Head-Up Tilt Test

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Ingrid B Helland - One of the best experts on this subject based on the ideXlab platform.

T. Aljama-corrales - One of the best experts on this subject based on the ideXlab platform.

  • Temporal cardiovascular causality during orthostatic stress by extended partial directed coherence
    2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019
    Co-Authors: S. Reulecke, S. Charleston-villalobos, A. Voss, R. González-camarena, M. Gaitán-gonzález, J. González-hermosillo, G. Hernández-pacheco, T. Aljama-corrales
    Abstract:

    The aim of this study was to investigate the temporal dynamic behavior of cardiovascular interactions between heart period and systolic blood pressure during a 20-min Head-Up Tilt Test at 70° in young women with orthostatic intolerance compared to healthy women. Methods included the lagged and extended partial directed coherence applied to short-term windows shifted by 5 seconds, extracted from a multivariate set of cardiovascular and respiratory time series. Findings revealed significantly increased information flow (p

  • Gender differences in cardiovascular and cardiorespiratory coupling in healthy subjects during Head-Up Tilt Test by Joint Symbolic Dynamics
    2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2014
    Co-Authors: S. Reulecke, S. Charleston-villalobos, A. Voss, R. González-camarena, J. González-hermosillo, G. Hernández-pacheco, M. J. Gaitán-gonzález, T. Aljama-corrales
    Abstract:

    Gender related-differences in the autonomic regulation of the cardiovascular and cardiorespiratory systems have been studied mainly by hemodynamic responses during different physical stressors. In this study, the influence of gender on the autonomic response to an orthostatic challenge was investigated by obtaining the cardiovascular and cardiorespiratory coupling using the nonlinear technique known as joint symbolic dynamics (JSD) representation. This study includes 24 healthy young subjects. Males (N=12) and age-matched females (N=12) were enrolled in a Head-Up Tilt (HUT) Test, breathing normally, including 5 minutes of supine position (baseline) and 25-40 minutes of 70° orthostatic phase. The cardiovascular and cardiorespiratory couplings were obtained at baseline, early and middle orthostatic phases. Although in baseline there were some gender differences, parameters from JSD showed highly significant (p=0.0004) differences in specific cardiovascular coupling patterns in the early Tilt phase. Furthermore, JSD analysis revealed that in males, due to increased sympathetic activity, exist a lower degree of cardiovascular coupling accompanied with an increased occurrence of tachycardic patterns. On the other hand, the cardiorespiratory coupling revealed only very few slightly significant differences in all three phases.

Stefano Favale - One of the best experts on this subject based on the ideXlab platform.

  • Clinical predictors of Head-Up Tilt Test outcome during the nitroglycerin phase
    Clinical Autonomic Research, 2010
    Co-Authors: Massimo Iacoviello, Pietro Guida, Cinzia Forleo, Sandro Sorrentino, Marco Matteo Ciccone, Valentina D’andria, Mariligia Panunzio, Stefano Favale
    Abstract:

    Objectives Nitrate-stimulated Head-Up Tilt Testing (HUT) is currently recommended to confirm the diagnosis of vasovagal syncope in subjects with syncope of unknown origin. Given the few data currently available, the aim of this study was to assess correlations between nitrate-induced HUT outcomes and the clinical characteristics of patients. Methods Two hundred and thirty consecutive, otherwise healthy subjects with a history of recurrent unexplained syncope underwent HUT. After 10 min supine rest, they were Tilted to 70°, and the Test was potentiated by the administration of 300 μg of nitroglycerin after 20 min. Results Out of 178 subjects who underwent nitroglycerin administration during HUT, 95 fainted. At univariate Cox regression analysis, a reduced probability of VVS occurrence after nitrates was associated with greater systolic blood pressure and body mass index values, to male gender and smoking. At multivariate Cox regression analysis, only male gender (HR = 0.61; P  = 0.039) and smoking (HR = 0.18; P  = 0.001) remained significantly associated with HUT outcomes during the pharmacological phase of the Test. Interpretation Smokers and males are less likely to faint after nitrate administration during HUT than non-smokers and females. Further studies should clarify the possibility of improving the diagnostic power of HUT in these patients.

  • Prevalence, timing, and haemodynamic correlates of prodromes in patients with vasovagal syncope induced by Head-Up Tilt Test.
    Europace, 2009
    Co-Authors: Pietro Guida, Massimo Iacoviello, Cinzia Forleo, Angela Ferrara, Sandro Sorrentino, Cataldo Balducci, Margherita Sarlo, Stefano Favale
    Abstract:

    Aims To evaluate the prevalence, timing, and haemodynamic characteristics of prodromal symptoms in patients experiencing vasovagal syncope (VVS) during a Head-Up Tilt Test (HUT) potentiated with nitroglycerin, and their relationships with those reported before spontaneous episodes. Methods and results Symptoms preceding HUT-induced syncope were recorded, together with heart rate (HR) and arterial blood pressure (BP) values, in 149 otherwise healthy and drug-free subjects with recurrent unexplained syncope. Head-Up Tilt Test significantly increase the number of patients capable of recognizing the premonitory symptoms of VVS than before spontaneous episodes (96 vs. 79%; P < 0.001). The nine most frequent symptoms were stratified into three groups on the basis of their characteristics: headache, hot flashes, and palpitations occurred more than 3 min before syncope, with a very slight reduction in BP; nausea, asthenia, diaphoresis, vertigo, and epigastric discomfort preceded syncope by 1–3 min and were associated with a slight reduction in BP; and blurred vision appeared the last minute before syncope and was characterized by the lowest BP and HR values. Conclusion In comparison with spontaneous syncopal episodes, HUT allows the more frequent recognition of prodromes also providing useful information in terms of timing and haemodynamic characteristics of symptoms that may allow more tailored patient counselling.

  • Clinical predictors of Head-Up Tilt Test outcome during the nitroglycerin phase
    Clinical Autonomic Research, 2009
    Co-Authors: Massimo Iacoviello, Pietro Guida, Cinzia Forleo, Sandro Sorrentino, Marco Matteo Ciccone, Mariligia Panunzio, Valentina D'andria, Stefano Favale
    Abstract:

    Objectives Nitrate-stimulated Head-Up Tilt Testing (HUT) is currently recommended to confirm the diagnosis of vasovagal syncope in subjects with syncope of unknown origin. Given the few data currently available, the aim of this study was to assess correlations between nitrate-induced HUT outcomes and the clinical characteristics of patients.

Vegard B Wyller - One of the best experts on this subject based on the ideXlab platform.

S. Reulecke - One of the best experts on this subject based on the ideXlab platform.

  • Temporal cardiovascular causality during orthostatic stress by extended partial directed coherence
    2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019
    Co-Authors: S. Reulecke, S. Charleston-villalobos, A. Voss, R. González-camarena, M. Gaitán-gonzález, J. González-hermosillo, G. Hernández-pacheco, T. Aljama-corrales
    Abstract:

    The aim of this study was to investigate the temporal dynamic behavior of cardiovascular interactions between heart period and systolic blood pressure during a 20-min Head-Up Tilt Test at 70° in young women with orthostatic intolerance compared to healthy women. Methods included the lagged and extended partial directed coherence applied to short-term windows shifted by 5 seconds, extracted from a multivariate set of cardiovascular and respiratory time series. Findings revealed significantly increased information flow (p

  • Gender differences in cardiovascular and cardiorespiratory coupling in healthy subjects during Head-Up Tilt Test by Joint Symbolic Dynamics
    2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2014
    Co-Authors: S. Reulecke, S. Charleston-villalobos, A. Voss, R. González-camarena, J. González-hermosillo, G. Hernández-pacheco, M. J. Gaitán-gonzález, T. Aljama-corrales
    Abstract:

    Gender related-differences in the autonomic regulation of the cardiovascular and cardiorespiratory systems have been studied mainly by hemodynamic responses during different physical stressors. In this study, the influence of gender on the autonomic response to an orthostatic challenge was investigated by obtaining the cardiovascular and cardiorespiratory coupling using the nonlinear technique known as joint symbolic dynamics (JSD) representation. This study includes 24 healthy young subjects. Males (N=12) and age-matched females (N=12) were enrolled in a Head-Up Tilt (HUT) Test, breathing normally, including 5 minutes of supine position (baseline) and 25-40 minutes of 70° orthostatic phase. The cardiovascular and cardiorespiratory couplings were obtained at baseline, early and middle orthostatic phases. Although in baseline there were some gender differences, parameters from JSD showed highly significant (p=0.0004) differences in specific cardiovascular coupling patterns in the early Tilt phase. Furthermore, JSD analysis revealed that in males, due to increased sympathetic activity, exist a lower degree of cardiovascular coupling accompanied with an increased occurrence of tachycardic patterns. On the other hand, the cardiorespiratory coupling revealed only very few slightly significant differences in all three phases.