The Experts below are selected from a list of 32292 Experts worldwide ranked by ideXlab platform

Åke Svensson - One of the best experts on this subject based on the ideXlab platform.

  • Rheumatoid arthritis, Gold Therapy, contact allergy and blood cytokines
    BMC Dermatology, 2002
    Co-Authors: Åke Svensson, Magnus Bruze, Halvor Möller, Bert Björkner, Ido Leden, Jan Theander, Kjell Ohlsson, Carina Linder
    Abstract:

    Objective To study the clinical and biochemical effects of a low starting dose for Gold Therapy in rheumatoid arthritis patients with a contact allergy to Gold. Methods Serum cytokines were assayed before and 24 h after the first injection of Gold sodium thiomalate (GSTM). Results Contact allergy to Gold was found in 4 of 19 patients. Compared to Gold-negative patients (starting dose: 10 mg GSTM), there was a larger increase in serum TNFalpha (p < 0.05), sTNF-R1 (NS), and IL-1 ra (p < 0.05) in Gold-allergic patients. Conclusions Cytokines are released in blood by GSTM in RA patients with Gold allergy. To minimize the risk of acute adverse reactions the starting dose of GSTM should be lowered to 5 mg. Alternatively, patients should be patch-tested before Gold Therapy; in test-positive cases, 5 mg is recommended as the first dose.

  • Rheumatoid arthritis, Gold Therapy, contact allergy and blood cytokines
    BMC dermatology, 2002
    Co-Authors: Åke Svensson, Magnus Bruze, Halvor Möller, Bert Björkner, Ido Leden, Jan Theander, Kjell Ohlsson, Carina Linder
    Abstract:

    Objective To study the clinical and biochemical effects of a low starting dose for Gold Therapy in rheumatoid arthritis patients with a contact allergy to Gold.

  • Contact allergy to Gold and Gold Therapy in patients with rheumatoid arthritis.
    Acta dermato-venereologica, 1997
    Co-Authors: Halvor Möller, Magnus Bruze, Åke Svensson, Bert Björkner, Lindroth Y, Manthorpe R, Theander J
    Abstract:

    Patients with rheumatoid arthritis were investigated for contact allergy to Gold in connection with treatment with Gold preparations. There were 57 patients with rheumatoid arthritis previously treated with Gold, with or without cutaneous side-effects, as well as 20 patients intended for such treatment; all were exposed to patch and intradermal tests with Gold sodium thiosulfate, Gold sodium thiomalate and auranofin. Contact allergy to Gold was demonstrated in 8 out of 77 patients (10.4%). In the retrospective material, Gold allergy was found in 1.8%, in the prospective material in 35.0%. Contact allergy to Gold is very frequent among patients with rheumatoid arthritis before Gold Therapy. In order to avoid early hypersensitivity reactions skin tests should be carried out before Gold Therapy is instituted.

Carina Linder - One of the best experts on this subject based on the ideXlab platform.

  • Rheumatoid arthritis, Gold Therapy, contact allergy and blood cytokines
    BMC dermatology, 2002
    Co-Authors: Åke Svensson, Magnus Bruze, Halvor Möller, Bert Björkner, Ido Leden, Jan Theander, Kjell Ohlsson, Carina Linder
    Abstract:

    Objective To study the clinical and biochemical effects of a low starting dose for Gold Therapy in rheumatoid arthritis patients with a contact allergy to Gold.

  • Rheumatoid arthritis, Gold Therapy, contact allergy and blood cytokines
    BMC Dermatology, 2002
    Co-Authors: Åke Svensson, Magnus Bruze, Halvor Möller, Bert Björkner, Ido Leden, Jan Theander, Kjell Ohlsson, Carina Linder
    Abstract:

    Objective To study the clinical and biochemical effects of a low starting dose for Gold Therapy in rheumatoid arthritis patients with a contact allergy to Gold. Methods Serum cytokines were assayed before and 24 h after the first injection of Gold sodium thiomalate (GSTM). Results Contact allergy to Gold was found in 4 of 19 patients. Compared to Gold-negative patients (starting dose: 10 mg GSTM), there was a larger increase in serum TNFalpha (p < 0.05), sTNF-R1 (NS), and IL-1 ra (p < 0.05) in Gold-allergic patients. Conclusions Cytokines are released in blood by GSTM in RA patients with Gold allergy. To minimize the risk of acute adverse reactions the starting dose of GSTM should be lowered to 5 mg. Alternatively, patients should be patch-tested before Gold Therapy; in test-positive cases, 5 mg is recommended as the first dose.

Halvor Möller - One of the best experts on this subject based on the ideXlab platform.

  • Rheumatoid arthritis, Gold Therapy, contact allergy and blood cytokines
    BMC Dermatology, 2002
    Co-Authors: Åke Svensson, Magnus Bruze, Halvor Möller, Bert Björkner, Ido Leden, Jan Theander, Kjell Ohlsson, Carina Linder
    Abstract:

    Objective To study the clinical and biochemical effects of a low starting dose for Gold Therapy in rheumatoid arthritis patients with a contact allergy to Gold. Methods Serum cytokines were assayed before and 24 h after the first injection of Gold sodium thiomalate (GSTM). Results Contact allergy to Gold was found in 4 of 19 patients. Compared to Gold-negative patients (starting dose: 10 mg GSTM), there was a larger increase in serum TNFalpha (p < 0.05), sTNF-R1 (NS), and IL-1 ra (p < 0.05) in Gold-allergic patients. Conclusions Cytokines are released in blood by GSTM in RA patients with Gold allergy. To minimize the risk of acute adverse reactions the starting dose of GSTM should be lowered to 5 mg. Alternatively, patients should be patch-tested before Gold Therapy; in test-positive cases, 5 mg is recommended as the first dose.

  • Rheumatoid arthritis, Gold Therapy, contact allergy and blood cytokines
    BMC dermatology, 2002
    Co-Authors: Åke Svensson, Magnus Bruze, Halvor Möller, Bert Björkner, Ido Leden, Jan Theander, Kjell Ohlsson, Carina Linder
    Abstract:

    Objective To study the clinical and biochemical effects of a low starting dose for Gold Therapy in rheumatoid arthritis patients with a contact allergy to Gold.

  • Contact allergy to Gold and Gold Therapy in patients with rheumatoid arthritis.
    Acta dermato-venereologica, 1997
    Co-Authors: Halvor Möller, Magnus Bruze, Åke Svensson, Bert Björkner, Lindroth Y, Manthorpe R, Theander J
    Abstract:

    Patients with rheumatoid arthritis were investigated for contact allergy to Gold in connection with treatment with Gold preparations. There were 57 patients with rheumatoid arthritis previously treated with Gold, with or without cutaneous side-effects, as well as 20 patients intended for such treatment; all were exposed to patch and intradermal tests with Gold sodium thiosulfate, Gold sodium thiomalate and auranofin. Contact allergy to Gold was demonstrated in 8 out of 77 patients (10.4%). In the retrospective material, Gold allergy was found in 1.8%, in the prospective material in 35.0%. Contact allergy to Gold is very frequent among patients with rheumatoid arthritis before Gold Therapy. In order to avoid early hypersensitivity reactions skin tests should be carried out before Gold Therapy is instituted.

Bert Björkner - One of the best experts on this subject based on the ideXlab platform.

  • Rheumatoid arthritis, Gold Therapy, contact allergy and blood cytokines
    BMC Dermatology, 2002
    Co-Authors: Åke Svensson, Magnus Bruze, Halvor Möller, Bert Björkner, Ido Leden, Jan Theander, Kjell Ohlsson, Carina Linder
    Abstract:

    Objective To study the clinical and biochemical effects of a low starting dose for Gold Therapy in rheumatoid arthritis patients with a contact allergy to Gold. Methods Serum cytokines were assayed before and 24 h after the first injection of Gold sodium thiomalate (GSTM). Results Contact allergy to Gold was found in 4 of 19 patients. Compared to Gold-negative patients (starting dose: 10 mg GSTM), there was a larger increase in serum TNFalpha (p < 0.05), sTNF-R1 (NS), and IL-1 ra (p < 0.05) in Gold-allergic patients. Conclusions Cytokines are released in blood by GSTM in RA patients with Gold allergy. To minimize the risk of acute adverse reactions the starting dose of GSTM should be lowered to 5 mg. Alternatively, patients should be patch-tested before Gold Therapy; in test-positive cases, 5 mg is recommended as the first dose.

  • Rheumatoid arthritis, Gold Therapy, contact allergy and blood cytokines
    BMC dermatology, 2002
    Co-Authors: Åke Svensson, Magnus Bruze, Halvor Möller, Bert Björkner, Ido Leden, Jan Theander, Kjell Ohlsson, Carina Linder
    Abstract:

    Objective To study the clinical and biochemical effects of a low starting dose for Gold Therapy in rheumatoid arthritis patients with a contact allergy to Gold.

  • Contact allergy to Gold and Gold Therapy in patients with rheumatoid arthritis.
    Acta dermato-venereologica, 1997
    Co-Authors: Halvor Möller, Magnus Bruze, Åke Svensson, Bert Björkner, Lindroth Y, Manthorpe R, Theander J
    Abstract:

    Patients with rheumatoid arthritis were investigated for contact allergy to Gold in connection with treatment with Gold preparations. There were 57 patients with rheumatoid arthritis previously treated with Gold, with or without cutaneous side-effects, as well as 20 patients intended for such treatment; all were exposed to patch and intradermal tests with Gold sodium thiosulfate, Gold sodium thiomalate and auranofin. Contact allergy to Gold was demonstrated in 8 out of 77 patients (10.4%). In the retrospective material, Gold allergy was found in 1.8%, in the prospective material in 35.0%. Contact allergy to Gold is very frequent among patients with rheumatoid arthritis before Gold Therapy. In order to avoid early hypersensitivity reactions skin tests should be carried out before Gold Therapy is instituted.

Magnus Bruze - One of the best experts on this subject based on the ideXlab platform.

  • Rheumatoid arthritis, Gold Therapy, contact allergy and blood cytokines
    BMC Dermatology, 2002
    Co-Authors: Åke Svensson, Magnus Bruze, Halvor Möller, Bert Björkner, Ido Leden, Jan Theander, Kjell Ohlsson, Carina Linder
    Abstract:

    Objective To study the clinical and biochemical effects of a low starting dose for Gold Therapy in rheumatoid arthritis patients with a contact allergy to Gold. Methods Serum cytokines were assayed before and 24 h after the first injection of Gold sodium thiomalate (GSTM). Results Contact allergy to Gold was found in 4 of 19 patients. Compared to Gold-negative patients (starting dose: 10 mg GSTM), there was a larger increase in serum TNFalpha (p < 0.05), sTNF-R1 (NS), and IL-1 ra (p < 0.05) in Gold-allergic patients. Conclusions Cytokines are released in blood by GSTM in RA patients with Gold allergy. To minimize the risk of acute adverse reactions the starting dose of GSTM should be lowered to 5 mg. Alternatively, patients should be patch-tested before Gold Therapy; in test-positive cases, 5 mg is recommended as the first dose.

  • Rheumatoid arthritis, Gold Therapy, contact allergy and blood cytokines
    BMC dermatology, 2002
    Co-Authors: Åke Svensson, Magnus Bruze, Halvor Möller, Bert Björkner, Ido Leden, Jan Theander, Kjell Ohlsson, Carina Linder
    Abstract:

    Objective To study the clinical and biochemical effects of a low starting dose for Gold Therapy in rheumatoid arthritis patients with a contact allergy to Gold.

  • Contact allergy to Gold and Gold Therapy in patients with rheumatoid arthritis.
    Acta dermato-venereologica, 1997
    Co-Authors: Halvor Möller, Magnus Bruze, Åke Svensson, Bert Björkner, Lindroth Y, Manthorpe R, Theander J
    Abstract:

    Patients with rheumatoid arthritis were investigated for contact allergy to Gold in connection with treatment with Gold preparations. There were 57 patients with rheumatoid arthritis previously treated with Gold, with or without cutaneous side-effects, as well as 20 patients intended for such treatment; all were exposed to patch and intradermal tests with Gold sodium thiosulfate, Gold sodium thiomalate and auranofin. Contact allergy to Gold was demonstrated in 8 out of 77 patients (10.4%). In the retrospective material, Gold allergy was found in 1.8%, in the prospective material in 35.0%. Contact allergy to Gold is very frequent among patients with rheumatoid arthritis before Gold Therapy. In order to avoid early hypersensitivity reactions skin tests should be carried out before Gold Therapy is instituted.