The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Gordon N Stevenson - One of the best experts on this subject based on the ideXlab platform.
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automated visualization and quantification of spiral artery blood flow entering the first trimester placenta using 3 d power doppler ultrasound
Ultrasound in Medicine and Biology, 2018Co-Authors: Gordon N Stevenson, Alison J Noble, A W Welsh, Lawrence Impey, Sally CollinsAbstract:The goal of our research was to quantify the placental vascularity in 3-D at 11-13 + 6 wk of pregnancy at precise distances from the utero-placental interface (UPI) using 3-D power Doppler ultrasound. With this automated Image analysis technique, differences in vascularity between normal and pathologic pregnancies may be observed. The algorithm was validated using a computer-Generated Image phantom and applied retrospectively in 143 patients. The following features from the PD data were recorded: The number of spiral artery jets into the inter-villous space, total geometric and PD area. These were automatically measured at discrete millimeter distances from the UPI. Differences in features were compared with pregnancy outcomes: Pre-eclamptic versus normal, all small-for-gestational age (SGA) to appropriate-for-gestational age (AGA) patients and AGA versus SGA in normotensives (Mann-Whitney). The Benjamini-Hochberg procedure was used (false discovery rate 10%) for multiple comparison testing. Features decreased with increasing distance from the UPI (Kruskal-Wallis test; p 0.05). This method provides a new in-vivo imaging tool for examining spiral artery development through pregnancy. Size and number of entrances of blood flow into the UPI could potentially be used to identify high-risk pregnancies and may provide a new imaging biomarker for placental insufficiency.
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automated visualization and quantification of spiral artery blood flow entering the first trimester placenta using 3 d power doppler ultrasound
Ultrasound in Medicine and Biology, 2018Co-Authors: Gordon N Stevenson, Alison J Noble, A W Welsh, Lawrence Impey, Sally L CollinsAbstract:To quantify the placental vascularity in 3D at 11–13+6 weeks of pregnancy at precise distances from the utero-placental interface (UPI) using 3D power Doppler (PD) ultrasound. With this automated Image analysis technique, differences in vascularity between normal and pathological pregnancies may be observed. The algorithm was validated using a computer-Generated Image phantom and applied retrospectively in 143 subjects. Scans were conducted with UK (NHS REC) ethical approval. Features from the PD data were recorded, in particular: the number of spiral artery jets into the inter-villous space, total geometric and PD area. These were automatically measured at discrete millimeter distances from the UPI. Differences in features were compared to pregnancy outcomes: pre-eclamptic versus normal, all small-for-gestational (SGA) age to appropriate-for-gestational age (AGA) subjects and AGA versus SGA in normotensives (Mann-Whitney). The Benjamini Hochberg procedure was used (false discovery rate 10%) for multiple comparison testing. Features decreased with increasing distance from the UPI (K-W test; p 0.05). This method provides a new in-vivo imaging tool for examining spiral artery development through pregnancy. Size and number of entrances of blood-flow into the UPI could potentially be used to identify high-risk pregnancies and may provide a new imaging biomarker for placental insufficiency.
Sally Collins - One of the best experts on this subject based on the ideXlab platform.
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automated visualization and quantification of spiral artery blood flow entering the first trimester placenta using 3 d power doppler ultrasound
Ultrasound in Medicine and Biology, 2018Co-Authors: Gordon N Stevenson, Alison J Noble, A W Welsh, Lawrence Impey, Sally CollinsAbstract:The goal of our research was to quantify the placental vascularity in 3-D at 11-13 + 6 wk of pregnancy at precise distances from the utero-placental interface (UPI) using 3-D power Doppler ultrasound. With this automated Image analysis technique, differences in vascularity between normal and pathologic pregnancies may be observed. The algorithm was validated using a computer-Generated Image phantom and applied retrospectively in 143 patients. The following features from the PD data were recorded: The number of spiral artery jets into the inter-villous space, total geometric and PD area. These were automatically measured at discrete millimeter distances from the UPI. Differences in features were compared with pregnancy outcomes: Pre-eclamptic versus normal, all small-for-gestational age (SGA) to appropriate-for-gestational age (AGA) patients and AGA versus SGA in normotensives (Mann-Whitney). The Benjamini-Hochberg procedure was used (false discovery rate 10%) for multiple comparison testing. Features decreased with increasing distance from the UPI (Kruskal-Wallis test; p 0.05). This method provides a new in-vivo imaging tool for examining spiral artery development through pregnancy. Size and number of entrances of blood flow into the UPI could potentially be used to identify high-risk pregnancies and may provide a new imaging biomarker for placental insufficiency.
Sally L Collins - One of the best experts on this subject based on the ideXlab platform.
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automated visualization and quantification of spiral artery blood flow entering the first trimester placenta using 3 d power doppler ultrasound
Ultrasound in Medicine and Biology, 2018Co-Authors: Gordon N Stevenson, Alison J Noble, A W Welsh, Lawrence Impey, Sally L CollinsAbstract:To quantify the placental vascularity in 3D at 11–13+6 weeks of pregnancy at precise distances from the utero-placental interface (UPI) using 3D power Doppler (PD) ultrasound. With this automated Image analysis technique, differences in vascularity between normal and pathological pregnancies may be observed. The algorithm was validated using a computer-Generated Image phantom and applied retrospectively in 143 subjects. Scans were conducted with UK (NHS REC) ethical approval. Features from the PD data were recorded, in particular: the number of spiral artery jets into the inter-villous space, total geometric and PD area. These were automatically measured at discrete millimeter distances from the UPI. Differences in features were compared to pregnancy outcomes: pre-eclamptic versus normal, all small-for-gestational (SGA) age to appropriate-for-gestational age (AGA) subjects and AGA versus SGA in normotensives (Mann-Whitney). The Benjamini Hochberg procedure was used (false discovery rate 10%) for multiple comparison testing. Features decreased with increasing distance from the UPI (K-W test; p 0.05). This method provides a new in-vivo imaging tool for examining spiral artery development through pregnancy. Size and number of entrances of blood-flow into the UPI could potentially be used to identify high-risk pregnancies and may provide a new imaging biomarker for placental insufficiency.
Lawrence Impey - One of the best experts on this subject based on the ideXlab platform.
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automated visualization and quantification of spiral artery blood flow entering the first trimester placenta using 3 d power doppler ultrasound
Ultrasound in Medicine and Biology, 2018Co-Authors: Gordon N Stevenson, Alison J Noble, A W Welsh, Lawrence Impey, Sally CollinsAbstract:The goal of our research was to quantify the placental vascularity in 3-D at 11-13 + 6 wk of pregnancy at precise distances from the utero-placental interface (UPI) using 3-D power Doppler ultrasound. With this automated Image analysis technique, differences in vascularity between normal and pathologic pregnancies may be observed. The algorithm was validated using a computer-Generated Image phantom and applied retrospectively in 143 patients. The following features from the PD data were recorded: The number of spiral artery jets into the inter-villous space, total geometric and PD area. These were automatically measured at discrete millimeter distances from the UPI. Differences in features were compared with pregnancy outcomes: Pre-eclamptic versus normal, all small-for-gestational age (SGA) to appropriate-for-gestational age (AGA) patients and AGA versus SGA in normotensives (Mann-Whitney). The Benjamini-Hochberg procedure was used (false discovery rate 10%) for multiple comparison testing. Features decreased with increasing distance from the UPI (Kruskal-Wallis test; p 0.05). This method provides a new in-vivo imaging tool for examining spiral artery development through pregnancy. Size and number of entrances of blood flow into the UPI could potentially be used to identify high-risk pregnancies and may provide a new imaging biomarker for placental insufficiency.
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automated visualization and quantification of spiral artery blood flow entering the first trimester placenta using 3 d power doppler ultrasound
Ultrasound in Medicine and Biology, 2018Co-Authors: Gordon N Stevenson, Alison J Noble, A W Welsh, Lawrence Impey, Sally L CollinsAbstract:To quantify the placental vascularity in 3D at 11–13+6 weeks of pregnancy at precise distances from the utero-placental interface (UPI) using 3D power Doppler (PD) ultrasound. With this automated Image analysis technique, differences in vascularity between normal and pathological pregnancies may be observed. The algorithm was validated using a computer-Generated Image phantom and applied retrospectively in 143 subjects. Scans were conducted with UK (NHS REC) ethical approval. Features from the PD data were recorded, in particular: the number of spiral artery jets into the inter-villous space, total geometric and PD area. These were automatically measured at discrete millimeter distances from the UPI. Differences in features were compared to pregnancy outcomes: pre-eclamptic versus normal, all small-for-gestational (SGA) age to appropriate-for-gestational age (AGA) subjects and AGA versus SGA in normotensives (Mann-Whitney). The Benjamini Hochberg procedure was used (false discovery rate 10%) for multiple comparison testing. Features decreased with increasing distance from the UPI (K-W test; p 0.05). This method provides a new in-vivo imaging tool for examining spiral artery development through pregnancy. Size and number of entrances of blood-flow into the UPI could potentially be used to identify high-risk pregnancies and may provide a new imaging biomarker for placental insufficiency.
A W Welsh - One of the best experts on this subject based on the ideXlab platform.
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automated visualization and quantification of spiral artery blood flow entering the first trimester placenta using 3 d power doppler ultrasound
Ultrasound in Medicine and Biology, 2018Co-Authors: Gordon N Stevenson, Alison J Noble, A W Welsh, Lawrence Impey, Sally CollinsAbstract:The goal of our research was to quantify the placental vascularity in 3-D at 11-13 + 6 wk of pregnancy at precise distances from the utero-placental interface (UPI) using 3-D power Doppler ultrasound. With this automated Image analysis technique, differences in vascularity between normal and pathologic pregnancies may be observed. The algorithm was validated using a computer-Generated Image phantom and applied retrospectively in 143 patients. The following features from the PD data were recorded: The number of spiral artery jets into the inter-villous space, total geometric and PD area. These were automatically measured at discrete millimeter distances from the UPI. Differences in features were compared with pregnancy outcomes: Pre-eclamptic versus normal, all small-for-gestational age (SGA) to appropriate-for-gestational age (AGA) patients and AGA versus SGA in normotensives (Mann-Whitney). The Benjamini-Hochberg procedure was used (false discovery rate 10%) for multiple comparison testing. Features decreased with increasing distance from the UPI (Kruskal-Wallis test; p 0.05). This method provides a new in-vivo imaging tool for examining spiral artery development through pregnancy. Size and number of entrances of blood flow into the UPI could potentially be used to identify high-risk pregnancies and may provide a new imaging biomarker for placental insufficiency.
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automated visualization and quantification of spiral artery blood flow entering the first trimester placenta using 3 d power doppler ultrasound
Ultrasound in Medicine and Biology, 2018Co-Authors: Gordon N Stevenson, Alison J Noble, A W Welsh, Lawrence Impey, Sally L CollinsAbstract:To quantify the placental vascularity in 3D at 11–13+6 weeks of pregnancy at precise distances from the utero-placental interface (UPI) using 3D power Doppler (PD) ultrasound. With this automated Image analysis technique, differences in vascularity between normal and pathological pregnancies may be observed. The algorithm was validated using a computer-Generated Image phantom and applied retrospectively in 143 subjects. Scans were conducted with UK (NHS REC) ethical approval. Features from the PD data were recorded, in particular: the number of spiral artery jets into the inter-villous space, total geometric and PD area. These were automatically measured at discrete millimeter distances from the UPI. Differences in features were compared to pregnancy outcomes: pre-eclamptic versus normal, all small-for-gestational (SGA) age to appropriate-for-gestational age (AGA) subjects and AGA versus SGA in normotensives (Mann-Whitney). The Benjamini Hochberg procedure was used (false discovery rate 10%) for multiple comparison testing. Features decreased with increasing distance from the UPI (K-W test; p 0.05). This method provides a new in-vivo imaging tool for examining spiral artery development through pregnancy. Size and number of entrances of blood-flow into the UPI could potentially be used to identify high-risk pregnancies and may provide a new imaging biomarker for placental insufficiency.