The Experts below are selected from a list of 78 Experts worldwide ranked by ideXlab platform
Wenfu Kao - One of the best experts on this subject based on the ideXlab platform.
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lightweight hardware Return address and stack frame tracking to prevent Function Return address attack
Computational Science and Engineering, 2009Co-Authors: Wenfu KaoAbstract:Supporting security features in hardware is relatively recent. Adding extra protection at the architectural-level is effective and can improve the existing software protection. In this paper, we discuss the challenges and considerations of adding a security enhancement inside hardware. We also demonstrated a light-weight architecture design change under the constraint to prevent from Function Return address attack by tracking the active Return address and stack frame pointer, and raising a warning upon the Return of a Function if the Return address has been modified. The idea is as effective as other hardware solutions but significantly reduces the hardware changes and performance overhead, and is transparent to software. The preliminary result showed 89% of the Return address is covered by our heuristic tracking method.
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CSE (2) - Lightweight Hardware Return Address and Stack Frame Tracking to Prevent Function Return Address Attack
2009 International Conference on Computational Science and Engineering, 2009Co-Authors: Wenfu KaoAbstract:Supporting security features in hardware is relatively recent. Adding extra protection at the architectural-level is effective and can improve the existing software protection. In this paper, we discuss the challenges and considerations of adding a security enhancement inside hardware. We also demonstrated a light-weight architecture design change under the constraint to prevent from Function Return address attack by tracking the active Return address and stack frame pointer, and raising a warning upon the Return of a Function if the Return address has been modified. The idea is as effective as other hardware solutions but significantly reduces the hardware changes and performance overhead, and is transparent to software. The preliminary result showed 89% of the Return address is covered by our heuristic tracking method.
Peter C. Lim - One of the best experts on this subject based on the ideXlab platform.
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Comparative analysis of genitourinary Function after type C1 robotic nerve-sparing radical hysterectomy versus type C2 robotic radical hysterectomy
Surgical oncology, 2019Co-Authors: Jiheum Paek, Elizabeth Kang, Peter C. LimAbstract:Abstract Background To compare the Return of bladder Function and genitourinary complications after type C1 robotic nerve-sparing radical hysterectomy (C1-RRH) to type C2 robotic radical hysterectomy (C2-RRH) in gynecologic cancers. Methods A retrospective analysis between C1-RRH (n = 42) and C2-RRH (n = 43) was performed. Operative outcomes and perioperative genitourinary complications between the two groups were analyzed. Results The C1-RRH group had shorter hospitalization (0.7 vs. 1.7 days, p 6 weeks). In spite of the short stay after surgery (95% of C1-RRH ≤ 1 day), only two patients (4.8%) in C1-RRH group were admitted again because of urinary tract infection. C1-RRH was only independent predictor for early bladder Function Return within 1 week after surgery. Conclusion The C1-RRH showed early bladder Function Return and feasible outcomes in spite of early discharge. It can be considered as the first surgical option in gynecologic cancer patients who need RH to preserve their bladder Function.
James T Heaton - One of the best experts on this subject based on the ideXlab platform.
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the effects of potential neuroprotective agents on rat facial Function recovery following facial nerve injury
Otolaryngology-Head and Neck Surgery, 2011Co-Authors: Kalpesh T Vakharia, Robin W Lindsay, Christopher J Knox, Colin Edwards, Doug Henstrom, Julie S Weinberg, Tessa A Hadlock, James T HeatonAbstract:Objective. To evaluate whether a series of pharmacologic agents with potential neuroprotective effects accelerate and/ or improve facial Function recovery after facial nerve crush injury. Study Design. Randomized animal study. Setting. Tertiary care facility. Methods. Eighty female Wistar-Hannover rats underwent head restraint implantation and daily conditioning. Animals then underwent unilateral crush injury to the main trunk of the facial nerve and were randomized to receive treatment with atorvastatin (n = 10), sildenafil (n = 10), darbepoetin (n = 20), or a corresponding control agent (n = 40). The Return of whisking Function was tracked throughout the recovery period. Results. All rats initiated the Return of whisking Function from nerve crush by day 12. Darbepoetin-treated rats (n = 20) showed significantly improved whisking amplitude and velocity across the recovery period, with several days of significant pairwise differences vs comparable control rats (n = 16) across the first 2 weeks of whisking Function Return. In contrast, rats treated with sildenafil (n = 10) and atorvastatin (n = 10) did not show significant improvement in whisking Function recovery after facial nerve crush compared to controls. By week 8, all darbepoetin-treated animals and comparable nerve crush control animals fully recovered whisking Function and were statistically indistinguishable. Conclusion. Among the 3 potentially neuroprotective agents evaluated, only darbepoetin administration resulted in accelerated recovery of whisking parameters after facial nerve crush injury. Further efforts to define the mechanism of action and translate these findings to the use of darbepoetin in the care of patients with traumatic facial paralysis are needed.
Jiheum Paek - One of the best experts on this subject based on the ideXlab platform.
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Comparative analysis of genitourinary Function after type C1 robotic nerve-sparing radical hysterectomy versus type C2 robotic radical hysterectomy
Surgical oncology, 2019Co-Authors: Jiheum Paek, Elizabeth Kang, Peter C. LimAbstract:Abstract Background To compare the Return of bladder Function and genitourinary complications after type C1 robotic nerve-sparing radical hysterectomy (C1-RRH) to type C2 robotic radical hysterectomy (C2-RRH) in gynecologic cancers. Methods A retrospective analysis between C1-RRH (n = 42) and C2-RRH (n = 43) was performed. Operative outcomes and perioperative genitourinary complications between the two groups were analyzed. Results The C1-RRH group had shorter hospitalization (0.7 vs. 1.7 days, p 6 weeks). In spite of the short stay after surgery (95% of C1-RRH ≤ 1 day), only two patients (4.8%) in C1-RRH group were admitted again because of urinary tract infection. C1-RRH was only independent predictor for early bladder Function Return within 1 week after surgery. Conclusion The C1-RRH showed early bladder Function Return and feasible outcomes in spite of early discharge. It can be considered as the first surgical option in gynecologic cancer patients who need RH to preserve their bladder Function.
Christopher M Duncan - One of the best experts on this subject based on the ideXlab platform.
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more predictable Return of motor Function with mepivacaine versus bupivacaine spinal anesthetic in total hip and total knee arthroplasty a double blinded randomized clinical trial
Journal of Bone and Joint Surgery American Volume, 2020Co-Authors: Cody C Wyles, Mark W Pagnano, Robert T Trousdale, Rafael J Sierra, Michael J Taunton, Kevin I Perry, Dirk R Larson, Adam W Amundson, Hugh M Smith, Christopher M DuncanAbstract:BACKGROUND Spinal anesthesia provides several benefits for patients undergoing total hip arthroplasty (THA) and total knee arthroplasty (TKA), but historically comes at the cost of slow and unpredictable Return of lower-extremity motor Function related to the use of long-acting local anesthetics. In this prospective, double-blinded, randomized clinical trial we sought to determine if an alternative local anesthetic, mepivacaine, would allow more consistent Return of motor Function compared with low-dose bupivacaine spinal anesthesia during primary THA and TKA. METHODS This trial was conducted at a single academic institution. Prior to trial initiation an internal pilot study determined that 154 patients were required to achieve 80% power. Patients were randomized in a 1:1 fashion with use of advanced computerized stratification based on procedure, age group, sex, and body mass index. Following the surgical procedure, motor Function was assessed every 15 minutes in the nonoperative lower extremity according to the Bromage scale and discontinued once Bromage 0 was achieved (spontaneous movement at hip, knee, and ankle). RESULTS Return of lower-extremity Function was more predictable in patients who received mepivacaine than in those who received low-dose bupivacaine. Among patients who received mepivacaine, 1% achieved motor Function Return beyond 5 hours compared with 11% of patients who received bupivacaine (p = 0.013). The mean time to Return of lower-extremity motor Function was 26 minutes quicker in patients who received mepivacaine (185 minutes; 95% confidence interval, 174 to 196 minutes) compared with low-dose bupivacaine (210 minutes; 95% confidence interval, 193 to 228 minutes) (p = 0.016). There were no significant differences in safety outcomes including pain scores, time to participation in physical therapy, incidence of orthostatic hypotension, urinary retention, or transient neurologic symptoms in patients receiving mepivacaine compared with low-dose bupivacaine. CONCLUSIONS In patients undergoing primary THA and TKA, spinal anesthesia with mepivacaine allowed more consistent Return of lower-extremity motor Function compared with low-dose bupivacaine, without a concomitant increase in complications potentially associated with spinal anesthetics. This is particularly of value in an era of short-stay and outpatient surgical procedures. LEVEL OF EVIDENCE Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
