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Stefan Renvert - One of the best experts on this subject based on the ideXlab platform.
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the long term effect of a zinc acetate and chlorhexidine diacetate containing mouth rinse on intra oral Halitosis a randomized clinical trial
Journal of Clinical Periodontology, 2017Co-Authors: Seida Erovic Ademovski, Carina Märtensson, Stefan Renvert, Gösta Rutger PerssonAbstract:Aim To evaluate the long-term effects of a zinc acetate and chlorhexidine diacetate mouth rinse (Zn/CHX) on intra-oral Halitosis. Materials and Methods Forty-six adults with intra-oral Halitosis were randomized into a 6-month, double-blind, placebo-controlled clinical study. The presence of intra-oral Halitosis was evaluated at baseline, 3, and 6 months after treatment by assessment of organoleptic score (OLS) and by total volatile sulphur compounds (T-VSC), hydrogen sulphide (H2S) and methyl mercaptan (MM) concentrations in exhaled air. Results A Zn/CHX mouth rinse provided significantly better control of intra-oral Halitosis than a placebo mouth rinse. At three and six months, individuals rinsing with the Zn/CHX rinse presented with reductions of the OLS, T-VSC (p<0.01, respectively), H2S (p<0.001), and MM (p<0.01) in subjects’ exhaled air. At 6 months 68.2% of individuals using the Zn/CHX rinse experienced a 1 or 2 category improvement in OLS compared with 19.1% of placebo-treated subjects. 91% of subjects in the Zn/CHX group were categorized as being effectively treated for intra-oral Halitosis (i.e. H2S < 112 ppb), compared to 43% in the placebo group. Conclusion Zn/CHX mouth rinse provides effective long-term efficacy against intra-oral Halitosis, assessed both objectively and subjectively. With regular rinsing, the effect was sustained for 6 months. This article is protected by copyright. All rights reserved.
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The long-term effect of a zinc acetate and chlorhexidine diacetate containing mouth rinse on intra-oral Halitosis—A randomized clinical trial
Journal of Clinical Periodontology, 2017Co-Authors: Seida Erovic Ademovski, Carina Märtensson, Gösta Rutger Persson, Stefan RenvertAbstract:AIM To evaluate the long-term effects of a zinc acetate and chlorhexidine diacetate mouth rinse (Zn/CHX) on intra-oral Halitosis. MATERIALS AND METHODS Forty-six adults with intra-oral Halitosis were randomized into a 6-month, double-blind, placebo-controlled clinical study. The presence of intra-oral Halitosis was evaluated at baseline, 3 and 6 months after treatment by assessment of organoleptic score (OLS) and by total volatile sulphur compounds (T-VSC), hydrogen sulphide (H2S) and methyl mercaptan (MM) concentrations in exhaled air. RESULTS A Zn/CHX mouth rinse provided significantly better control of intra-oral Halitosis than a placebo mouth rinse. At 3 and 6 months, individuals rinsing with the Zn/CHX rinse presented with reductions of the OLS, T-VSC (p
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The effect of periodontal therapy on intra-oral Halitosis: A case series
Journal of Clinical Periodontology, 2016Co-Authors: Seida Erovic Ademovski, Carina Märtensson, G. Rutger Persson, Stefan RenvertAbstract:AIM The aim of this study was to evaluate the effects of non-surgical periodontal therapy on intra-oral Halitosis 3 months after therapy. MATERIAL AND METHODS Sixty-eight adults with intra-oral Halitosis were included in a case series. Intra-oral Halitosis was evaluated at baseline, and at 3 months after treatment using the organoleptic scores (OLS), Halimeter®, and a gas chromatograph. RESULTS Significant reductions for OLS (p
E G Winkel - One of the best experts on this subject based on the ideXlab platform.
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extra oral Halitosis an overview
Journal of Breath Research, 2010Co-Authors: A Tangerman, E G WinkelAbstract:Halitosis can be subdivided into intra-oral and extra-oral Halitosis, depending on the place where it originates. Most reports now agree that the most frequent sources of Halitosis exist within the oral cavity and include bacterial reservoirs such as the dorsum of the tongue, saliva and periodontal pockets, where anaerobic bacteria degrade sulfur-containing amino acids to produce the foul smelling volatile sulfur compounds (VSCs), especially hydrogen sulfide (H2S) and methyl mercaptan (CH3SH). Tongue coating is considered to be the most important source of VSCs. Oral malodor can now be treated effectively. Special attention in this overview is given to extra-oral Halitosis. Extra-oral Halitosis can be subdivided into non-blood-borne Halitosis, such as Halitosis from the upper respiratory tract including the nose and from the lower respiratory tract, and blood-borne Halitosis. The majority of patients with extra-oral Halitosis have blood-borne Halitosis. Blood-borne Halitosis is also frequently caused by odorous VSCs, in particular dimethyl sulfide (CH3SCH3). Extra-oral Halitosis, covering about 5?10% of all cases of Halitosis, might be a manifestation of a serious disease for which treatment is much more complicated than for intra-oral Halitosis. It is therefore of utmost importance to differentiate between intra-oral and extra-oral Halitosis. Differences between intra-oral and extra-oral Halitosis are discussed extensively. The importance of applying odor characterization of various odorants in Halitosis research is also highlighted in this article. The use of the odor index, odor threshold values and simulation of bad breath samples is explained.
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the portable gas chromatograph oralchroma a method of choice to detect oral and extra oral Halitosis
Journal of Breath Research, 2008Co-Authors: A Tangerman, E G WinkelAbstract:It is now generally accepted that the volatile sulfur compounds (VSCs) hydrogen sulfide, methyl mercaptan and dimethyl sulfide are the main contributors to Halitosis when of oropharyngeal origin. Gas chromatography using a specific sulfur detector is the most appropriate method to detect Halitosis of different origin (intra-oral and extra-oral Halitosis) and should be considered as the gold standard. However, a gas chromatograph is an expensive apparatus and needs trained personnel. The less specific Halimeter is the most used apparatus in Halitosis research. In this study a newly developed portable gas chromatograph, the OralChroma™ (Abilit Corporation, Japan), was evaluated for use in the field of Halitosis. The results show that the OralChroma is a very sensitive apparatus for measuring VSCs. Just like standard gas chromatography, it can perfectly differentiate between intra-oral and extra-oral blood-borne Halitosis, while the Halimeter can only detect intra-oral Halitosis. The hardware of the OralChroma meets all the needs for becoming the apparatus of choice in the field of Halitosis. However, the software needs a major revision. Sometimes, the concentrations given for the different VSCs are completely incorrect due to a wrong assignment of the place of the VSCs in the chromatogram.
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intra and extra oral Halitosis finding of a new form of extra oral blood borne Halitosis caused by dimethyl sulphide
Journal of Clinical Periodontology, 2007Co-Authors: A Tangerman, E G WinkelAbstract:AIM: The aim of this study was to unravel the origen and cause of intra-oral and extra-oral Halitosis. MATERIAL AND METHODS: We studied 58 patients complaining of Halitosis, using gas chromatography of volatile sulphur compounds (VSCs) in mouth and nose breath, organoleptic scoring of mouth and nose breath, Halimeter readings of mouth air and tongue-coating inspection. Subjects had no precence or history of periodontitis. RESULT: Of 58 patients, 47 patients had Halitosis of oral origin, six had Halitosis of extra-oral origin and five had no Halitosis (halitophobia). A strong correlation was found between the degree of intra-oral Halitosis as measured by organoleptic scoring of mouth breath and the concentration of the VSCs hydrogen sulphide (H(2)S) and methyl mercaptan (CH(3)SH) in mouth breath. Taking into account the much larger odour index of CH(3)SH, it was concluded that CH(3)SH is the main contributor to intra-oral Halitosis. In all six cases of extra-oral Halitosis, Halitosis was caused by the presence of elevated levels of dimethyl sulphide (CH(3)SCH(3)) in mouth and nose breath. CONCLUSION: Our study provides evidence that the VSC, CH(3)SH and to a lesser extent H(2)S are the main contributors to intra-oral Halitosis and that CH(3)SCH(3) is the main contributor to extra-oral or blood-borne Halitosis, due to a hitherto unknown metabolic disorder.
Carina Märtensson - One of the best experts on this subject based on the ideXlab platform.
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the long term effect of a zinc acetate and chlorhexidine diacetate containing mouth rinse on intra oral Halitosis a randomized clinical trial
Journal of Clinical Periodontology, 2017Co-Authors: Seida Erovic Ademovski, Carina Märtensson, Stefan Renvert, Gösta Rutger PerssonAbstract:Aim To evaluate the long-term effects of a zinc acetate and chlorhexidine diacetate mouth rinse (Zn/CHX) on intra-oral Halitosis. Materials and Methods Forty-six adults with intra-oral Halitosis were randomized into a 6-month, double-blind, placebo-controlled clinical study. The presence of intra-oral Halitosis was evaluated at baseline, 3, and 6 months after treatment by assessment of organoleptic score (OLS) and by total volatile sulphur compounds (T-VSC), hydrogen sulphide (H2S) and methyl mercaptan (MM) concentrations in exhaled air. Results A Zn/CHX mouth rinse provided significantly better control of intra-oral Halitosis than a placebo mouth rinse. At three and six months, individuals rinsing with the Zn/CHX rinse presented with reductions of the OLS, T-VSC (p<0.01, respectively), H2S (p<0.001), and MM (p<0.01) in subjects’ exhaled air. At 6 months 68.2% of individuals using the Zn/CHX rinse experienced a 1 or 2 category improvement in OLS compared with 19.1% of placebo-treated subjects. 91% of subjects in the Zn/CHX group were categorized as being effectively treated for intra-oral Halitosis (i.e. H2S < 112 ppb), compared to 43% in the placebo group. Conclusion Zn/CHX mouth rinse provides effective long-term efficacy against intra-oral Halitosis, assessed both objectively and subjectively. With regular rinsing, the effect was sustained for 6 months. This article is protected by copyright. All rights reserved.
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The long-term effect of a zinc acetate and chlorhexidine diacetate containing mouth rinse on intra-oral Halitosis—A randomized clinical trial
Journal of Clinical Periodontology, 2017Co-Authors: Seida Erovic Ademovski, Carina Märtensson, Gösta Rutger Persson, Stefan RenvertAbstract:AIM To evaluate the long-term effects of a zinc acetate and chlorhexidine diacetate mouth rinse (Zn/CHX) on intra-oral Halitosis. MATERIALS AND METHODS Forty-six adults with intra-oral Halitosis were randomized into a 6-month, double-blind, placebo-controlled clinical study. The presence of intra-oral Halitosis was evaluated at baseline, 3 and 6 months after treatment by assessment of organoleptic score (OLS) and by total volatile sulphur compounds (T-VSC), hydrogen sulphide (H2S) and methyl mercaptan (MM) concentrations in exhaled air. RESULTS A Zn/CHX mouth rinse provided significantly better control of intra-oral Halitosis than a placebo mouth rinse. At 3 and 6 months, individuals rinsing with the Zn/CHX rinse presented with reductions of the OLS, T-VSC (p
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The effect of periodontal therapy on intra-oral Halitosis: A case series
Journal of Clinical Periodontology, 2016Co-Authors: Seida Erovic Ademovski, Carina Märtensson, G. Rutger Persson, Stefan RenvertAbstract:AIM The aim of this study was to evaluate the effects of non-surgical periodontal therapy on intra-oral Halitosis 3 months after therapy. MATERIAL AND METHODS Sixty-eight adults with intra-oral Halitosis were included in a case series. Intra-oral Halitosis was evaluated at baseline, and at 3 months after treatment using the organoleptic scores (OLS), Halimeter®, and a gas chromatograph. RESULTS Significant reductions for OLS (p
Gösta Rutger Persson - One of the best experts on this subject based on the ideXlab platform.
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the long term effect of a zinc acetate and chlorhexidine diacetate containing mouth rinse on intra oral Halitosis a randomized clinical trial
Journal of Clinical Periodontology, 2017Co-Authors: Seida Erovic Ademovski, Carina Märtensson, Stefan Renvert, Gösta Rutger PerssonAbstract:Aim To evaluate the long-term effects of a zinc acetate and chlorhexidine diacetate mouth rinse (Zn/CHX) on intra-oral Halitosis. Materials and Methods Forty-six adults with intra-oral Halitosis were randomized into a 6-month, double-blind, placebo-controlled clinical study. The presence of intra-oral Halitosis was evaluated at baseline, 3, and 6 months after treatment by assessment of organoleptic score (OLS) and by total volatile sulphur compounds (T-VSC), hydrogen sulphide (H2S) and methyl mercaptan (MM) concentrations in exhaled air. Results A Zn/CHX mouth rinse provided significantly better control of intra-oral Halitosis than a placebo mouth rinse. At three and six months, individuals rinsing with the Zn/CHX rinse presented with reductions of the OLS, T-VSC (p<0.01, respectively), H2S (p<0.001), and MM (p<0.01) in subjects’ exhaled air. At 6 months 68.2% of individuals using the Zn/CHX rinse experienced a 1 or 2 category improvement in OLS compared with 19.1% of placebo-treated subjects. 91% of subjects in the Zn/CHX group were categorized as being effectively treated for intra-oral Halitosis (i.e. H2S < 112 ppb), compared to 43% in the placebo group. Conclusion Zn/CHX mouth rinse provides effective long-term efficacy against intra-oral Halitosis, assessed both objectively and subjectively. With regular rinsing, the effect was sustained for 6 months. This article is protected by copyright. All rights reserved.
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The long-term effect of a zinc acetate and chlorhexidine diacetate containing mouth rinse on intra-oral Halitosis—A randomized clinical trial
Journal of Clinical Periodontology, 2017Co-Authors: Seida Erovic Ademovski, Carina Märtensson, Gösta Rutger Persson, Stefan RenvertAbstract:AIM To evaluate the long-term effects of a zinc acetate and chlorhexidine diacetate mouth rinse (Zn/CHX) on intra-oral Halitosis. MATERIALS AND METHODS Forty-six adults with intra-oral Halitosis were randomized into a 6-month, double-blind, placebo-controlled clinical study. The presence of intra-oral Halitosis was evaluated at baseline, 3 and 6 months after treatment by assessment of organoleptic score (OLS) and by total volatile sulphur compounds (T-VSC), hydrogen sulphide (H2S) and methyl mercaptan (MM) concentrations in exhaled air. RESULTS A Zn/CHX mouth rinse provided significantly better control of intra-oral Halitosis than a placebo mouth rinse. At 3 and 6 months, individuals rinsing with the Zn/CHX rinse presented with reductions of the OLS, T-VSC (p
Seida Erovic Ademovski - One of the best experts on this subject based on the ideXlab platform.
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The long-term effect of a zinc acetate and chlorhexidine diacetate containing mouth rinse on intra-oral Halitosis—A randomized clinical trial
Journal of Clinical Periodontology, 2017Co-Authors: Seida Erovic Ademovski, Carina Märtensson, Gösta Rutger Persson, Stefan RenvertAbstract:AIM To evaluate the long-term effects of a zinc acetate and chlorhexidine diacetate mouth rinse (Zn/CHX) on intra-oral Halitosis. MATERIALS AND METHODS Forty-six adults with intra-oral Halitosis were randomized into a 6-month, double-blind, placebo-controlled clinical study. The presence of intra-oral Halitosis was evaluated at baseline, 3 and 6 months after treatment by assessment of organoleptic score (OLS) and by total volatile sulphur compounds (T-VSC), hydrogen sulphide (H2S) and methyl mercaptan (MM) concentrations in exhaled air. RESULTS A Zn/CHX mouth rinse provided significantly better control of intra-oral Halitosis than a placebo mouth rinse. At 3 and 6 months, individuals rinsing with the Zn/CHX rinse presented with reductions of the OLS, T-VSC (p
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The effect of periodontal therapy on intra-oral Halitosis: A case series
Journal of Clinical Periodontology, 2016Co-Authors: Seida Erovic Ademovski, Carina Märtensson, G. Rutger Persson, Stefan RenvertAbstract:AIM The aim of this study was to evaluate the effects of non-surgical periodontal therapy on intra-oral Halitosis 3 months after therapy. MATERIAL AND METHODS Sixty-eight adults with intra-oral Halitosis were included in a case series. Intra-oral Halitosis was evaluated at baseline, and at 3 months after treatment using the organoleptic scores (OLS), Halimeter®, and a gas chromatograph. RESULTS Significant reductions for OLS (p
