H-Y Antigen

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Barbara F. Heslop - One of the best experts on this subject based on the ideXlab platform.

  • H‐Y Antigen is not expressed on purified rat erythrocytes
    Tissue Antigens, 2008
    Co-Authors: Mark P. Bradley, Margaret A. Baird, Barbara F. Heslop
    Abstract:

    The presence of H-Y Antigen on male rat erythrocytes was investigated using a high-titre H-Y antiserum in both ELISA, cellular absorption and syngeneic male to female erythrocyte transfusion studies. No evidence was found to suggest that H-Y Antigen is expressed on rat erythrocytes. These data are in accord with recent findings of other investigators studying mouse H-Y serology.

  • H-Y Antigen is not expressed on purified rat erythrocytes.
    Tissue antigens, 2008
    Co-Authors: Mark P. Bradley, Margaret A. Baird, Barbara F. Heslop
    Abstract:

    The presence of H-Y Antigen on male rat erythrocytes was investigated using a high-titre H-Y antiserum in both ELISA, cellular absorption and syngeneic male to female erythrocyte transfusion studies. No evidence was found to suggest that H-Y Antigen is expressed on rat erythrocytes. These data are in accord with recent findings of other investigators studying mouse H-Y serology.

Mark P. Bradley - One of the best experts on this subject based on the ideXlab platform.

  • H‐Y Antigen is not expressed on purified rat erythrocytes
    Tissue Antigens, 2008
    Co-Authors: Mark P. Bradley, Margaret A. Baird, Barbara F. Heslop
    Abstract:

    The presence of H-Y Antigen on male rat erythrocytes was investigated using a high-titre H-Y antiserum in both ELISA, cellular absorption and syngeneic male to female erythrocyte transfusion studies. No evidence was found to suggest that H-Y Antigen is expressed on rat erythrocytes. These data are in accord with recent findings of other investigators studying mouse H-Y serology.

  • H-Y Antigen is not expressed on purified rat erythrocytes.
    Tissue antigens, 2008
    Co-Authors: Mark P. Bradley, Margaret A. Baird, Barbara F. Heslop
    Abstract:

    The presence of H-Y Antigen on male rat erythrocytes was investigated using a high-titre H-Y antiserum in both ELISA, cellular absorption and syngeneic male to female erythrocyte transfusion studies. No evidence was found to suggest that H-Y Antigen is expressed on rat erythrocytes. These data are in accord with recent findings of other investigators studying mouse H-Y serology.

Margaret A. Baird - One of the best experts on this subject based on the ideXlab platform.

  • H‐Y Antigen is not expressed on purified rat erythrocytes
    Tissue Antigens, 2008
    Co-Authors: Mark P. Bradley, Margaret A. Baird, Barbara F. Heslop
    Abstract:

    The presence of H-Y Antigen on male rat erythrocytes was investigated using a high-titre H-Y antiserum in both ELISA, cellular absorption and syngeneic male to female erythrocyte transfusion studies. No evidence was found to suggest that H-Y Antigen is expressed on rat erythrocytes. These data are in accord with recent findings of other investigators studying mouse H-Y serology.

  • H-Y Antigen is not expressed on purified rat erythrocytes.
    Tissue antigens, 2008
    Co-Authors: Mark P. Bradley, Margaret A. Baird, Barbara F. Heslop
    Abstract:

    The presence of H-Y Antigen on male rat erythrocytes was investigated using a high-titre H-Y antiserum in both ELISA, cellular absorption and syngeneic male to female erythrocyte transfusion studies. No evidence was found to suggest that H-Y Antigen is expressed on rat erythrocytes. These data are in accord with recent findings of other investigators studying mouse H-Y serology.

Usha Athreya - One of the best experts on this subject based on the ideXlab platform.

  • H-Y Antigen in human intersexuality.
    Clinical genetics, 2008
    Co-Authors: S. N. Ghosh, P. N. Shah, H. M. Gharpure, Usha Athreya
    Abstract:

    The status of H-Y Antigen was studied in 10 intersexual cases (three pure gonadal dysgenesis with XY genotype, three Klinefelter's syndrome, two true hermaphroditism with XX genotype, two male hermaphroditism) and in 18 normal adult subjects (nine males and nine females). In all these subjects, fluorescent staining and G-banding on chromosomes from cultured leukocytes confirmed their karyotype. Interestingly, H-Y Antigen was found to be negative in XY females with dysgenetic gonads (PGD), while in the remaining intersexual states (viz Klinefelter's syndrome, true hermaphroditism and male hermaphroditism), it was found to be positive. These observations confirm that morphological differentiation of testis is controlled by H-Y Antigen, and indicate that in the absence of the H-Y Antigen, the gonad in pure gonadal dysgenetic patients (46, XY) could not be differentiated into testis, Further, it appears that H-Y Antigen in no way influences the secretory function of testis.

S. N. Ghosh - One of the best experts on this subject based on the ideXlab platform.

  • H-Y Antigen in human intersexuality.
    Clinical genetics, 2008
    Co-Authors: S. N. Ghosh, P. N. Shah, H. M. Gharpure, Usha Athreya
    Abstract:

    The status of H-Y Antigen was studied in 10 intersexual cases (three pure gonadal dysgenesis with XY genotype, three Klinefelter's syndrome, two true hermaphroditism with XX genotype, two male hermaphroditism) and in 18 normal adult subjects (nine males and nine females). In all these subjects, fluorescent staining and G-banding on chromosomes from cultured leukocytes confirmed their karyotype. Interestingly, H-Y Antigen was found to be negative in XY females with dysgenetic gonads (PGD), while in the remaining intersexual states (viz Klinefelter's syndrome, true hermaphroditism and male hermaphroditism), it was found to be positive. These observations confirm that morphological differentiation of testis is controlled by H-Y Antigen, and indicate that in the absence of the H-Y Antigen, the gonad in pure gonadal dysgenetic patients (46, XY) could not be differentiated into testis, Further, it appears that H-Y Antigen in no way influences the secretory function of testis.