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Jorge Marcet - One of the best experts on this subject based on the ideXlab platform.

  • Squamous-cell carcinoma of the pelvis in a Giant Condyloma Acuminatum: Use of neoadjuvant chemoradiation and surgical resection
    Diseases of the Colon & Rectum, 1998
    Co-Authors: Micheline Hyacinthe, Richard Karl, Domenico Coppola, Thomas Goodgame, William Redwood, Paul Goldenfarb, N. Paul Ohori, Jorge Marcet
    Abstract:

    A 60-year-old bisexual male was referred to our institution for management of an unresectable squamous-cell carcinoma of the pelvis arising in a Giant Condyloma Acuminatum. He received neoadjuvant chemoradiation consisting of 5-fluorouracil and mitomycin C with concurrent external beam radiation, followed by posterior pelvic exenteration. The surgical specimen had no residual cancer. In situ hybridization was performed using a human papilloma virus omniprobe for human papilloma virus subtypes 6, 11, 16, 18, 31, 33, and 35. Two years after diagnosis the patient is doing well with no evidence of recurrent disease.

  • Squamous-cell carcinoma of the pelvis in a Giant Condyloma Acuminatum : Use of neoadjuvant chemoradiation and surgical resection : Report of a case
    Diseases of the colon and rectum, 1998
    Co-Authors: Micheline Hyacinthe, Domenico Coppola, Thomas Goodgame, William Redwood, Paul Goldenfarb, N. Paul Ohori, Richard C. Karl, Jorge Marcet
    Abstract:

    A 60-year-old bisexual male was referred to our institution for management of an unresectable squamous-cell carcinoma of the pelvis arising in a Giant Condyloma Acuminatum. He received neoadjuvant chemoradiation consisting of 5-fluorouracil and mitomycin C with concurrent external beam radiation, followed by posterior pelvic exenteration. The surgical specimen had no residual cancer. In situ hybridization was performed using a human papilloma virus omniprobe for human papilloma virus subtypes 6, 11, 16, 18, 31, 33, and 35. Two years after diagnosis the patient is doing well with no evidence of recurrent disease.

Yi Zhan - One of the best experts on this subject based on the ideXlab platform.

Micheline Hyacinthe - One of the best experts on this subject based on the ideXlab platform.

  • Squamous-cell carcinoma of the pelvis in a Giant Condyloma Acuminatum: Use of neoadjuvant chemoradiation and surgical resection
    Diseases of the Colon & Rectum, 1998
    Co-Authors: Micheline Hyacinthe, Richard Karl, Domenico Coppola, Thomas Goodgame, William Redwood, Paul Goldenfarb, N. Paul Ohori, Jorge Marcet
    Abstract:

    A 60-year-old bisexual male was referred to our institution for management of an unresectable squamous-cell carcinoma of the pelvis arising in a Giant Condyloma Acuminatum. He received neoadjuvant chemoradiation consisting of 5-fluorouracil and mitomycin C with concurrent external beam radiation, followed by posterior pelvic exenteration. The surgical specimen had no residual cancer. In situ hybridization was performed using a human papilloma virus omniprobe for human papilloma virus subtypes 6, 11, 16, 18, 31, 33, and 35. Two years after diagnosis the patient is doing well with no evidence of recurrent disease.

  • Squamous-cell carcinoma of the pelvis in a Giant Condyloma Acuminatum : Use of neoadjuvant chemoradiation and surgical resection : Report of a case
    Diseases of the colon and rectum, 1998
    Co-Authors: Micheline Hyacinthe, Domenico Coppola, Thomas Goodgame, William Redwood, Paul Goldenfarb, N. Paul Ohori, Richard C. Karl, Jorge Marcet
    Abstract:

    A 60-year-old bisexual male was referred to our institution for management of an unresectable squamous-cell carcinoma of the pelvis arising in a Giant Condyloma Acuminatum. He received neoadjuvant chemoradiation consisting of 5-fluorouracil and mitomycin C with concurrent external beam radiation, followed by posterior pelvic exenteration. The surgical specimen had no residual cancer. In situ hybridization was performed using a human papilloma virus omniprobe for human papilloma virus subtypes 6, 11, 16, 18, 31, 33, and 35. Two years after diagnosis the patient is doing well with no evidence of recurrent disease.

Xiufang Chen - One of the best experts on this subject based on the ideXlab platform.

Arturo P Saavedra - One of the best experts on this subject based on the ideXlab platform.

  • Successful treatment of perianal Giant Condyloma Acuminatum in an immunocompromised host with systemic interleukin 2 and topical cidofovir.
    JAMA Dermatology, 2013
    Co-Authors: Vinod E Nambudiri, Kudakwashe K. Mutyambizi, Andrew C. Walls, David C. Fisher, Ronald Bleday, Arturo P Saavedra
    Abstract:

    A 46-year-old man presented for evaluation of large recurrent growths around the anus and rectum. He had been diagnosed as having chronic lymphocytic leukemia at age 36 years and was treated with fludarabine phosphate, cyclophosphamide, and rituximab at age 42 years, with successful induction of remission. His disease returned 3 years later, and while undergoing chemotherapy with the same regimen, he developed perianal and penile skin lesions. The penile lesions cleared with serial treatment with cryotherapy, imiquimod, and sinecatechins, to which the perianal lesions were refractory. He underwent 2 surgical debulking procedures for the rapidly progressive perianal lesions, which exhibited aggressive regrowth within 2 weeks of each debulking. Physical examination revealed a large (>10 cm in diameter), circumferential (but not occluding the rectum), exophytic, friable perianal mass with punctate bleeding, consistent with Giant Condyloma Acuminatum (GCA). An adjacent 3-mm papule with corymbiform surface consistent with a common wart was also noted (Figure 1). The patient reported considerable rectal pain and bleeding due to the anal Condyloma. The perianal mass demonstrated severe squamous dysplasia, with focal areas concerning for squamous cell carcinoma in situ on histopathologic examination. The remaining findings from examination were unremarkable.