Haematological

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Rakpong Petkam - One of the best experts on this subject based on the ideXlab platform.

  • Toxicity of Neem Leaf Extracts (Azadirachta indica A. Juss) on Some Haematological, Ionoregulatory, Biochemical and Enzymological Parameters of Indian Major Carp, Cirrhinus mrigala
    2016
    Co-Authors: Manoharan Saravanan, Mathan Ramesh, Annamalai Malarvizhi, Rakpong Petkam
    Abstract:

    In the present study, the median lethal concentration (LC 50) of neem leaf extract to Cirrhinus mrigala for 24 h was found to be 1.035 g l-l. During the study period, the Haematological parameters including Hb, Hct, RBC, MCV, MCH and MCHC levels were significantly decreased in neem leaf extract exposed fish when compared to the control fish whereas WBC count was increased. Similarly, plasma Na+ and Cl- levels were significantly lower and K+ level were significantly higher when compared to the control. In biochemical study, elevated plasma glucose and induced protein levels were noticed. The enzymes, glutamate oxaloacetate transaminase (GOT) and glutamate pyruvate transaminase (GPT) activities were increased significantly in gill, liver and muscle of treated fish compared to that of their control groups. The results of the present investigation suggest that neem leaf extracts affects the hematological, ionoregulatory, biochemical and enzymological parameters of fish and alterations of these parameters can be useful in environmental biomonitoring of neem based products in freshwater environment

  • toxicity of neem leaf extracts azadirachta indica a juss on some Haematological ionoregulatory biochemical and enzymological parameters of indian major carp cirrhinus mrigala
    Journal of Tropical Forestry, 2011
    Co-Authors: Manoharan Saravanan, Mathan Ramesh, Annamalai Malarvizhi, Rakpong Petkam
    Abstract:

    In the present study, the median lethal concentration (LC 50) of neem leaf extract to Cirrhinus mrigala for 24 h was found to be 1.035 g l-l. During the study period, the Haematological parameters including Hb, Hct, RBC, MCV, MCH and MCHC levels were significantly decreased in neem leaf extract exposed fish when compared to the control fish whereas WBC count was increased. Similarly, plasma Na+ and Cl- levels were significantly lower and K+ level were significantly higher when compared to the control. In biochemical study, elevated plasma glucose and induced protein levels were noticed. The enzymes, glutamate oxaloacetate transaminase (GOT) and glutamate pyruvate transaminase (GPT) activities were increased significantly in gill, liver and muscle of treated fish compared to that of their control groups. The results of the present investigation suggest that neem leaf extracts affects the hematological, ionoregulatory, biochemical and enzymological parameters of fish and alterations of these parameters can be useful in environmental biomonitoring of neem based products in freshwater environment. Keywords: Azadirachta indica, Acute toxicity, Cirrhinus mrigala, Haematology, Ion regulation, Biochemical and Enzymological parameters.

Eve Roman - One of the best experts on this subject based on the ideXlab platform.

Manoharan Saravanan - One of the best experts on this subject based on the ideXlab platform.

  • Toxicity of Neem Leaf Extracts (Azadirachta indica A. Juss) on Some Haematological, Ionoregulatory, Biochemical and Enzymological Parameters of Indian Major Carp, Cirrhinus mrigala
    2016
    Co-Authors: Manoharan Saravanan, Mathan Ramesh, Annamalai Malarvizhi, Rakpong Petkam
    Abstract:

    In the present study, the median lethal concentration (LC 50) of neem leaf extract to Cirrhinus mrigala for 24 h was found to be 1.035 g l-l. During the study period, the Haematological parameters including Hb, Hct, RBC, MCV, MCH and MCHC levels were significantly decreased in neem leaf extract exposed fish when compared to the control fish whereas WBC count was increased. Similarly, plasma Na+ and Cl- levels were significantly lower and K+ level were significantly higher when compared to the control. In biochemical study, elevated plasma glucose and induced protein levels were noticed. The enzymes, glutamate oxaloacetate transaminase (GOT) and glutamate pyruvate transaminase (GPT) activities were increased significantly in gill, liver and muscle of treated fish compared to that of their control groups. The results of the present investigation suggest that neem leaf extracts affects the hematological, ionoregulatory, biochemical and enzymological parameters of fish and alterations of these parameters can be useful in environmental biomonitoring of neem based products in freshwater environment

  • toxicity of neem leaf extracts azadirachta indica a juss on some Haematological ionoregulatory biochemical and enzymological parameters of indian major carp cirrhinus mrigala
    Journal of Tropical Forestry, 2011
    Co-Authors: Manoharan Saravanan, Mathan Ramesh, Annamalai Malarvizhi, Rakpong Petkam
    Abstract:

    In the present study, the median lethal concentration (LC 50) of neem leaf extract to Cirrhinus mrigala for 24 h was found to be 1.035 g l-l. During the study period, the Haematological parameters including Hb, Hct, RBC, MCV, MCH and MCHC levels were significantly decreased in neem leaf extract exposed fish when compared to the control fish whereas WBC count was increased. Similarly, plasma Na+ and Cl- levels were significantly lower and K+ level were significantly higher when compared to the control. In biochemical study, elevated plasma glucose and induced protein levels were noticed. The enzymes, glutamate oxaloacetate transaminase (GOT) and glutamate pyruvate transaminase (GPT) activities were increased significantly in gill, liver and muscle of treated fish compared to that of their control groups. The results of the present investigation suggest that neem leaf extracts affects the hematological, ionoregulatory, biochemical and enzymological parameters of fish and alterations of these parameters can be useful in environmental biomonitoring of neem based products in freshwater environment. Keywords: Azadirachta indica, Acute toxicity, Cirrhinus mrigala, Haematology, Ion regulation, Biochemical and Enzymological parameters.

Bo Liang - One of the best experts on this subject based on the ideXlab platform.

  • COVID-19 in persons with Haematological cancers.
    Leukemia, 2020
    Co-Authors: Lei Chen, Guolin Yuan, Yun Fang, Wenlan Chen, Li Zi-chen, Bo Liang
    Abstract:

    Infection with SARS-CoV-2, the cause of coronavirus infectious disease-19 (COVID-19), has caused a pandemic with >850,000 cases worldwide and increasing. Several studies report outcomes of COVID-19 in predominately well persons. There are also some data on COVID-19 in persons with predominately solid cancer but controversy whether these persons have the same outcomes. We conducted a cohort study at two centres in Wuhan, China, of 128 hospitalised subjects with Haematological cancers, 13 (10%) of whom developed COVID-19. We also studied 226 health care providers, 16 of whom developed COVID-19 and 11 of whom were hospitalised. Co-variates were compared with the 115 subjects with Haematological cancers without COVID-19 and with 11 hospitalised health care providers with COVID-19. There were no significant differences in baseline co-variates between subjects with Haematological cancers developing or not developing COVID-19. Case rates for COVID-19 in hospitalised subjects with Haematological cancers was 10% (95% Confidence Interval [CI], 6, 17%) compared with 7% (4, 12%; P = 0.322) in health care providers. However, the 13 subjects with Haematological cancers had more severe COVID-19 and more deaths compared with hospitalised health care providers with COVID-19. Case fatality rates were 62% (32, 85%) and 0 (0, 32%; P = 0.002). Hospitalised persons with Haematological cancers have a similar case rate of COVID-19 compared with normal health care providers but have more severe disease and a higher case fatality rate. Because we were unable to identify specific risk factors for COVID-19 in hospitalised persons with Haematological cancers, we suggest increased surveillance and possible protective isolation.

Veronika Piackova - One of the best experts on this subject based on the ideXlab platform.

  • Effects of 2-phenoxyethanol Anaesthesia on Haematological Profile on Common Carp ( Cyprinus carpio ) and Rainbow Trout ( Oncorhynchus mykiss )
    Acta Veterinaria Brno, 2007
    Co-Authors: Jan Velíšek, Zdenka Svobodova, Veronika Piackova
    Abstract:

    Velisek J., Z. Svobodova, V. Piackova: Effects of 2-Phenoxyethanol Anaesthesia on Haematological Profi le on Common Carp (Cyprinus carpio) and Rainbow Trout (Oncorhynchus mykiss). Acta Vet. Brno 2007, 76: 487-492. The aim of this study was to assess changes in Haematological profi le of common carp (Cyprinus carpio) and rainbow trout (Oncorhynchus mykiss) after the exposure to anaesthetic 2-phenoxyethanol. The Haematological profi le was assessed before, immediately after 10 min of anaesthesia and 24 h after the anaesthesia with recommended concentration of 0.30 ml·l-1 2-phenoxyethanol. The 10-min exposure to 2-phenoxyethanol of common carp caused the signifi cant increase (p < 0.01) in the haematocrit value and relative and actual count of monocytes immediately after the anaesthesia. These values returned back to normal within 24 hours. In rainbow trout, 2-phenoxyethanol anaesthesia had no effect on the Haematological profi le. Results of the examinations suggest that the use of 2-phenoxyethanol at the concentration of 0.30 ml·l -1

  • effects of clove oil anaesthesia on rainbow trout oncorhynchus mykiss
    Acta Veterinaria Brno, 2005
    Co-Authors: Jan Velíšek, Zdenka Svobodova, Veronika Piackova
    Abstract:

    Veli‰ek J., Z. Svobodova, V. Piaakova: Effects of Clove Oil Anaesthesia on Rainbow Trout (Oncorhynchus mykiss). Acta Vet. Brno 2005, 74: 139-146. The aim of the study was to investigate acute toxicity of clove oil for rainbow trout and, using values of Haematological and biochemical profiles of blood and histological tissue examinations, to assess the effects of the fish exposure to that anaesthetic. Acute toxicity values of clove oil for rainbow trout found were 10 min LC50 81.1 mg·l -1 ; 10 min LC0.1 63.9 mg·l -1 ; 10 min LC99.9 100.1 mg·l-1; 96 h LC50 14.1 mg·l-1; 96 h LC0.1 12.5 mg·l-1, and 96 h LC99.9 16.2 mg·l-1. Clove oil anaesthesia had no effect on the heamatological profile of blood. A significant increase in the concentration of glucose (GLU) and ammonia (NH 3 ), and a significant decrease in the aspartate aminotransferase (AST) activity following a 10 min anaesthesia were found. A significantly decreased AST activity was also found 24 h after anaesthesia. Clove oil anaesthesia had no effect on other biochemical indices. Histological examination of the fish following anaesthesia revealed sporadic ectasia in gill lamellae 24 h after anaesthesia in 20% of fish. No histopathological changes were demonstrated in other tissues (liver, spleen, cranial and caudal kidneys). Results of the examinations suggest that the use of clove oil at a concentration of 30 mg·l -1 does