The Experts below are selected from a list of 105 Experts worldwide ranked by ideXlab platform
Nina Kann - One of the best experts on this subject based on the ideXlab platform.
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Glycerol upgrading via hydrogen borrowing direct ruthenium catalyzed amination of the Glycerol Derivative solketal
ACS Sustainable Chemistry & Engineering, 2016Co-Authors: Anna Said Stalsmeden, Jose Luis Belmonte Vazquez, Kim Van Weerdenburg, Rebecca Rae, Perola Norrby, Nina KannAbstract:Hydrogen borrowing provides an efficient and atom economical method for carbon–nitrogen and carbon–carbon bond formation from alcohol precursors. Glycerol is a renewable nontoxic polyol and a potential precursor to small functional organic molecules. We here report the direct amination of solketal, a 1,2-hydroxy-protected Derivative of Glycerol, via ruthenium-catalyzed hydrogen borrowing, affording up to 99% conversion and 92% isolated yield using [Ru(p-cymene)Cl2]2 as the catalyst precursor. The synthesis of an antitussive agent in 86% overall yield from solketal was also demonstrated using this methodology.
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Glycerol Upgrading via Hydrogen Borrowing: Direct Ruthenium-Catalyzed Amination of the Glycerol Derivative Solketal
2016Co-Authors: Anna Said Stålsmeden, Kim Van Weerdenburg, Rebecca Rae, Perola Norrby, José Luis Belmonte Vázquez, Nina KannAbstract:Hydrogen borrowing provides an efficient and atom economical method for carbon–nitrogen and carbon–carbon bond formation from alcohol precursors. Glycerol is a renewable nontoxic polyol and a potential precursor to small functional organic molecules. We here report the direct amination of solketal, a 1,2-hydroxy-protected Derivative of Glycerol, via ruthenium-catalyzed hydrogen borrowing, affording up to 99% conversion and 92% isolated yield using [Ru(p-cymene)Cl2]2 as the catalyst precursor. The synthesis of an antitussive agent in 86% overall yield from solketal was also demonstrated using this methodology
Anna Said Stalsmeden - One of the best experts on this subject based on the ideXlab platform.
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Glycerol upgrading via hydrogen borrowing direct ruthenium catalyzed amination of the Glycerol Derivative solketal
ACS Sustainable Chemistry & Engineering, 2016Co-Authors: Anna Said Stalsmeden, Jose Luis Belmonte Vazquez, Kim Van Weerdenburg, Rebecca Rae, Perola Norrby, Nina KannAbstract:Hydrogen borrowing provides an efficient and atom economical method for carbon–nitrogen and carbon–carbon bond formation from alcohol precursors. Glycerol is a renewable nontoxic polyol and a potential precursor to small functional organic molecules. We here report the direct amination of solketal, a 1,2-hydroxy-protected Derivative of Glycerol, via ruthenium-catalyzed hydrogen borrowing, affording up to 99% conversion and 92% isolated yield using [Ru(p-cymene)Cl2]2 as the catalyst precursor. The synthesis of an antitussive agent in 86% overall yield from solketal was also demonstrated using this methodology.
Kim Van Weerdenburg - One of the best experts on this subject based on the ideXlab platform.
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Glycerol upgrading via hydrogen borrowing direct ruthenium catalyzed amination of the Glycerol Derivative solketal
ACS Sustainable Chemistry & Engineering, 2016Co-Authors: Anna Said Stalsmeden, Jose Luis Belmonte Vazquez, Kim Van Weerdenburg, Rebecca Rae, Perola Norrby, Nina KannAbstract:Hydrogen borrowing provides an efficient and atom economical method for carbon–nitrogen and carbon–carbon bond formation from alcohol precursors. Glycerol is a renewable nontoxic polyol and a potential precursor to small functional organic molecules. We here report the direct amination of solketal, a 1,2-hydroxy-protected Derivative of Glycerol, via ruthenium-catalyzed hydrogen borrowing, affording up to 99% conversion and 92% isolated yield using [Ru(p-cymene)Cl2]2 as the catalyst precursor. The synthesis of an antitussive agent in 86% overall yield from solketal was also demonstrated using this methodology.
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Glycerol Upgrading via Hydrogen Borrowing: Direct Ruthenium-Catalyzed Amination of the Glycerol Derivative Solketal
2016Co-Authors: Anna Said Stålsmeden, Kim Van Weerdenburg, Rebecca Rae, Perola Norrby, José Luis Belmonte Vázquez, Nina KannAbstract:Hydrogen borrowing provides an efficient and atom economical method for carbon–nitrogen and carbon–carbon bond formation from alcohol precursors. Glycerol is a renewable nontoxic polyol and a potential precursor to small functional organic molecules. We here report the direct amination of solketal, a 1,2-hydroxy-protected Derivative of Glycerol, via ruthenium-catalyzed hydrogen borrowing, affording up to 99% conversion and 92% isolated yield using [Ru(p-cymene)Cl2]2 as the catalyst precursor. The synthesis of an antitussive agent in 86% overall yield from solketal was also demonstrated using this methodology
Rebecca Rae - One of the best experts on this subject based on the ideXlab platform.
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Glycerol upgrading via hydrogen borrowing direct ruthenium catalyzed amination of the Glycerol Derivative solketal
ACS Sustainable Chemistry & Engineering, 2016Co-Authors: Anna Said Stalsmeden, Jose Luis Belmonte Vazquez, Kim Van Weerdenburg, Rebecca Rae, Perola Norrby, Nina KannAbstract:Hydrogen borrowing provides an efficient and atom economical method for carbon–nitrogen and carbon–carbon bond formation from alcohol precursors. Glycerol is a renewable nontoxic polyol and a potential precursor to small functional organic molecules. We here report the direct amination of solketal, a 1,2-hydroxy-protected Derivative of Glycerol, via ruthenium-catalyzed hydrogen borrowing, affording up to 99% conversion and 92% isolated yield using [Ru(p-cymene)Cl2]2 as the catalyst precursor. The synthesis of an antitussive agent in 86% overall yield from solketal was also demonstrated using this methodology.
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Glycerol Upgrading via Hydrogen Borrowing: Direct Ruthenium-Catalyzed Amination of the Glycerol Derivative Solketal
2016Co-Authors: Anna Said Stålsmeden, Kim Van Weerdenburg, Rebecca Rae, Perola Norrby, José Luis Belmonte Vázquez, Nina KannAbstract:Hydrogen borrowing provides an efficient and atom economical method for carbon–nitrogen and carbon–carbon bond formation from alcohol precursors. Glycerol is a renewable nontoxic polyol and a potential precursor to small functional organic molecules. We here report the direct amination of solketal, a 1,2-hydroxy-protected Derivative of Glycerol, via ruthenium-catalyzed hydrogen borrowing, affording up to 99% conversion and 92% isolated yield using [Ru(p-cymene)Cl2]2 as the catalyst precursor. The synthesis of an antitussive agent in 86% overall yield from solketal was also demonstrated using this methodology
Perola Norrby - One of the best experts on this subject based on the ideXlab platform.
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Glycerol upgrading via hydrogen borrowing direct ruthenium catalyzed amination of the Glycerol Derivative solketal
ACS Sustainable Chemistry & Engineering, 2016Co-Authors: Anna Said Stalsmeden, Jose Luis Belmonte Vazquez, Kim Van Weerdenburg, Rebecca Rae, Perola Norrby, Nina KannAbstract:Hydrogen borrowing provides an efficient and atom economical method for carbon–nitrogen and carbon–carbon bond formation from alcohol precursors. Glycerol is a renewable nontoxic polyol and a potential precursor to small functional organic molecules. We here report the direct amination of solketal, a 1,2-hydroxy-protected Derivative of Glycerol, via ruthenium-catalyzed hydrogen borrowing, affording up to 99% conversion and 92% isolated yield using [Ru(p-cymene)Cl2]2 as the catalyst precursor. The synthesis of an antitussive agent in 86% overall yield from solketal was also demonstrated using this methodology.
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Glycerol Upgrading via Hydrogen Borrowing: Direct Ruthenium-Catalyzed Amination of the Glycerol Derivative Solketal
2016Co-Authors: Anna Said Stålsmeden, Kim Van Weerdenburg, Rebecca Rae, Perola Norrby, José Luis Belmonte Vázquez, Nina KannAbstract:Hydrogen borrowing provides an efficient and atom economical method for carbon–nitrogen and carbon–carbon bond formation from alcohol precursors. Glycerol is a renewable nontoxic polyol and a potential precursor to small functional organic molecules. We here report the direct amination of solketal, a 1,2-hydroxy-protected Derivative of Glycerol, via ruthenium-catalyzed hydrogen borrowing, affording up to 99% conversion and 92% isolated yield using [Ru(p-cymene)Cl2]2 as the catalyst precursor. The synthesis of an antitussive agent in 86% overall yield from solketal was also demonstrated using this methodology