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Gilson Teles Boaventura - One of the best experts on this subject based on the ideXlab platform.

  • Effects of Maternal Flaxseed Supplementation on Female Offspring of Diabetic Rats in Serum Concentration of Glucose, Insulin, and Thyroid Hormones.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vi, 2019
    Co-Authors: Akemi Suzuki, Gabriela Câmara Vicente, André Manoel Correia-santos, Luiz Guillermo Coca Velarde, Gilson Teles Boaventura
    Abstract:

    Abstract. Objective: This study aimed to evaluate the effect of maternal consumption of Flaxseed Flour and oil on serum concentrations of glucose, insulin, and thyroid hormones of the adult female ...

  • Can the indicators of chronic ethanol consumption be minimized by a continuous Flaxseed intake
    International journal of experimental pathology, 2018
    Co-Authors: Juliana Tomaz Pacheco Latini, Gabriela Câmara Vicente, Katia Calvi Lenzi De Almeida, Luis Guillermo Coca Velarde, Hildebrando Gomes Benedicto, Ângela Castro Resende, Michelle Teixeira Teixeira, Gilson Teles Boaventura
    Abstract:

    The aim of this study was to evaluate the use of Flaxseed in animals subjected to ethanol-induced hepatotoxicity. Twenty-four male rats were divided into four groups (n = 6): control group (CG) which received a control diet and water ad libitum; Flaxseed group (FG) which received control diet with an addition of 25% Flaxseed Flour and water ad libitum; ethanol control group (ECG) which received control diet and a solution of 10% ethanol (v/v) as the only liquid source; and ethanol Flaxseed group (EFG) which received control diet with an addition of 25% Flaxseed Flour and a solution of 10% ethanol (v/v) as the only liquid source. The animals were euthanized at 60 days, when blood was collected for biochemical analysis and liver was collected for histomorphometric analysis. Rats fed with diets containing Flaxseed showed lower values of alkaline phosphatase (P = 0.020) and lower concentration of total bilirubin (P = 0.006), direct bilirubin (P = 0.013) and indirect bilirubin (P = 0.018) compared to ECG and EFG. The groups receiving Flaxseed diets demonstrated higher expression of superoxide dismutase (SOD) enzyme (P 

  • effects of Flour or Flaxseed oil upon testis mass in rats subjected to early weaning
    Natural Product Research, 2018
    Co-Authors: Carlos Alberto Soares Da Costa, Carolina Ribeiro Pessanha, Bianca Ferolla Da Camara Boueri, Gilson Teles Boaventura
    Abstract:

    Study evaluates testis mass in rats subjected to early weaning and subsequently nourished with diet containing Flour or Flaxseed oil. Pups were weaned for separation from mothers at 14 days (early weaning, EW) and 21 days (control, C). After 21 days, the control group (C60) was nourished with control diet. EW was divided as: control (EWC60), Flaxseed Flour (EWFF60) and Flaxseed oil (EWFO60) group diets for the next 60 days. At 21st and 60th day, body mass, serum cholesterol and triglycerides and testis mass were evaluated. At 21 day, EW group showed lower (p < 0.05) body mass, serum cholesterol and testis mass. At 60 days, EWC60 and EWFO60 groups showed lower (p < 0.05) body mass (vs. C60 and EWFF60). EWFF60 group showed lower (p < 0.05) serum cholesterol (vs. EWC60 and EWFO60) and higher (p < 0.05) testis mass (vs. C60, EWC60 and EWFO60). Flaxseed Flour (vs. oil) was associated with higher testis mass following early weaning.

  • Effects of Flour or Flaxseed oil upon testis mass in rats subjected to early weaning.
    Natural Product Research, 2017
    Co-Authors: Carlos Alberto Soares Da Costa, Carolina Ribeiro Pessanha, Bianca Ferolla Da Camara Boueri, Gilson Teles Boaventura
    Abstract:

    Study evaluates testis mass in rats subjected to early weaning and subsequently nourished with diet containing Flour or Flaxseed oil. Pups were weaned for separation from mothers at 14 days (early weaning, EW) and 21 days (control, C). After 21 days, the control group (C60) was nourished with control diet. EW was divided as: control (EWC60), Flaxseed Flour (EWFF60) and Flaxseed oil (EWFO60) group diets for the next 60 days. At 21st and 60th day, body mass, serum cholesterol and triglycerides and testis mass were evaluated. At 21 day, EW group showed lower (p 

  • Incorporation of Flaxseed Flour as a Dietary Source for ALA Increases Bone Density and Strength in Post-Partum Female Rats
    Lipids, 2017
    Co-Authors: Danielle Cavalcante Ribeiro, Aline D’avila Pereira, Eduardo Moreira Da Silva, Carlos Alberto Soares Da Costa, Fernanda Carvalho De Santana, Jorge Mancini-filho, Gilson Teles Boaventura
    Abstract:

    In women, bone mass undergoes changes during pregnancy and the postpartum period, which has a risk for subsequent development of osteoporosis. Thus, the present study aims to evaluate the effects of Flaxseed Flour in femur quality during post-weaning of dam rats. After weaning, the rats were divided into control ( C , n  = 7) and experimental ( F , n  = 7) groups treated with a diet containing 25 g of Flaxseed Flour in the lactating period and 15 g in the maintenance period. After 51 days post-partum, serum hormone, fatty acids composition, bone compartments, computed tomography, and biomechanical analyses were determined. Food intake, length, body mass, hormone analysis, and total bone compartments showed similar results. For biomechanical and computed tomography analysis and fatty acids composition, the F group showed higher maximum force (+12%, p  

Carlos Alberto Soares Da Costa - One of the best experts on this subject based on the ideXlab platform.

  • effects of Flour or Flaxseed oil upon testis mass in rats subjected to early weaning
    Natural Product Research, 2018
    Co-Authors: Carlos Alberto Soares Da Costa, Carolina Ribeiro Pessanha, Bianca Ferolla Da Camara Boueri, Gilson Teles Boaventura
    Abstract:

    Study evaluates testis mass in rats subjected to early weaning and subsequently nourished with diet containing Flour or Flaxseed oil. Pups were weaned for separation from mothers at 14 days (early weaning, EW) and 21 days (control, C). After 21 days, the control group (C60) was nourished with control diet. EW was divided as: control (EWC60), Flaxseed Flour (EWFF60) and Flaxseed oil (EWFO60) group diets for the next 60 days. At 21st and 60th day, body mass, serum cholesterol and triglycerides and testis mass were evaluated. At 21 day, EW group showed lower (p < 0.05) body mass, serum cholesterol and testis mass. At 60 days, EWC60 and EWFO60 groups showed lower (p < 0.05) body mass (vs. C60 and EWFF60). EWFF60 group showed lower (p < 0.05) serum cholesterol (vs. EWC60 and EWFO60) and higher (p < 0.05) testis mass (vs. C60, EWC60 and EWFO60). Flaxseed Flour (vs. oil) was associated with higher testis mass following early weaning.

  • Flaxseed (linum usitatissimum) Flour contributes to bone health in adult male rats
    Nutrition (Burbank Los Angeles County Calif.), 2017
    Co-Authors: Duque Coutinho De Abreu Maíra, Bianca Ferolla Da Camara Boueri, Luanna Rodrigues Da Costa, Aline D’avila Pereira, Danielle Cavalcante Ribeiro, Eduardo Moreira Da Silva, Carlos Alberto Soares Da Costa, Rozeno Pessoa Letícia, Ribeiro Pessanha Carolina, Teles Boaventura Gilson
    Abstract:

    Abstract Objective This study evaluated effects of Flaxseed Flour diet on bone health in adult Wistar male rats at 180 d. Methods After birth, pups were randomly assigned: Control (C, n = 12) and Flaxseed Flour (FF, n = 12) diet during lactation period. At 21 d, pups were weaned and they continued to receive the control and experimental diet, respectively. At 180 d, body length, total bone structure, and femur and lumbar vertebrae were evaluated by dual-energy X-ray absorptiometry. Femoral and lumbar vertebra dimensions, biomechanical properties of femur, and serum osteocalcin were measured. Results FF produced greater (P  Conclusion This experimental study found that a diet containing Flaxseed Flour contributed to bone mineral density and femur resistance at 180 d.

  • Effects of Flour or Flaxseed oil upon testis mass in rats subjected to early weaning.
    Natural Product Research, 2017
    Co-Authors: Carlos Alberto Soares Da Costa, Carolina Ribeiro Pessanha, Bianca Ferolla Da Camara Boueri, Gilson Teles Boaventura
    Abstract:

    Study evaluates testis mass in rats subjected to early weaning and subsequently nourished with diet containing Flour or Flaxseed oil. Pups were weaned for separation from mothers at 14 days (early weaning, EW) and 21 days (control, C). After 21 days, the control group (C60) was nourished with control diet. EW was divided as: control (EWC60), Flaxseed Flour (EWFF60) and Flaxseed oil (EWFO60) group diets for the next 60 days. At 21st and 60th day, body mass, serum cholesterol and triglycerides and testis mass were evaluated. At 21 day, EW group showed lower (p 

  • Incorporation of Flaxseed Flour as a Dietary Source for ALA Increases Bone Density and Strength in Post-Partum Female Rats
    Lipids, 2017
    Co-Authors: Danielle Cavalcante Ribeiro, Aline D’avila Pereira, Eduardo Moreira Da Silva, Carlos Alberto Soares Da Costa, Fernanda Carvalho De Santana, Jorge Mancini-filho, Gilson Teles Boaventura
    Abstract:

    In women, bone mass undergoes changes during pregnancy and the postpartum period, which has a risk for subsequent development of osteoporosis. Thus, the present study aims to evaluate the effects of Flaxseed Flour in femur quality during post-weaning of dam rats. After weaning, the rats were divided into control ( C , n  = 7) and experimental ( F , n  = 7) groups treated with a diet containing 25 g of Flaxseed Flour in the lactating period and 15 g in the maintenance period. After 51 days post-partum, serum hormone, fatty acids composition, bone compartments, computed tomography, and biomechanical analyses were determined. Food intake, length, body mass, hormone analysis, and total bone compartments showed similar results. For biomechanical and computed tomography analysis and fatty acids composition, the F group showed higher maximum force (+12%, p  

  • Incorporation of Flaxseed Flour as a Dietary Source for ALA Increases Bone Density and Strength in Post-Partum Female Rats
    Lipids, 2017
    Co-Authors: Danielle Cavalcante Ribeiro, Aline D’avila Pereira, Eduardo Moreira Da Silva, Carlos Alberto Soares Da Costa, Fernanda Carvalho De Santana, Jorge Mancini-filho, Gilson Teles Boaventura
    Abstract:

    In women, bone mass undergoes changes during pregnancy and the postpartum period, which has a risk for subsequent development of osteoporosis. Thus, the present study aims to evaluate the effects of Flaxseed Flour in femur quality during post-weaning of dam rats. After weaning, the rats were divided into control (C, n = 7) and experimental (F, n = 7) groups treated with a diet containing 25 g of Flaxseed Flour in the lactating period and 15 g in the maintenance period. After 51 days post-partum, serum hormone, fatty acids composition, bone compartments, computed tomography, and biomechanical analyses were determined. Food intake, length, body mass, hormone analysis, and total bone compartments showed similar results. For biomechanical and computed tomography analysis and fatty acids composition, the F group showed higher maximum force (+12%, p < 0.05), breaking strength (+25%, p < 0.05), rigidity (+17%, p < 0.0001), and femoral head radiodensity (+15%, p < 0.05) and presented lower total polyunsaturated fatty acids (−17%, p < 0.0001) and arachidonic acid (−44%, p < 0.0001) and higher ALA (+695%, p < 0.0001) and EPA (+160%, p < 0.05). Fatty acids composition of Flaxseed Flour, as well as its protein profile and calcium content, were able to improve the bone quality, which may be associated with lower serum levels of arachidonic acid and higher EPA, showing an anti-inflammatory profile and increased deposition of organic matrix during the post-weaning period, and may result in prevention of future osteoporosis.

Carolina Ribeiro Pessanha - One of the best experts on this subject based on the ideXlab platform.

  • effects of Flour or Flaxseed oil upon testis mass in rats subjected to early weaning
    Natural Product Research, 2018
    Co-Authors: Carlos Alberto Soares Da Costa, Carolina Ribeiro Pessanha, Bianca Ferolla Da Camara Boueri, Gilson Teles Boaventura
    Abstract:

    Study evaluates testis mass in rats subjected to early weaning and subsequently nourished with diet containing Flour or Flaxseed oil. Pups were weaned for separation from mothers at 14 days (early weaning, EW) and 21 days (control, C). After 21 days, the control group (C60) was nourished with control diet. EW was divided as: control (EWC60), Flaxseed Flour (EWFF60) and Flaxseed oil (EWFO60) group diets for the next 60 days. At 21st and 60th day, body mass, serum cholesterol and triglycerides and testis mass were evaluated. At 21 day, EW group showed lower (p < 0.05) body mass, serum cholesterol and testis mass. At 60 days, EWC60 and EWFO60 groups showed lower (p < 0.05) body mass (vs. C60 and EWFF60). EWFF60 group showed lower (p < 0.05) serum cholesterol (vs. EWC60 and EWFO60) and higher (p < 0.05) testis mass (vs. C60, EWC60 and EWFO60). Flaxseed Flour (vs. oil) was associated with higher testis mass following early weaning.

  • Effects of Flour or Flaxseed oil upon testis mass in rats subjected to early weaning.
    Natural Product Research, 2017
    Co-Authors: Carlos Alberto Soares Da Costa, Carolina Ribeiro Pessanha, Bianca Ferolla Da Camara Boueri, Gilson Teles Boaventura
    Abstract:

    Study evaluates testis mass in rats subjected to early weaning and subsequently nourished with diet containing Flour or Flaxseed oil. Pups were weaned for separation from mothers at 14 days (early weaning, EW) and 21 days (control, C). After 21 days, the control group (C60) was nourished with control diet. EW was divided as: control (EWC60), Flaxseed Flour (EWFF60) and Flaxseed oil (EWFO60) group diets for the next 60 days. At 21st and 60th day, body mass, serum cholesterol and triglycerides and testis mass were evaluated. At 21 day, EW group showed lower (p 

  • Flaxseed Flour, compared to Flaxseed oil, contributes to femoral structure in male rats subjected to early weaning
    Food & Function, 2016
    Co-Authors: Carolina Ribeiro Pessanha, Bianca Ferolla Da Camara Boueri, Luanna Rodrigues Da Costa, Maitê Rocha Ferreira, Maíra Duque Coutinho De Abreu, Letícia Rozeno Pessoa, Aline D’avila Pereira, Danielle Cavalcante Ribeiro, Eduardo Moreira Da Silva, Carlos Alberto Soares Da Costa
    Abstract:

    The aim of this study was to analyze whether Flaxseed Flour or Flaxseed oil treatment contributes to femoral structure in male rats subjected to early weaning. Pups were weaned for separation from mothers at 14 days (early weaning, EW) or 21 days (control, C). After 21 days, the control (C60) was fed with the control diet. The EW group was divided based on control (EWC60), Flaxseed Flour (EWFF60) and Flaxseed oil (EWFO60) diets until 60 days. Femoral dimension, bone mineral density (BMD), bone mineral content (BMC), area and biomechanical properties were determined. EWFO60 showed lower (P < 0.05) femur mass. EWC60 and EWFO60 showed lower (P < 0.05) distance between epiphyses, diaphysis width and BMD. BMC was lower (P < 0.05) in EWC60 (vs. C60 and EWFF60). EWC60 and EWFO60 showed lower (P < 0.05) maximum force (vs. C60). Breaking strength was lower (P < 0.05) in EWFO60 (vs. C60). EWFF60 showed higher (P < 0.05) rigidity. Flaxseed Flour abbreviated the femoral fragility secondary to early weaning.

  • Effects of diet containing Flaxseed Flour (Linum usitatissimum) on body adiposity and bone health in young male rats
    Food & function, 2016
    Co-Authors: Carlos Alberto Soares Da Costa, Carolina Ribeiro Pessanha, Bianca Ferolla Da Camara Boueri, Maíra Duque Coutinho De Abreu, Letícia Rozeno Pessoa, Aline D’avila Pereira, Danielle Cavalcante Ribeiro, Paula Cristina Alves Da Silva, Aline De Sousa Dos Santos, Celly Cristina Alves Do Nascimento-saba
    Abstract:

    Flaxseed Flour has been described as an excellent alpha-linolenic acid source. This study was designed to evaluate the effects of Flaxseed Flour on body adiposity and bone health in rats fed a Flaxseed Flour diet during lactation until 90 days. At birth, male Wistar rats were randomly assigned to control (C) and experimental (FF) groups, whose dams were treated with a control or Flaxseed Flour diet, respectively, during lactation. At 21 days, pups were weaned and fed a control and experimental diet until 90 days. Food intake, body mass and length were evaluated during a 21–90 day period. At 90 days, composition by dual-energy X-ray absorptiometry, serum hormonal profile, intra-abdominal fat mass, and lumbar vertebra and femur analyses was determined. Differences were deemed significant at p < 0.05. The FF group displayed the following (P < 0.05): a higher total lean mass (+7%), a lower total (−16%) and intra-abdominal (−24%) fat mass, a smaller adipocyte area (−30%), a higher femoral mass (+5%), bone mineral density (+5%) and radiodensity (+20%), and a higher maximum force (+10%) and breaking strength (+11%). The Flaxseed Flour diet displayed functional properties related to body growth maintenance associated with a lower risk of developing metabolic alterations, obesity and bone fragility.

  • Flaxseed Flour linum usitatissinum consumption improves bone quality and decreases the adipocyte area of lactating rats in the post weaning period
    International Journal of Food Sciences and Nutrition, 2016
    Co-Authors: Danielle Cavalcante Ribeiro, Carolina Ribeiro Pessanha, Bianca Ferolla Da Camara Boueri, Maíra Duque Coutinho De Abreu, Paula Cristina Alves Da Silva, Aline De Sousa Dos Santos, Aline Davila Pereira, Fernanda Carvalho De Santana, Jorge Mancinifilho, Eduardo Moreira Da Silva
    Abstract:

    The aim of this work was to evaluate the effects of Flaxseed Flour in the intake on adiposity and femur structure of the lactating rats during the post-weaning period. After weaning, the lactating rats were divided into control (C, n = 6) and experimental (F, n = 6) groups treated with a diet containing Flaxseed Flour. Serum hormone and fatty acids composition, morphology of intra-abdominal adipocytes, computed tomography and biomechanical analyses of femur were determined. Food intake, body mass and hormone analysis have shown similar results. The F group showed the following (p < 0.05): lower arachidonic acid (-60%), total polyunsaturated fatty acids (-30%) and retroperitoneal adipocytes (-36%) area. Higher radiodensity of femoral head region (+29%) and higher maximum force (+18%), breaking strength (+18%) and rigidity (+31%). Fatty acid composition of Flaxseed Flour decreased the area of adipocytes and improved the bone quality, which may be associated with lower serum levels of arachidonic acid levels, during the post-weaning period.

Bianca Ferolla Da Camara Boueri - One of the best experts on this subject based on the ideXlab platform.

  • effects of Flour or Flaxseed oil upon testis mass in rats subjected to early weaning
    Natural Product Research, 2018
    Co-Authors: Carlos Alberto Soares Da Costa, Carolina Ribeiro Pessanha, Bianca Ferolla Da Camara Boueri, Gilson Teles Boaventura
    Abstract:

    Study evaluates testis mass in rats subjected to early weaning and subsequently nourished with diet containing Flour or Flaxseed oil. Pups were weaned for separation from mothers at 14 days (early weaning, EW) and 21 days (control, C). After 21 days, the control group (C60) was nourished with control diet. EW was divided as: control (EWC60), Flaxseed Flour (EWFF60) and Flaxseed oil (EWFO60) group diets for the next 60 days. At 21st and 60th day, body mass, serum cholesterol and triglycerides and testis mass were evaluated. At 21 day, EW group showed lower (p < 0.05) body mass, serum cholesterol and testis mass. At 60 days, EWC60 and EWFO60 groups showed lower (p < 0.05) body mass (vs. C60 and EWFF60). EWFF60 group showed lower (p < 0.05) serum cholesterol (vs. EWC60 and EWFO60) and higher (p < 0.05) testis mass (vs. C60, EWC60 and EWFO60). Flaxseed Flour (vs. oil) was associated with higher testis mass following early weaning.

  • Flaxseed (linum usitatissimum) Flour contributes to bone health in adult male rats
    Nutrition (Burbank Los Angeles County Calif.), 2017
    Co-Authors: Duque Coutinho De Abreu Maíra, Bianca Ferolla Da Camara Boueri, Luanna Rodrigues Da Costa, Aline D’avila Pereira, Danielle Cavalcante Ribeiro, Eduardo Moreira Da Silva, Carlos Alberto Soares Da Costa, Rozeno Pessoa Letícia, Ribeiro Pessanha Carolina, Teles Boaventura Gilson
    Abstract:

    Abstract Objective This study evaluated effects of Flaxseed Flour diet on bone health in adult Wistar male rats at 180 d. Methods After birth, pups were randomly assigned: Control (C, n = 12) and Flaxseed Flour (FF, n = 12) diet during lactation period. At 21 d, pups were weaned and they continued to receive the control and experimental diet, respectively. At 180 d, body length, total bone structure, and femur and lumbar vertebrae were evaluated by dual-energy X-ray absorptiometry. Femoral and lumbar vertebra dimensions, biomechanical properties of femur, and serum osteocalcin were measured. Results FF produced greater (P  Conclusion This experimental study found that a diet containing Flaxseed Flour contributed to bone mineral density and femur resistance at 180 d.

  • Effects of Flour or Flaxseed oil upon testis mass in rats subjected to early weaning.
    Natural Product Research, 2017
    Co-Authors: Carlos Alberto Soares Da Costa, Carolina Ribeiro Pessanha, Bianca Ferolla Da Camara Boueri, Gilson Teles Boaventura
    Abstract:

    Study evaluates testis mass in rats subjected to early weaning and subsequently nourished with diet containing Flour or Flaxseed oil. Pups were weaned for separation from mothers at 14 days (early weaning, EW) and 21 days (control, C). After 21 days, the control group (C60) was nourished with control diet. EW was divided as: control (EWC60), Flaxseed Flour (EWFF60) and Flaxseed oil (EWFO60) group diets for the next 60 days. At 21st and 60th day, body mass, serum cholesterol and triglycerides and testis mass were evaluated. At 21 day, EW group showed lower (p 

  • body adiposity and bone parameters of male rats from mothers fed diet containing Flaxseed Flour during lactation
    Journal of Developmental Origins of Health and Disease, 2016
    Co-Authors: C A S Da Costa, Danielle Cavalcante Ribeiro, Paula Cristina Alves Da Silva, A Pereira, Analia Santos, Ligia De Albuquerque Maia, Leandro Dias Ruffoni, F C De Santana, M D C De Abreu, Bianca Ferolla Da Camara Boueri
    Abstract:

    Obesity and osteoporosis may have their origins in early postnatal life. This study was designed to evaluate whether Flaxseed Flour use during lactation period bears effect on body adiposity and skeletal structure of male rat pups at weaning. At birth, male Wistar rats were randomly assigned to control and experimental (FF) groups, whose dams were treated with control or Flaxseed Flour diet, respectively, during lactation. At 21 days of age, pups were weaned to assess body mass, length and composition by dual-energy X-ray absorptiometry. The animals were then sacrificed to carry out analysis of serum profile, intra-abdominal adipocyte morphology and femur characteristics. Differences were considered significant when P<0.05. The FF group displayed the following characteristics (P<0.05): higher body mass, length, bone mineral content, bone area and concentrations of osteoprotegerin, osteocalcin and high-density lipoprotein cholesterol; higher levels of stearic, α-linolenic, eicosapentaenoic and docosapentaenoic acids and lower levels of arachidonic acid and cholesterol; smaller adipocyte area; and higher mass, epiphysis distance, diaphysis width, maximal load, break load, resilience and stiffness of femur. Flaxseed Flour intake during lactation period promoted adipocyte hypertrophy down-regulation and contributed to pup bone quality at weaning.

  • Flaxseed Flour, compared to Flaxseed oil, contributes to femoral structure in male rats subjected to early weaning
    Food & Function, 2016
    Co-Authors: Carolina Ribeiro Pessanha, Bianca Ferolla Da Camara Boueri, Luanna Rodrigues Da Costa, Maitê Rocha Ferreira, Maíra Duque Coutinho De Abreu, Letícia Rozeno Pessoa, Aline D’avila Pereira, Danielle Cavalcante Ribeiro, Eduardo Moreira Da Silva, Carlos Alberto Soares Da Costa
    Abstract:

    The aim of this study was to analyze whether Flaxseed Flour or Flaxseed oil treatment contributes to femoral structure in male rats subjected to early weaning. Pups were weaned for separation from mothers at 14 days (early weaning, EW) or 21 days (control, C). After 21 days, the control (C60) was fed with the control diet. The EW group was divided based on control (EWC60), Flaxseed Flour (EWFF60) and Flaxseed oil (EWFO60) diets until 60 days. Femoral dimension, bone mineral density (BMD), bone mineral content (BMC), area and biomechanical properties were determined. EWFO60 showed lower (P < 0.05) femur mass. EWC60 and EWFO60 showed lower (P < 0.05) distance between epiphyses, diaphysis width and BMD. BMC was lower (P < 0.05) in EWC60 (vs. C60 and EWFF60). EWC60 and EWFO60 showed lower (P < 0.05) maximum force (vs. C60). Breaking strength was lower (P < 0.05) in EWFO60 (vs. C60). EWFF60 showed higher (P < 0.05) rigidity. Flaxseed Flour abbreviated the femoral fragility secondary to early weaning.

Danielle Cavalcante Ribeiro - One of the best experts on this subject based on the ideXlab platform.

  • Flaxseed (linum usitatissimum) Flour contributes to bone health in adult male rats
    Nutrition (Burbank Los Angeles County Calif.), 2017
    Co-Authors: Duque Coutinho De Abreu Maíra, Bianca Ferolla Da Camara Boueri, Luanna Rodrigues Da Costa, Aline D’avila Pereira, Danielle Cavalcante Ribeiro, Eduardo Moreira Da Silva, Carlos Alberto Soares Da Costa, Rozeno Pessoa Letícia, Ribeiro Pessanha Carolina, Teles Boaventura Gilson
    Abstract:

    Abstract Objective This study evaluated effects of Flaxseed Flour diet on bone health in adult Wistar male rats at 180 d. Methods After birth, pups were randomly assigned: Control (C, n = 12) and Flaxseed Flour (FF, n = 12) diet during lactation period. At 21 d, pups were weaned and they continued to receive the control and experimental diet, respectively. At 180 d, body length, total bone structure, and femur and lumbar vertebrae were evaluated by dual-energy X-ray absorptiometry. Femoral and lumbar vertebra dimensions, biomechanical properties of femur, and serum osteocalcin were measured. Results FF produced greater (P  Conclusion This experimental study found that a diet containing Flaxseed Flour contributed to bone mineral density and femur resistance at 180 d.

  • Incorporation of Flaxseed Flour as a Dietary Source for ALA Increases Bone Density and Strength in Post-Partum Female Rats
    Lipids, 2017
    Co-Authors: Danielle Cavalcante Ribeiro, Aline D’avila Pereira, Eduardo Moreira Da Silva, Carlos Alberto Soares Da Costa, Fernanda Carvalho De Santana, Jorge Mancini-filho, Gilson Teles Boaventura
    Abstract:

    In women, bone mass undergoes changes during pregnancy and the postpartum period, which has a risk for subsequent development of osteoporosis. Thus, the present study aims to evaluate the effects of Flaxseed Flour in femur quality during post-weaning of dam rats. After weaning, the rats were divided into control ( C , n  = 7) and experimental ( F , n  = 7) groups treated with a diet containing 25 g of Flaxseed Flour in the lactating period and 15 g in the maintenance period. After 51 days post-partum, serum hormone, fatty acids composition, bone compartments, computed tomography, and biomechanical analyses were determined. Food intake, length, body mass, hormone analysis, and total bone compartments showed similar results. For biomechanical and computed tomography analysis and fatty acids composition, the F group showed higher maximum force (+12%, p  

  • Incorporation of Flaxseed Flour as a Dietary Source for ALA Increases Bone Density and Strength in Post-Partum Female Rats
    Lipids, 2017
    Co-Authors: Danielle Cavalcante Ribeiro, Aline D’avila Pereira, Eduardo Moreira Da Silva, Carlos Alberto Soares Da Costa, Fernanda Carvalho De Santana, Jorge Mancini-filho, Gilson Teles Boaventura
    Abstract:

    In women, bone mass undergoes changes during pregnancy and the postpartum period, which has a risk for subsequent development of osteoporosis. Thus, the present study aims to evaluate the effects of Flaxseed Flour in femur quality during post-weaning of dam rats. After weaning, the rats were divided into control (C, n = 7) and experimental (F, n = 7) groups treated with a diet containing 25 g of Flaxseed Flour in the lactating period and 15 g in the maintenance period. After 51 days post-partum, serum hormone, fatty acids composition, bone compartments, computed tomography, and biomechanical analyses were determined. Food intake, length, body mass, hormone analysis, and total bone compartments showed similar results. For biomechanical and computed tomography analysis and fatty acids composition, the F group showed higher maximum force (+12%, p < 0.05), breaking strength (+25%, p < 0.05), rigidity (+17%, p < 0.0001), and femoral head radiodensity (+15%, p < 0.05) and presented lower total polyunsaturated fatty acids (−17%, p < 0.0001) and arachidonic acid (−44%, p < 0.0001) and higher ALA (+695%, p < 0.0001) and EPA (+160%, p < 0.05). Fatty acids composition of Flaxseed Flour, as well as its protein profile and calcium content, were able to improve the bone quality, which may be associated with lower serum levels of arachidonic acid and higher EPA, showing an anti-inflammatory profile and increased deposition of organic matrix during the post-weaning period, and may result in prevention of future osteoporosis.

  • body adiposity and bone parameters of male rats from mothers fed diet containing Flaxseed Flour during lactation
    Journal of Developmental Origins of Health and Disease, 2016
    Co-Authors: C A S Da Costa, Danielle Cavalcante Ribeiro, Paula Cristina Alves Da Silva, A Pereira, Analia Santos, Ligia De Albuquerque Maia, Leandro Dias Ruffoni, F C De Santana, M D C De Abreu, Bianca Ferolla Da Camara Boueri
    Abstract:

    Obesity and osteoporosis may have their origins in early postnatal life. This study was designed to evaluate whether Flaxseed Flour use during lactation period bears effect on body adiposity and skeletal structure of male rat pups at weaning. At birth, male Wistar rats were randomly assigned to control and experimental (FF) groups, whose dams were treated with control or Flaxseed Flour diet, respectively, during lactation. At 21 days of age, pups were weaned to assess body mass, length and composition by dual-energy X-ray absorptiometry. The animals were then sacrificed to carry out analysis of serum profile, intra-abdominal adipocyte morphology and femur characteristics. Differences were considered significant when P<0.05. The FF group displayed the following characteristics (P<0.05): higher body mass, length, bone mineral content, bone area and concentrations of osteoprotegerin, osteocalcin and high-density lipoprotein cholesterol; higher levels of stearic, α-linolenic, eicosapentaenoic and docosapentaenoic acids and lower levels of arachidonic acid and cholesterol; smaller adipocyte area; and higher mass, epiphysis distance, diaphysis width, maximal load, break load, resilience and stiffness of femur. Flaxseed Flour intake during lactation period promoted adipocyte hypertrophy down-regulation and contributed to pup bone quality at weaning.

  • Flaxseed Flour, compared to Flaxseed oil, contributes to femoral structure in male rats subjected to early weaning
    Food & Function, 2016
    Co-Authors: Carolina Ribeiro Pessanha, Bianca Ferolla Da Camara Boueri, Luanna Rodrigues Da Costa, Maitê Rocha Ferreira, Maíra Duque Coutinho De Abreu, Letícia Rozeno Pessoa, Aline D’avila Pereira, Danielle Cavalcante Ribeiro, Eduardo Moreira Da Silva, Carlos Alberto Soares Da Costa
    Abstract:

    The aim of this study was to analyze whether Flaxseed Flour or Flaxseed oil treatment contributes to femoral structure in male rats subjected to early weaning. Pups were weaned for separation from mothers at 14 days (early weaning, EW) or 21 days (control, C). After 21 days, the control (C60) was fed with the control diet. The EW group was divided based on control (EWC60), Flaxseed Flour (EWFF60) and Flaxseed oil (EWFO60) diets until 60 days. Femoral dimension, bone mineral density (BMD), bone mineral content (BMC), area and biomechanical properties were determined. EWFO60 showed lower (P < 0.05) femur mass. EWC60 and EWFO60 showed lower (P < 0.05) distance between epiphyses, diaphysis width and BMD. BMC was lower (P < 0.05) in EWC60 (vs. C60 and EWFF60). EWC60 and EWFO60 showed lower (P < 0.05) maximum force (vs. C60). Breaking strength was lower (P < 0.05) in EWFO60 (vs. C60). EWFF60 showed higher (P < 0.05) rigidity. Flaxseed Flour abbreviated the femoral fragility secondary to early weaning.