The Experts below are selected from a list of 5640 Experts worldwide ranked by ideXlab platform
Chune Dong - One of the best experts on this subject based on the ideXlab platform.
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Enhanced efficiency of recyclable C3-symmetric cinchonine-squaramides in the asymmetric Friedel–Crafts Reaction of indoles with alkyl trifluoropyruvate
Tetrahedron-asymmetry, 2012Co-Authors: Xin Han, Hai-bing Zhou, Bin Liu, Chune DongAbstract:Abstract The highly enantioselective Friedel–Crafts Reaction of indoles with trifluoropyruvate catalyzed by a C 3 -symmetric cinchonine-squaramide is reported. A wide variety of trifluoromethylated indole derivatives were obtained in high yields and with excellent enantioselectivities (99% and up to >99% ee). Moreover the C 3 catalyst can be easily recovered and was used five times.
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enhanced efficiency of recyclable c3 symmetric cinchonine squaramides in the asymmetric Friedel Crafts Reaction of indoles with alkyl trifluoropyruvate
Tetrahedron-asymmetry, 2012Co-Authors: Xin Han, Hai-bing Zhou, Bin Liu, Chune DongAbstract:Abstract The highly enantioselective Friedel–Crafts Reaction of indoles with trifluoropyruvate catalyzed by a C 3 -symmetric cinchonine-squaramide is reported. A wide variety of trifluoromethylated indole derivatives were obtained in high yields and with excellent enantioselectivities (99% and up to >99% ee). Moreover the C 3 catalyst can be easily recovered and was used five times.
Wei Wang - One of the best experts on this subject based on the ideXlab platform.
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organocatalytic enantioselective Friedel Crafts Reaction of 1 naphthols with isatins and an unexpected spontaneous dehydration process
ChemInform, 2014Co-Authors: Xuwen Zhang, Yingfei Xue, Wei Wang, Jin ZhuAbstract:The enantioselective Friedel—Crafts Reaction of 1-naphthols with isatins and subsequent treatment of the products with ethyl iodide gives compounds (IV) with good to high enantioselectivities.
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Organocatalytic Enantioselective Friedel—Crafts Reaction of 1‐Naphthols with Isatins and an Unexpected Spontaneous Dehydration Process.
ChemInform, 2014Co-Authors: Xuwen Zhang, Yingfei Xue, Wei Wang, Jin ZhuAbstract:The enantioselective Friedel—Crafts Reaction of 1-naphthols with isatins and subsequent treatment of the products with ethyl iodide gives compounds (IV) with good to high enantioselectivities.
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facile creation of 3 indolyl 3 hydroxy 2 oxindoles by an organocatalytic enantioselective Friedel Crafts Reaction of indoles with isatins
Advanced Synthesis & Catalysis, 2010Co-Authors: Jing Deng, Wei Wang, Shilei Zhang, Peng Ding, Hualiang JiangAbstract:The first direct enantioselective Friedel-Crafts Reaction of indoles with isatins has been developed. The process is catalyzed by simple cupreine under mild Reaction conditions and affords synthetically and biologically interesting, chiral 3-indolyl-3-hydroxy-2-oxindoles in good yields (68-97%) and with high enantioselectivities (76-91%).
Yong-jun Chen - One of the best experts on this subject based on the ideXlab platform.
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ticl4 catalyzed Friedel Crafts Reaction of trifluoroacetaldehyde ethyl hemiacetal tfae
ChemInform, 2012Co-Authors: Jing Zhang, Yong-jun Chen, Liang ZhangAbstract:A novel strictly hydroxyl-directed Friedel—Crafts Reaction of various phenols with trifluoroacetaldehyde ethyl hemiacetal (II) is reported.
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TiCl4-Catalyzed Friedel—Crafts Reaction of Trifluoroacetaldehyde Ethyl Hemiacetal (TFAE).
ChemInform, 2012Co-Authors: Jing Zhang, Yong-jun Chen, Liang ZhangAbstract:A novel strictly hydroxyl-directed Friedel—Crafts Reaction of various phenols with trifluoroacetaldehyde ethyl hemiacetal (II) is reported.
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TiCl4-Catalyzed Friedel–Crafts Reaction of Trifluoroacetaldehyde Ethyl Hemiacetal (TFAE)
Synthetic Communications, 2011Co-Authors: Jing Zhang, Yong-jun Chen, Liang ZhangAbstract:Abstract The TiCl4-catalyzed Friedel–Crafts Reaction with trifluoroacetaldehyde ethyl hemiacetal is shown to serve as an efficient route for the synthesis of CF3-substitituted compounds of biological and synthetic importance, producing 2,2,2-trifluoroethyl phenols in good yields under mild conditions.
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ticl4 catalyzed Friedel Crafts Reaction of trifluoroacetaldehyde ethyl hemiacetal tfae
Synthetic Communications, 2011Co-Authors: Jing Zhang, Yong-jun Chen, Liang ZhangAbstract:Abstract The TiCl4-catalyzed Friedel–Crafts Reaction with trifluoroacetaldehyde ethyl hemiacetal is shown to serve as an efficient route for the synthesis of CF3-substitituted compounds of biological and synthetic importance, producing 2,2,2-trifluoroethyl phenols in good yields under mild conditions.
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highly diastereoselective synthesis of n protected arylglycine derivatives via ticl4 promoted Friedel Crafts Reaction of phenols with chiral n o hemiacetal
Synlett, 2002Co-Authors: Yong-jun Chen, Dong WangAbstract:The optically active N-protected arylglycine derivatives were obtained via TiCl 4 -promoted Friedel-Crafts Reaction of various phenols with chiral N,O-hemiacetals in excellent diastereoselectivity.
Masaharu Nakamura - One of the best experts on this subject based on the ideXlab platform.
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tandem phospha Friedel Crafts Reaction toward curved π conjugated frameworks with a phosphorus ring junction
ChemInform, 2011Co-Authors: Takuji Hatakeyama, Sigma Hashimoto, Masaharu NakamuraAbstract:m-Teraryl iodides are subjected to lithium—halogen exchange with subsequent trapping with PCl3 and tandem phospha-Friedel—Crafts Reaction to afford the heptacyclic phosphine sulfudes (II).
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Tandem Phospha-Friedel—Crafts Reaction Toward Curved π-Conjugated Frameworks with a Phosphorus Ring Junction.
ChemInform, 2011Co-Authors: Takuji Hatakeyama, Sigma Hashimoto, Masaharu NakamuraAbstract:m-Teraryl iodides are subjected to lithium—halogen exchange with subsequent trapping with PCl3 and tandem phospha-Friedel—Crafts Reaction to afford the heptacyclic phosphine sulfudes (II).
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tandem phospha Friedel Crafts Reaction toward curved π conjugated frameworks with a phosphorus ring junction
Organic Letters, 2011Co-Authors: Takuji Hatakeyama, Sigma Hashimoto, Masaharu NakamuraAbstract:The tandem phospha-Friedel−Crafts Reaction transforms dichloro(m-teraryl)phosphine to the corresponding triarylphosphine derivatives containing curved π-conjugated frameworks with a phosphorus ring junction. The rigid molecular frameworks enable these unprecedented phosphine compounds to hold an extended π-conjugation spread over the whole molecule.
Hai-bing Zhou - One of the best experts on this subject based on the ideXlab platform.
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Enhanced efficiency of recyclable C3-symmetric cinchonine-squaramides in the asymmetric Friedel–Crafts Reaction of indoles with alkyl trifluoropyruvate
Tetrahedron-asymmetry, 2012Co-Authors: Xin Han, Hai-bing Zhou, Bin Liu, Chune DongAbstract:Abstract The highly enantioselective Friedel–Crafts Reaction of indoles with trifluoropyruvate catalyzed by a C 3 -symmetric cinchonine-squaramide is reported. A wide variety of trifluoromethylated indole derivatives were obtained in high yields and with excellent enantioselectivities (99% and up to >99% ee). Moreover the C 3 catalyst can be easily recovered and was used five times.
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enhanced efficiency of recyclable c3 symmetric cinchonine squaramides in the asymmetric Friedel Crafts Reaction of indoles with alkyl trifluoropyruvate
Tetrahedron-asymmetry, 2012Co-Authors: Xin Han, Hai-bing Zhou, Bin Liu, Chune DongAbstract:Abstract The highly enantioselective Friedel–Crafts Reaction of indoles with trifluoropyruvate catalyzed by a C 3 -symmetric cinchonine-squaramide is reported. A wide variety of trifluoromethylated indole derivatives were obtained in high yields and with excellent enantioselectivities (99% and up to >99% ee). Moreover the C 3 catalyst can be easily recovered and was used five times.
