The Experts below are selected from a list of 100563 Experts worldwide ranked by ideXlab platform
Christoph J Griessenauer - One of the best experts on this subject based on the ideXlab platform.
-
association of renin angiotensin system Genetic Polymorphisms and aneurysmal subarachnoid hemorrhage
Journal of Neurosurgery, 2018Co-Authors: Christoph J Griessenauer, Shane R Tubbs, Paul M Foreman, Michelle H Chua, Nilesh A Vyas, Robert H Lipsky, Ramaswamy K Iyer, Rishikesh Haridas, Beverly C Walters, Salman ChaudryAbstract:OBJECTIVERenin-angiotensin system (RAS) Genetic Polymorphisms are thought to play a role in cerebral aneurysm formation and rupture. The Cerebral Aneurysm Renin-Angiotensin System (CARAS) study prospectively evaluated common RAS Polymorphisms and their relation to aneurysmal subarachnoid hemorrhage (aSAH).METHODSThe CARAS study prospectively enrolled aSAH patients and controls at 2 academic centers in the United States. A blood sample was obtained from all patients for Genetic evaluation and measurement of plasma angiotensin-converting enzyme (ACE) concentration. Common RAS Polymorphisms were detected using 5′ exonuclease (TaqMan) genotyping assays and restriction fragment length polymorphism analysis.RESULTSTwo hundred forty-eight patients were screened, and 149 aSAH patients and 50 controls were available for analysis. There was a recessive effect of the C allele of the angiotensinogen (AGT) C/T single-nucleotide polymorphism (SNP) (OR 1.94, 95% CI 0.912–4.12, p = 0.0853) and a dominant effect of the G ...
-
associations of renin angiotensin system Genetic Polymorphisms and clinical course after aneurysmal subarachnoid hemorrhage
Journal of Neurosurgery, 2017Co-Authors: Christoph J Griessenauer, Shane R Tubbs, Paul M Foreman, Michelle H Chua, Nilesh A Vyas, Robert H Lipsky, Ramaswamy K Iyer, Rishikesh Haridas, Beverly C WaltersAbstract:OBJECTIVERenin-angiotensin system (RAS) Genetic Polymorphisms are thought to play a role in cerebral aneurysm formation and rupture. The Cerebral Aneurysm Renin Angiotensin System (CARAS) study prospectively evaluated associations of common RAS Polymorphisms and clinical course after aneurysmal subarachnoid hemorrhage (aSAH).METHODSThe CARAS study prospectively enrolled aSAH patients at 2 academic centers in the United States. A blood sample was obtained from all patients for Genetic evaluation and measurement of plasma angiotensin converting enzyme (ACE) concentration. Common RAS Polymorphisms were detected using 5′exonuclease genotyping assays and pyrosequencing. Analysis of associations of RAS Polymorphisms and clinical course after aSAH were performed.RESULTSA total of 166 patients were screened, and 149 aSAH patients were included for analysis. A recessive effect of allele I (insertion) of the ACE I/D (insertion/deletion) polymorphism was identified for Hunt and Hess grade in all patients (OR 2.76, 9...
Beverly C Walters - One of the best experts on this subject based on the ideXlab platform.
-
association of renin angiotensin system Genetic Polymorphisms and aneurysmal subarachnoid hemorrhage
Journal of Neurosurgery, 2018Co-Authors: Christoph J Griessenauer, Shane R Tubbs, Paul M Foreman, Michelle H Chua, Nilesh A Vyas, Robert H Lipsky, Ramaswamy K Iyer, Rishikesh Haridas, Beverly C Walters, Salman ChaudryAbstract:OBJECTIVERenin-angiotensin system (RAS) Genetic Polymorphisms are thought to play a role in cerebral aneurysm formation and rupture. The Cerebral Aneurysm Renin-Angiotensin System (CARAS) study prospectively evaluated common RAS Polymorphisms and their relation to aneurysmal subarachnoid hemorrhage (aSAH).METHODSThe CARAS study prospectively enrolled aSAH patients and controls at 2 academic centers in the United States. A blood sample was obtained from all patients for Genetic evaluation and measurement of plasma angiotensin-converting enzyme (ACE) concentration. Common RAS Polymorphisms were detected using 5′ exonuclease (TaqMan) genotyping assays and restriction fragment length polymorphism analysis.RESULTSTwo hundred forty-eight patients were screened, and 149 aSAH patients and 50 controls were available for analysis. There was a recessive effect of the C allele of the angiotensinogen (AGT) C/T single-nucleotide polymorphism (SNP) (OR 1.94, 95% CI 0.912–4.12, p = 0.0853) and a dominant effect of the G ...
-
associations of renin angiotensin system Genetic Polymorphisms and clinical course after aneurysmal subarachnoid hemorrhage
Journal of Neurosurgery, 2017Co-Authors: Christoph J Griessenauer, Shane R Tubbs, Paul M Foreman, Michelle H Chua, Nilesh A Vyas, Robert H Lipsky, Ramaswamy K Iyer, Rishikesh Haridas, Beverly C WaltersAbstract:OBJECTIVERenin-angiotensin system (RAS) Genetic Polymorphisms are thought to play a role in cerebral aneurysm formation and rupture. The Cerebral Aneurysm Renin Angiotensin System (CARAS) study prospectively evaluated associations of common RAS Polymorphisms and clinical course after aneurysmal subarachnoid hemorrhage (aSAH).METHODSThe CARAS study prospectively enrolled aSAH patients at 2 academic centers in the United States. A blood sample was obtained from all patients for Genetic evaluation and measurement of plasma angiotensin converting enzyme (ACE) concentration. Common RAS Polymorphisms were detected using 5′exonuclease genotyping assays and pyrosequencing. Analysis of associations of RAS Polymorphisms and clinical course after aSAH were performed.RESULTSA total of 166 patients were screened, and 149 aSAH patients were included for analysis. A recessive effect of allele I (insertion) of the ACE I/D (insertion/deletion) polymorphism was identified for Hunt and Hess grade in all patients (OR 2.76, 9...
Salman Chaudry - One of the best experts on this subject based on the ideXlab platform.
-
association of renin angiotensin system Genetic Polymorphisms and aneurysmal subarachnoid hemorrhage
Journal of Neurosurgery, 2018Co-Authors: Christoph J Griessenauer, Shane R Tubbs, Paul M Foreman, Michelle H Chua, Nilesh A Vyas, Robert H Lipsky, Ramaswamy K Iyer, Rishikesh Haridas, Beverly C Walters, Salman ChaudryAbstract:OBJECTIVERenin-angiotensin system (RAS) Genetic Polymorphisms are thought to play a role in cerebral aneurysm formation and rupture. The Cerebral Aneurysm Renin-Angiotensin System (CARAS) study prospectively evaluated common RAS Polymorphisms and their relation to aneurysmal subarachnoid hemorrhage (aSAH).METHODSThe CARAS study prospectively enrolled aSAH patients and controls at 2 academic centers in the United States. A blood sample was obtained from all patients for Genetic evaluation and measurement of plasma angiotensin-converting enzyme (ACE) concentration. Common RAS Polymorphisms were detected using 5′ exonuclease (TaqMan) genotyping assays and restriction fragment length polymorphism analysis.RESULTSTwo hundred forty-eight patients were screened, and 149 aSAH patients and 50 controls were available for analysis. There was a recessive effect of the C allele of the angiotensinogen (AGT) C/T single-nucleotide polymorphism (SNP) (OR 1.94, 95% CI 0.912–4.12, p = 0.0853) and a dominant effect of the G ...
Alejandro de la De La Sierra - One of the best experts on this subject based on the ideXlab platform.
-
Renin-angiotensin system Genetic Polymorphisms and salt sensitivity in essential hypertension.
Hypertension, 2000Co-Authors: Vicente Giner, Ernesto Bragulat, Josep Oriola, Esteban Poch, Antonio Coca, Alejandro de la De La SierraAbstract:We evaluated the association between salt-sensitive hypertension and 3 different Genetic Polymorphisms of the renin-angiotensin system. Fifty patients with essential hypertension were classified as salt sensitive or salt resistant, depending on the presence or absence of a significant increase (P
Paul M Foreman - One of the best experts on this subject based on the ideXlab platform.
-
association of renin angiotensin system Genetic Polymorphisms and aneurysmal subarachnoid hemorrhage
Journal of Neurosurgery, 2018Co-Authors: Christoph J Griessenauer, Shane R Tubbs, Paul M Foreman, Michelle H Chua, Nilesh A Vyas, Robert H Lipsky, Ramaswamy K Iyer, Rishikesh Haridas, Beverly C Walters, Salman ChaudryAbstract:OBJECTIVERenin-angiotensin system (RAS) Genetic Polymorphisms are thought to play a role in cerebral aneurysm formation and rupture. The Cerebral Aneurysm Renin-Angiotensin System (CARAS) study prospectively evaluated common RAS Polymorphisms and their relation to aneurysmal subarachnoid hemorrhage (aSAH).METHODSThe CARAS study prospectively enrolled aSAH patients and controls at 2 academic centers in the United States. A blood sample was obtained from all patients for Genetic evaluation and measurement of plasma angiotensin-converting enzyme (ACE) concentration. Common RAS Polymorphisms were detected using 5′ exonuclease (TaqMan) genotyping assays and restriction fragment length polymorphism analysis.RESULTSTwo hundred forty-eight patients were screened, and 149 aSAH patients and 50 controls were available for analysis. There was a recessive effect of the C allele of the angiotensinogen (AGT) C/T single-nucleotide polymorphism (SNP) (OR 1.94, 95% CI 0.912–4.12, p = 0.0853) and a dominant effect of the G ...
-
associations of renin angiotensin system Genetic Polymorphisms and clinical course after aneurysmal subarachnoid hemorrhage
Journal of Neurosurgery, 2017Co-Authors: Christoph J Griessenauer, Shane R Tubbs, Paul M Foreman, Michelle H Chua, Nilesh A Vyas, Robert H Lipsky, Ramaswamy K Iyer, Rishikesh Haridas, Beverly C WaltersAbstract:OBJECTIVERenin-angiotensin system (RAS) Genetic Polymorphisms are thought to play a role in cerebral aneurysm formation and rupture. The Cerebral Aneurysm Renin Angiotensin System (CARAS) study prospectively evaluated associations of common RAS Polymorphisms and clinical course after aneurysmal subarachnoid hemorrhage (aSAH).METHODSThe CARAS study prospectively enrolled aSAH patients at 2 academic centers in the United States. A blood sample was obtained from all patients for Genetic evaluation and measurement of plasma angiotensin converting enzyme (ACE) concentration. Common RAS Polymorphisms were detected using 5′exonuclease genotyping assays and pyrosequencing. Analysis of associations of RAS Polymorphisms and clinical course after aSAH were performed.RESULTSA total of 166 patients were screened, and 149 aSAH patients were included for analysis. A recessive effect of allele I (insertion) of the ACE I/D (insertion/deletion) polymorphism was identified for Hunt and Hess grade in all patients (OR 2.76, 9...