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Annemarie Uel - One of the best experts on this subject based on the ideXlab platform.

  • no effect of risedronate on articular cartilage damage in the dunkin Hartley guinea pig model of osteoarthritis
    Scandinavian Journal of Rheumatology, 2013
    Co-Authors: Jesper Skovhus Thomse, T S Straarup, Carl Christia Danielse, Hans Oxlund, Annemarie Uel
    Abstract:

    Objectives: To investigate whether treatment with a bisphosphonate would influence the subchondral bone plate stiffness and the development of cartilage damage in Dunkin Hartley guinea pigs, which develop osteoarthritis (OA) spontaneously.Method: Fifty-six 3-month-old male Dunkin Hartley guinea pigs were randomized into a baseline group and six groups receiving either the bisphosphonate risedronate (30 µg/kg) or vehicle five times a week for 6, 12, or 24 weeks. The medial condyle of the right stifle joint was investigated by histology, using the Osteoarthritis Research Society International (OARSI) score, along with static and dynamic histomorphometry. The subchondral bone plate of the left tibia was tested mechanically with indentation testing. Degradation products of C-terminal telopeptides of type II collagen (CTX-II) were measured in serum.Results: The OARSI score did not differ between risedronate-treated and control animals at any time point. The fraction of bone surfaces covered with osteoclasts (O...

  • relationship between articular cartilage damage and subchondral bone properties and meniscal ossification in the dunkin Hartley guinea pig model of osteoarthritis
    Scandinavian Journal of Rheumatology, 2011
    Co-Authors: Jesper Skovhus Thomse, T S Straarup, Carl Christia Danielse, Hans Oxlund, Annemarie Uel
    Abstract:

    Objectives: To describe the age-related changes of articular cartilage, subchondral bone morphology, and stiffness. Furthermore, to investigate whether subchondral bone histological and mechanical properties and meniscal histological properties are related to articular cartilage damage in the Dunkin Hartley guinea pig model of osteoarthritis (OA).Methods: Forty male Dunkin Hartley guinea pigs aged 2, 6, 9, and 12 months were studied. The right stifle joints and the left menisci were embedded undecalcified and the tibial articular cartilage and subchondral bone and the menisci were examined using histology. The stiffness of the left tibial subchondral bone was determined with indentation testing.Results: The Osteoarthritis Research Society International (OARSI) grade of the osteoarthritic cartilage lesions of the medial (p < 0.001) and lateral (p < 0.001) condyle and the ossification of the medial (p < 0.001) and lateral (p < 0.001) meniscus increased significantly with age and was significantly more prono...

Jesper Skovhus Thomse - One of the best experts on this subject based on the ideXlab platform.

  • no effect of risedronate on articular cartilage damage in the dunkin Hartley guinea pig model of osteoarthritis
    Scandinavian Journal of Rheumatology, 2013
    Co-Authors: Jesper Skovhus Thomse, T S Straarup, Carl Christia Danielse, Hans Oxlund, Annemarie Uel
    Abstract:

    Objectives: To investigate whether treatment with a bisphosphonate would influence the subchondral bone plate stiffness and the development of cartilage damage in Dunkin Hartley guinea pigs, which develop osteoarthritis (OA) spontaneously.Method: Fifty-six 3-month-old male Dunkin Hartley guinea pigs were randomized into a baseline group and six groups receiving either the bisphosphonate risedronate (30 µg/kg) or vehicle five times a week for 6, 12, or 24 weeks. The medial condyle of the right stifle joint was investigated by histology, using the Osteoarthritis Research Society International (OARSI) score, along with static and dynamic histomorphometry. The subchondral bone plate of the left tibia was tested mechanically with indentation testing. Degradation products of C-terminal telopeptides of type II collagen (CTX-II) were measured in serum.Results: The OARSI score did not differ between risedronate-treated and control animals at any time point. The fraction of bone surfaces covered with osteoclasts (O...

  • relationship between articular cartilage damage and subchondral bone properties and meniscal ossification in the dunkin Hartley guinea pig model of osteoarthritis
    Scandinavian Journal of Rheumatology, 2011
    Co-Authors: Jesper Skovhus Thomse, T S Straarup, Carl Christia Danielse, Hans Oxlund, Annemarie Uel
    Abstract:

    Objectives: To describe the age-related changes of articular cartilage, subchondral bone morphology, and stiffness. Furthermore, to investigate whether subchondral bone histological and mechanical properties and meniscal histological properties are related to articular cartilage damage in the Dunkin Hartley guinea pig model of osteoarthritis (OA).Methods: Forty male Dunkin Hartley guinea pigs aged 2, 6, 9, and 12 months were studied. The right stifle joints and the left menisci were embedded undecalcified and the tibial articular cartilage and subchondral bone and the menisci were examined using histology. The stiffness of the left tibial subchondral bone was determined with indentation testing.Results: The Osteoarthritis Research Society International (OARSI) grade of the osteoarthritic cartilage lesions of the medial (p < 0.001) and lateral (p < 0.001) condyle and the ossification of the medial (p < 0.001) and lateral (p < 0.001) meniscus increased significantly with age and was significantly more prono...

B Carcich - One of the best experts on this subject based on the ideXlab platform.

  • the temperature thermal inertia roughness and color of the nuclei of comets 103p Hartley 2 and 9p tempel 1
    Icarus, 2013
    Co-Authors: O Groussin, P C Thomas, Michael F Ahearn, J M Sunshine, L M Feaga, L Jorda, Jian Li, M J S Belton, S Besse, B Carcich
    Abstract:

    The Deep Impact spacecraft flew by Comet 103P/Hartley 2 on November 4th, 2010 (EPOXI mission) and Comet 9P/Tempel 1 on July 4th, 2005 (Deep Impact mission). During the two flybys, spatially resolved infrared (1.05–4.8 lm) spectra of the surface of the nucleus were acquired by the HRI-IR instrument. The analysis of these two data sets, obtained by the same instrument, offers a unique opportunity to understand, compare and contrast the surface thermal properties of these two comets. For this paper, we use spectral cubes with a spatial resolution of 30 m/pixel to 40 m/pixel for Hartley 2 and 160 m/pixel for Tempel 1. We focus our analysis on the color, temperature, thermal inertia and roughness of the nucleus.

  • the temperature thermal inertia roughness and color of the nuclei of comets 103p Hartley 2 and 9p tempel 1
    Icarus, 2013
    Co-Authors: O Groussin, P C Thomas, Michael F Ahearn, Lori M Feaga, J M Sunshine, L Jorda, M J S Belton, S Besse, B Carcich, T L Farnham
    Abstract:

    The Deep Impact spacecraft flew by Comet 103P/Hartley 2 on November 4th, 2010 (EPOXI mission) and Comet 9P/Tempel 1 on July 4th, 2005 (Deep Impact mission). During the two flybys, spatially resolved infrared (1.05–4.8 lm) spectra of the surface of the nucleus were acquired by the HRI-IR instrument. The analysis of these two data sets, obtained by the same instrument, offers a unique opportunity to understand, compare and contrast the surface thermal properties of these two comets. For this paper, we use spectral cubes with a spatial resolution of 30 m/pixel to 40 m/pixel for Hartley 2 and 160 m/pixel for Tempel 1. We focus our analysis on the color, temperature, thermal inertia and roughness of the nucleus.

J M Sunshine - One of the best experts on this subject based on the ideXlab platform.

  • comparative study of water ice exposures on cometary nuclei using multispectral imaging data
    Monthly Notices of the Royal Astronomical Society, 2016
    Co-Authors: N Oklay, J M Sunshine, M Pajola, Antoine Pommerol, J B Vincent, S Mottola, H Sierks, S Fornasier, M A Barucci
    Abstract:

    Deep Impact, EPOXI and Rosetta missions visited comets 9P/Tempel 1, 103P/Hartley 2 and 67P/Churyumov-Gerasimenko, respectively. Each of these three missions was equipped with both multispectral ima ...

  • the temperature thermal inertia roughness and color of the nuclei of comets 103p Hartley 2 and 9p tempel 1
    Icarus, 2013
    Co-Authors: O Groussin, P C Thomas, Michael F Ahearn, J M Sunshine, L M Feaga, L Jorda, Jian Li, M J S Belton, S Besse, B Carcich
    Abstract:

    The Deep Impact spacecraft flew by Comet 103P/Hartley 2 on November 4th, 2010 (EPOXI mission) and Comet 9P/Tempel 1 on July 4th, 2005 (Deep Impact mission). During the two flybys, spatially resolved infrared (1.05–4.8 lm) spectra of the surface of the nucleus were acquired by the HRI-IR instrument. The analysis of these two data sets, obtained by the same instrument, offers a unique opportunity to understand, compare and contrast the surface thermal properties of these two comets. For this paper, we use spectral cubes with a spatial resolution of 30 m/pixel to 40 m/pixel for Hartley 2 and 160 m/pixel for Tempel 1. We focus our analysis on the color, temperature, thermal inertia and roughness of the nucleus.

  • the temperature thermal inertia roughness and color of the nuclei of comets 103p Hartley 2 and 9p tempel 1
    Icarus, 2013
    Co-Authors: O Groussin, P C Thomas, Michael F Ahearn, Lori M Feaga, J M Sunshine, L Jorda, M J S Belton, S Besse, B Carcich, T L Farnham
    Abstract:

    The Deep Impact spacecraft flew by Comet 103P/Hartley 2 on November 4th, 2010 (EPOXI mission) and Comet 9P/Tempel 1 on July 4th, 2005 (Deep Impact mission). During the two flybys, spatially resolved infrared (1.05–4.8 lm) spectra of the surface of the nucleus were acquired by the HRI-IR instrument. The analysis of these two data sets, obtained by the same instrument, offers a unique opportunity to understand, compare and contrast the surface thermal properties of these two comets. For this paper, we use spectral cubes with a spatial resolution of 30 m/pixel to 40 m/pixel for Hartley 2 and 160 m/pixel for Tempel 1. We focus our analysis on the color, temperature, thermal inertia and roughness of the nucleus.

O Groussin - One of the best experts on this subject based on the ideXlab platform.

  • the temperature thermal inertia roughness and color of the nuclei of comets 103p Hartley 2 and 9p tempel 1
    Icarus, 2013
    Co-Authors: O Groussin, P C Thomas, Michael F Ahearn, J M Sunshine, L M Feaga, L Jorda, Jian Li, M J S Belton, S Besse, B Carcich
    Abstract:

    The Deep Impact spacecraft flew by Comet 103P/Hartley 2 on November 4th, 2010 (EPOXI mission) and Comet 9P/Tempel 1 on July 4th, 2005 (Deep Impact mission). During the two flybys, spatially resolved infrared (1.05–4.8 lm) spectra of the surface of the nucleus were acquired by the HRI-IR instrument. The analysis of these two data sets, obtained by the same instrument, offers a unique opportunity to understand, compare and contrast the surface thermal properties of these two comets. For this paper, we use spectral cubes with a spatial resolution of 30 m/pixel to 40 m/pixel for Hartley 2 and 160 m/pixel for Tempel 1. We focus our analysis on the color, temperature, thermal inertia and roughness of the nucleus.

  • the temperature thermal inertia roughness and color of the nuclei of comets 103p Hartley 2 and 9p tempel 1
    Icarus, 2013
    Co-Authors: O Groussin, P C Thomas, Michael F Ahearn, Lori M Feaga, J M Sunshine, L Jorda, M J S Belton, S Besse, B Carcich, T L Farnham
    Abstract:

    The Deep Impact spacecraft flew by Comet 103P/Hartley 2 on November 4th, 2010 (EPOXI mission) and Comet 9P/Tempel 1 on July 4th, 2005 (Deep Impact mission). During the two flybys, spatially resolved infrared (1.05–4.8 lm) spectra of the surface of the nucleus were acquired by the HRI-IR instrument. The analysis of these two data sets, obtained by the same instrument, offers a unique opportunity to understand, compare and contrast the surface thermal properties of these two comets. For this paper, we use spectral cubes with a spatial resolution of 30 m/pixel to 40 m/pixel for Hartley 2 and 160 m/pixel for Tempel 1. We focus our analysis on the color, temperature, thermal inertia and roughness of the nucleus.

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