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M Chen - One of the best experts on this subject based on the ideXlab platform.
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impacts of Glycemic Control on intracranial plaque in patients with type 2 diabetes mellitus a vessel wall mri study
American Journal of Neuroradiology, 2021Co-Authors: S Jiao, J Huang, Y Chen, Y Song, T Gong, T Guo, Jianhua Zhang, C Zhang, M ChenAbstract:BACKGROUND AND PURPOSE The relationship between Glycemic Control in patients with type 2 diabetes mellitus and intracranial atherosclerotic plaque features has remained understudied. This study aimed to investigate the association of type 2 diabetes mellitus and Glycemic Control with the characteristics of intracranial plaques using vessel wall MR imaging. MATERIALS AND METHODS In total, 311 patients (217 [69.8%] men; mean age, 63.24 ± 11.44 years) with intracranial atherosclerotic plaques detected on vessel wall MR imaging were enrolled and divided into 3 groups according to type 2 diabetes mellitus and Glycemic Control statuses: the non-type 2 diabetes mellitus group, the type 2 diabetes mellitus with good Glycemic Control group, and the type 2 diabetes mellitus with poor Glycemic Control group. The imaging features of intracranial plaque were analyzed and compared among the groups. The clinical risk factors for atherosclerosis were also analyzed using logistic regression analysis. RESULTS The plaque length and thickness were significantly higher in the type 2 diabetes mellitus with poor Glycemic Control group than in the non-type 2 diabetes mellitus group. The prevalence of strongly enhanced plaques was significantly higher in the type 2 diabetes mellitus with poor Glycemic Control group than in the non-type 2 diabetes mellitus and type 2 diabetes mellitus with good Glycemic Control groups (92.9%, 63.4%, and 72.7%, respectively; P < .001). Multivariate logistic regression analysis showed a significant association of poor Glycemic Control with the plaque length (OR = 1.966; 95% CI, 1.170-3.303; P = .011), plaque thickness (OR = 1.981; 95% CI, 1.174-3.340; P = .010), and strongly enhanced plaque (OR = 5.448; 95% CI, 2.385-12.444; P < .001). CONCLUSIONS Poor Glycemic Control, compared with the history of diabetes, might have a greater impact on the burden and vulnerability of intracranial atherosclerotic plaques.
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impacts of Glycemic Control on intracranial plaque in patients with type 2 diabetes mellitus a vessel wall mri study
American Journal of Neuroradiology, 2021Co-Authors: S Jiao, J Huang, Y Chen, Y Song, T Gong, T Guo, Jianhua Zhang, C Zhang, M ChenAbstract:BACKGROUND AND PURPOSE: The relationship between Glycemic Control in patients with type 2 diabetes mellitus and intracranial atherosclerotic plaque features has remained understudied. This study aimed to investigate the association of type 2 diabetes mellitus and Glycemic Control with the characteristics of intracranial plaques using vessel wall MR imaging. MATERIALS AND METHODS: In total, 311 patients (217 [69.8%] men; mean age, 63.24 ± 11.44 years) with intracranial atherosclerotic plaques detected on vessel wall MR imaging were enrolled and divided into 3 groups according to type 2 diabetes mellitus and Glycemic Control statuses: the non-type 2 diabetes mellitus group, the type 2 diabetes mellitus with good Glycemic Control group, and the type 2 diabetes mellitus with poor Glycemic Control group. The imaging features of intracranial plaque were analyzed and compared among the groups. The clinical risk factors for atherosclerosis were also analyzed using logistic regression analysis. RESULTS: The plaque length and thickness were significantly higher in the type 2 diabetes mellitus with poor Glycemic Control group than in the non-type 2 diabetes mellitus group. The prevalence of strongly enhanced plaques was significantly higher in the type 2 diabetes mellitus with poor Glycemic Control group than in the non-type 2 diabetes mellitus and type 2 diabetes mellitus with good Glycemic Control groups (92.9%, 63.4%, and 72.7%, respectively; P CONCLUSIONS: Poor Glycemic Control, compared with the history of diabetes, might have a greater impact on the burden and vulnerability of intracranial atherosclerotic plaques.
S Jiao - One of the best experts on this subject based on the ideXlab platform.
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impacts of Glycemic Control on intracranial plaque in patients with type 2 diabetes mellitus a vessel wall mri study
American Journal of Neuroradiology, 2021Co-Authors: S Jiao, J Huang, Y Chen, Y Song, T Gong, T Guo, Jianhua Zhang, C Zhang, M ChenAbstract:BACKGROUND AND PURPOSE The relationship between Glycemic Control in patients with type 2 diabetes mellitus and intracranial atherosclerotic plaque features has remained understudied. This study aimed to investigate the association of type 2 diabetes mellitus and Glycemic Control with the characteristics of intracranial plaques using vessel wall MR imaging. MATERIALS AND METHODS In total, 311 patients (217 [69.8%] men; mean age, 63.24 ± 11.44 years) with intracranial atherosclerotic plaques detected on vessel wall MR imaging were enrolled and divided into 3 groups according to type 2 diabetes mellitus and Glycemic Control statuses: the non-type 2 diabetes mellitus group, the type 2 diabetes mellitus with good Glycemic Control group, and the type 2 diabetes mellitus with poor Glycemic Control group. The imaging features of intracranial plaque were analyzed and compared among the groups. The clinical risk factors for atherosclerosis were also analyzed using logistic regression analysis. RESULTS The plaque length and thickness were significantly higher in the type 2 diabetes mellitus with poor Glycemic Control group than in the non-type 2 diabetes mellitus group. The prevalence of strongly enhanced plaques was significantly higher in the type 2 diabetes mellitus with poor Glycemic Control group than in the non-type 2 diabetes mellitus and type 2 diabetes mellitus with good Glycemic Control groups (92.9%, 63.4%, and 72.7%, respectively; P < .001). Multivariate logistic regression analysis showed a significant association of poor Glycemic Control with the plaque length (OR = 1.966; 95% CI, 1.170-3.303; P = .011), plaque thickness (OR = 1.981; 95% CI, 1.174-3.340; P = .010), and strongly enhanced plaque (OR = 5.448; 95% CI, 2.385-12.444; P < .001). CONCLUSIONS Poor Glycemic Control, compared with the history of diabetes, might have a greater impact on the burden and vulnerability of intracranial atherosclerotic plaques.
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impacts of Glycemic Control on intracranial plaque in patients with type 2 diabetes mellitus a vessel wall mri study
American Journal of Neuroradiology, 2021Co-Authors: S Jiao, J Huang, Y Chen, Y Song, T Gong, T Guo, Jianhua Zhang, C Zhang, M ChenAbstract:BACKGROUND AND PURPOSE: The relationship between Glycemic Control in patients with type 2 diabetes mellitus and intracranial atherosclerotic plaque features has remained understudied. This study aimed to investigate the association of type 2 diabetes mellitus and Glycemic Control with the characteristics of intracranial plaques using vessel wall MR imaging. MATERIALS AND METHODS: In total, 311 patients (217 [69.8%] men; mean age, 63.24 ± 11.44 years) with intracranial atherosclerotic plaques detected on vessel wall MR imaging were enrolled and divided into 3 groups according to type 2 diabetes mellitus and Glycemic Control statuses: the non-type 2 diabetes mellitus group, the type 2 diabetes mellitus with good Glycemic Control group, and the type 2 diabetes mellitus with poor Glycemic Control group. The imaging features of intracranial plaque were analyzed and compared among the groups. The clinical risk factors for atherosclerosis were also analyzed using logistic regression analysis. RESULTS: The plaque length and thickness were significantly higher in the type 2 diabetes mellitus with poor Glycemic Control group than in the non-type 2 diabetes mellitus group. The prevalence of strongly enhanced plaques was significantly higher in the type 2 diabetes mellitus with poor Glycemic Control group than in the non-type 2 diabetes mellitus and type 2 diabetes mellitus with good Glycemic Control groups (92.9%, 63.4%, and 72.7%, respectively; P CONCLUSIONS: Poor Glycemic Control, compared with the history of diabetes, might have a greater impact on the burden and vulnerability of intracranial atherosclerotic plaques.
Jenqwen Huang - One of the best experts on this subject based on the ideXlab platform.
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glycosylated hemoglobin and albumin corrected fructosamine are good indicators for Glycemic Control in peritoneal dialysis patients
PLOS ONE, 2013Co-Authors: Szuying Lee, Yincheng Chen, Ichieh Tsai, Chungjen Yen, Shuneng Chueh, Hsuehfang Chuang, Chihkang Chiang, Huiteng Cheng, Kuanyu Hung, Jenqwen HuangAbstract:Purpose Diabetes mellitus (DM) is the most common cause of end-stage renal disease and is an important risk factor for morbidity and mortality after dialysis. However, Glycemic Control among such patients is difficult to assess. The present study examined Glycemic Control parameters and observed glucose variation after refilling different kinds of fresh dialysate in peritoneal dialysis (PD) patients. Methods A total of 25 DM PD patients were recruited, and continuous glucose monitoring system (CGMS) was applied to measure interstitial fluid (ISF) glucose levels at 5-min intervals for 3 days. Patients filled out diet and PD fluid exchange diaries. The records measured with CGMS were analyzed and correlated with other Glycemic Control parameters such as fructosamine, albumin-corrected fructosamine (AlbF), glycosylated hemoglobin (HbA1c), and glycated albumin levels. Results There were significant correlations between mean ISF glucose and fructosamine (r = 0.45, P<0.05), AlbF (r = 0.54, P<0.01), and HbA1c (r = 0.51, P<0.01). The ISF glucose levels in glucose-containing dialysate increased from approximately 7–8 mg/dL within 1 hour of exchange in contrast to icodextrin dialysate which kept ISF glucose levels unchanged. Conclusion HbA1c and AlbF significantly correlated with the mean ISF glucose levels, indicating that they are reliable indices of Glycemic Control in DM PD patients. Icodextrin dialysate seems to have a favorable Glycemic Control effect when compared to the other glucose-containing dialysates.
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glycosylated hemoglobin and albumin corrected fructosamine are good indicators for Glycemic Control in peritoneal dialysis patients
PLOS ONE, 2013Co-Authors: Szuying Lee, Yincheng Chen, Ichieh Tsai, Chungjen Yen, Shuneng Chueh, Hsuehfang Chuang, Chihkang Chiang, Huiteng Cheng, Kuanyu Hung, Jenqwen HuangAbstract:Purpose Diabetes mellitus (DM) is the most common cause of end-stage renal disease and is an important risk factor for morbidity and mortality after dialysis. However, Glycemic Control among such patients is difficult to assess. The present study examined Glycemic Control parameters and observed glucose variation after refilling different kinds of fresh dialysate in peritoneal dialysis (PD) patients.
C Zhang - One of the best experts on this subject based on the ideXlab platform.
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impacts of Glycemic Control on intracranial plaque in patients with type 2 diabetes mellitus a vessel wall mri study
American Journal of Neuroradiology, 2021Co-Authors: S Jiao, J Huang, Y Chen, Y Song, T Gong, T Guo, Jianhua Zhang, C Zhang, M ChenAbstract:BACKGROUND AND PURPOSE The relationship between Glycemic Control in patients with type 2 diabetes mellitus and intracranial atherosclerotic plaque features has remained understudied. This study aimed to investigate the association of type 2 diabetes mellitus and Glycemic Control with the characteristics of intracranial plaques using vessel wall MR imaging. MATERIALS AND METHODS In total, 311 patients (217 [69.8%] men; mean age, 63.24 ± 11.44 years) with intracranial atherosclerotic plaques detected on vessel wall MR imaging were enrolled and divided into 3 groups according to type 2 diabetes mellitus and Glycemic Control statuses: the non-type 2 diabetes mellitus group, the type 2 diabetes mellitus with good Glycemic Control group, and the type 2 diabetes mellitus with poor Glycemic Control group. The imaging features of intracranial plaque were analyzed and compared among the groups. The clinical risk factors for atherosclerosis were also analyzed using logistic regression analysis. RESULTS The plaque length and thickness were significantly higher in the type 2 diabetes mellitus with poor Glycemic Control group than in the non-type 2 diabetes mellitus group. The prevalence of strongly enhanced plaques was significantly higher in the type 2 diabetes mellitus with poor Glycemic Control group than in the non-type 2 diabetes mellitus and type 2 diabetes mellitus with good Glycemic Control groups (92.9%, 63.4%, and 72.7%, respectively; P < .001). Multivariate logistic regression analysis showed a significant association of poor Glycemic Control with the plaque length (OR = 1.966; 95% CI, 1.170-3.303; P = .011), plaque thickness (OR = 1.981; 95% CI, 1.174-3.340; P = .010), and strongly enhanced plaque (OR = 5.448; 95% CI, 2.385-12.444; P < .001). CONCLUSIONS Poor Glycemic Control, compared with the history of diabetes, might have a greater impact on the burden and vulnerability of intracranial atherosclerotic plaques.
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impacts of Glycemic Control on intracranial plaque in patients with type 2 diabetes mellitus a vessel wall mri study
American Journal of Neuroradiology, 2021Co-Authors: S Jiao, J Huang, Y Chen, Y Song, T Gong, T Guo, Jianhua Zhang, C Zhang, M ChenAbstract:BACKGROUND AND PURPOSE: The relationship between Glycemic Control in patients with type 2 diabetes mellitus and intracranial atherosclerotic plaque features has remained understudied. This study aimed to investigate the association of type 2 diabetes mellitus and Glycemic Control with the characteristics of intracranial plaques using vessel wall MR imaging. MATERIALS AND METHODS: In total, 311 patients (217 [69.8%] men; mean age, 63.24 ± 11.44 years) with intracranial atherosclerotic plaques detected on vessel wall MR imaging were enrolled and divided into 3 groups according to type 2 diabetes mellitus and Glycemic Control statuses: the non-type 2 diabetes mellitus group, the type 2 diabetes mellitus with good Glycemic Control group, and the type 2 diabetes mellitus with poor Glycemic Control group. The imaging features of intracranial plaque were analyzed and compared among the groups. The clinical risk factors for atherosclerosis were also analyzed using logistic regression analysis. RESULTS: The plaque length and thickness were significantly higher in the type 2 diabetes mellitus with poor Glycemic Control group than in the non-type 2 diabetes mellitus group. The prevalence of strongly enhanced plaques was significantly higher in the type 2 diabetes mellitus with poor Glycemic Control group than in the non-type 2 diabetes mellitus and type 2 diabetes mellitus with good Glycemic Control groups (92.9%, 63.4%, and 72.7%, respectively; P CONCLUSIONS: Poor Glycemic Control, compared with the history of diabetes, might have a greater impact on the burden and vulnerability of intracranial atherosclerotic plaques.
Jianhua Zhang - One of the best experts on this subject based on the ideXlab platform.
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impacts of Glycemic Control on intracranial plaque in patients with type 2 diabetes mellitus a vessel wall mri study
American Journal of Neuroradiology, 2021Co-Authors: S Jiao, J Huang, Y Chen, Y Song, T Gong, T Guo, Jianhua Zhang, C Zhang, M ChenAbstract:BACKGROUND AND PURPOSE The relationship between Glycemic Control in patients with type 2 diabetes mellitus and intracranial atherosclerotic plaque features has remained understudied. This study aimed to investigate the association of type 2 diabetes mellitus and Glycemic Control with the characteristics of intracranial plaques using vessel wall MR imaging. MATERIALS AND METHODS In total, 311 patients (217 [69.8%] men; mean age, 63.24 ± 11.44 years) with intracranial atherosclerotic plaques detected on vessel wall MR imaging were enrolled and divided into 3 groups according to type 2 diabetes mellitus and Glycemic Control statuses: the non-type 2 diabetes mellitus group, the type 2 diabetes mellitus with good Glycemic Control group, and the type 2 diabetes mellitus with poor Glycemic Control group. The imaging features of intracranial plaque were analyzed and compared among the groups. The clinical risk factors for atherosclerosis were also analyzed using logistic regression analysis. RESULTS The plaque length and thickness were significantly higher in the type 2 diabetes mellitus with poor Glycemic Control group than in the non-type 2 diabetes mellitus group. The prevalence of strongly enhanced plaques was significantly higher in the type 2 diabetes mellitus with poor Glycemic Control group than in the non-type 2 diabetes mellitus and type 2 diabetes mellitus with good Glycemic Control groups (92.9%, 63.4%, and 72.7%, respectively; P < .001). Multivariate logistic regression analysis showed a significant association of poor Glycemic Control with the plaque length (OR = 1.966; 95% CI, 1.170-3.303; P = .011), plaque thickness (OR = 1.981; 95% CI, 1.174-3.340; P = .010), and strongly enhanced plaque (OR = 5.448; 95% CI, 2.385-12.444; P < .001). CONCLUSIONS Poor Glycemic Control, compared with the history of diabetes, might have a greater impact on the burden and vulnerability of intracranial atherosclerotic plaques.
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impacts of Glycemic Control on intracranial plaque in patients with type 2 diabetes mellitus a vessel wall mri study
American Journal of Neuroradiology, 2021Co-Authors: S Jiao, J Huang, Y Chen, Y Song, T Gong, T Guo, Jianhua Zhang, C Zhang, M ChenAbstract:BACKGROUND AND PURPOSE: The relationship between Glycemic Control in patients with type 2 diabetes mellitus and intracranial atherosclerotic plaque features has remained understudied. This study aimed to investigate the association of type 2 diabetes mellitus and Glycemic Control with the characteristics of intracranial plaques using vessel wall MR imaging. MATERIALS AND METHODS: In total, 311 patients (217 [69.8%] men; mean age, 63.24 ± 11.44 years) with intracranial atherosclerotic plaques detected on vessel wall MR imaging were enrolled and divided into 3 groups according to type 2 diabetes mellitus and Glycemic Control statuses: the non-type 2 diabetes mellitus group, the type 2 diabetes mellitus with good Glycemic Control group, and the type 2 diabetes mellitus with poor Glycemic Control group. The imaging features of intracranial plaque were analyzed and compared among the groups. The clinical risk factors for atherosclerosis were also analyzed using logistic regression analysis. RESULTS: The plaque length and thickness were significantly higher in the type 2 diabetes mellitus with poor Glycemic Control group than in the non-type 2 diabetes mellitus group. The prevalence of strongly enhanced plaques was significantly higher in the type 2 diabetes mellitus with poor Glycemic Control group than in the non-type 2 diabetes mellitus and type 2 diabetes mellitus with good Glycemic Control groups (92.9%, 63.4%, and 72.7%, respectively; P CONCLUSIONS: Poor Glycemic Control, compared with the history of diabetes, might have a greater impact on the burden and vulnerability of intracranial atherosclerotic plaques.