The Experts below are selected from a list of 51 Experts worldwide ranked by ideXlab platform
Ross S. Kalucy - One of the best experts on this subject based on the ideXlab platform.
-
Parents with mental illness: lacking motivation to parent.
International journal of mental health nursing, 2003Co-Authors: Lyndall Thomas, Ross S. KalucyAbstract:ABSTRACT: Parents with mental illness sometimes struggle to manage the demands of a family and the disabling symptoms of their illness. Limited interaction and poor relationships can negatively impact on children. Lack of motivation may inhibit these parents’ ability to interact with, and provide adequate care for their children. This is especially problematic following a hospital admission. Lack of motivation, in psychiatric illnesses, can be a symptom, due to medication, or perhaps associated with Frontal Lobe Disorder. Assessment, rehabilitation and support that focuses on parents’ problems with motivation and planning and enhances their parenting would be beneficial in helping parents with mental illness provide the best possible care for their children.
Bastiaan C. Ter Meulen - One of the best experts on this subject based on the ideXlab platform.
-
Olfactory neuroblastoma: A Frontal Lobe Disorder and a runny nose
Neurology, 2016Co-Authors: Tim Van Osch, Henri A.j.m. Overtoom, Bastiaan C. Ter MeulenAbstract:A 56-year-old woman presented with progressive apathy, expressive aphasia, urinary incontinence, and a subtle right hemiparesis. She had a recent history of clear rhinorrhea and frequent nosebleeds. CT and MRI scan revealed a large mass in the left nasal cavity extending into the Frontal Lobe (figure 1). The diagnosis of olfactory neuroblastoma was confirmed by transnasal biopsy (figure 2). A combined treatment of chemotherapy and radiotherapy was suggested. Before treatment could be initiated, the patient died of a major hemorrhage in the tumor. Acknowledgment: The authors thank M.J. Flens for providing the pathology slides and explanation.
Kenneth M. Heilman - One of the best experts on this subject based on the ideXlab platform.
-
Ventral tegmental area injury and Frontal Lobe Disorder.
Neurology, 1996Co-Authors: John C. Adair, David J.g. Williamson, Ronald L. Schwartz, Kenneth M. HeilmanAbstract:A patient developed acute behavioral changes implicating Frontal-executive dysfunction. His clinical signs suggested mesencephalic injury, and a cranial MRI scan showed an abnormality restricted to a small region of the ventral midbrain. We suggest that the patient's behavioral Disorder originated from disruption of the ventral tegmental area or its projections, structures that influence Frontal brain processes via the mesocortical dopamine tract.
D. Wertheimer - One of the best experts on this subject based on the ideXlab platform.
-
P 83 Parasomnia, parkinsonism, impulse control Disorder and bulbar palsy with IgLON5 antibodies: A new case report
Clinical Neurophysiology, 2017Co-Authors: K. Lange, L. De Azevedo, F. Garzia, J. Hezel, K.k. Falk, F. Leypoldt, D. WertheimerAbstract:Background In 2014 a complex neurological syndrome with parasomnia, sleep breathing dysfunction and variable bulbar symptoms associated with antibodies to IgLON5, a neuronal cell-adhesion protein, was described (Sabater et al., 2016). Postmortal studies revealed tauopathy predominately involving the hypothalamus and tegmentum of the brainstem (Gelpi et al., 2016). To the best of our knowledge, there are 16 published cases so far. Methods (clinical presentation) We report a 72-year-old highly educated male Caucasian patient with a 6 year history of parasomnia with RBD in the beginning, following of multiple falls, parkinsonism, hypomania, Frontal Lobe Disorder and impulse control Disorder (ICD; leading to sentence of detention) with aggressive tendencies. By transcranial ultrasound hyperechogenicity of substantia nigra was demonstrated, FDG-PET imaging showed lower 18F-FDG activity in temporal Lobes. Thus idiopathic Parkinson’s disease was assumed. Due to neuropsychiatric complications the antiparkinson medication was gradually reduced and eventually discontinued in 2014. Interestingly, there were no relevant changes in symptoms of parkinsonism thereafter. In 2016, after acute coronary syndrome the patient developed a sudden bilateral vocal cord paresis with stridor leading to intubation and following tracheotomy. Subsequently, he showed dysphagia, increasing rigidity, fluctuating level of consciousness with intermittent hypoventilation and hypercapnia, and autonomic dysregulation. Critical decompensation with need of short CPR occurred twice, continuous monitoring with mechanical ventilation was required. Results (workup and treatment, Table 1 ) Brain MRI showed iron accumulation in globus pallidus and dentate nucleus, and a small pineal cyst ( Fig. 1 a). The initial multiple EEGs were normal. Diverse EEGs from 2016 registered generalized slowing with intermittent hyperexcitability; nonconvulsive status epilepticus was captured once ( Fig. 1 b). Laboratory tests displayed neutrophil leukocytosis with MGUS IgG-kappa and -lambda. In serum (1:100) and in CSF (1:10) IgLON5 antibodies (IgG subclass) were detected. HLA-typing revealed HLA-DRB1∗10:01 and HLA-DQB1∗05:01 alleles. Tumor screening (thoracic and abdominal CT, bone marrow examination) did not detect malignancy. Because of suspected IgLON5-syndrome with autoimmune origin an immunosuppressive therapy with initial IV methylprednisolone pulse therapy following oral prednisolone (75 mg/d) and rituximab was initiated. Subsequently, after achieving better vigilance, it was possible to start weaning again. Conclusion Parasomnia, ICD, beginning Frontal Lobe syndrome with parkinsonism, multiple falls and bulbar symptoms is a new combination in IgLON5 antibody-linked syndrome. A connection to neurodegeneration with brain iron accumulation (NBIA) is possible and requires further investigation.
Lyndall Thomas - One of the best experts on this subject based on the ideXlab platform.
-
Parents with mental illness: lacking motivation to parent.
International journal of mental health nursing, 2003Co-Authors: Lyndall Thomas, Ross S. KalucyAbstract:ABSTRACT: Parents with mental illness sometimes struggle to manage the demands of a family and the disabling symptoms of their illness. Limited interaction and poor relationships can negatively impact on children. Lack of motivation may inhibit these parents’ ability to interact with, and provide adequate care for their children. This is especially problematic following a hospital admission. Lack of motivation, in psychiatric illnesses, can be a symptom, due to medication, or perhaps associated with Frontal Lobe Disorder. Assessment, rehabilitation and support that focuses on parents’ problems with motivation and planning and enhances their parenting would be beneficial in helping parents with mental illness provide the best possible care for their children.
