The Experts below are selected from a list of 19305 Experts worldwide ranked by ideXlab platform
Antonella Di Sotto - One of the best experts on this subject based on the ideXlab platform.
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Staphylococcus lugdunensis: a neglected pathogen of infections involving Fracture-Fixation devices
International Orthopaedics, 2017Co-Authors: Piseth Seng, Madou Traore, Laurence Maulin, Jeanfrancois Thiery, Pierreyves Levy, Pierremarie Roger, E Bonnet, Jean-christophe Lagier, Jean-philippe Lavigne, Antonella Di SottoAbstract:Purpose Cases of Fracture-Fixation device infection involving Staphylococcus lugdunensis are not frequent. The clinical characteristics and the choice of treatment strategies of these infections are not obviously known to date. Methods We performed a review of Fracture-Fixation device infection involving S. lugdunensis managed by our centres. Results Among the 38 cases of Fracture-Fixation device infection involving S. lugdunensis , 53% were located in the tibia. Most of our cases (87%) were chronic infections. Purulent discharge, which occurred in 79% of cases, was the most frequent clinical symptom, followed by pain in 63%, local inflammation in 55%, and fever in 37%. Bacteremia and severe sepsis occurred in 10% and 18% of cases, respectively. Four cases (10%) were treated exclusively with antimicrobial treatment alone. Thirty-four cases (89%) were treated with a combination of surgery with antimicrobial therapy including surgical debridement, antibiotics and osteosynthesis device retention in six cases (16%), and osteosynthesis device removal in 27 cases (71%). The mean length of antibiotic treatment was 119 days. The relapse rate was high that was not related to selection of resistant strains. Polymicrobial infection had no impact on clinical outcome. A combination of surgery with antimicrobial therapy was identified as a significant prognostic factor associated with remission ( p = 0.042). Conclusions S. lugdunensis is probably involved in more infections than has been reported. Using appropriate microbiological methods laboratories should routinely identify the species of all coagulase-negative Staphylococci isolates involved in Fracture-Fixation device infection to better achieve the treatment strategies of Fracture-Fixation device infection involving S. lugdunensis .
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staphylococcus lugdunensis a neglected pathogen of infections involving Fracture Fixation devices
International Orthopaedics, 2017Co-Authors: Piseth Seng, Madou Traore, Laurence Maulin, Jeanfrancois Thiery, Pierreyves Levy, Pierremarie Roger, E Bonnet, Jean-christophe Lagier, Jean-philippe Lavigne, Antonella Di SottoAbstract:Purpose Cases of Fracture-Fixation device infection involving Staphylococcus lugdunensis are not frequent. The clinical characteristics and the choice of treatment strategies of these infections are not obviously known to date.
Piseth Seng - One of the best experts on this subject based on the ideXlab platform.
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Staphylococcus lugdunensis: a neglected pathogen of infections involving Fracture-Fixation devices
International Orthopaedics, 2017Co-Authors: Piseth Seng, Madou Traore, Laurence Maulin, Jeanfrancois Thiery, Pierreyves Levy, Pierremarie Roger, E Bonnet, Jean-christophe Lagier, Jean-philippe Lavigne, Antonella Di SottoAbstract:Purpose Cases of Fracture-Fixation device infection involving Staphylococcus lugdunensis are not frequent. The clinical characteristics and the choice of treatment strategies of these infections are not obviously known to date. Methods We performed a review of Fracture-Fixation device infection involving S. lugdunensis managed by our centres. Results Among the 38 cases of Fracture-Fixation device infection involving S. lugdunensis , 53% were located in the tibia. Most of our cases (87%) were chronic infections. Purulent discharge, which occurred in 79% of cases, was the most frequent clinical symptom, followed by pain in 63%, local inflammation in 55%, and fever in 37%. Bacteremia and severe sepsis occurred in 10% and 18% of cases, respectively. Four cases (10%) were treated exclusively with antimicrobial treatment alone. Thirty-four cases (89%) were treated with a combination of surgery with antimicrobial therapy including surgical debridement, antibiotics and osteosynthesis device retention in six cases (16%), and osteosynthesis device removal in 27 cases (71%). The mean length of antibiotic treatment was 119 days. The relapse rate was high that was not related to selection of resistant strains. Polymicrobial infection had no impact on clinical outcome. A combination of surgery with antimicrobial therapy was identified as a significant prognostic factor associated with remission ( p = 0.042). Conclusions S. lugdunensis is probably involved in more infections than has been reported. Using appropriate microbiological methods laboratories should routinely identify the species of all coagulase-negative Staphylococci isolates involved in Fracture-Fixation device infection to better achieve the treatment strategies of Fracture-Fixation device infection involving S. lugdunensis .
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staphylococcus lugdunensis a neglected pathogen of infections involving Fracture Fixation devices
International Orthopaedics, 2017Co-Authors: Piseth Seng, Madou Traore, Laurence Maulin, Jeanfrancois Thiery, Pierreyves Levy, Pierremarie Roger, E Bonnet, Jean-christophe Lagier, Jean-philippe Lavigne, Antonella Di SottoAbstract:Purpose Cases of Fracture-Fixation device infection involving Staphylococcus lugdunensis are not frequent. The clinical characteristics and the choice of treatment strategies of these infections are not obviously known to date.
A. Vallejo - One of the best experts on this subject based on the ideXlab platform.
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Design-Optimization and Material Selection for a Proximal Radius Fracture-Fixation Implant
Journal of Materials Engineering and Performance, 2010Co-Authors: M. Grujicic, G. Arakere, A. Grujicic, D. W. Wagner, A. VallejoAbstract:The problem of optimal size, shape, and placement of a proximal radius-Fracture Fixation-plate is addressed computationally using a combined finite-element/design-optimization procedure. To expand the set of physiological loading conditions experienced by the implant during normal everyday activities of the patient, beyond those typically covered by the pre-clinical implant-evaluation testing procedures, the case of a wheel-chair push exertion is considered. Toward that end, a musculoskeletal multi-body inverse-dynamics analysis is carried out of a human propelling a wheelchair. The results obtained are used as input to a finite-element structural analysis for evaluation of the maximum stress and fatigue life of the parametrically defined implant design. While optimizing the design of the radius-Fracture Fixation-plate, realistic functional requirements pertaining to the attainment of the required level of the devise safety factor and longevity/lifecycle were considered. It is argued that the type of analyses employed in the present work should be: (a) used to complement the standard experimental pre-clinical implant-evaluation tests (the tests which normally include a limited number of daily-living physiological loading conditions and which rely on single pass/fail outcomes/decisions with respect to a set of lower-bound implant-performance criteria) and (b) integrated early in the implant design and material/manufacturing-route selection process.
Daniel Kendoff - One of the best experts on this subject based on the ideXlab platform.
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high rates of occult infection after shoulder Fracture Fixation considerations for conversion shoulder arthroplasty
HSS Journal, 2015Co-Authors: Till O. Klatte, Reza Sabihi, Daniel Guenther, Atul F. Kamath, Johannes M. Rueger, Thorsten Gehrke, Daniel KendoffAbstract:Background Existing hardware may contribute to increased risk of bacterial contamination and subsequent periprosthetic joint infection (PJI) in conversion shoulder arthroplasty performed for failed Fracture Fixation.
Jeanfrancois Thiery - One of the best experts on this subject based on the ideXlab platform.
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Staphylococcus lugdunensis: a neglected pathogen of infections involving Fracture-Fixation devices
International Orthopaedics, 2017Co-Authors: Piseth Seng, Madou Traore, Laurence Maulin, Jeanfrancois Thiery, Pierreyves Levy, Pierremarie Roger, E Bonnet, Jean-christophe Lagier, Jean-philippe Lavigne, Antonella Di SottoAbstract:Purpose Cases of Fracture-Fixation device infection involving Staphylococcus lugdunensis are not frequent. The clinical characteristics and the choice of treatment strategies of these infections are not obviously known to date. Methods We performed a review of Fracture-Fixation device infection involving S. lugdunensis managed by our centres. Results Among the 38 cases of Fracture-Fixation device infection involving S. lugdunensis , 53% were located in the tibia. Most of our cases (87%) were chronic infections. Purulent discharge, which occurred in 79% of cases, was the most frequent clinical symptom, followed by pain in 63%, local inflammation in 55%, and fever in 37%. Bacteremia and severe sepsis occurred in 10% and 18% of cases, respectively. Four cases (10%) were treated exclusively with antimicrobial treatment alone. Thirty-four cases (89%) were treated with a combination of surgery with antimicrobial therapy including surgical debridement, antibiotics and osteosynthesis device retention in six cases (16%), and osteosynthesis device removal in 27 cases (71%). The mean length of antibiotic treatment was 119 days. The relapse rate was high that was not related to selection of resistant strains. Polymicrobial infection had no impact on clinical outcome. A combination of surgery with antimicrobial therapy was identified as a significant prognostic factor associated with remission ( p = 0.042). Conclusions S. lugdunensis is probably involved in more infections than has been reported. Using appropriate microbiological methods laboratories should routinely identify the species of all coagulase-negative Staphylococci isolates involved in Fracture-Fixation device infection to better achieve the treatment strategies of Fracture-Fixation device infection involving S. lugdunensis .
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staphylococcus lugdunensis a neglected pathogen of infections involving Fracture Fixation devices
International Orthopaedics, 2017Co-Authors: Piseth Seng, Madou Traore, Laurence Maulin, Jeanfrancois Thiery, Pierreyves Levy, Pierremarie Roger, E Bonnet, Jean-christophe Lagier, Jean-philippe Lavigne, Antonella Di SottoAbstract:Purpose Cases of Fracture-Fixation device infection involving Staphylococcus lugdunensis are not frequent. The clinical characteristics and the choice of treatment strategies of these infections are not obviously known to date.
