The Experts below are selected from a list of 6 Experts worldwide ranked by ideXlab platform

Sumitro, Sutiman B. - One of the best experts on this subject based on the ideXlab platform.

  • Histopathologic profile grading of haematoxylene eosin on retinoblastoma stadium
    Airlangga University Press, 2011
    Co-Authors: Soebagjo, Hendrian Dwikoloso, Hoesin Farouk, Notobroto, Hari Basuki, Sumitro, Sutiman B.
    Abstract:

    The purpose of this study was to investigate the morphological features of retinoblastoma with histopathologic aggressiveness on retinoblastoma patients. Retrospective reviewed and analyzed was done according Spearman correlation method. Fiveteen retinoblastoma patients surgical eye specimens were collected and examined at pathology laboratory of Dr. Soetomo Hospital between January 1st, to December 31st, 2010. The patients age average was 47.73 months ± 28.23 months, consist of 60% (9) male and 40% (6) female patients with 93.3% (14) unilateral and 6.7% (1) bilateral. The clinical phenomenas are leucokoria 100% (15), proptosis and chemosis 86.7% (13), optic nerve invasion 50% (6), muscles extraocular invasion 20% (3). exenteration 13 (86.7%), and enucleation 2 (13.3%) . The histopathological features indicated that Rosette cells has been more observed on Flexner-Wintersteiner Rosette 73.3% (11), along with pleomorphic cell 60% (9), necrotic cell 33.3% (5) as well as mitotic cells 60% (9). The tumors usually are poor differentiated 8 (53.3%). Retinoblastoma International Staging was not significanly in association to the tumor differentiation/histopatologicalgrading (rs = -0.170, p = 0.545). However, this study realized that a correlation between the differentiation of retinoblastoma tumor cells with histopathological grading namely in term of the pleumorphic, necrotic and mitotic cell population (α

Soebagjo, Hendrian Dwikoloso - One of the best experts on this subject based on the ideXlab platform.

  • Histopathologic profile grading of haematoxylene eosin on retinoblastoma stadium
    Airlangga University Press, 2011
    Co-Authors: Soebagjo, Hendrian Dwikoloso, Hoesin Farouk, Notobroto, Hari Basuki, Sumitro, Sutiman B.
    Abstract:

    The purpose of this study was to investigate the morphological features of retinoblastoma with histopathologic aggressiveness on retinoblastoma patients. Retrospective reviewed and analyzed was done according Spearman correlation method. Fiveteen retinoblastoma patients surgical eye specimens were collected and examined at pathology laboratory of Dr. Soetomo Hospital between January 1st, to December 31st, 2010. The patients age average was 47.73 months ± 28.23 months, consist of 60% (9) male and 40% (6) female patients with 93.3% (14) unilateral and 6.7% (1) bilateral. The clinical phenomenas are leucokoria 100% (15), proptosis and chemosis 86.7% (13), optic nerve invasion 50% (6), muscles extraocular invasion 20% (3). exenteration 13 (86.7%), and enucleation 2 (13.3%) . The histopathological features indicated that Rosette cells has been more observed on Flexner-Wintersteiner Rosette 73.3% (11), along with pleomorphic cell 60% (9), necrotic cell 33.3% (5) as well as mitotic cells 60% (9). The tumors usually are poor differentiated 8 (53.3%). Retinoblastoma International Staging was not significanly in association to the tumor differentiation/histopatologicalgrading (rs = -0.170, p = 0.545). However, this study realized that a correlation between the differentiation of retinoblastoma tumor cells with histopathological grading namely in term of the pleumorphic, necrotic and mitotic cell population (α

Hoesin Farouk - One of the best experts on this subject based on the ideXlab platform.

  • Histopathologic profile grading of haematoxylene eosin on retinoblastoma stadium
    Airlangga University Press, 2011
    Co-Authors: Soebagjo, Hendrian Dwikoloso, Hoesin Farouk, Notobroto, Hari Basuki, Sumitro, Sutiman B.
    Abstract:

    The purpose of this study was to investigate the morphological features of retinoblastoma with histopathologic aggressiveness on retinoblastoma patients. Retrospective reviewed and analyzed was done according Spearman correlation method. Fiveteen retinoblastoma patients surgical eye specimens were collected and examined at pathology laboratory of Dr. Soetomo Hospital between January 1st, to December 31st, 2010. The patients age average was 47.73 months ± 28.23 months, consist of 60% (9) male and 40% (6) female patients with 93.3% (14) unilateral and 6.7% (1) bilateral. The clinical phenomenas are leucokoria 100% (15), proptosis and chemosis 86.7% (13), optic nerve invasion 50% (6), muscles extraocular invasion 20% (3). exenteration 13 (86.7%), and enucleation 2 (13.3%) . The histopathological features indicated that Rosette cells has been more observed on Flexner-Wintersteiner Rosette 73.3% (11), along with pleomorphic cell 60% (9), necrotic cell 33.3% (5) as well as mitotic cells 60% (9). The tumors usually are poor differentiated 8 (53.3%). Retinoblastoma International Staging was not significanly in association to the tumor differentiation/histopatologicalgrading (rs = -0.170, p = 0.545). However, this study realized that a correlation between the differentiation of retinoblastoma tumor cells with histopathological grading namely in term of the pleumorphic, necrotic and mitotic cell population (α

Notobroto, Hari Basuki - One of the best experts on this subject based on the ideXlab platform.

  • Histopathologic profile grading of haematoxylene eosin on retinoblastoma stadium
    Airlangga University Press, 2011
    Co-Authors: Soebagjo, Hendrian Dwikoloso, Hoesin Farouk, Notobroto, Hari Basuki, Sumitro, Sutiman B.
    Abstract:

    The purpose of this study was to investigate the morphological features of retinoblastoma with histopathologic aggressiveness on retinoblastoma patients. Retrospective reviewed and analyzed was done according Spearman correlation method. Fiveteen retinoblastoma patients surgical eye specimens were collected and examined at pathology laboratory of Dr. Soetomo Hospital between January 1st, to December 31st, 2010. The patients age average was 47.73 months ± 28.23 months, consist of 60% (9) male and 40% (6) female patients with 93.3% (14) unilateral and 6.7% (1) bilateral. The clinical phenomenas are leucokoria 100% (15), proptosis and chemosis 86.7% (13), optic nerve invasion 50% (6), muscles extraocular invasion 20% (3). exenteration 13 (86.7%), and enucleation 2 (13.3%) . The histopathological features indicated that Rosette cells has been more observed on Flexner-Wintersteiner Rosette 73.3% (11), along with pleomorphic cell 60% (9), necrotic cell 33.3% (5) as well as mitotic cells 60% (9). The tumors usually are poor differentiated 8 (53.3%). Retinoblastoma International Staging was not significanly in association to the tumor differentiation/histopatologicalgrading (rs = -0.170, p = 0.545). However, this study realized that a correlation between the differentiation of retinoblastoma tumor cells with histopathological grading namely in term of the pleumorphic, necrotic and mitotic cell population (α

Ana Krvavica - One of the best experts on this subject based on the ideXlab platform.

  • Neuroendocrine carcinoma of the posterior mediastinum - a case report
    General hospital Zadar, 2008
    Co-Authors: Ana Krvavica
    Abstract:

    Prikazan je slucaj 64-godišnjeg bolesnika s tumorom stražnjeg gornjeg medijastinuma uz racvište dušnika. Mikroskopski, tumor je graden od angiocentricno poredanih otoka stanica koje su na periferiji visoke, cilindricne, te stvaraju Flexner-Wintersteiner rosete i palisade, dok su u središtu poligonalne, s bizarnim multilobuliranim oblicima jezgri, visokom mitotickom aktivnošcu i znatnom nekrozom. Grimelius metodom dokazana su argentafilna tjelešca u jezgri. Imunohistokemijski, tumorske stanice su izrazito pozitivne na epitelne i neuroendokrine markere EMA, Cytokeratin MNF-116, NSE, S-100 i Chromogranin-A, dok su CD-99, TTF-1, Vimentin i p-21 negativne. Obzirom na opisanu histološku sliku, tumor je dijagnosticiran kao rijetki primarni neuroendokrini karcinom velikih stanica smješten u stražnjem gornjem medijastinumu.A tumor mass was noted in the posterior mediastinum on the tracheal bifurcation in a 64-year- old man. Microscopically the tumor consisted of angiocentric atypical cylindrical epithelial cells that often form Flexner-Wintersteiner Rosette and palisade. In the centre of the tumor island the cells were polygonal and showed bizzare multinucleated nuclei with marked necrosis and mitotic activity. The argentafillic bodies were identified by the Grimelius method. Immunohistochemically, the tumor cells expressed both epithelial and neuroendocrine markers, including Cytokeratin MNF-116, EMA, NSE, S-100, Synaptophysin and Chromogranin A; while CD-99, TTF-1, Vimentin, p-21 were negative. The described tumor was diagnosed as a rare, primary neuroendocrine carcinoma of large cells in the upper posterior me