The Experts below are selected from a list of 6 Experts worldwide ranked by ideXlab platform
Richmond Sarpong - One of the best experts on this subject based on the ideXlab platform.
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Direct Methoxypyridine Functionalization Approach to Magellanine-Type Lycopodium Alkaloids
Organic Letters, 2011Co-Authors: Rebecca A. Murphy, Richmond SarpongAbstract:A concise enantioselective approach to the tetracyclic core of the magellanine-type Lycopodium alkaloids is reported. Key to this approach is the use of the Hajos–Parrish Reaction to set a challenging quaternary stereocenter, thereby guiding the stereoselectivity for the remainder of the synthesis, as well as the use of a palladium-mediated direct pyridine functionalization Reaction to forge the tetracyclic core.
Rebecca A. Murphy - One of the best experts on this subject based on the ideXlab platform.
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Direct Methoxypyridine Functionalization Approach to Magellanine-Type Lycopodium Alkaloids
Organic Letters, 2011Co-Authors: Rebecca A. Murphy, Richmond SarpongAbstract:A concise enantioselective approach to the tetracyclic core of the magellanine-type Lycopodium alkaloids is reported. Key to this approach is the use of the Hajos–Parrish Reaction to set a challenging quaternary stereocenter, thereby guiding the stereoselectivity for the remainder of the synthesis, as well as the use of a palladium-mediated direct pyridine functionalization Reaction to forge the tetracyclic core.
Alexander J. A. Cobb - One of the best experts on this subject based on the ideXlab platform.
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General Aspects of Organocatalytic Cyclizations
Enantioselective Organocatalyzed Reactions II, 2011Co-Authors: Alexander J. A. CobbAbstract:Ring-forming Reactions are an essential part of synthetic chemistry and allow access to a range of useful natural products and biologically important molecules. The applications of organocatalysis to the synthesis of functionalised, enantiopure structures really begins where organocatalysis itself begins; with the Hajos-Parrish Reaction in the 1970s for the synthesis of steroids using proline. This chapter then will review the uses of organocatalysts in cyclization methodology – from the initial Hajos-Parrish discovery to current advances in the field.
