The Experts below are selected from a list of 4005 Experts worldwide ranked by ideXlab platform
Pascal Kintz - One of the best experts on this subject based on the ideXlab platform.
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variability of opiates concentrations in human Hair according to their anatomical origin head axillary and pubic regions
1993Co-Authors: P Mangin, Pascal KintzAbstract:The concentrations of morphine and codeine were investigated in Hair from the head, axillary and pubic regions obtained from 20 fatal heroin cases. Hair Preparation involves decontamination procedure in dichloromethane at 37 degrees C for 15 min, solubilization in sodium hydroxide at 100 degrees C for 5 min, neutralization with hydrochloric acid and centrifugation. After extraction in chloroform/isopropanol/n-heptane (50:17:33; v/v) at pH 9.2, drugs were derivatized with BSTFA + 1% TMCS and separated on a 12-m BP-5 capillary column. Quantification was done by GC/MS using selected ion monitoring. The highest morphine concentrations were found in public Hair (0.80-41.34 ng/mg), followed by Hair of the head (0.62-27.10 ng/mg), and axillary Hair (0.40-24.20 ng/mg). Codeine was also detected in all samples, and the codeine/morphine ratios ranged from 0.54 to 0.273. The differences observed in drug concentration in the three kinds of Hair are discussed in the light of the existing literature.
Heesun Chung - One of the best experts on this subject based on the ideXlab platform.
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correlation of methamphetamine results and concentrations between head axillary and pubic Hair
2005Co-Authors: Wonkyung Yang, Yonghoon Park, Heesun ChungAbstract:Abstract This study was designed to compare the qualitative results and concentrations of methamphetamine (MA) and its metabolite amphetamine (AP) in head Hair and Hair collected from different parts of the body (axillae and pubis). Hair from subjects ( N =14) suspected MA users was simultaneously collected. Hair Preparation involved washing step, fine cutting, overnight extraction, derivatization by the trifluoroacetic anhydride, and gas chromatography/mass spectrometry (GC/MS) using selective ion monitoring. In this study, we found a good correlation of the qualitative results for MA between head Hair and Hair on other parts of the body, but there were some differences in concentrations of MA and AP. Namely, the concentrations of MA and AP were higher in axillary and pubic Hair than in head Hair.
P Mangin - One of the best experts on this subject based on the ideXlab platform.
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variability of opiates concentrations in human Hair according to their anatomical origin head axillary and pubic regions
1993Co-Authors: P Mangin, Pascal KintzAbstract:The concentrations of morphine and codeine were investigated in Hair from the head, axillary and pubic regions obtained from 20 fatal heroin cases. Hair Preparation involves decontamination procedure in dichloromethane at 37 degrees C for 15 min, solubilization in sodium hydroxide at 100 degrees C for 5 min, neutralization with hydrochloric acid and centrifugation. After extraction in chloroform/isopropanol/n-heptane (50:17:33; v/v) at pH 9.2, drugs were derivatized with BSTFA + 1% TMCS and separated on a 12-m BP-5 capillary column. Quantification was done by GC/MS using selected ion monitoring. The highest morphine concentrations were found in public Hair (0.80-41.34 ng/mg), followed by Hair of the head (0.62-27.10 ng/mg), and axillary Hair (0.40-24.20 ng/mg). Codeine was also detected in all samples, and the codeine/morphine ratios ranged from 0.54 to 0.273. The differences observed in drug concentration in the three kinds of Hair are discussed in the light of the existing literature.
Wonkyung Yang - One of the best experts on this subject based on the ideXlab platform.
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correlation of methamphetamine results and concentrations between head axillary and pubic Hair
2005Co-Authors: Wonkyung Yang, Yonghoon Park, Heesun ChungAbstract:Abstract This study was designed to compare the qualitative results and concentrations of methamphetamine (MA) and its metabolite amphetamine (AP) in head Hair and Hair collected from different parts of the body (axillae and pubis). Hair from subjects ( N =14) suspected MA users was simultaneously collected. Hair Preparation involved washing step, fine cutting, overnight extraction, derivatization by the trifluoroacetic anhydride, and gas chromatography/mass spectrometry (GC/MS) using selective ion monitoring. In this study, we found a good correlation of the qualitative results for MA between head Hair and Hair on other parts of the body, but there were some differences in concentrations of MA and AP. Namely, the concentrations of MA and AP were higher in axillary and pubic Hair than in head Hair.
Yonghoon Park - One of the best experts on this subject based on the ideXlab platform.
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correlation of methamphetamine results and concentrations between head axillary and pubic Hair
2005Co-Authors: Wonkyung Yang, Yonghoon Park, Heesun ChungAbstract:Abstract This study was designed to compare the qualitative results and concentrations of methamphetamine (MA) and its metabolite amphetamine (AP) in head Hair and Hair collected from different parts of the body (axillae and pubis). Hair from subjects ( N =14) suspected MA users was simultaneously collected. Hair Preparation involved washing step, fine cutting, overnight extraction, derivatization by the trifluoroacetic anhydride, and gas chromatography/mass spectrometry (GC/MS) using selective ion monitoring. In this study, we found a good correlation of the qualitative results for MA between head Hair and Hair on other parts of the body, but there were some differences in concentrations of MA and AP. Namely, the concentrations of MA and AP were higher in axillary and pubic Hair than in head Hair.
