The Experts below are selected from a list of 270 Experts worldwide ranked by ideXlab platform
Pierre Jacobs - One of the best experts on this subject based on the ideXlab platform.
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Silica‐Immobilized Second Generation Hoveyda—Grubbs: A Convenient, Recyclable and Storageable Heterogeneous Solid Catalyst.
ChemInform, 2009Co-Authors: Boris Van Berlo, Kristof Houthoofd, Bert Sels, Pierre JacobsAbstract:The second generation Hoveyda-Grubbs Metathesis catalyst was successfully immobilized on silica in pellet and powder form following a practical and fast synthesis procedure. The activity of the solid system is truly heterogeneous, efficient in various Metathesis reaction types and stable for at least 4000 TON. Ru contamination of the products was very low (ppb levels). The successful use of the robust system has been demonstrated in a continuous reactor set-up.
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silica immobilized second generation hoveyda Grubbs a convenient recyclable and storageable heterogeneous solid catalyst
Advanced Synthesis & Catalysis, 2008Co-Authors: Boris Van Berlo, Kristof Houthoofd, Bert Sels, Pierre JacobsAbstract:The second generation Hoveyda-Grubbs Metathesis catalyst was successfully immobilized on silica in pellet and powder form following a practical and fast synthesis procedure. The activity of the solid system is truly heterogeneous, efficient in various Metathesis reaction types and stable for at least 4000 TON. Ru contamination of the products was very low (ppb levels). The successful use of the robust system has been demonstrated in a continuous reactor set-up.
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Silica Immobilized Second Generation Hoveyda‐Grubbs: A Convenient, Recyclable and Storageable Heterogeneous Solid Catalyst
Advanced Synthesis & Catalysis, 2008Co-Authors: Boris Van Berlo, Kristof Houthoofd, Bert Sels, Pierre JacobsAbstract:The second generation Hoveyda-Grubbs Metathesis catalyst was successfully immobilized on silica in pellet and powder form following a practical and fast synthesis procedure. The activity of the solid system is truly heterogeneous, efficient in various Metathesis reaction types and stable for at least 4000 TON. Ru contamination of the products was very low (ppb levels). The successful use of the robust system has been demonstrated in a continuous reactor set-up.
Peter Quayle - One of the best experts on this subject based on the ideXlab platform.
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Catalyst Economy. Part 2. Sequential Metathesis—Kharasch Sequences Using the Grubbs′ Metathesis Catalysts.
ChemInform, 2006Co-Authors: Christopher David Edlin, James Faulkner, Peter QuayleAbstract:Abstract Sequential ring-closing Metathesis (RCM)–Kharasch cyclizations are promoted by the Grubbs Metathesis catalysts and provide rapid access to bicyclic lactones and lactams.
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catalyst economy part 2 sequential Metathesis kharasch sequences using the Grubbs Metathesis catalysts
Tetrahedron Letters, 2006Co-Authors: Christopher David Edlin, James Faulkner, Peter QuayleAbstract:Abstract Sequential ring-closing Metathesis (RCM)–Kharasch cyclizations are promoted by the Grubbs Metathesis catalysts and provide rapid access to bicyclic lactones and lactams.
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Intramolecular Metathesis versus Kharasch reactions using the Grubbs Metathesis catalyst: towards catalyst economy
Tetrahedron Letters, 2005Co-Authors: James Faulkner, Chris D. Edlin, David Fengas, Ian Preece, Peter Quayle, Stuart N. RichardsAbstract:The first generation Grubbs catalyst can promote either ring closing Metathesis (RCM) or atom transfer radical cyclisation reactions (ATRC) depending upon the reaction conditions employed.
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A comment on the Gurjar mechanism for alkene isomerization using the Grubbs olefin Metathesis catalysts
Synlett, 2005Co-Authors: Christopher David Edlin, James Faulkner, David Fengas, Ian Preece, Peter Quayle, Christopher K. Knight, Jeremy S. Parker, Stuart N. RichardsAbstract:The mechanism of allylic alc. isomerization in the presence of the Grubbs Metathesis catalysts is discussed. [on SciFinder (R)]
Boris Van Berlo - One of the best experts on this subject based on the ideXlab platform.
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Silica‐Immobilized Second Generation Hoveyda—Grubbs: A Convenient, Recyclable and Storageable Heterogeneous Solid Catalyst.
ChemInform, 2009Co-Authors: Boris Van Berlo, Kristof Houthoofd, Bert Sels, Pierre JacobsAbstract:The second generation Hoveyda-Grubbs Metathesis catalyst was successfully immobilized on silica in pellet and powder form following a practical and fast synthesis procedure. The activity of the solid system is truly heterogeneous, efficient in various Metathesis reaction types and stable for at least 4000 TON. Ru contamination of the products was very low (ppb levels). The successful use of the robust system has been demonstrated in a continuous reactor set-up.
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silica immobilized second generation hoveyda Grubbs a convenient recyclable and storageable heterogeneous solid catalyst
Advanced Synthesis & Catalysis, 2008Co-Authors: Boris Van Berlo, Kristof Houthoofd, Bert Sels, Pierre JacobsAbstract:The second generation Hoveyda-Grubbs Metathesis catalyst was successfully immobilized on silica in pellet and powder form following a practical and fast synthesis procedure. The activity of the solid system is truly heterogeneous, efficient in various Metathesis reaction types and stable for at least 4000 TON. Ru contamination of the products was very low (ppb levels). The successful use of the robust system has been demonstrated in a continuous reactor set-up.
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Silica Immobilized Second Generation Hoveyda‐Grubbs: A Convenient, Recyclable and Storageable Heterogeneous Solid Catalyst
Advanced Synthesis & Catalysis, 2008Co-Authors: Boris Van Berlo, Kristof Houthoofd, Bert Sels, Pierre JacobsAbstract:The second generation Hoveyda-Grubbs Metathesis catalyst was successfully immobilized on silica in pellet and powder form following a practical and fast synthesis procedure. The activity of the solid system is truly heterogeneous, efficient in various Metathesis reaction types and stable for at least 4000 TON. Ru contamination of the products was very low (ppb levels). The successful use of the robust system has been demonstrated in a continuous reactor set-up.
Bodo Dobner - One of the best experts on this subject based on the ideXlab platform.
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Structure–property relationships in a series of diglycerol tetraether model lipids and their lyotropic assemblies: the effect of branching topology and chirality
Organic & biomolecular chemistry, 2014Co-Authors: Thomas Markowski, Simon Drescher, Annette Meister, Alfred Blume, Bodo DobnerAbstract:Three novel diglycerol tetraether lipids with one membrane-spanning chain have been synthesized. These lipids contain only two or four racemic methyl branches at selected positions of the hydrophobic chains in contrast to natural lipids from archaebacterial membranes with an isoprenoid substitution pattern. The insertion of the methyl moieties was realized starting from either (RS)-citronellyl bromide or the inexpensive methyl malonic acid ethyl ester. For chain elongation the Cu-catalysed Grignard coupling reaction was used. The preparation of diglycerol tetraethers was either performed by condensing suitable blocked monoglycerol diethers by Grubbs Metathesis or by reaction of the transmembrane C32-chain with blocked glycerols followed by further alkylation steps. Finally, we could show that the resulting lipids can form closed lipid vesicles comparable to the optically pure counterparts. Therefore, these much simpler lipids compared to the natural lipids from archaebacterial membranes are also suitable for preparation of stable tailored liposomes.
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Synthesis of Optically Pure Diglycerol Tetraether Model Lipids with Non‐Natural Branching Pattern
European Journal of Organic Chemistry, 2011Co-Authors: Thomas Markowski, Simon Drescher, Annette Meister, Gerd Hause, Alfred Blume, Bodo DobnerAbstract:Three new, chain-modified, optically pure diglycerol tetraether lipids with one membrane-spanning chain have been synthesised. These lipids contain a different number and constitution of the methyl branches connected to the hydrophobic chains as compared with natural archaeal or other previously synthesised lipids. The correct chirality of the branched alkyl chain was introduced starting from commercially available (S)-citronellyl bromide. For chain elongation the Cu-catalysed Grignard coupling reaction was used. Suitable blocked glycerol ethers were condensed to the tetraether moieties by Grubbs Metathesis. The insertion of two or four optically pure methyl branches at the 10- and/or 23-positions of the alkyl chains are sufficient to mimic the main properties of natural tetraether lipids. In this context, it has been shown that these lipids can form closed lipid vesicles.
James Faulkner - One of the best experts on this subject based on the ideXlab platform.
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Catalyst Economy. Part 2. Sequential Metathesis—Kharasch Sequences Using the Grubbs′ Metathesis Catalysts.
ChemInform, 2006Co-Authors: Christopher David Edlin, James Faulkner, Peter QuayleAbstract:Abstract Sequential ring-closing Metathesis (RCM)–Kharasch cyclizations are promoted by the Grubbs Metathesis catalysts and provide rapid access to bicyclic lactones and lactams.
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catalyst economy part 2 sequential Metathesis kharasch sequences using the Grubbs Metathesis catalysts
Tetrahedron Letters, 2006Co-Authors: Christopher David Edlin, James Faulkner, Peter QuayleAbstract:Abstract Sequential ring-closing Metathesis (RCM)–Kharasch cyclizations are promoted by the Grubbs Metathesis catalysts and provide rapid access to bicyclic lactones and lactams.
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Intramolecular Metathesis versus Kharasch reactions using the Grubbs Metathesis catalyst: towards catalyst economy
Tetrahedron Letters, 2005Co-Authors: James Faulkner, Chris D. Edlin, David Fengas, Ian Preece, Peter Quayle, Stuart N. RichardsAbstract:The first generation Grubbs catalyst can promote either ring closing Metathesis (RCM) or atom transfer radical cyclisation reactions (ATRC) depending upon the reaction conditions employed.
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A comment on the Gurjar mechanism for alkene isomerization using the Grubbs olefin Metathesis catalysts
Synlett, 2005Co-Authors: Christopher David Edlin, James Faulkner, David Fengas, Ian Preece, Peter Quayle, Christopher K. Knight, Jeremy S. Parker, Stuart N. RichardsAbstract:The mechanism of allylic alc. isomerization in the presence of the Grubbs Metathesis catalysts is discussed. [on SciFinder (R)]
