The Experts below are selected from a list of 126 Experts worldwide ranked by ideXlab platform
Nico Bruining - One of the best experts on this subject based on the ideXlab platform.
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evaluation of four year coronary artery response after sirolimus eluting stent implantation using serial quantitative intravascular ultrasound and computer assisted Grayscale Value analysis for plaque composition in event free patients
Journal of the American College of Cardiology, 2005Co-Authors: Jiro Aoki, Alexandre Abizaid, Patrick W Serruys, Andrew T L Ong, Eric Boersma, Eduardo J Sousa, Nico BruiningAbstract:Objectives This study sought to evaluate the long-term arterial response after sirolimus-eluting stent implantation. Background Sirolimus-eluting stents are effective in inhibiting neointimal hyperplasia without affecting plaque volume behind the stent struts at six months. Methods Serial quantitative intravascular ultrasound and computer-assisted Grayscale Value analysis over four years were performed in 23 event-free patients treated with sirolimus-eluting stents. Results In the first two years, the mean plaque volume (155.5 ± 42.8 mm3post-procedure and 156.8 ± 57.7 mm3at two years, p = 0.86) and plaque compositional change expressed as mean percent hypoechogenic tissue of the plaque behind the stent struts (78.9 ± 8.6% post-procedure and 78.2 ± 8.9% at two years, p = 0.67) did not significantly change. However, significant plaque shrinking (change in plaque volume = −18.4 mm3, p = 0.02) with an increase in plaque echogenicity (change in percent hypoechogenic tissue = −7.8%, p Conclusions Between two and four years after sirolimus-eluting stent implantation, peri-stent tissue shrank with a concomitant increase in echogenicity. These intravascular ultrasound findings suggest that late chronic artery responses may evolve for up to four years after sirolimus-eluting stent implantation. In addition, the fact that the neointima does not significantly change from two to four years may suggest that the biological phenomenon of a delayed healing response has begun to subside.
Jiro Aoki - One of the best experts on this subject based on the ideXlab platform.
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evaluation of four year coronary artery response after sirolimus eluting stent implantation using serial quantitative intravascular ultrasound and computer assisted Grayscale Value analysis for plaque composition in event free patients
Journal of the American College of Cardiology, 2005Co-Authors: Jiro Aoki, Alexandre Abizaid, Patrick W Serruys, Andrew T L Ong, Eric Boersma, Eduardo J Sousa, Nico BruiningAbstract:Objectives This study sought to evaluate the long-term arterial response after sirolimus-eluting stent implantation. Background Sirolimus-eluting stents are effective in inhibiting neointimal hyperplasia without affecting plaque volume behind the stent struts at six months. Methods Serial quantitative intravascular ultrasound and computer-assisted Grayscale Value analysis over four years were performed in 23 event-free patients treated with sirolimus-eluting stents. Results In the first two years, the mean plaque volume (155.5 ± 42.8 mm3post-procedure and 156.8 ± 57.7 mm3at two years, p = 0.86) and plaque compositional change expressed as mean percent hypoechogenic tissue of the plaque behind the stent struts (78.9 ± 8.6% post-procedure and 78.2 ± 8.9% at two years, p = 0.67) did not significantly change. However, significant plaque shrinking (change in plaque volume = −18.4 mm3, p = 0.02) with an increase in plaque echogenicity (change in percent hypoechogenic tissue = −7.8%, p Conclusions Between two and four years after sirolimus-eluting stent implantation, peri-stent tissue shrank with a concomitant increase in echogenicity. These intravascular ultrasound findings suggest that late chronic artery responses may evolve for up to four years after sirolimus-eluting stent implantation. In addition, the fact that the neointima does not significantly change from two to four years may suggest that the biological phenomenon of a delayed healing response has begun to subside.
Eduardo J Sousa - One of the best experts on this subject based on the ideXlab platform.
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evaluation of four year coronary artery response after sirolimus eluting stent implantation using serial quantitative intravascular ultrasound and computer assisted Grayscale Value analysis for plaque composition in event free patients
Journal of the American College of Cardiology, 2005Co-Authors: Jiro Aoki, Alexandre Abizaid, Patrick W Serruys, Andrew T L Ong, Eric Boersma, Eduardo J Sousa, Nico BruiningAbstract:Objectives This study sought to evaluate the long-term arterial response after sirolimus-eluting stent implantation. Background Sirolimus-eluting stents are effective in inhibiting neointimal hyperplasia without affecting plaque volume behind the stent struts at six months. Methods Serial quantitative intravascular ultrasound and computer-assisted Grayscale Value analysis over four years were performed in 23 event-free patients treated with sirolimus-eluting stents. Results In the first two years, the mean plaque volume (155.5 ± 42.8 mm3post-procedure and 156.8 ± 57.7 mm3at two years, p = 0.86) and plaque compositional change expressed as mean percent hypoechogenic tissue of the plaque behind the stent struts (78.9 ± 8.6% post-procedure and 78.2 ± 8.9% at two years, p = 0.67) did not significantly change. However, significant plaque shrinking (change in plaque volume = −18.4 mm3, p = 0.02) with an increase in plaque echogenicity (change in percent hypoechogenic tissue = −7.8%, p Conclusions Between two and four years after sirolimus-eluting stent implantation, peri-stent tissue shrank with a concomitant increase in echogenicity. These intravascular ultrasound findings suggest that late chronic artery responses may evolve for up to four years after sirolimus-eluting stent implantation. In addition, the fact that the neointima does not significantly change from two to four years may suggest that the biological phenomenon of a delayed healing response has begun to subside.
Patrick W Serruys - One of the best experts on this subject based on the ideXlab platform.
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evaluation of four year coronary artery response after sirolimus eluting stent implantation using serial quantitative intravascular ultrasound and computer assisted Grayscale Value analysis for plaque composition in event free patients
Journal of the American College of Cardiology, 2005Co-Authors: Jiro Aoki, Alexandre Abizaid, Patrick W Serruys, Andrew T L Ong, Eric Boersma, Eduardo J Sousa, Nico BruiningAbstract:Objectives This study sought to evaluate the long-term arterial response after sirolimus-eluting stent implantation. Background Sirolimus-eluting stents are effective in inhibiting neointimal hyperplasia without affecting plaque volume behind the stent struts at six months. Methods Serial quantitative intravascular ultrasound and computer-assisted Grayscale Value analysis over four years were performed in 23 event-free patients treated with sirolimus-eluting stents. Results In the first two years, the mean plaque volume (155.5 ± 42.8 mm3post-procedure and 156.8 ± 57.7 mm3at two years, p = 0.86) and plaque compositional change expressed as mean percent hypoechogenic tissue of the plaque behind the stent struts (78.9 ± 8.6% post-procedure and 78.2 ± 8.9% at two years, p = 0.67) did not significantly change. However, significant plaque shrinking (change in plaque volume = −18.4 mm3, p = 0.02) with an increase in plaque echogenicity (change in percent hypoechogenic tissue = −7.8%, p Conclusions Between two and four years after sirolimus-eluting stent implantation, peri-stent tissue shrank with a concomitant increase in echogenicity. These intravascular ultrasound findings suggest that late chronic artery responses may evolve for up to four years after sirolimus-eluting stent implantation. In addition, the fact that the neointima does not significantly change from two to four years may suggest that the biological phenomenon of a delayed healing response has begun to subside.
Andrew T L Ong - One of the best experts on this subject based on the ideXlab platform.
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evaluation of four year coronary artery response after sirolimus eluting stent implantation using serial quantitative intravascular ultrasound and computer assisted Grayscale Value analysis for plaque composition in event free patients
Journal of the American College of Cardiology, 2005Co-Authors: Jiro Aoki, Alexandre Abizaid, Patrick W Serruys, Andrew T L Ong, Eric Boersma, Eduardo J Sousa, Nico BruiningAbstract:Objectives This study sought to evaluate the long-term arterial response after sirolimus-eluting stent implantation. Background Sirolimus-eluting stents are effective in inhibiting neointimal hyperplasia without affecting plaque volume behind the stent struts at six months. Methods Serial quantitative intravascular ultrasound and computer-assisted Grayscale Value analysis over four years were performed in 23 event-free patients treated with sirolimus-eluting stents. Results In the first two years, the mean plaque volume (155.5 ± 42.8 mm3post-procedure and 156.8 ± 57.7 mm3at two years, p = 0.86) and plaque compositional change expressed as mean percent hypoechogenic tissue of the plaque behind the stent struts (78.9 ± 8.6% post-procedure and 78.2 ± 8.9% at two years, p = 0.67) did not significantly change. However, significant plaque shrinking (change in plaque volume = −18.4 mm3, p = 0.02) with an increase in plaque echogenicity (change in percent hypoechogenic tissue = −7.8%, p Conclusions Between two and four years after sirolimus-eluting stent implantation, peri-stent tissue shrank with a concomitant increase in echogenicity. These intravascular ultrasound findings suggest that late chronic artery responses may evolve for up to four years after sirolimus-eluting stent implantation. In addition, the fact that the neointima does not significantly change from two to four years may suggest that the biological phenomenon of a delayed healing response has begun to subside.
