The Experts below are selected from a list of 57 Experts worldwide ranked by ideXlab platform
Arturo San Feliciano - One of the best experts on this subject based on the ideXlab platform.
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new 1 4 anthracenedione derivatives with Fused Heterocyclic Rings synthesis and biological evaluation
ChemInform, 2015Co-Authors: Ma Angeles Castro, Ana Ma Gamito, Veronica Tangarifecastano, Vicky Roalinares, Jose Miguel M Del Corral, Ana Cecilia Mesaarango, Liliana Betancurgalvis, Andres Francesch, Arturo San FelicianoAbstract:Various terpenylquinones are synthesized by nucleophilic addition or substitution reactions of 1,4-anthracenediones and further transformed into extended polycyclic systems, which mainly keep the 1,4-quinone moiety Fused to different nitrogen- Heterocyclic Rings into the structure.
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new 1 4 anthracenedione derivatives with Fused Heterocyclic Rings synthesis and biological evaluation
RSC Advances, 2015Co-Authors: Ma Angeles Castro, Ana Ma Gamito, Veronica Tangarifecastano, Vicky Roalinares, Jose Miguel M Del Corral, Ana Cecilia Mesaarango, Liliana Betancurgalvis, Andres Francesch, Arturo San FelicianoAbstract:Several terpenylquinones derived from 1,4-anthracenedione (1,4-anthracenequinone, AQ) have been prepared by addition or substitution nucleophilic reactions and further transformed into extended polycyclic systems, which mainly kept the 1,4-quinone moiety Fused to different nitrogen-Heterocyclic Rings (pyrrole, imidazole, pyrazine or quinoxaline) into the structure. The compounds synthesized were evaluated for their antineoplastic, antifungal and antiviral activities. GI50 antineoplastic values remained under μM levels for AQs, while the Heterocyclic derivatives showed antifungal MIC values in the low μg mL−1 range against yeasts and filamentous fungi. Only few compounds displayed a discrete non-selective antiherpetic activity in the μg mL−1 range.
Ma Angeles Castro - One of the best experts on this subject based on the ideXlab platform.
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new 1 4 anthracenedione derivatives with Fused Heterocyclic Rings synthesis and biological evaluation
ChemInform, 2015Co-Authors: Ma Angeles Castro, Ana Ma Gamito, Veronica Tangarifecastano, Vicky Roalinares, Jose Miguel M Del Corral, Ana Cecilia Mesaarango, Liliana Betancurgalvis, Andres Francesch, Arturo San FelicianoAbstract:Various terpenylquinones are synthesized by nucleophilic addition or substitution reactions of 1,4-anthracenediones and further transformed into extended polycyclic systems, which mainly keep the 1,4-quinone moiety Fused to different nitrogen- Heterocyclic Rings into the structure.
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new 1 4 anthracenedione derivatives with Fused Heterocyclic Rings synthesis and biological evaluation
RSC Advances, 2015Co-Authors: Ma Angeles Castro, Ana Ma Gamito, Veronica Tangarifecastano, Vicky Roalinares, Jose Miguel M Del Corral, Ana Cecilia Mesaarango, Liliana Betancurgalvis, Andres Francesch, Arturo San FelicianoAbstract:Several terpenylquinones derived from 1,4-anthracenedione (1,4-anthracenequinone, AQ) have been prepared by addition or substitution nucleophilic reactions and further transformed into extended polycyclic systems, which mainly kept the 1,4-quinone moiety Fused to different nitrogen-Heterocyclic Rings (pyrrole, imidazole, pyrazine or quinoxaline) into the structure. The compounds synthesized were evaluated for their antineoplastic, antifungal and antiviral activities. GI50 antineoplastic values remained under μM levels for AQs, while the Heterocyclic derivatives showed antifungal MIC values in the low μg mL−1 range against yeasts and filamentous fungi. Only few compounds displayed a discrete non-selective antiherpetic activity in the μg mL−1 range.
Vicky Roalinares - One of the best experts on this subject based on the ideXlab platform.
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new 1 4 anthracenedione derivatives with Fused Heterocyclic Rings synthesis and biological evaluation
ChemInform, 2015Co-Authors: Ma Angeles Castro, Ana Ma Gamito, Veronica Tangarifecastano, Vicky Roalinares, Jose Miguel M Del Corral, Ana Cecilia Mesaarango, Liliana Betancurgalvis, Andres Francesch, Arturo San FelicianoAbstract:Various terpenylquinones are synthesized by nucleophilic addition or substitution reactions of 1,4-anthracenediones and further transformed into extended polycyclic systems, which mainly keep the 1,4-quinone moiety Fused to different nitrogen- Heterocyclic Rings into the structure.
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new 1 4 anthracenedione derivatives with Fused Heterocyclic Rings synthesis and biological evaluation
RSC Advances, 2015Co-Authors: Ma Angeles Castro, Ana Ma Gamito, Veronica Tangarifecastano, Vicky Roalinares, Jose Miguel M Del Corral, Ana Cecilia Mesaarango, Liliana Betancurgalvis, Andres Francesch, Arturo San FelicianoAbstract:Several terpenylquinones derived from 1,4-anthracenedione (1,4-anthracenequinone, AQ) have been prepared by addition or substitution nucleophilic reactions and further transformed into extended polycyclic systems, which mainly kept the 1,4-quinone moiety Fused to different nitrogen-Heterocyclic Rings (pyrrole, imidazole, pyrazine or quinoxaline) into the structure. The compounds synthesized were evaluated for their antineoplastic, antifungal and antiviral activities. GI50 antineoplastic values remained under μM levels for AQs, while the Heterocyclic derivatives showed antifungal MIC values in the low μg mL−1 range against yeasts and filamentous fungi. Only few compounds displayed a discrete non-selective antiherpetic activity in the μg mL−1 range.
Ana Ma Gamito - One of the best experts on this subject based on the ideXlab platform.
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new 1 4 anthracenedione derivatives with Fused Heterocyclic Rings synthesis and biological evaluation
ChemInform, 2015Co-Authors: Ma Angeles Castro, Ana Ma Gamito, Veronica Tangarifecastano, Vicky Roalinares, Jose Miguel M Del Corral, Ana Cecilia Mesaarango, Liliana Betancurgalvis, Andres Francesch, Arturo San FelicianoAbstract:Various terpenylquinones are synthesized by nucleophilic addition or substitution reactions of 1,4-anthracenediones and further transformed into extended polycyclic systems, which mainly keep the 1,4-quinone moiety Fused to different nitrogen- Heterocyclic Rings into the structure.
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new 1 4 anthracenedione derivatives with Fused Heterocyclic Rings synthesis and biological evaluation
RSC Advances, 2015Co-Authors: Ma Angeles Castro, Ana Ma Gamito, Veronica Tangarifecastano, Vicky Roalinares, Jose Miguel M Del Corral, Ana Cecilia Mesaarango, Liliana Betancurgalvis, Andres Francesch, Arturo San FelicianoAbstract:Several terpenylquinones derived from 1,4-anthracenedione (1,4-anthracenequinone, AQ) have been prepared by addition or substitution nucleophilic reactions and further transformed into extended polycyclic systems, which mainly kept the 1,4-quinone moiety Fused to different nitrogen-Heterocyclic Rings (pyrrole, imidazole, pyrazine or quinoxaline) into the structure. The compounds synthesized were evaluated for their antineoplastic, antifungal and antiviral activities. GI50 antineoplastic values remained under μM levels for AQs, while the Heterocyclic derivatives showed antifungal MIC values in the low μg mL−1 range against yeasts and filamentous fungi. Only few compounds displayed a discrete non-selective antiherpetic activity in the μg mL−1 range.
Veronica Tangarifecastano - One of the best experts on this subject based on the ideXlab platform.
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new 1 4 anthracenedione derivatives with Fused Heterocyclic Rings synthesis and biological evaluation
ChemInform, 2015Co-Authors: Ma Angeles Castro, Ana Ma Gamito, Veronica Tangarifecastano, Vicky Roalinares, Jose Miguel M Del Corral, Ana Cecilia Mesaarango, Liliana Betancurgalvis, Andres Francesch, Arturo San FelicianoAbstract:Various terpenylquinones are synthesized by nucleophilic addition or substitution reactions of 1,4-anthracenediones and further transformed into extended polycyclic systems, which mainly keep the 1,4-quinone moiety Fused to different nitrogen- Heterocyclic Rings into the structure.
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new 1 4 anthracenedione derivatives with Fused Heterocyclic Rings synthesis and biological evaluation
RSC Advances, 2015Co-Authors: Ma Angeles Castro, Ana Ma Gamito, Veronica Tangarifecastano, Vicky Roalinares, Jose Miguel M Del Corral, Ana Cecilia Mesaarango, Liliana Betancurgalvis, Andres Francesch, Arturo San FelicianoAbstract:Several terpenylquinones derived from 1,4-anthracenedione (1,4-anthracenequinone, AQ) have been prepared by addition or substitution nucleophilic reactions and further transformed into extended polycyclic systems, which mainly kept the 1,4-quinone moiety Fused to different nitrogen-Heterocyclic Rings (pyrrole, imidazole, pyrazine or quinoxaline) into the structure. The compounds synthesized were evaluated for their antineoplastic, antifungal and antiviral activities. GI50 antineoplastic values remained under μM levels for AQs, while the Heterocyclic derivatives showed antifungal MIC values in the low μg mL−1 range against yeasts and filamentous fungi. Only few compounds displayed a discrete non-selective antiherpetic activity in the μg mL−1 range.
