Friedreichs Ataxia

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Mahmut Durmus - One of the best experts on this subject based on the ideXlab platform.

  • Anesthetic Management on a Patient with Friedreichs Ataxia
    Society of TURAZ AKADEMI, 2013
    Co-Authors: Ulku Ozgul, Mehmet Ali Erdogan, Mustafa Said Aydogan, Mehmet Fatih Korkmaz, Hamza Nakir, Mahmut Durmus
    Abstract:

    Friedreichs Ataxia is a rare (1:50 000) autosomal recessively inherited neurodegenerative disorder. Findings such as weakness in skeletal muscles, progressive difficulty in walking and extremity Ataxia are prominent. Problems such as cardiac, endocrine, pulmonary and neuromuscular dysfunction may affect the anesthesia method of patients with Friedreichs Ataxia. In this case, we wanted to present our anesthetic management to a patient with Friedreichs Ataxia who underwent posterior spinal fusion operation due to kyphoscoliosis. [Med-Science 2013; 2(4.000): 928-34

  • Anesthetic Management on a Patient with Friedreich’s Ataxia
    Medicine Science | International Medical Journal, 2013
    Co-Authors: Ulku Ozgul, Mustafa Said Aydogan, Mehmet Fatih Korkmaz, Hamza Nakir, Mehmet Erdogan, Mahmut Durmus
    Abstract:

    Friedreichs Ataxia is a rare (1:50 000) autosomal recessively inherited neurodegenerative disorder. Findings such as weakness in skeletal muscles, progressive difficulty in walking and extremity Ataxia are prominent. Problems such as cardiac, endocrine, pulmonary and neuromuscular dysfunction may affect the anesthesia method of patients with Friedreichs Ataxia. In this case, we wanted to present our anesthetic management to a patient with Friedreichs Ataxia who underwent posterior spinal fusion operation due to kyphoscoliosis.

Ulku Ozgul - One of the best experts on this subject based on the ideXlab platform.

  • Anesthetic Management on a Patient with Friedreichs Ataxia
    Society of TURAZ AKADEMI, 2013
    Co-Authors: Ulku Ozgul, Mehmet Ali Erdogan, Mustafa Said Aydogan, Mehmet Fatih Korkmaz, Hamza Nakir, Mahmut Durmus
    Abstract:

    Friedreichs Ataxia is a rare (1:50 000) autosomal recessively inherited neurodegenerative disorder. Findings such as weakness in skeletal muscles, progressive difficulty in walking and extremity Ataxia are prominent. Problems such as cardiac, endocrine, pulmonary and neuromuscular dysfunction may affect the anesthesia method of patients with Friedreichs Ataxia. In this case, we wanted to present our anesthetic management to a patient with Friedreichs Ataxia who underwent posterior spinal fusion operation due to kyphoscoliosis. [Med-Science 2013; 2(4.000): 928-34

  • Anesthetic Management on a Patient with Friedreich’s Ataxia
    Medicine Science | International Medical Journal, 2013
    Co-Authors: Ulku Ozgul, Mustafa Said Aydogan, Mehmet Fatih Korkmaz, Hamza Nakir, Mehmet Erdogan, Mahmut Durmus
    Abstract:

    Friedreichs Ataxia is a rare (1:50 000) autosomal recessively inherited neurodegenerative disorder. Findings such as weakness in skeletal muscles, progressive difficulty in walking and extremity Ataxia are prominent. Problems such as cardiac, endocrine, pulmonary and neuromuscular dysfunction may affect the anesthesia method of patients with Friedreichs Ataxia. In this case, we wanted to present our anesthetic management to a patient with Friedreichs Ataxia who underwent posterior spinal fusion operation due to kyphoscoliosis.

Marco Montorsi - One of the best experts on this subject based on the ideXlab platform.

  • coenzyme q10 in neuromuscular and neurodegenerative disorders
    Current Drug Targets, 2010
    Co-Authors: Michelangelo Mancuso, Daniele Orsucci, Leda Volpi, Valeria Calsolaro, Gabriele Siciliano, Carme Correale, Hajnalka Szabo, Antonino Spinelli, Marco Montorsi
    Abstract:

    Coenzyme Q10 (CoQ10, or ubiquinone) is an electron carrier of the mitochondrial respiratory chain (electron transport chain) with antioxidant properties. In view of the involvement of CoQ10 in oxidative phosphorylation and cellular antioxidant protection a deficiency in this quinone would be expected to contribute to disease pathophysiology by causing a failure in energy metabolism and antioxidant status. Indeed, a deficit in CoQ10 status has been determined in a number of neuromuscular and neurodegenerative disorders. Primary disorders of CoQ10 biosynthesis are potentially treatable conditions and therefore a high degree of clinical awareness about this condition is essential. A secondary loss of CoQ10 status following HMG-Coa reductase inhibitor (statins) treatment has been implicated in the pathophysiology of the myotoxicity associated with this pharmacotherapy. CoQ10 and its analogue, idebenone, have been widely used in the treatment of neurodegenerative and neuromuscular disorders. These compounds could potentially play a role in the treatment of mitochondrial disorders, Parkinsons disease, Huntingtons disease, amyotrophic lateral sclerosis, Friedreichs Ataxia, and other conditions which have been linked to mitochondrial dysfunction. This article reviews the physiological roles of CoQ10, as well as the rationale and the role in clinical practice of CoQ10 supplementation in different neurological and muscular diseases, from primary CoQ10 deficiency to neurodegenerative disorders. We also briefly report a case of the myopathic form of CoQ10 deficiency.

Hamza Nakir - One of the best experts on this subject based on the ideXlab platform.

  • Anesthetic Management on a Patient with Friedreichs Ataxia
    Society of TURAZ AKADEMI, 2013
    Co-Authors: Ulku Ozgul, Mehmet Ali Erdogan, Mustafa Said Aydogan, Mehmet Fatih Korkmaz, Hamza Nakir, Mahmut Durmus
    Abstract:

    Friedreichs Ataxia is a rare (1:50 000) autosomal recessively inherited neurodegenerative disorder. Findings such as weakness in skeletal muscles, progressive difficulty in walking and extremity Ataxia are prominent. Problems such as cardiac, endocrine, pulmonary and neuromuscular dysfunction may affect the anesthesia method of patients with Friedreichs Ataxia. In this case, we wanted to present our anesthetic management to a patient with Friedreichs Ataxia who underwent posterior spinal fusion operation due to kyphoscoliosis. [Med-Science 2013; 2(4.000): 928-34

  • Anesthetic Management on a Patient with Friedreich’s Ataxia
    Medicine Science | International Medical Journal, 2013
    Co-Authors: Ulku Ozgul, Mustafa Said Aydogan, Mehmet Fatih Korkmaz, Hamza Nakir, Mehmet Erdogan, Mahmut Durmus
    Abstract:

    Friedreichs Ataxia is a rare (1:50 000) autosomal recessively inherited neurodegenerative disorder. Findings such as weakness in skeletal muscles, progressive difficulty in walking and extremity Ataxia are prominent. Problems such as cardiac, endocrine, pulmonary and neuromuscular dysfunction may affect the anesthesia method of patients with Friedreichs Ataxia. In this case, we wanted to present our anesthetic management to a patient with Friedreichs Ataxia who underwent posterior spinal fusion operation due to kyphoscoliosis.

Mehmet Fatih Korkmaz - One of the best experts on this subject based on the ideXlab platform.

  • Anesthetic Management on a Patient with Friedreichs Ataxia
    Society of TURAZ AKADEMI, 2013
    Co-Authors: Ulku Ozgul, Mehmet Ali Erdogan, Mustafa Said Aydogan, Mehmet Fatih Korkmaz, Hamza Nakir, Mahmut Durmus
    Abstract:

    Friedreichs Ataxia is a rare (1:50 000) autosomal recessively inherited neurodegenerative disorder. Findings such as weakness in skeletal muscles, progressive difficulty in walking and extremity Ataxia are prominent. Problems such as cardiac, endocrine, pulmonary and neuromuscular dysfunction may affect the anesthesia method of patients with Friedreichs Ataxia. In this case, we wanted to present our anesthetic management to a patient with Friedreichs Ataxia who underwent posterior spinal fusion operation due to kyphoscoliosis. [Med-Science 2013; 2(4.000): 928-34

  • Anesthetic Management on a Patient with Friedreich’s Ataxia
    Medicine Science | International Medical Journal, 2013
    Co-Authors: Ulku Ozgul, Mustafa Said Aydogan, Mehmet Fatih Korkmaz, Hamza Nakir, Mehmet Erdogan, Mahmut Durmus
    Abstract:

    Friedreichs Ataxia is a rare (1:50 000) autosomal recessively inherited neurodegenerative disorder. Findings such as weakness in skeletal muscles, progressive difficulty in walking and extremity Ataxia are prominent. Problems such as cardiac, endocrine, pulmonary and neuromuscular dysfunction may affect the anesthesia method of patients with Friedreichs Ataxia. In this case, we wanted to present our anesthetic management to a patient with Friedreichs Ataxia who underwent posterior spinal fusion operation due to kyphoscoliosis.