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Dharmendra Saikia - One of the best experts on this subject based on the ideXlab platform.

  • antifungal activity of Glycyrrhiza glabra extracts and its active constituent glabridin
    Phytotherapy Research, 2009
    Co-Authors: Atiya Fatima, Jonnala Kotesh Kumar, Arvind S Negi, Vivek Kumar Gupta, Karuna Shanker, Suaib Luqman, Dharmendra Saikia, Mahendra P Darokar, Suchita Srivastava, Suman Preet Singh Khanuja
    Abstract:

    Glabridin, an active constituent of Glycyrrhiza glabra roots, was found to be active against both yeast and filamentous fungi. Glabridin also showed resistance modifying activity against drug resistant mutants of Candida albicans at a minimum inhibitory concentration of 31.25–250 µg/mL. Although the compound was reported earlier to be active against Candida albicans, but this is the first report of its activity against drug resistant mutants. Copyright © 2009 John Wiley & Sons, Ltd.

  • antifungal activity of Glycyrrhiza glabra extracts and its active constituent glabridin
    Phytotherapy Research, 2009
    Co-Authors: Atiya Fatima, Jonnala Kotesh Kumar, Arvind S Negi, Karuna Shanker, Suaib Luqman, Dharmendra Saikia, Mahendra P Darokar, Vivek Gupta, Suchita Srivastava, Suman Preet Singh Khanuja
    Abstract:

    Glabridin, an active constituent of Glycyrrhiza glabra roots, was found to be active against both yeast and filamentous fungi. Glabridin also showed resistance modifying activity against drug resistant mutants of Candida albicans at a minimum inhibitory concentration of 31.25-250 microg/mL. Although the compound was reported earlier to be active against Candida albicans, but this is the first report of its activity against drug resistant mutants.

  • antimicrobial potential of Glycyrrhiza glabra roots
    Journal of Ethnopharmacology, 2008
    Co-Authors: Vivek Kumar Gupta, Atiya Fatima, Uzma Faridi, Neha Rahuja, Jonnala Kotesh Kumar, Arvind S Negi, Brijesh S Sisodia, Karuna Shanker, Suaib Luqman, Dharmendra Saikia
    Abstract:

    Abstract The present study was aimed to investigate antimicrobial potential of Glycyrrhiza glabra roots. Antimycobacterial activity of Glycyrrhiza glabra was found at 500 μg/mL concentration. Bioactivity guided phytochemical analysis identified glabridin as potentially active against both Mycobacterium tuberculosis H37Ra and H37Rv strains at 29.16 μg/mL concentration. It exhibited antimicrobial activity against both Gram-positive and Gram-negative bacteria. Our results indicate potential use of licorice as antitubercular agent through systemic experiments and sophisticated anti-TB assay.

Atiya Fatima - One of the best experts on this subject based on the ideXlab platform.

  • antifungal activity of Glycyrrhiza glabra extracts and its active constituent glabridin
    Phytotherapy Research, 2009
    Co-Authors: Atiya Fatima, Jonnala Kotesh Kumar, Arvind S Negi, Vivek Kumar Gupta, Karuna Shanker, Suaib Luqman, Dharmendra Saikia, Mahendra P Darokar, Suchita Srivastava, Suman Preet Singh Khanuja
    Abstract:

    Glabridin, an active constituent of Glycyrrhiza glabra roots, was found to be active against both yeast and filamentous fungi. Glabridin also showed resistance modifying activity against drug resistant mutants of Candida albicans at a minimum inhibitory concentration of 31.25–250 µg/mL. Although the compound was reported earlier to be active against Candida albicans, but this is the first report of its activity against drug resistant mutants. Copyright © 2009 John Wiley & Sons, Ltd.

  • antifungal activity of Glycyrrhiza glabra extracts and its active constituent glabridin
    Phytotherapy Research, 2009
    Co-Authors: Atiya Fatima, Jonnala Kotesh Kumar, Arvind S Negi, Karuna Shanker, Suaib Luqman, Dharmendra Saikia, Mahendra P Darokar, Vivek Gupta, Suchita Srivastava, Suman Preet Singh Khanuja
    Abstract:

    Glabridin, an active constituent of Glycyrrhiza glabra roots, was found to be active against both yeast and filamentous fungi. Glabridin also showed resistance modifying activity against drug resistant mutants of Candida albicans at a minimum inhibitory concentration of 31.25-250 microg/mL. Although the compound was reported earlier to be active against Candida albicans, but this is the first report of its activity against drug resistant mutants.

  • antimicrobial potential of Glycyrrhiza glabra roots
    Journal of Ethnopharmacology, 2008
    Co-Authors: Vivek Kumar Gupta, Atiya Fatima, Uzma Faridi, Neha Rahuja, Jonnala Kotesh Kumar, Arvind S Negi, Brijesh S Sisodia, Karuna Shanker, Suaib Luqman, Dharmendra Saikia
    Abstract:

    Abstract The present study was aimed to investigate antimicrobial potential of Glycyrrhiza glabra roots. Antimycobacterial activity of Glycyrrhiza glabra was found at 500 μg/mL concentration. Bioactivity guided phytochemical analysis identified glabridin as potentially active against both Mycobacterium tuberculosis H37Ra and H37Rv strains at 29.16 μg/mL concentration. It exhibited antimicrobial activity against both Gram-positive and Gram-negative bacteria. Our results indicate potential use of licorice as antitubercular agent through systemic experiments and sophisticated anti-TB assay.

  • rp hplc method for the quantitation of glabridin in yashti madhu Glycyrrhiza glabra
    Chromatographia, 2007
    Co-Authors: Karuna Shanker, Atiya Fatima, Arvind S Negi, Mahendra P Darokar, Vivek Gupta, Madan M Gupta, Suman Preet Singh Khanuja
    Abstract:

    A reverse phase high performance liquid chromatographic method is developed for the quantitation of glabridin in Glycyrrhiza glabra, using C18 column with acetonitrile-water containing 2% AcOH (70:30) as an eluent. Glabridin is detected by UV absorption at 280 nm after separation by the chromatographic system. Good linearity was obtained in the working range of the concentration (0.01–0.1 mg mL−1), with correlation coefficients 0.999. Limit of detection and limit of quantitation were 0.0195 and 0.065 mg mL−1. The method was validated under ICH guidelines. The described method can be utilized for routine analysis (assays and stability tests) of G. glabra extracts and Ayurvedic medicine based on Yashti-madhu.

Suman Preet Singh Khanuja - One of the best experts on this subject based on the ideXlab platform.

  • antifungal activity of Glycyrrhiza glabra extracts and its active constituent glabridin
    Phytotherapy Research, 2009
    Co-Authors: Atiya Fatima, Jonnala Kotesh Kumar, Arvind S Negi, Karuna Shanker, Suaib Luqman, Dharmendra Saikia, Mahendra P Darokar, Vivek Gupta, Suchita Srivastava, Suman Preet Singh Khanuja
    Abstract:

    Glabridin, an active constituent of Glycyrrhiza glabra roots, was found to be active against both yeast and filamentous fungi. Glabridin also showed resistance modifying activity against drug resistant mutants of Candida albicans at a minimum inhibitory concentration of 31.25-250 microg/mL. Although the compound was reported earlier to be active against Candida albicans, but this is the first report of its activity against drug resistant mutants.

  • antifungal activity of Glycyrrhiza glabra extracts and its active constituent glabridin
    Phytotherapy Research, 2009
    Co-Authors: Atiya Fatima, Jonnala Kotesh Kumar, Arvind S Negi, Vivek Kumar Gupta, Karuna Shanker, Suaib Luqman, Dharmendra Saikia, Mahendra P Darokar, Suchita Srivastava, Suman Preet Singh Khanuja
    Abstract:

    Glabridin, an active constituent of Glycyrrhiza glabra roots, was found to be active against both yeast and filamentous fungi. Glabridin also showed resistance modifying activity against drug resistant mutants of Candida albicans at a minimum inhibitory concentration of 31.25–250 µg/mL. Although the compound was reported earlier to be active against Candida albicans, but this is the first report of its activity against drug resistant mutants. Copyright © 2009 John Wiley & Sons, Ltd.

  • rp hplc method for the quantitation of glabridin in yashti madhu Glycyrrhiza glabra
    Chromatographia, 2007
    Co-Authors: Karuna Shanker, Atiya Fatima, Arvind S Negi, Mahendra P Darokar, Vivek Gupta, Madan M Gupta, Suman Preet Singh Khanuja
    Abstract:

    A reverse phase high performance liquid chromatographic method is developed for the quantitation of glabridin in Glycyrrhiza glabra, using C18 column with acetonitrile-water containing 2% AcOH (70:30) as an eluent. Glabridin is detected by UV absorption at 280 nm after separation by the chromatographic system. Good linearity was obtained in the working range of the concentration (0.01–0.1 mg mL−1), with correlation coefficients 0.999. Limit of detection and limit of quantitation were 0.0195 and 0.065 mg mL−1. The method was validated under ICH guidelines. The described method can be utilized for routine analysis (assays and stability tests) of G. glabra extracts and Ayurvedic medicine based on Yashti-madhu.

Jonnala Kotesh Kumar - One of the best experts on this subject based on the ideXlab platform.

  • antifungal activity of Glycyrrhiza glabra extracts and its active constituent glabridin
    Phytotherapy Research, 2009
    Co-Authors: Atiya Fatima, Jonnala Kotesh Kumar, Arvind S Negi, Vivek Kumar Gupta, Karuna Shanker, Suaib Luqman, Dharmendra Saikia, Mahendra P Darokar, Suchita Srivastava, Suman Preet Singh Khanuja
    Abstract:

    Glabridin, an active constituent of Glycyrrhiza glabra roots, was found to be active against both yeast and filamentous fungi. Glabridin also showed resistance modifying activity against drug resistant mutants of Candida albicans at a minimum inhibitory concentration of 31.25–250 µg/mL. Although the compound was reported earlier to be active against Candida albicans, but this is the first report of its activity against drug resistant mutants. Copyright © 2009 John Wiley & Sons, Ltd.

  • antifungal activity of Glycyrrhiza glabra extracts and its active constituent glabridin
    Phytotherapy Research, 2009
    Co-Authors: Atiya Fatima, Jonnala Kotesh Kumar, Arvind S Negi, Karuna Shanker, Suaib Luqman, Dharmendra Saikia, Mahendra P Darokar, Vivek Gupta, Suchita Srivastava, Suman Preet Singh Khanuja
    Abstract:

    Glabridin, an active constituent of Glycyrrhiza glabra roots, was found to be active against both yeast and filamentous fungi. Glabridin also showed resistance modifying activity against drug resistant mutants of Candida albicans at a minimum inhibitory concentration of 31.25-250 microg/mL. Although the compound was reported earlier to be active against Candida albicans, but this is the first report of its activity against drug resistant mutants.

  • antimicrobial potential of Glycyrrhiza glabra roots
    Journal of Ethnopharmacology, 2008
    Co-Authors: Vivek Kumar Gupta, Atiya Fatima, Uzma Faridi, Neha Rahuja, Jonnala Kotesh Kumar, Arvind S Negi, Brijesh S Sisodia, Karuna Shanker, Suaib Luqman, Dharmendra Saikia
    Abstract:

    Abstract The present study was aimed to investigate antimicrobial potential of Glycyrrhiza glabra roots. Antimycobacterial activity of Glycyrrhiza glabra was found at 500 μg/mL concentration. Bioactivity guided phytochemical analysis identified glabridin as potentially active against both Mycobacterium tuberculosis H37Ra and H37Rv strains at 29.16 μg/mL concentration. It exhibited antimicrobial activity against both Gram-positive and Gram-negative bacteria. Our results indicate potential use of licorice as antitubercular agent through systemic experiments and sophisticated anti-TB assay.

Suaib Luqman - One of the best experts on this subject based on the ideXlab platform.

  • antifungal activity of Glycyrrhiza glabra extracts and its active constituent glabridin
    Phytotherapy Research, 2009
    Co-Authors: Atiya Fatima, Jonnala Kotesh Kumar, Arvind S Negi, Vivek Kumar Gupta, Karuna Shanker, Suaib Luqman, Dharmendra Saikia, Mahendra P Darokar, Suchita Srivastava, Suman Preet Singh Khanuja
    Abstract:

    Glabridin, an active constituent of Glycyrrhiza glabra roots, was found to be active against both yeast and filamentous fungi. Glabridin also showed resistance modifying activity against drug resistant mutants of Candida albicans at a minimum inhibitory concentration of 31.25–250 µg/mL. Although the compound was reported earlier to be active against Candida albicans, but this is the first report of its activity against drug resistant mutants. Copyright © 2009 John Wiley & Sons, Ltd.

  • antifungal activity of Glycyrrhiza glabra extracts and its active constituent glabridin
    Phytotherapy Research, 2009
    Co-Authors: Atiya Fatima, Jonnala Kotesh Kumar, Arvind S Negi, Karuna Shanker, Suaib Luqman, Dharmendra Saikia, Mahendra P Darokar, Vivek Gupta, Suchita Srivastava, Suman Preet Singh Khanuja
    Abstract:

    Glabridin, an active constituent of Glycyrrhiza glabra roots, was found to be active against both yeast and filamentous fungi. Glabridin also showed resistance modifying activity against drug resistant mutants of Candida albicans at a minimum inhibitory concentration of 31.25-250 microg/mL. Although the compound was reported earlier to be active against Candida albicans, but this is the first report of its activity against drug resistant mutants.

  • antimicrobial potential of Glycyrrhiza glabra roots
    Journal of Ethnopharmacology, 2008
    Co-Authors: Vivek Kumar Gupta, Atiya Fatima, Uzma Faridi, Neha Rahuja, Jonnala Kotesh Kumar, Arvind S Negi, Brijesh S Sisodia, Karuna Shanker, Suaib Luqman, Dharmendra Saikia
    Abstract:

    Abstract The present study was aimed to investigate antimicrobial potential of Glycyrrhiza glabra roots. Antimycobacterial activity of Glycyrrhiza glabra was found at 500 μg/mL concentration. Bioactivity guided phytochemical analysis identified glabridin as potentially active against both Mycobacterium tuberculosis H37Ra and H37Rv strains at 29.16 μg/mL concentration. It exhibited antimicrobial activity against both Gram-positive and Gram-negative bacteria. Our results indicate potential use of licorice as antitubercular agent through systemic experiments and sophisticated anti-TB assay.