The Experts below are selected from a list of 138 Experts worldwide ranked by ideXlab platform
Mehdi Razavi - One of the best experts on this subject based on the ideXlab platform.
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Author Correction: Synchronized Biventricular Heart Pacing in a Closed-chest Porcine Model based on Wirelessly Powered Leadless Pacemakers.
Scientific reports, 2020Co-Authors: Hongming Lyu, Mathews John, David Burkland, Brian Greet, Aydin Babakhani, Allison Post, Mehdi RazaviAbstract:Author(s): Lyu, Hongming; John, Mathews; Burkland, David; Greet, Brian; Post, Allison; Babakhani, Aydin; Razavi, Mehdi | Abstract: An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Synchronized Biventricular Heart Pacing in a Closed-chest Porcine Model based on Wirelessly Powered Leadless Pacemakers.
Scientific reports, 2020Co-Authors: Hongming Lyu, Mathews John, David Burkland, Brian Greet, Aydin Babakhani, Allison Post, Mehdi RazaviAbstract:About 30% of patients with impaired cardiac function have ventricular dyssynchrony and seek cardiac resynchronization therapy (CRT). In this study, we demonstrate synchronized biventricular (BiV) Pacing in a leadless fashion by implementing miniaturized and wirelessly powered pacemakers. With their flexible form factors, two pacemakers were implanted epicardially on the right and left ventricles of a porcine model and were inductively powered at 13.56 MHz and 40.68 MHz industrial, scientific, and medical (ISM) bands, respectively. The power consumption of these pacemakers is reduced to µW-level by a novel integrated circuit design, which considerably extends the maximum operating distance. Leadless BiV Pacing is demonstrated for the first time in both open-chest and closed-chest porcine settings. The clinical outcomes associated with different interventricular delays are verified through electrophysiologic and hemodynamic responses. The closed-chest Pacing only requires the external source power of 0.3 W and 0.8 W at 13.56 MHz and 40.68 MHz, respectively, which leads to specific absorption rates (SARs) 2-3 orders of magnitude lower than the safety regulation limit. This work serves as a basis for future wirelessly powered leadless pacemakers that address various cardiac resynchronization challenges.
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EMBC - A Multi-site Heart Pacing Study Using Wirelessly Powered Leadless Pacemakers
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Inte, 2018Co-Authors: Hongming Lyu, Mathews John, David Burkland, Brian Greet, Luiz C. Sampaio, Doris A. Taylor, Mehdi Razavi, Aydin BabakhaniAbstract:In this work, we report an energy-efficient switched capacitor based millimeter-scale pacemaker (5 mm ×7.5 mm) and a multi-receiver wireless energy transfer system operating at around 200 MHz, and use them in a proof-of-concept multi-site Heart Pacing study. Two pacemakers were placed on two beating Langendorff rodent Heart models separately. By utilizing a single transmitter positioned 20-30 cm away, both Langendorff Hearts captured the stimuli simultaneously and were electromechanically coupled. This study provides an insight for future energy-efficient and distributed cardiac pacemakers that can offer cardiac resynchronization therapies.
Hongming Lyu - One of the best experts on this subject based on the ideXlab platform.
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Author Correction: Synchronized Biventricular Heart Pacing in a Closed-chest Porcine Model based on Wirelessly Powered Leadless Pacemakers.
Scientific reports, 2020Co-Authors: Hongming Lyu, Mathews John, David Burkland, Brian Greet, Aydin Babakhani, Allison Post, Mehdi RazaviAbstract:Author(s): Lyu, Hongming; John, Mathews; Burkland, David; Greet, Brian; Post, Allison; Babakhani, Aydin; Razavi, Mehdi | Abstract: An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Synchronized Biventricular Heart Pacing in a Closed-chest Porcine Model based on Wirelessly Powered Leadless Pacemakers.
Scientific reports, 2020Co-Authors: Hongming Lyu, Mathews John, David Burkland, Brian Greet, Aydin Babakhani, Allison Post, Mehdi RazaviAbstract:About 30% of patients with impaired cardiac function have ventricular dyssynchrony and seek cardiac resynchronization therapy (CRT). In this study, we demonstrate synchronized biventricular (BiV) Pacing in a leadless fashion by implementing miniaturized and wirelessly powered pacemakers. With their flexible form factors, two pacemakers were implanted epicardially on the right and left ventricles of a porcine model and were inductively powered at 13.56 MHz and 40.68 MHz industrial, scientific, and medical (ISM) bands, respectively. The power consumption of these pacemakers is reduced to µW-level by a novel integrated circuit design, which considerably extends the maximum operating distance. Leadless BiV Pacing is demonstrated for the first time in both open-chest and closed-chest porcine settings. The clinical outcomes associated with different interventricular delays are verified through electrophysiologic and hemodynamic responses. The closed-chest Pacing only requires the external source power of 0.3 W and 0.8 W at 13.56 MHz and 40.68 MHz, respectively, which leads to specific absorption rates (SARs) 2-3 orders of magnitude lower than the safety regulation limit. This work serves as a basis for future wirelessly powered leadless pacemakers that address various cardiac resynchronization challenges.
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EMBC - A Multi-site Heart Pacing Study Using Wirelessly Powered Leadless Pacemakers
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Inte, 2018Co-Authors: Hongming Lyu, Mathews John, David Burkland, Brian Greet, Luiz C. Sampaio, Doris A. Taylor, Mehdi Razavi, Aydin BabakhaniAbstract:In this work, we report an energy-efficient switched capacitor based millimeter-scale pacemaker (5 mm ×7.5 mm) and a multi-receiver wireless energy transfer system operating at around 200 MHz, and use them in a proof-of-concept multi-site Heart Pacing study. Two pacemakers were placed on two beating Langendorff rodent Heart models separately. By utilizing a single transmitter positioned 20-30 cm away, both Langendorff Hearts captured the stimuli simultaneously and were electromechanically coupled. This study provides an insight for future energy-efficient and distributed cardiac pacemakers that can offer cardiac resynchronization therapies.
David Burkland - One of the best experts on this subject based on the ideXlab platform.
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Author Correction: Synchronized Biventricular Heart Pacing in a Closed-chest Porcine Model based on Wirelessly Powered Leadless Pacemakers.
Scientific reports, 2020Co-Authors: Hongming Lyu, Mathews John, David Burkland, Brian Greet, Aydin Babakhani, Allison Post, Mehdi RazaviAbstract:Author(s): Lyu, Hongming; John, Mathews; Burkland, David; Greet, Brian; Post, Allison; Babakhani, Aydin; Razavi, Mehdi | Abstract: An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Synchronized Biventricular Heart Pacing in a Closed-chest Porcine Model based on Wirelessly Powered Leadless Pacemakers.
Scientific reports, 2020Co-Authors: Hongming Lyu, Mathews John, David Burkland, Brian Greet, Aydin Babakhani, Allison Post, Mehdi RazaviAbstract:About 30% of patients with impaired cardiac function have ventricular dyssynchrony and seek cardiac resynchronization therapy (CRT). In this study, we demonstrate synchronized biventricular (BiV) Pacing in a leadless fashion by implementing miniaturized and wirelessly powered pacemakers. With their flexible form factors, two pacemakers were implanted epicardially on the right and left ventricles of a porcine model and were inductively powered at 13.56 MHz and 40.68 MHz industrial, scientific, and medical (ISM) bands, respectively. The power consumption of these pacemakers is reduced to µW-level by a novel integrated circuit design, which considerably extends the maximum operating distance. Leadless BiV Pacing is demonstrated for the first time in both open-chest and closed-chest porcine settings. The clinical outcomes associated with different interventricular delays are verified through electrophysiologic and hemodynamic responses. The closed-chest Pacing only requires the external source power of 0.3 W and 0.8 W at 13.56 MHz and 40.68 MHz, respectively, which leads to specific absorption rates (SARs) 2-3 orders of magnitude lower than the safety regulation limit. This work serves as a basis for future wirelessly powered leadless pacemakers that address various cardiac resynchronization challenges.
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EMBC - A Multi-site Heart Pacing Study Using Wirelessly Powered Leadless Pacemakers
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Inte, 2018Co-Authors: Hongming Lyu, Mathews John, David Burkland, Brian Greet, Luiz C. Sampaio, Doris A. Taylor, Mehdi Razavi, Aydin BabakhaniAbstract:In this work, we report an energy-efficient switched capacitor based millimeter-scale pacemaker (5 mm ×7.5 mm) and a multi-receiver wireless energy transfer system operating at around 200 MHz, and use them in a proof-of-concept multi-site Heart Pacing study. Two pacemakers were placed on two beating Langendorff rodent Heart models separately. By utilizing a single transmitter positioned 20-30 cm away, both Langendorff Hearts captured the stimuli simultaneously and were electromechanically coupled. This study provides an insight for future energy-efficient and distributed cardiac pacemakers that can offer cardiac resynchronization therapies.
Brian Greet - One of the best experts on this subject based on the ideXlab platform.
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Author Correction: Synchronized Biventricular Heart Pacing in a Closed-chest Porcine Model based on Wirelessly Powered Leadless Pacemakers.
Scientific reports, 2020Co-Authors: Hongming Lyu, Mathews John, David Burkland, Brian Greet, Aydin Babakhani, Allison Post, Mehdi RazaviAbstract:Author(s): Lyu, Hongming; John, Mathews; Burkland, David; Greet, Brian; Post, Allison; Babakhani, Aydin; Razavi, Mehdi | Abstract: An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Synchronized Biventricular Heart Pacing in a Closed-chest Porcine Model based on Wirelessly Powered Leadless Pacemakers.
Scientific reports, 2020Co-Authors: Hongming Lyu, Mathews John, David Burkland, Brian Greet, Aydin Babakhani, Allison Post, Mehdi RazaviAbstract:About 30% of patients with impaired cardiac function have ventricular dyssynchrony and seek cardiac resynchronization therapy (CRT). In this study, we demonstrate synchronized biventricular (BiV) Pacing in a leadless fashion by implementing miniaturized and wirelessly powered pacemakers. With their flexible form factors, two pacemakers were implanted epicardially on the right and left ventricles of a porcine model and were inductively powered at 13.56 MHz and 40.68 MHz industrial, scientific, and medical (ISM) bands, respectively. The power consumption of these pacemakers is reduced to µW-level by a novel integrated circuit design, which considerably extends the maximum operating distance. Leadless BiV Pacing is demonstrated for the first time in both open-chest and closed-chest porcine settings. The clinical outcomes associated with different interventricular delays are verified through electrophysiologic and hemodynamic responses. The closed-chest Pacing only requires the external source power of 0.3 W and 0.8 W at 13.56 MHz and 40.68 MHz, respectively, which leads to specific absorption rates (SARs) 2-3 orders of magnitude lower than the safety regulation limit. This work serves as a basis for future wirelessly powered leadless pacemakers that address various cardiac resynchronization challenges.
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EMBC - A Multi-site Heart Pacing Study Using Wirelessly Powered Leadless Pacemakers
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Inte, 2018Co-Authors: Hongming Lyu, Mathews John, David Burkland, Brian Greet, Luiz C. Sampaio, Doris A. Taylor, Mehdi Razavi, Aydin BabakhaniAbstract:In this work, we report an energy-efficient switched capacitor based millimeter-scale pacemaker (5 mm ×7.5 mm) and a multi-receiver wireless energy transfer system operating at around 200 MHz, and use them in a proof-of-concept multi-site Heart Pacing study. Two pacemakers were placed on two beating Langendorff rodent Heart models separately. By utilizing a single transmitter positioned 20-30 cm away, both Langendorff Hearts captured the stimuli simultaneously and were electromechanically coupled. This study provides an insight for future energy-efficient and distributed cardiac pacemakers that can offer cardiac resynchronization therapies.
Mathews John - One of the best experts on this subject based on the ideXlab platform.
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Author Correction: Synchronized Biventricular Heart Pacing in a Closed-chest Porcine Model based on Wirelessly Powered Leadless Pacemakers.
Scientific reports, 2020Co-Authors: Hongming Lyu, Mathews John, David Burkland, Brian Greet, Aydin Babakhani, Allison Post, Mehdi RazaviAbstract:Author(s): Lyu, Hongming; John, Mathews; Burkland, David; Greet, Brian; Post, Allison; Babakhani, Aydin; Razavi, Mehdi | Abstract: An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Synchronized Biventricular Heart Pacing in a Closed-chest Porcine Model based on Wirelessly Powered Leadless Pacemakers.
Scientific reports, 2020Co-Authors: Hongming Lyu, Mathews John, David Burkland, Brian Greet, Aydin Babakhani, Allison Post, Mehdi RazaviAbstract:About 30% of patients with impaired cardiac function have ventricular dyssynchrony and seek cardiac resynchronization therapy (CRT). In this study, we demonstrate synchronized biventricular (BiV) Pacing in a leadless fashion by implementing miniaturized and wirelessly powered pacemakers. With their flexible form factors, two pacemakers were implanted epicardially on the right and left ventricles of a porcine model and were inductively powered at 13.56 MHz and 40.68 MHz industrial, scientific, and medical (ISM) bands, respectively. The power consumption of these pacemakers is reduced to µW-level by a novel integrated circuit design, which considerably extends the maximum operating distance. Leadless BiV Pacing is demonstrated for the first time in both open-chest and closed-chest porcine settings. The clinical outcomes associated with different interventricular delays are verified through electrophysiologic and hemodynamic responses. The closed-chest Pacing only requires the external source power of 0.3 W and 0.8 W at 13.56 MHz and 40.68 MHz, respectively, which leads to specific absorption rates (SARs) 2-3 orders of magnitude lower than the safety regulation limit. This work serves as a basis for future wirelessly powered leadless pacemakers that address various cardiac resynchronization challenges.
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EMBC - A Multi-site Heart Pacing Study Using Wirelessly Powered Leadless Pacemakers
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Inte, 2018Co-Authors: Hongming Lyu, Mathews John, David Burkland, Brian Greet, Luiz C. Sampaio, Doris A. Taylor, Mehdi Razavi, Aydin BabakhaniAbstract:In this work, we report an energy-efficient switched capacitor based millimeter-scale pacemaker (5 mm ×7.5 mm) and a multi-receiver wireless energy transfer system operating at around 200 MHz, and use them in a proof-of-concept multi-site Heart Pacing study. Two pacemakers were placed on two beating Langendorff rodent Heart models separately. By utilizing a single transmitter positioned 20-30 cm away, both Langendorff Hearts captured the stimuli simultaneously and were electromechanically coupled. This study provides an insight for future energy-efficient and distributed cardiac pacemakers that can offer cardiac resynchronization therapies.
