The Experts below are selected from a list of 109371 Experts worldwide ranked by ideXlab platform
Jiirgen Triller - One of the best experts on this subject based on the ideXlab platform.
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acute lower gastrointestinal hemorrhage minimally invasive management with microcatheter embolization
Journal of Vascular and Interventional Radiology, 2008Co-Authors: R Kickuth, Henning Rattunde, Jurgen Gschossmann, Daniel Inderbitzin, K Ludwig, Jiirgen TrillerAbstract:Purpose To evaluate the efficacy of superselective embolization therapy in the management of acute lower gastrointestinal (LGI) hemorrhage, including any bleeding distal to the ligament of Treitz. Materials and Methods Between June and August 2007, 20 patients with acute LGI bleeding underwent superselective transcatheter arterial embolization (TAE) at the authors' institution. The bleeding had different causes. All patients were treated with use of microcatheters. The following embolic agents were used: microcoils ( n = 16), polyvinyl alcohol (PVA) particles ( n = 2), and a combination of microcoils and PVA particles ( n = 2). Outcome measures included technical success (complete cessation of bleeding as documented at completion angiography), clinical success (resolution of signs or symptoms of LGI bleeding within 30 days after TAE), and the rate of major and minor complications. Results The identified bleeding sources were as follows: jejunal branch, branch of middle colic artery, branch of ileocolic artery, ileal branch, branch of left colic artery, branch of sigmoid artery, branch of the superior rectal artery, and branch of the middle rectal artery. Technical success with effective control of active bleeeding was achieved in all patients (100%). Clinical success attributed to TAE was documented in 18 of the 20 patients (90%). Major complications included death due to pulmonary embolism, Heart Infarction, and multiorgan failure in the 3rd week after TAE; a procedure-related colonic Infarction occurred in one patient. A minor complication occurred in one patient who developed a groin hematoma. Conclusions Superselective embolization may be used for effective, minimally invasive control of acute LGI bleeding.
Helmy Yusuf - One of the best experts on this subject based on the ideXlab platform.
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Synthesis and Characterization of Injectable Hydrogels with Varying Collagen⁻Chitosan⁻Thymosin β4 Composition for Myocardial Infarction Therapy.
Journal of functional biomaterials, 2018Co-Authors: Achmad Dzihan Shaghiera, Prihartini Widiyanti, Helmy YusufAbstract:Thirty percent of global mortalities are caused by cardiovascular disease, and 54% of the aforementioned amount is instigated by ischemic Heart disease that triggered myocardial Infarction. Myocardial Infarction is due to blood flow cessation in certain coronary arteries that causes lack of oxygen (ischemia) and stimulates myocardial necrosis. One of the methods to treat myocardial Infarction consists in injecting cells or active biomolecules and biomaterials into Heart Infarction locations. This study aimed to investigate the characteristics of a collagen–chitosan-based hydrogel with variations in its chitosan composition. The prepared hydrogels contained thymosin β4 (Tβ4), a 43-amino acid peptide with angiogenic and cardioprotective properties which can act as a bioactive molecule for the treatment of myocardial Infarction. A morphological structure analysis showed that the hydrogels lacked interconnecting pores. All samples were not toxic on the basis of a cytotoxicity test. A histopathological anatomy test showed that the collagen–chitosan–thymosin β4 hydrogels could stimulate angiogenesis and epicardial Heart cell migration, as demonstrated by the evaluation of the number of blood vessels and the infiltration extent of myofibroblasts.
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Synthesis and Characterization of Injectable Hydrogels with Varying Collagen–Chitosan–Thymosin β4 Composition for Myocardial Infarction Therapy
MDPI AG, 2018Co-Authors: Achmad Dzihan Shaghiera, Prihartini Widiyanti, Helmy YusufAbstract:Thirty percent of global mortalities are caused by cardiovascular disease, and 54% of the aforementioned amount is instigated by ischemic Heart disease that triggered myocardial Infarction. Myocardial Infarction is due to blood flow cessation in certain coronary arteries that causes lack of oxygen (ischemia) and stimulates myocardial necrosis. One of the methods to treat myocardial Infarction consists in injecting cells or active biomolecules and biomaterials into Heart Infarction locations. This study aimed to investigate the characteristics of a collagen–chitosan-based hydrogel with variations in its chitosan composition. The prepared hydrogels contained thymosin β4 (Tβ4), a 43-amino acid peptide with angiogenic and cardioprotective properties which can act as a bioactive molecule for the treatment of myocardial Infarction. A morphological structure analysis showed that the hydrogels lacked interconnecting pores. All samples were not toxic on the basis of a cytotoxicity test. A histopathological anatomy test showed that the collagen–chitosan–thymosin β4 hydrogels could stimulate angiogenesis and epicardial Heart cell migration, as demonstrated by the evaluation of the number of blood vessels and the infiltration extent of myofibroblasts
R Kickuth - One of the best experts on this subject based on the ideXlab platform.
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acute lower gastrointestinal hemorrhage minimally invasive management with microcatheter embolization
Journal of Vascular and Interventional Radiology, 2008Co-Authors: R Kickuth, Henning Rattunde, Jurgen Gschossmann, Daniel Inderbitzin, K Ludwig, Jiirgen TrillerAbstract:Purpose To evaluate the efficacy of superselective embolization therapy in the management of acute lower gastrointestinal (LGI) hemorrhage, including any bleeding distal to the ligament of Treitz. Materials and Methods Between June and August 2007, 20 patients with acute LGI bleeding underwent superselective transcatheter arterial embolization (TAE) at the authors' institution. The bleeding had different causes. All patients were treated with use of microcatheters. The following embolic agents were used: microcoils ( n = 16), polyvinyl alcohol (PVA) particles ( n = 2), and a combination of microcoils and PVA particles ( n = 2). Outcome measures included technical success (complete cessation of bleeding as documented at completion angiography), clinical success (resolution of signs or symptoms of LGI bleeding within 30 days after TAE), and the rate of major and minor complications. Results The identified bleeding sources were as follows: jejunal branch, branch of middle colic artery, branch of ileocolic artery, ileal branch, branch of left colic artery, branch of sigmoid artery, branch of the superior rectal artery, and branch of the middle rectal artery. Technical success with effective control of active bleeeding was achieved in all patients (100%). Clinical success attributed to TAE was documented in 18 of the 20 patients (90%). Major complications included death due to pulmonary embolism, Heart Infarction, and multiorgan failure in the 3rd week after TAE; a procedure-related colonic Infarction occurred in one patient. A minor complication occurred in one patient who developed a groin hematoma. Conclusions Superselective embolization may be used for effective, minimally invasive control of acute LGI bleeding.
Achmad Dzihan Shaghiera - One of the best experts on this subject based on the ideXlab platform.
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Synthesis and Characterization of Injectable Hydrogels with Varying Collagen⁻Chitosan⁻Thymosin β4 Composition for Myocardial Infarction Therapy.
Journal of functional biomaterials, 2018Co-Authors: Achmad Dzihan Shaghiera, Prihartini Widiyanti, Helmy YusufAbstract:Thirty percent of global mortalities are caused by cardiovascular disease, and 54% of the aforementioned amount is instigated by ischemic Heart disease that triggered myocardial Infarction. Myocardial Infarction is due to blood flow cessation in certain coronary arteries that causes lack of oxygen (ischemia) and stimulates myocardial necrosis. One of the methods to treat myocardial Infarction consists in injecting cells or active biomolecules and biomaterials into Heart Infarction locations. This study aimed to investigate the characteristics of a collagen–chitosan-based hydrogel with variations in its chitosan composition. The prepared hydrogels contained thymosin β4 (Tβ4), a 43-amino acid peptide with angiogenic and cardioprotective properties which can act as a bioactive molecule for the treatment of myocardial Infarction. A morphological structure analysis showed that the hydrogels lacked interconnecting pores. All samples were not toxic on the basis of a cytotoxicity test. A histopathological anatomy test showed that the collagen–chitosan–thymosin β4 hydrogels could stimulate angiogenesis and epicardial Heart cell migration, as demonstrated by the evaluation of the number of blood vessels and the infiltration extent of myofibroblasts.
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Synthesis and Characterization of Injectable Hydrogels with Varying Collagen–Chitosan–Thymosin β4 Composition for Myocardial Infarction Therapy
MDPI AG, 2018Co-Authors: Achmad Dzihan Shaghiera, Prihartini Widiyanti, Helmy YusufAbstract:Thirty percent of global mortalities are caused by cardiovascular disease, and 54% of the aforementioned amount is instigated by ischemic Heart disease that triggered myocardial Infarction. Myocardial Infarction is due to blood flow cessation in certain coronary arteries that causes lack of oxygen (ischemia) and stimulates myocardial necrosis. One of the methods to treat myocardial Infarction consists in injecting cells or active biomolecules and biomaterials into Heart Infarction locations. This study aimed to investigate the characteristics of a collagen–chitosan-based hydrogel with variations in its chitosan composition. The prepared hydrogels contained thymosin β4 (Tβ4), a 43-amino acid peptide with angiogenic and cardioprotective properties which can act as a bioactive molecule for the treatment of myocardial Infarction. A morphological structure analysis showed that the hydrogels lacked interconnecting pores. All samples were not toxic on the basis of a cytotoxicity test. A histopathological anatomy test showed that the collagen–chitosan–thymosin β4 hydrogels could stimulate angiogenesis and epicardial Heart cell migration, as demonstrated by the evaluation of the number of blood vessels and the infiltration extent of myofibroblasts
K Ludwig - One of the best experts on this subject based on the ideXlab platform.
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acute lower gastrointestinal hemorrhage minimally invasive management with microcatheter embolization
Journal of Vascular and Interventional Radiology, 2008Co-Authors: R Kickuth, Henning Rattunde, Jurgen Gschossmann, Daniel Inderbitzin, K Ludwig, Jiirgen TrillerAbstract:Purpose To evaluate the efficacy of superselective embolization therapy in the management of acute lower gastrointestinal (LGI) hemorrhage, including any bleeding distal to the ligament of Treitz. Materials and Methods Between June and August 2007, 20 patients with acute LGI bleeding underwent superselective transcatheter arterial embolization (TAE) at the authors' institution. The bleeding had different causes. All patients were treated with use of microcatheters. The following embolic agents were used: microcoils ( n = 16), polyvinyl alcohol (PVA) particles ( n = 2), and a combination of microcoils and PVA particles ( n = 2). Outcome measures included technical success (complete cessation of bleeding as documented at completion angiography), clinical success (resolution of signs or symptoms of LGI bleeding within 30 days after TAE), and the rate of major and minor complications. Results The identified bleeding sources were as follows: jejunal branch, branch of middle colic artery, branch of ileocolic artery, ileal branch, branch of left colic artery, branch of sigmoid artery, branch of the superior rectal artery, and branch of the middle rectal artery. Technical success with effective control of active bleeeding was achieved in all patients (100%). Clinical success attributed to TAE was documented in 18 of the 20 patients (90%). Major complications included death due to pulmonary embolism, Heart Infarction, and multiorgan failure in the 3rd week after TAE; a procedure-related colonic Infarction occurred in one patient. A minor complication occurred in one patient who developed a groin hematoma. Conclusions Superselective embolization may be used for effective, minimally invasive control of acute LGI bleeding.
