The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Laurence S Baskin - One of the best experts on this subject based on the ideXlab platform.
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novel measurement tool and model for aberrant urinary stream in 3d printed urethras derived from human tissue
PLOS ONE, 2020Co-Authors: Andrew J Cohen, German Patino, Mehran Mirramezani, Sudarshan Srirangapatanam, Anas Tresh, Bhagat Cheema, Jenny Tai, Dylan Romero, Anthony Enriquez, Laurence S BaskinAbstract:BACKGROUND An estimated 10% of male adults have split or dribbled stream leading to poor hygiene, embarrassment, and inconvenience. There is no current metric that measures male stream deviation. OBJECTIVE To develop a novel method to measure spray in normal and abnormal anatomical conformations. DESIGN, SETTING, AND PARTICIPANTS We developed a novel platform to reliably describe spray. We used cadaveric tissues and 3D Printed models to study the impact of meatal shape on the urinary stream. Cadaveric penile tissue and 3D printed models were affixed to a fluid pump and used to simulate micturition. Dye captured on fabric allowed for spray detection. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS Spray pattern area, deviation from normal location, and Flowrates were recorded. Computational fluid dynamic models were created to study fluid vorticity. RESULTS AND LIMITATIONS Obstructions at the penile tip worsened spray dynamics and reduced flow. Ventral meatotomy improved flowrate (p<0.05) and reduced spray (p<0.05) compared to tips obstructed ventrally, dorsally or in the fossa navicularis. 3D models do not fully reproduce parameters of their parent cadaver material. The average flowrate from 3D model was 10ml/sec less than that of the penis from which it was derived (p = 0.03). Nonetheless, as in cadavers, increasing obstruction in 3D models leads to the same pattern of reduced flowrate and worse spray. Dynamic modeling revealed increasing distal obstruction was correlated to higher relative vorticity observed at the urethral tip. CONCLUSIONS We developed a robust method to measure urine spray in a research setting. Dynamic 3D printed models hold promise as a methodology to study common pathologies in the urethra and corrective surgeries on the urine stream that would not be feasible in patients. These novel methods require further validation, but offer promise as a research and clinical tool.
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novel measurement tool and model for aberrant urinary stream in 3d printed urethras derived from human tissue
PLOS ONE, 2020Co-Authors: Andrew J Cohen, German Patino, Mehran Mirramezani, Sudarshan Srirangapatanam, Anas Tresh, Bhagat Cheema, Jenny Tai, Dylan Romero, Anthony Enriquez, Laurence S BaskinAbstract:Author(s): Cohen, Andrew J; Patino, German; Mirramezani, Mehran; Srirangapatanam, Sudarshan; Tresh, Anas; Cheema, Bhagat; Tai, Jenny; Romero, Dylan; Enriquez, Anthony; Baskin, Laurence S; Shadden, Shawn C; Breyer, Benjamin N | Abstract: BackgroundAn estimated 10% of male adults have split or dribbled stream leading to poor hygiene, embarrassment, and inconvenience. There is no current metric that measures male stream deviation.ObjectiveTo develop a novel method to measure spray in normal and abnormal anatomical conformations.Design, setting, and participantsWe developed a novel platform to reliably describe spray. We used cadaveric tissues and 3D Printed models to study the impact of meatal shape on the urinary stream. Cadaveric penile tissue and 3D printed models were affixed to a fluid pump and used to simulate micturition. Dye captured on fabric allowed for spray detection.Outcome measurements and statistical analysisSpray pattern area, deviation from normal location, and Flowrates were recorded. Computational fluid dynamic models were created to study fluid vorticity.Results and limitationsObstructions at the penile tip worsened spray dynamics and reduced flow. Ventral meatotomy improved flowrate (pl0.05) and reduced spray (pl0.05) compared to tips obstructed ventrally, dorsally or in the fossa navicularis. 3D models do not fully reproduce parameters of their parent cadaver material. The average flowrate from 3D model was 10ml/sec less than that of the penis from which it was derived (p = 0.03). Nonetheless, as in cadavers, increasing obstruction in 3D models leads to the same pattern of reduced flowrate and worse spray. Dynamic modeling revealed increasing distal obstruction was correlated to higher relative vorticity observed at the urethral tip.ConclusionsWe developed a robust method to measure urine spray in a research setting. Dynamic 3D printed models hold promise as a methodology to study common pathologies in the urethra and corrective surgeries on the urine stream that would not be feasible in patients. These novel methods require further validation, but offer promise as a research and clinical tool.
Andrew J Cohen - One of the best experts on this subject based on the ideXlab platform.
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novel measurement tool and model for aberrant urinary stream in 3d printed urethras derived from human tissue
PLOS ONE, 2020Co-Authors: Andrew J Cohen, German Patino, Mehran Mirramezani, Sudarshan Srirangapatanam, Anas Tresh, Bhagat Cheema, Jenny Tai, Dylan Romero, Anthony Enriquez, Laurence S BaskinAbstract:BACKGROUND An estimated 10% of male adults have split or dribbled stream leading to poor hygiene, embarrassment, and inconvenience. There is no current metric that measures male stream deviation. OBJECTIVE To develop a novel method to measure spray in normal and abnormal anatomical conformations. DESIGN, SETTING, AND PARTICIPANTS We developed a novel platform to reliably describe spray. We used cadaveric tissues and 3D Printed models to study the impact of meatal shape on the urinary stream. Cadaveric penile tissue and 3D printed models were affixed to a fluid pump and used to simulate micturition. Dye captured on fabric allowed for spray detection. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS Spray pattern area, deviation from normal location, and Flowrates were recorded. Computational fluid dynamic models were created to study fluid vorticity. RESULTS AND LIMITATIONS Obstructions at the penile tip worsened spray dynamics and reduced flow. Ventral meatotomy improved flowrate (p<0.05) and reduced spray (p<0.05) compared to tips obstructed ventrally, dorsally or in the fossa navicularis. 3D models do not fully reproduce parameters of their parent cadaver material. The average flowrate from 3D model was 10ml/sec less than that of the penis from which it was derived (p = 0.03). Nonetheless, as in cadavers, increasing obstruction in 3D models leads to the same pattern of reduced flowrate and worse spray. Dynamic modeling revealed increasing distal obstruction was correlated to higher relative vorticity observed at the urethral tip. CONCLUSIONS We developed a robust method to measure urine spray in a research setting. Dynamic 3D printed models hold promise as a methodology to study common pathologies in the urethra and corrective surgeries on the urine stream that would not be feasible in patients. These novel methods require further validation, but offer promise as a research and clinical tool.
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novel measurement tool and model for aberrant urinary stream in 3d printed urethras derived from human tissue
PLOS ONE, 2020Co-Authors: Andrew J Cohen, German Patino, Mehran Mirramezani, Sudarshan Srirangapatanam, Anas Tresh, Bhagat Cheema, Jenny Tai, Dylan Romero, Anthony Enriquez, Laurence S BaskinAbstract:Author(s): Cohen, Andrew J; Patino, German; Mirramezani, Mehran; Srirangapatanam, Sudarshan; Tresh, Anas; Cheema, Bhagat; Tai, Jenny; Romero, Dylan; Enriquez, Anthony; Baskin, Laurence S; Shadden, Shawn C; Breyer, Benjamin N | Abstract: BackgroundAn estimated 10% of male adults have split or dribbled stream leading to poor hygiene, embarrassment, and inconvenience. There is no current metric that measures male stream deviation.ObjectiveTo develop a novel method to measure spray in normal and abnormal anatomical conformations.Design, setting, and participantsWe developed a novel platform to reliably describe spray. We used cadaveric tissues and 3D Printed models to study the impact of meatal shape on the urinary stream. Cadaveric penile tissue and 3D printed models were affixed to a fluid pump and used to simulate micturition. Dye captured on fabric allowed for spray detection.Outcome measurements and statistical analysisSpray pattern area, deviation from normal location, and Flowrates were recorded. Computational fluid dynamic models were created to study fluid vorticity.Results and limitationsObstructions at the penile tip worsened spray dynamics and reduced flow. Ventral meatotomy improved flowrate (pl0.05) and reduced spray (pl0.05) compared to tips obstructed ventrally, dorsally or in the fossa navicularis. 3D models do not fully reproduce parameters of their parent cadaver material. The average flowrate from 3D model was 10ml/sec less than that of the penis from which it was derived (p = 0.03). Nonetheless, as in cadavers, increasing obstruction in 3D models leads to the same pattern of reduced flowrate and worse spray. Dynamic modeling revealed increasing distal obstruction was correlated to higher relative vorticity observed at the urethral tip.ConclusionsWe developed a robust method to measure urine spray in a research setting. Dynamic 3D printed models hold promise as a methodology to study common pathologies in the urethra and corrective surgeries on the urine stream that would not be feasible in patients. These novel methods require further validation, but offer promise as a research and clinical tool.
Lingai Luo - One of the best experts on this subject based on the ideXlab platform.
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multi channel heat exchanger reactor using arborescent distributors a characterization study of fluid distribution heat exchange performance and exothermic reaction
Energy, 2014Co-Authors: Xiaofeng Guo, Lingai LuoAbstract:A multi-functional heat exchanger-reactor comprising arborescent (tree-like) distributors and collector, 16 mini-channels in parallel and T-mixers is introduced in this paper. Flow distribution property, pressure drop and heat exchange performance of proposed heat exchanger-reactor are tested and discussed. Firstly, flow distribution uniformity is characterized by CFD simulation and then qualitatively confirmed by visualization experiment. Results show that for total Flowrates ranging from 5 mL s−1 to 20 mL s−1, good distribution uniformity is obtained, with maximum flowrate deviation less than 10%. Then, experiments of heat exchange between hot and cold water are carried out. High values of overall heat transfer coefficient ranging from 2000 to 5000 W m−2 °C−1 are obtained under our working conditions. The volumetric heat exchange capability (UA/V) is found to be around 200 kW m−3 °C−1, showing a high heat exchange capability with compact design. The roles of end-effect and non-established flow are discussed and are supposed to be responsible for efficient heat transfer. Finally a typical fast exothermic reaction, neutralization between acid and basic solutions, is carried out to test the thermal control capability of the studied heat exchanger-reactor. Results indicate that isothermal condition could be realized by circulating appropriate flowrate of coolant through the heat exchanger.
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Multi-channel heat exchanger-reactor using arborescent distributors: A characterization study of fluid distribution, heat exchange performance and exothermic reaction
Energy, 2014Co-Authors: Xiaofeng Guo, Yilin Fan, Lingai LuoAbstract:Abstract A multi-functional heat exchanger-reactor comprising arborescent (tree-like) distributors and collector, 16 mini-channels in parallel and T-mixers is introduced in this paper. Flow distribution property, pressure drop and heat exchange performance of proposed heat exchanger-reactor are tested and discussed. Firstly, flow distribution uniformity is characterized by CFD simulation and then qualitatively confirmed by visualization experiment. Results show that for total Flowrates ranging from 5 mL s −1 to 20 mL s −1 , good distribution uniformity is obtained, with maximum flowrate deviation less than 10%. Then, experiments of heat exchange between hot and cold water are carried out. High values of overall heat transfer coefficient ranging from 2000 to 5000 W m −2 °C −1 are obtained under our working conditions. The volumetric heat exchange capability ( UA / V ) is found to be around 200 kW m −3 °C −1 , showing a high heat exchange capability with compact design. The roles of end-effect and non-established flow are discussed and are supposed to be responsible for efficient heat transfer. Finally a typical fast exothermic reaction, neutralization between acid and basic solutions, is carried out to test the thermal control capability of the studied heat exchanger-reactor. Results indicate that isothermal condition could be realized by circulating appropriate flowrate of coolant through the heat exchanger. The design of heat exchanger-reactor with arborescent distributor and collector makes possible the application of multi-channel systems. This paper introduces systematically the successful integration of heat exchanger-reactor and its performance evaluation.
Xiaofeng Guo - One of the best experts on this subject based on the ideXlab platform.
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multi channel heat exchanger reactor using arborescent distributors a characterization study of fluid distribution heat exchange performance and exothermic reaction
Energy, 2014Co-Authors: Xiaofeng Guo, Lingai LuoAbstract:A multi-functional heat exchanger-reactor comprising arborescent (tree-like) distributors and collector, 16 mini-channels in parallel and T-mixers is introduced in this paper. Flow distribution property, pressure drop and heat exchange performance of proposed heat exchanger-reactor are tested and discussed. Firstly, flow distribution uniformity is characterized by CFD simulation and then qualitatively confirmed by visualization experiment. Results show that for total Flowrates ranging from 5 mL s−1 to 20 mL s−1, good distribution uniformity is obtained, with maximum flowrate deviation less than 10%. Then, experiments of heat exchange between hot and cold water are carried out. High values of overall heat transfer coefficient ranging from 2000 to 5000 W m−2 °C−1 are obtained under our working conditions. The volumetric heat exchange capability (UA/V) is found to be around 200 kW m−3 °C−1, showing a high heat exchange capability with compact design. The roles of end-effect and non-established flow are discussed and are supposed to be responsible for efficient heat transfer. Finally a typical fast exothermic reaction, neutralization between acid and basic solutions, is carried out to test the thermal control capability of the studied heat exchanger-reactor. Results indicate that isothermal condition could be realized by circulating appropriate flowrate of coolant through the heat exchanger.
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Multi-channel heat exchanger-reactor using arborescent distributors: A characterization study of fluid distribution, heat exchange performance and exothermic reaction
Energy, 2014Co-Authors: Xiaofeng Guo, Yilin Fan, Lingai LuoAbstract:Abstract A multi-functional heat exchanger-reactor comprising arborescent (tree-like) distributors and collector, 16 mini-channels in parallel and T-mixers is introduced in this paper. Flow distribution property, pressure drop and heat exchange performance of proposed heat exchanger-reactor are tested and discussed. Firstly, flow distribution uniformity is characterized by CFD simulation and then qualitatively confirmed by visualization experiment. Results show that for total Flowrates ranging from 5 mL s −1 to 20 mL s −1 , good distribution uniformity is obtained, with maximum flowrate deviation less than 10%. Then, experiments of heat exchange between hot and cold water are carried out. High values of overall heat transfer coefficient ranging from 2000 to 5000 W m −2 °C −1 are obtained under our working conditions. The volumetric heat exchange capability ( UA / V ) is found to be around 200 kW m −3 °C −1 , showing a high heat exchange capability with compact design. The roles of end-effect and non-established flow are discussed and are supposed to be responsible for efficient heat transfer. Finally a typical fast exothermic reaction, neutralization between acid and basic solutions, is carried out to test the thermal control capability of the studied heat exchanger-reactor. Results indicate that isothermal condition could be realized by circulating appropriate flowrate of coolant through the heat exchanger. The design of heat exchanger-reactor with arborescent distributor and collector makes possible the application of multi-channel systems. This paper introduces systematically the successful integration of heat exchanger-reactor and its performance evaluation.
Lijuan Wang - One of the best experts on this subject based on the ideXlab platform.
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mass flow measurement of gas liquid two phase co2 in ccs transportation pipelines using coriolis flowmeters
International Journal of Greenhouse Gas Control, 2018Co-Authors: Quansheng Duan, Lijuan Wang, Xue Wang, Tao Wang, Wenbiao ZhangAbstract:Abstract Carbon Capture and Storage (CCS) is a promising technology that stops the release of CO2 from industrial processes such as electrical power generation. Accurate measurement of CO2 flows in a CCS system where CO2 flow is a gas, liquid, or gas-liquid two-phase mixture is essential for the fiscal purpose and potential leakage detection. This paper presents a novel method based on Coriolis mass flowmeters in conjunction with least squares support vector machine (LSSVM) models to measure gas-liquid two-phase CO2 flow under CCS conditions. The method uses a classifier to identify the flow pattern and individual LSSVM models for the metering of CO2 mass flowrate and prediction of gas volume fraction of CO2, respectively. Experimental work was undertaken on a multiphase CO2 flow test facility. Performance comparisons between the general LSSVM and flow pattern based LSSVM models are conducted. Results demonstrate that Coriolis mass flowmeters with the LSSVM model incorporating flow pattern identification algorithms perform significantly better than those using the general LSSVM model. The mass flowrate measurement of gas-liquid CO2 is found to yield errors less than ±2% on the horizontal pipeline and ±1.5% on the vertical pipeline, respectively, over Flowrates from 250 kg/h to 3200 kg/h. The error in the estimation of CO2 gas volume fraction is within ±10% over the same range of flow rates.