The Experts below are selected from a list of 9 Experts worldwide ranked by ideXlab platform
B Saha - One of the best experts on this subject based on the ideXlab platform.
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a case of Hashimotos Encephalopathy failed to respond to steroids a case report
Journal of Neurology and Neurorehabilitation Research, 2018Co-Authors: B Bhattacharjee, S Bhattacharya, D Majumdar, S Chakraborty, B Sardar, A Naskar, M K Ghosh, Sudeshna Mallik, B SahaAbstract:A 52-year-old hypothyroid presented with episodes of seizures in last ten days with altered behavior. CT scan of brain showed cerebral atrophy and MRI of brain revealed non-specific changes. In EEG, there was slow wave pattern. CSF study showed increased cell count with all lymphocytes and raised protein with normal glucose. Anti- TPO Antibody was positive. All relevant investigations like HIV, HBsAg, Anti- HCV Ab, ANA (Hep2 method), ANA profile, P-ANCA, c-ANCA, VGKC (voltage gated potassium channel) Ab, NMDA Receptor/Anti- Glutamate Antibody) Ab, VDRL were negative. She was given pulse doses of methylprednisolone followed by maintenance prednisolone. Then her GCS improved followed by sudden deterioration. Repeat CSF showed marginal decrement of protein and cell count. Then she was given IV Immunoglobulin and patient improved. At discharge her CSF study normalized. Anti-TPO Ab titre came to normal level and EEG normalized. Hashimoto’s Encephalopathy(HE) should be suspected in a case of sub-acute Encephalopathy with high levels of anti-thyroid antibodies may be with normal thyroid functions. Here the patient did not have improvement on steroids. The patient needed immunoglobulin to improve.
B Bhattacharjee - One of the best experts on this subject based on the ideXlab platform.
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a case of Hashimotos Encephalopathy failed to respond to steroids a case report
Journal of Neurology and Neurorehabilitation Research, 2018Co-Authors: B Bhattacharjee, S Bhattacharya, D Majumdar, S Chakraborty, B Sardar, A Naskar, M K Ghosh, Sudeshna Mallik, B SahaAbstract:A 52-year-old hypothyroid presented with episodes of seizures in last ten days with altered behavior. CT scan of brain showed cerebral atrophy and MRI of brain revealed non-specific changes. In EEG, there was slow wave pattern. CSF study showed increased cell count with all lymphocytes and raised protein with normal glucose. Anti- TPO Antibody was positive. All relevant investigations like HIV, HBsAg, Anti- HCV Ab, ANA (Hep2 method), ANA profile, P-ANCA, c-ANCA, VGKC (voltage gated potassium channel) Ab, NMDA Receptor/Anti- Glutamate Antibody) Ab, VDRL were negative. She was given pulse doses of methylprednisolone followed by maintenance prednisolone. Then her GCS improved followed by sudden deterioration. Repeat CSF showed marginal decrement of protein and cell count. Then she was given IV Immunoglobulin and patient improved. At discharge her CSF study normalized. Anti-TPO Ab titre came to normal level and EEG normalized. Hashimoto’s Encephalopathy(HE) should be suspected in a case of sub-acute Encephalopathy with high levels of anti-thyroid antibodies may be with normal thyroid functions. Here the patient did not have improvement on steroids. The patient needed immunoglobulin to improve.
Arijit Singha - One of the best experts on this subject based on the ideXlab platform.
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Hashimotos Encephalopathy presenting with multiple cranial nerve palsies and hemiparesis: A case report
International Journal of Case Reports and Images, 2012Co-Authors: Santanu Saha, Riddhi Das Gupta, Adreesh Mukherjee, Arijit SinghaAbstract:Introduction: Hashimoto’s Encephalopathy is a steroidresponsive Encephalopathy associated with elevated blood concentrations of antithyroid antibodies. The patients are usually euthyroid or mildly hypothyroid. A wide array of clinical features of Hashimoto’s Encephalopathy has been reported till date. The pleomorphic manifestations may be behavioral and cognitive changes, myoclonus, seizures, pyramidal tract dysfunction, involuntary movements, cerebellar signs, psychosis and coma, with relapsing and progressive course. The diagnosis is often overlooked at presentation but is crucial, given that this is a treatable disease. Case Report: We describe a case of Hashimoto‘s Encephalopathy presenting with multiple cranial nerve palsies and right sided hemiparesis in a 32yearold male patient from West Bengal, India. Conclusion: This is the first reported case of multiple cranial nerve involvement in a case of Hashimoto’s Encephalopathy.
S Bhattacharya - One of the best experts on this subject based on the ideXlab platform.
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a case of Hashimotos Encephalopathy failed to respond to steroids a case report
Journal of Neurology and Neurorehabilitation Research, 2018Co-Authors: B Bhattacharjee, S Bhattacharya, D Majumdar, S Chakraborty, B Sardar, A Naskar, M K Ghosh, Sudeshna Mallik, B SahaAbstract:A 52-year-old hypothyroid presented with episodes of seizures in last ten days with altered behavior. CT scan of brain showed cerebral atrophy and MRI of brain revealed non-specific changes. In EEG, there was slow wave pattern. CSF study showed increased cell count with all lymphocytes and raised protein with normal glucose. Anti- TPO Antibody was positive. All relevant investigations like HIV, HBsAg, Anti- HCV Ab, ANA (Hep2 method), ANA profile, P-ANCA, c-ANCA, VGKC (voltage gated potassium channel) Ab, NMDA Receptor/Anti- Glutamate Antibody) Ab, VDRL were negative. She was given pulse doses of methylprednisolone followed by maintenance prednisolone. Then her GCS improved followed by sudden deterioration. Repeat CSF showed marginal decrement of protein and cell count. Then she was given IV Immunoglobulin and patient improved. At discharge her CSF study normalized. Anti-TPO Ab titre came to normal level and EEG normalized. Hashimoto’s Encephalopathy(HE) should be suspected in a case of sub-acute Encephalopathy with high levels of anti-thyroid antibodies may be with normal thyroid functions. Here the patient did not have improvement on steroids. The patient needed immunoglobulin to improve.
D Majumdar - One of the best experts on this subject based on the ideXlab platform.
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a case of Hashimotos Encephalopathy failed to respond to steroids a case report
Journal of Neurology and Neurorehabilitation Research, 2018Co-Authors: B Bhattacharjee, S Bhattacharya, D Majumdar, S Chakraborty, B Sardar, A Naskar, M K Ghosh, Sudeshna Mallik, B SahaAbstract:A 52-year-old hypothyroid presented with episodes of seizures in last ten days with altered behavior. CT scan of brain showed cerebral atrophy and MRI of brain revealed non-specific changes. In EEG, there was slow wave pattern. CSF study showed increased cell count with all lymphocytes and raised protein with normal glucose. Anti- TPO Antibody was positive. All relevant investigations like HIV, HBsAg, Anti- HCV Ab, ANA (Hep2 method), ANA profile, P-ANCA, c-ANCA, VGKC (voltage gated potassium channel) Ab, NMDA Receptor/Anti- Glutamate Antibody) Ab, VDRL were negative. She was given pulse doses of methylprednisolone followed by maintenance prednisolone. Then her GCS improved followed by sudden deterioration. Repeat CSF showed marginal decrement of protein and cell count. Then she was given IV Immunoglobulin and patient improved. At discharge her CSF study normalized. Anti-TPO Ab titre came to normal level and EEG normalized. Hashimoto’s Encephalopathy(HE) should be suspected in a case of sub-acute Encephalopathy with high levels of anti-thyroid antibodies may be with normal thyroid functions. Here the patient did not have improvement on steroids. The patient needed immunoglobulin to improve.
