The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Natalija Novak - One of the best experts on this subject based on the ideXlab platform.
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New treatment modalities for Granuloma Faciale
British Journal of Dermatology, 2003Co-Authors: E. Ludwig, J.-p. Allam, T. Bieber, Natalija NovakAbstract:: Granuloma Faciale (GF) is a rare, chronic skin disorder in which numerous treatment modalities have been used without any consistent long-term effect. We report three cases of GF, two of which were successfully treated with the Laserscope potassium-titanyl-phosphate 532-nm laser within 2 weeks and one with topical tacrolimus ointment 0.1%. Our observations suggest that these new treatment modalities for GF, which we report here for the first time, can provide effective and non-invasive treatment for this disease.
Peter Elsner - One of the best experts on this subject based on the ideXlab platform.
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Granuloma Faciale treatment a systematic review
Acta Dermato-venereologica, 2018Co-Authors: Claudia Lindhaus, Peter ElsnerAbstract:Granuloma Faciale is an uncommon benign chronic dermatosis characterized by reddish-brown to violaceous asymptomatic plaques appearing predominantly on the face. The pathogenesis of Granuloma Faciale remains unclear, and it is frequently unresponsive to therapy. This systematic review aims to summarize all recent publications on the management of Granuloma Faciale. The publications are mainly individual case reports, small case series and a few retrospective studies. Treatment options included topical, intralesional and systemic corticosteroids, topical pimecrolimus and tacrolimus, topical and systemic dapsone, systemic hydroxychloroquine, clofazimine, and tumour necrosis factor-alpha inhibitors. More invasive therapies using lasers as well as cryosurgery and surgery were also reported. Topical glucocorticosteroids and tacrolimus remain treatments of first choice, possibly supplemented by topical dapsone.
Moise L Levy - One of the best experts on this subject based on the ideXlab platform.
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Granuloma Faciale in a child successfully treated with the pulsed dye laser
Journal of The American Academy of Dermatology, 1999Co-Authors: Jenifer Hall Welsh, Theresa L Schroeder, Moise L LevyAbstract:Abstract Granuloma Faciale, a rare, chronic, cutaneous disorder, is uncommon in children. Numerous treatment modalities have been used to treat Granuloma Faciale but none are consistently effective. In addition, many of the previously used therapies have unwanted side effects or are not well tolerated by children. We report a case of Granuloma Faciale in an 11-year-old child successfully treated with the pulsed dye laser. To our knowledge, this is the first report of this treatment modality for Granuloma Faciale. (J Am Acad Dermatol 1999;41:351-3.)
E. Ludwig - One of the best experts on this subject based on the ideXlab platform.
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New treatment modalities for Granuloma Faciale
British Journal of Dermatology, 2003Co-Authors: E. Ludwig, J.-p. Allam, T. Bieber, Natalija NovakAbstract:: Granuloma Faciale (GF) is a rare, chronic skin disorder in which numerous treatment modalities have been used without any consistent long-term effect. We report three cases of GF, two of which were successfully treated with the Laserscope potassium-titanyl-phosphate 532-nm laser within 2 weeks and one with topical tacrolimus ointment 0.1%. Our observations suggest that these new treatment modalities for GF, which we report here for the first time, can provide effective and non-invasive treatment for this disease.
Philip E Leboit - One of the best experts on this subject based on the ideXlab platform.
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localized chronic fibrosing vasculitis of the skin an inflammatory reaction that occurs in settings other than erythema elevatum diutinum and Granuloma Faciale
The American Journal of Surgical Pathology, 1997Co-Authors: J A Carlson, Philip E LeboitAbstract:Erythema elevatum diutinum (EED) and Granuloma Faciale (GF) are chronic, localized forms of cutaneous leukocytoclastic vasculitis that result in patterned (storiform or concentric) fibrosis. EED often occurs in systemically ill patients as bilaterally symmetrical plaques, papules, or nodules, often over the dorsa of joints. GF occurs as one or a few plaques on the face. Eosinophils and plasma cells are prominent in GF, whereas neutrophils are plentiful in EED. Rarely, extrafacial lesions accompany facial ones in GF, and there are a few reports of upper respiratory tract masses with GF-like histologic features. We report on eight patients with solitary cutaneous lesions with histologic features similar to those of EED or GF, but whose clinical picture was not that of either disease. One, whose histology resembled GF, had a large multinodular dermal and subcutaneous mass that persisted despite attempted resection. Unusual histologic findings in other cases included storiform fibrosis with dense infiltrates of plasma cells, branching nerve fascicles admixed with EED-like changes, and EED-like areas adjacent to zones mimicking a sclerotic fibroma. Chronic fibrosing venulitis can be seen outside the stereotypic settings of GF and EED and is an inflammatory reaction pattern that does not signify a specific diagnosis. Because of transitions between EED or GF-like areas and those of patterned sclerosis with plasma cell-rich infiltrates, we believe that some "inflammatory pseudotumors" of the skin, and perhaps of other sites could be the result of localized vasculitis.
