The Experts below are selected from a list of 33 Experts worldwide ranked by ideXlab platform
Frédéric Bihel - One of the best experts on this subject based on the ideXlab platform.
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POxAP Precatalysts and the Negishi Cross-Coupling Reaction
Synthesis, 2019Co-Authors: Shuang-qi Tang, Martine Schmitt, Frédéric BihelAbstract:Recently developed for the Fukuyama Reaction, post-oxidative addition precatalysts (POxAPs) are also very efficient in catalyzing Negishi cross-coupling Reactions between organohalides and organozinc reagents. Using very low catalyst loadings, POxAPs show similar catalytic activities to those of classical precatalysts such as XPhos Pd G4 or PEPPSI-IPr, with turnover numbers of up to 93,000. POxAPs are easily prepared, are stable to air and moisture, tolerate a wide range of functional groups in the Negishi cross-coupling Reaction and contribute advantageously to the arsenal of organic chemists in terms of Pd precatalysts.
Rabia Akhtar - One of the best experts on this subject based on the ideXlab platform.
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Fukuyama reduction, Fukuyama coupling and Fukuyama–Mitsunobu alkylation: recent developments and synthetic applications
Molecular Diversity, 2021Co-Authors: Sana Sikandar, Ameer Fawad Zahoor, Shazia Naheed, Bushra Parveen, Kulsoom Ghulam Ali, Rabia AkhtarAbstract:Fukuyama Reaction for the synthesis of multifunctional aldehydes, secondary amines and ketones has gained considerable importance in synthetic organic chemistry because of mild Reaction conditions. The use of thioesters in both Fukuyama aldehydes and ketones synthesis is highly attractive for organic chemists as they are easily accessible from corresponding carboxylic acids. Fukuyama–Mitsunobu Reaction utilizes 2-nitrobenzenesulfonyl (Ns) for the protection/activation/deprotection of primary amines to afford secondary amines in good yields and high enantioselectivities. This review presents recent synthetic developments and applications of Fukuyama Reaction for the synthesis of aldehydes, secondary amines and ketones. Graphic abstract
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Fukuyama reduction, Fukuyama coupling and Fukuyama-Mitsunobu alkylation: recent developments and synthetic applications.
Molecular diversity, 2021Co-Authors: Sana Sikandar, Ameer Fawad Zahoor, Shazia Naheed, Bushra Parveen, Kulsoom Ghulam Ali, Rabia AkhtarAbstract:Fukuyama Reaction for the synthesis of multifunctional aldehydes, secondary amines and ketones has gained considerable importance in synthetic organic chemistry because of mild Reaction conditions. The use of thioesters in both Fukuyama aldehydes and ketones synthesis is highly attractive for organic chemists as they are easily accessible from corresponding carboxylic acids. Fukuyama-Mitsunobu Reaction utilizes 2-nitrobenzenesulfonyl (Ns) for the protection/activation/deprotection of primary amines to afford secondary amines in good yields and high enantioselectivities. This review presents recent synthetic developments and applications of Fukuyama Reaction for the synthesis of aldehydes, secondary amines and ketones.
Shuang-qi Tang - One of the best experts on this subject based on the ideXlab platform.
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POxAP Precatalysts and the Negishi Cross-Coupling Reaction
Synthesis, 2019Co-Authors: Shuang-qi Tang, Martine Schmitt, Frédéric BihelAbstract:Recently developed for the Fukuyama Reaction, post-oxidative addition precatalysts (POxAPs) are also very efficient in catalyzing Negishi cross-coupling Reactions between organohalides and organozinc reagents. Using very low catalyst loadings, POxAPs show similar catalytic activities to those of classical precatalysts such as XPhos Pd G4 or PEPPSI-IPr, with turnover numbers of up to 93,000. POxAPs are easily prepared, are stable to air and moisture, tolerate a wide range of functional groups in the Negishi cross-coupling Reaction and contribute advantageously to the arsenal of organic chemists in terms of Pd precatalysts.
Sana Sikandar - One of the best experts on this subject based on the ideXlab platform.
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Fukuyama reduction, Fukuyama coupling and Fukuyama–Mitsunobu alkylation: recent developments and synthetic applications
Molecular Diversity, 2021Co-Authors: Sana Sikandar, Ameer Fawad Zahoor, Shazia Naheed, Bushra Parveen, Kulsoom Ghulam Ali, Rabia AkhtarAbstract:Fukuyama Reaction for the synthesis of multifunctional aldehydes, secondary amines and ketones has gained considerable importance in synthetic organic chemistry because of mild Reaction conditions. The use of thioesters in both Fukuyama aldehydes and ketones synthesis is highly attractive for organic chemists as they are easily accessible from corresponding carboxylic acids. Fukuyama–Mitsunobu Reaction utilizes 2-nitrobenzenesulfonyl (Ns) for the protection/activation/deprotection of primary amines to afford secondary amines in good yields and high enantioselectivities. This review presents recent synthetic developments and applications of Fukuyama Reaction for the synthesis of aldehydes, secondary amines and ketones. Graphic abstract
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Fukuyama reduction, Fukuyama coupling and Fukuyama-Mitsunobu alkylation: recent developments and synthetic applications.
Molecular diversity, 2021Co-Authors: Sana Sikandar, Ameer Fawad Zahoor, Shazia Naheed, Bushra Parveen, Kulsoom Ghulam Ali, Rabia AkhtarAbstract:Fukuyama Reaction for the synthesis of multifunctional aldehydes, secondary amines and ketones has gained considerable importance in synthetic organic chemistry because of mild Reaction conditions. The use of thioesters in both Fukuyama aldehydes and ketones synthesis is highly attractive for organic chemists as they are easily accessible from corresponding carboxylic acids. Fukuyama-Mitsunobu Reaction utilizes 2-nitrobenzenesulfonyl (Ns) for the protection/activation/deprotection of primary amines to afford secondary amines in good yields and high enantioselectivities. This review presents recent synthetic developments and applications of Fukuyama Reaction for the synthesis of aldehydes, secondary amines and ketones.
Martine Schmitt - One of the best experts on this subject based on the ideXlab platform.
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POxAP Precatalysts and the Negishi Cross-Coupling Reaction
Synthesis, 2019Co-Authors: Shuang-qi Tang, Martine Schmitt, Frédéric BihelAbstract:Recently developed for the Fukuyama Reaction, post-oxidative addition precatalysts (POxAPs) are also very efficient in catalyzing Negishi cross-coupling Reactions between organohalides and organozinc reagents. Using very low catalyst loadings, POxAPs show similar catalytic activities to those of classical precatalysts such as XPhos Pd G4 or PEPPSI-IPr, with turnover numbers of up to 93,000. POxAPs are easily prepared, are stable to air and moisture, tolerate a wide range of functional groups in the Negishi cross-coupling Reaction and contribute advantageously to the arsenal of organic chemists in terms of Pd precatalysts.
