The Experts below are selected from a list of 2169 Experts worldwide ranked by ideXlab platform
Anne Marie Quinn - One of the best experts on this subject based on the ideXlab platform.
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protein kinase catalytic domain sequence database identification of conserved features of primary structure and classification of family members
Methods in Enzymology, 1991Co-Authors: Steven K. Hanks, Anne Marie QuinnAbstract:Publisher Summary To help cope with the rapidly expanding protein kinase family, a database of the catalytic domain amino acid sequences has been established. This database would be a useful resource for the initial classification of novel protein kinases and for other studies that require extensive sequence comparisons. The catalytic domain database is updated frequently and often includes new sequences before they can be found in the Genbank/EMBL/PIR resources. More importantly, the availability of this large group of sequences in a single file saves investigators from the tedious task of collecting them themselves. This chapter describes the current makeup of the catalytic domain database and present two examples of its use: analysis and graphic display of conserved catalytic domain residues using conservation plots and classification of protein kinases by phylogenetic mapping. A prerequisite for both of these tasks is a multiple sequence alignment. The protein kinase catalytic domain database file can be obtained electronically over Internet using the standard network file transfer program (FTP). The database file PKINASES.IG contains brief descriptions of the kinases and references for the sequences. One hundred and seventeen distinct sequences had been entered by mid-February, 1990. Seventy-five of these are taken from protein-serine/threonine kinases and 42 from protein-tyrosine kinases. Sixty-eight of the sequences are from vertebrate species, 24 from yeasts (both budding and fission), 18 from Drosophila, two from nematode, and one each from Aplysia, Aspergillus, Hydra, bean plant (Phaseolus), and avian erythroblastosis virus S13. 43 of the 68 current vertebrate entries are taken from human sources and twenty two of the remaining vertebrate sequences derive from four other mammals: bovine, rabbit, rat, and mouse.
Steven K. Hanks - One of the best experts on this subject based on the ideXlab platform.
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protein kinase catalytic domain sequence database identification of conserved features of primary structure and classification of family members
Methods in Enzymology, 1991Co-Authors: Steven K. Hanks, Anne Marie QuinnAbstract:Publisher Summary To help cope with the rapidly expanding protein kinase family, a database of the catalytic domain amino acid sequences has been established. This database would be a useful resource for the initial classification of novel protein kinases and for other studies that require extensive sequence comparisons. The catalytic domain database is updated frequently and often includes new sequences before they can be found in the Genbank/EMBL/PIR resources. More importantly, the availability of this large group of sequences in a single file saves investigators from the tedious task of collecting them themselves. This chapter describes the current makeup of the catalytic domain database and present two examples of its use: analysis and graphic display of conserved catalytic domain residues using conservation plots and classification of protein kinases by phylogenetic mapping. A prerequisite for both of these tasks is a multiple sequence alignment. The protein kinase catalytic domain database file can be obtained electronically over Internet using the standard network file transfer program (FTP). The database file PKINASES.IG contains brief descriptions of the kinases and references for the sequences. One hundred and seventeen distinct sequences had been entered by mid-February, 1990. Seventy-five of these are taken from protein-serine/threonine kinases and 42 from protein-tyrosine kinases. Sixty-eight of the sequences are from vertebrate species, 24 from yeasts (both budding and fission), 18 from Drosophila, two from nematode, and one each from Aplysia, Aspergillus, Hydra, bean plant (Phaseolus), and avian erythroblastosis virus S13. 43 of the 68 current vertebrate entries are taken from human sources and twenty two of the remaining vertebrate sequences derive from four other mammals: bovine, rabbit, rat, and mouse.
Jasleen Kaur - One of the best experts on this subject based on the ideXlab platform.
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file transfer Using Secure Sockets in Linux Environment
2015Co-Authors: Abhipal Singh, Gurneet Singh, Sethi Kavleen, Kaur Oberoi, Jasleen KaurAbstract:file transfer over a network is done in various ways and using different protocols. But a file transferred over a network is not secure. When the network architecture consists of hubs or is wireless then the packets are broadcasted to every computer on that network. In hubs these packets are broadcasted because a hub does not remember what all devices are attached to it. It just takes a packet and sends it on all its ports. Similarly in wireless networks the data packets are broadcasted. In normal circumstances, the computer devices which are supposed to get the file receive it and the other computers reject it. Now, the problem arises when a computer’s system is cracked and that computer starts accepting the data it is not supposed to accept. This is the case with packet sniffing. The files sent during a transaction may be captured or “sniffed ” by third party tools called “Sniffers”. If a sniffer is placed in promiscuous mode, then it can capture all the incoming datagrams and it can reconstruct the original file from those datagrams. To ensure privacy and security we will implement file transfer over Secure Sockets Layer (SSL) so that the file is not interpreted by a sniffer. SSL is a communications protocol layer. It intercepts traffic and provides security between client and the server. Encryption is used to guarantee secure communication in an insecure environment. The encryption/decryption algorithm used for the purpose is Caesar Cipher. First, a file transfer program will be developed using socket programming under Linux environment and then security will be implemented using the above encryption/decryption algorithm
Abhipal Singh - One of the best experts on this subject based on the ideXlab platform.
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file transfer Using Secure Sockets in Linux Environment
2015Co-Authors: Abhipal Singh, Gurneet Singh, Sethi Kavleen, Kaur Oberoi, Jasleen KaurAbstract:file transfer over a network is done in various ways and using different protocols. But a file transferred over a network is not secure. When the network architecture consists of hubs or is wireless then the packets are broadcasted to every computer on that network. In hubs these packets are broadcasted because a hub does not remember what all devices are attached to it. It just takes a packet and sends it on all its ports. Similarly in wireless networks the data packets are broadcasted. In normal circumstances, the computer devices which are supposed to get the file receive it and the other computers reject it. Now, the problem arises when a computer’s system is cracked and that computer starts accepting the data it is not supposed to accept. This is the case with packet sniffing. The files sent during a transaction may be captured or “sniffed ” by third party tools called “Sniffers”. If a sniffer is placed in promiscuous mode, then it can capture all the incoming datagrams and it can reconstruct the original file from those datagrams. To ensure privacy and security we will implement file transfer over Secure Sockets Layer (SSL) so that the file is not interpreted by a sniffer. SSL is a communications protocol layer. It intercepts traffic and provides security between client and the server. Encryption is used to guarantee secure communication in an insecure environment. The encryption/decryption algorithm used for the purpose is Caesar Cipher. First, a file transfer program will be developed using socket programming under Linux environment and then security will be implemented using the above encryption/decryption algorithm
Gurneet Singh - One of the best experts on this subject based on the ideXlab platform.
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file transfer Using Secure Sockets in Linux Environment
2015Co-Authors: Abhipal Singh, Gurneet Singh, Sethi Kavleen, Kaur Oberoi, Jasleen KaurAbstract:file transfer over a network is done in various ways and using different protocols. But a file transferred over a network is not secure. When the network architecture consists of hubs or is wireless then the packets are broadcasted to every computer on that network. In hubs these packets are broadcasted because a hub does not remember what all devices are attached to it. It just takes a packet and sends it on all its ports. Similarly in wireless networks the data packets are broadcasted. In normal circumstances, the computer devices which are supposed to get the file receive it and the other computers reject it. Now, the problem arises when a computer’s system is cracked and that computer starts accepting the data it is not supposed to accept. This is the case with packet sniffing. The files sent during a transaction may be captured or “sniffed ” by third party tools called “Sniffers”. If a sniffer is placed in promiscuous mode, then it can capture all the incoming datagrams and it can reconstruct the original file from those datagrams. To ensure privacy and security we will implement file transfer over Secure Sockets Layer (SSL) so that the file is not interpreted by a sniffer. SSL is a communications protocol layer. It intercepts traffic and provides security between client and the server. Encryption is used to guarantee secure communication in an insecure environment. The encryption/decryption algorithm used for the purpose is Caesar Cipher. First, a file transfer program will be developed using socket programming under Linux environment and then security will be implemented using the above encryption/decryption algorithm