obese GDM women with BMI ≥ 25 kg/m2 and BMI increase ＞ 6 kg/m2 during pregnancy would have higher risk of adverse prenatal outcome such as preterm delivery,preeclampsia and Fetus Distress.The BMI gain during pregnancy of GDM women should be suitably controlled,and then the prenatal outcome would be enhanced. Key words: Gestational diabetes mellitus;  Perinatal outcomes;  Body mass index;  Obesity

Qiao Fu-yua - One of the best experts on this subject based on the ideXlab platform.

  • Expression of transforming growth fector beta 1(TGFβ1 )and its receptor 1(TGF-βR1) in placenta of patients with intrahepatic cholestasis of pregnancy
    Chinese Journal of Birth Health & Heredity, 2005
    Co-Authors: Qiao Fu-yua
    Abstract:

    Objective:To explore the expression of TGFβ1 and TGF-βR1 on the placenta of introhepatic cholestasis of pregnancy (ICP). Methods:S-P immunohistochemical technique was used. Results:⑴ Placentas obtained from women with ICP had villus edema, reducing of the size of the intervillous space and depressing blood vessel density of villus under light microscopy.⑵ TGFβ1 expressed in both of the villus trophoblast cell of placenta in women with and without ICP. But its expression were lower than those of in control group (P0.01). TGF-βR1 expressed in both of the villus trophoblast cell and blood vessel endodermis cell of placenta in women with and without ICP,its expression were lower than those of in control group (P0.01).Conclusion:The laigh expression of placental TGFβ1 and TGF-βR1 may lead Fetus abortion,Premature rupture of membranes and Fetus Distress in the womb.

Qiong Wang - One of the best experts on this subject based on the ideXlab platform.

  • Relationship between body mass index and perinatal outcomes of pregnant women with gestational diabetes mellitus(GDM)
    Central Plains Medical Journal, 2013
    Co-Authors: Qiong Wang, Yan-hong Shang
    Abstract:

    Objective To investigate the relationship between body mass index and perinatal outcomes in pregnant women with gestational diabetes mellitus (GDM).Methods Two hundred and thirty-eight cases of GDM in our institution between January 2006 and January 2007 were chosed,and they were divided into three groups by BMI,including normal weight group(18.5-23.0 kg/m2),overweight group(23.0-25.0 kg/m2) and obese group(≥25.0 kg/m2),divided into three groups by BMI increasing,including group A (＜ 4 kg/m2),group B (4-6 kg/m2) and group C (＞ 6 kg/m2).Results The rate of preeclampsia(26.0％) and preterm delivery(32.7％) in obese group were significantly higher than those in normal weight group(11.9％,8.3％) and obese group(10.8％,3.7％),the differences were statistically significant (P ＜ 0.05).The normal weight group had less Fetus Distress (8.3％) than overweight group(23.5％)and obese group(23.1％),the differences were statistically significant (P ＜ 0.05).In group B,the rates of preeclampsia(10.4％),polyhydramnios(10.4％),premature rupture of membrane(10.4％),Fetus Distress(11.3％),preterm delivery(8.0％) were more lower than those in group C(22.2％,23.8％,25.3％,30.2％,30.2％).The rate of fetal macrosomia in group C(25.4％) was higher than that in group A(6.0％) and group B(12.0％),the difference was statistically significant (P ＜ 0.05).The incidence of neonatal hypoglycemia of group C (28.6％) was higher than that of group B(16.0％),the difference was statistically significant (P ＜ 0.05).Conclusions The obese GDM women with BMI ≥ 25 kg/m2 and BMI increase ＞ 6 kg/m2 during pregnancy would have higher risk of adverse prenatal outcome such as preterm delivery,preeclampsia and Fetus Distress.The BMI gain during pregnancy of GDM women should be suitably controlled,and then the prenatal outcome would be enhanced. Key words: Gestational diabetes mellitus;  Perinatal outcomes;  Body mass index;  Obesity

Yan Wei-hong - One of the best experts on this subject based on the ideXlab platform.

  • Causal Analysis on Neonatal Asphyxia
    Journal of North Sichuan Medical College, 2010
    Co-Authors: Yan Wei-hong
    Abstract:

    Objective:To investigate the causes of neonatal asphyxia and to master resuscitation technique and lower the incidence rate. Methods:The authors analyzed the causes of 100 cases with neonatal asphyxia and treated by corresponding resuscitation. Results:Abnormal umbilical cord (37%),postponed secondary labor (25%) were main causes of neonatal asphyxia. The success rate was 98% with effective emergent treatment. Conclusion:It can effectively lower incidence of neonatal asphyxia to make a good antepartum guide,monitor intrapartum intensively,observe labor closely,prevent the Fetus Distress in uterus in time and to take a proper mode of delivery.