The Experts below are selected from a list of 1239 Experts worldwide ranked by ideXlab platform
El Hind - One of the best experts on this subject based on the ideXlab platform.
-
Primitive Heart Undifferenciated Sarcoma: A case Report and Literature Review Primitive Heart Undifferenciated Sarcoma: A case Report and Literature Review
2020Co-Authors: El Hind, El Yacoubi, Ouafki Inrhaouen Mrabti Errihani I , H , H , H HAbstract:Abstract The primary malignant cardiac tumors are extremely rare, they represent 25% of all primitive cardiac tumors. We report a case of a man aged 45 years with a tumor of the left atrium, discovered by a dyspnea, hemoptysis and faintness, chest X-ray showed a cardiomegaly and pulmonary parenchymal overload. The echocardiography found a mass in the left atrium obstructing the mitral orifice at each diastole. A complete surgical resection was performed and pathological examination found an undifferentiated Sarcoma, the patient was lost from view for 13 months. The reappearance of dyspnea related to local recurrence without metastasis has required a reoperation, immediate evolution was favorable. By the realisation of this observation, a literature review of the primary Heart Sarcoma was performed
Ouafki Inrhaouen Mrabti Errihani I , H , H , H H - One of the best experts on this subject based on the ideXlab platform.
-
Primitive Heart Undifferenciated Sarcoma: A case Report and Literature Review Primitive Heart Undifferenciated Sarcoma: A case Report and Literature Review
2020Co-Authors: El Hind, El Yacoubi, Ouafki Inrhaouen Mrabti Errihani I , H , H , H HAbstract:Abstract The primary malignant cardiac tumors are extremely rare, they represent 25% of all primitive cardiac tumors. We report a case of a man aged 45 years with a tumor of the left atrium, discovered by a dyspnea, hemoptysis and faintness, chest X-ray showed a cardiomegaly and pulmonary parenchymal overload. The echocardiography found a mass in the left atrium obstructing the mitral orifice at each diastole. A complete surgical resection was performed and pathological examination found an undifferentiated Sarcoma, the patient was lost from view for 13 months. The reappearance of dyspnea related to local recurrence without metastasis has required a reoperation, immediate evolution was favorable. By the realisation of this observation, a literature review of the primary Heart Sarcoma was performed
Ortega-uribe, Leec Fabían David - One of the best experts on this subject based on the ideXlab platform.
-
Sarcoma cardíaco metastático a miembros inferiores
'Universidad de Boyaca', 2020Co-Authors: Picón-jaimes, Yelson Alejandro, Orozco-chinome, Javier E, Ortega-uribe, Leec Fabían DavidAbstract:Introduction. Neoplasms of the Heart are infrequent pathologies with incidence rates in autopsy reports less than 0.02%. 75 % of these tumors are benign and only the remaining 25 % are considered cancerous. Although they occur in both sexes, the male to female ratio is 2.5: 1 respectively. Case report. We report the case of a 41-year-old patient who was diagnosed with a primary Heart Sarcoma, in the left atrium, with immunohistochemistry compatible with undifferentiated Sarcoma with metastases to the lower limbs, who debuted with impairment of functional class and loss of involuntary weight which led him to consult the doctor. Discussion. Undifferentiated Sarcomas constitute a rare pathology in the medical literature, finding only a few cases reports that share data, such as the location of the lesion and the clinical symptoms of the patients. However, this case reveals a strange case of metastasis to lower limbs, which was considered, after ruling out the presence of a patent foramen ovale or lung lesions that suggested a different tumor migration sequence. Conclusions. This is a complex pathology with a poor long-term prognosis that requires more research and multifactorial treatment with multidisciplinary teams to improve the quality of life of patientsIntroducción. Las neoplasias de corazón son patologías infrecuentes con tasas de incidencias en reportes de autopsias menores al 0.02 %. El 75 % de esos tumores son de comportamiento benigno y solo el 25 % restante se considera cáncer. Aunque se presentan en ambos sexos, la relación hombres mujeres es de 2.5:1 respectivamente. Presentación del caso. Reportamos el caso de un paciente de 41 años a quien se diagnosticó con un Sarcoma primario de corazón, en atrio izquierdo, con inmunohistoquímica compatible con Sarcoma indiferenciado con metástasis a miembros inferiores, que debutó con deterioro de la clase funcional y pérdida de peso involuntaria, lo cual lo llevó a consultar al médico. Discusión. Los Sarcomas indiferenciados constituyen una patología poco frecuente en la literatura médica, encontrando solo unos pocos reportes de casos que comparten datos relacionados con el sitio de localización de la lesión y los síntomas clínicos de los pacientes. Sin embargo, aquí se pone de manifiesto un extraño caso de metástasis a miembros inferiores, el cual fue considerado luego de descartar la presencia de un foramen oval permeable o lesiones pulmonares que hicieran pensar en una secuencia de migración tumoral diferente. Conclusiones. Se trata de una patología compleja con pobre pronóstico a largo plazo, la cual requiere mayor investigación y tratamiento multifactorial con equipos multidisciplinarios para mejorar la calidad de vida de los pacientes
-
Sarcoma cardíaco metastático dos membros inferiores
'Universidad de Boyaca', 2020Co-Authors: Picón-jaimes, Yelson Alejandro, Orozco-chinome, Javier E, Ortega-uribe, Leec Fabían DavidAbstract:Introduction. Neoplasms of the Heart are infrequent pathologies with incidence rates in autopsy reports less than 0.02%. 75 % of these tumors are benign and only the remaining 25 % are considered cancerous. Although they occur in both sexes, the male to female ratio is 2.5: 1 respectively. Case report. We report the case of a 41-year-old patient who was diagnosed with a primary Heart Sarcoma, in the left atrium, with immunohistochemistry compatible with undifferentiated Sarcoma with metastases to the lower limbs, who debuted with impairment of functional class and loss of involuntary weight which led him to consult the doctor. Discussion. Undifferentiated Sarcomas constitute a rare pathology in the medical literature, finding only a few cases reports that share data, such as the location of the lesion and the clinical symptoms of the patients. However, this case reveals a strange case of metastasis to lower limbs, which was considered, after ruling out the presence of a patent foramen ovale or lung lesions that suggested a different tumor migration sequence. Conclusions. This is a complex pathology with a poor long-term prognosis that requires more research and multifactorial treatment with multidisciplinary teams to improve the quality of life of patientsIntroducción. Las neoplasias de corazón son patologías infrecuentes con tasas de incidencias en reportes de autopsias menores al 0.02 %. El 75 % de esos tumores son de comportamiento benigno y solo el 25 % restante se considera cáncer. Aunque se presentan en ambos sexos, la relación hombres mujeres es de 2.5:1 respectivamente. Presentación del caso. Reportamos el caso de un paciente de 41 años a quien se diagnosticó con un Sarcoma primario de corazón, en atrio izquierdo, con inmunohistoquímica compatible con Sarcoma indiferenciado con metástasis a miembros inferiores, que debutó con deterioro de la clase funcional y pérdida de peso involuntaria, lo cual lo llevó a consultar al médico. Discusión. Los Sarcomas indiferenciados constituyen una patología poco frecuente en la literatura médica, encontrando solo unos pocos reportes de casos que comparten datos relacionados con el sitio de localización de la lesión y los síntomas clínicos de los pacientes. Sin embargo, aquí se pone de manifiesto un extraño caso de metástasis a miembros inferiores, el cual fue considerado luego de descartar la presencia de un foramen oval permeable o lesiones pulmonares que hicieran pensar en una secuencia de migración tumoral diferente. Conclusiones. Se trata de una patología compleja con pobre pronóstico a largo plazo, la cual requiere mayor investigación y tratamiento multifactorial con equipos multidisciplinarios para mejorar la calidad de vida de los pacientes.Introdução. As neoplasias do coração são patologias pouco frequentes, com taxas de incidência em relatórios de autópsia inferiores a 0,02%. 75% desses tumores são benignos e apenas 25% restantes são considerados câncer. Embora ocorram em ambos os sexos, a proporção entre homens e mulheres é de 2,5: 1 respectivamente. Apresentação do caso. Relatamos o caso de um paciente de 41 anos de idade com diagnóstico de Sarcoma primário do coração, no átrio esquerdo, com imuno-histoquímica compatível com Sarcoma indiferenciado com metástase nos membros inferiores, que começou com deterioração da classe funcional e perda involuntária de peso, o que o levou a consultar o médico. Discussão. Os Sarcomas indiferenciados constituem uma patologia rara na literatura médica, encontrando apenas alguns relatos de casos que compartilham dados relacionados ao local da localização da lesão e aos sintomas clínicos dos pacientes. No entanto, aqui é revelado um caso estranho de metástase nos membros inferiores, que foi considerado após descartar a presença de forame oval permeável ou lesões pulmonares que sugerem uma sequência de migração tumoral diferente. Conclusões. É uma patologia complexa, com mau prognóstico a longo prazo, que requer mais investigação e tratamento multifatorial com equipes multidisciplinares para melhorar a qualidade de vida dos pacientes
Brian A Bruckner - One of the best experts on this subject based on the ideXlab platform.
-
improved outcomes with the evolution of a neoadjuvant chemotherapy approach to right Heart Sarcoma
The Annals of Thoracic Surgery, 2017Co-Authors: Walid Abu K Saleh, Basel Ramlawi, Oz M Shapira, Odeaa Al Jabbari, Vinod Ravi, Robert S Benjamin, Jean Bernard Durand, Monika Leja, Shanda H Blackmon, Brian A BrucknerAbstract:Background Right-side Heart Sarcomas tend to be bulky, infiltrative, and difficult to treat. We have previously examined our outcomes with right Heart Sarcomas. Surgical resection with R0 margins showed better survival than positive margins but in only one third of cases could R0 status be achieved. The hypothesis for this study was that preoperative neoadjuvant chemotherapy would shrink the tumor margins and allow an increase in R0 resection, and hence, better survival. Methods Review of our cardiac tumor database from 1990 to 2015 yielded 133 primary cardiac Sarcoma cases. Of these, we identified 44 patients with primary right-side Heart Sarcomas. Prospective database and retrospective data collection and clinical outcomes were evaluated for all 44 patients. Primary outcomes included 30-day mortality and morbidity and long-term survival. We used univariate and multivariate analyses to identify independent predictors of overall survival. Results There were 27 male and 17 female patients with a mean age of 41 ± 12.7 years (range, 15 to 67). Seventy-three percent of the patients (32 of 44) received neoadjuvant chemotherapy. The most common tumor histology was angioSarcoma in 30 of 44 (68%). Thirty-day mortality was 4.5%, and statistically similar between the two groups. The median survival of patients who had R0 resection was 53.5 months compared with 9.5 months for R1. Neoadjuvant chemotherapy led to a doubling of survival (20 versus 9.5 months). Conclusions Neoadjuvant chemotherapy followed by radical surgery is a safe and effective strategy in patients with primary right-side Heart Sarcoma. This multimodality treatment enhances resectability (R0 resection) that translates into improved patient survival.
El Yacoubi - One of the best experts on this subject based on the ideXlab platform.
-
Primitive Heart Undifferenciated Sarcoma: A case Report and Literature Review Primitive Heart Undifferenciated Sarcoma: A case Report and Literature Review
2020Co-Authors: El Hind, El Yacoubi, Ouafki Inrhaouen Mrabti Errihani I , H , H , H HAbstract:Abstract The primary malignant cardiac tumors are extremely rare, they represent 25% of all primitive cardiac tumors. We report a case of a man aged 45 years with a tumor of the left atrium, discovered by a dyspnea, hemoptysis and faintness, chest X-ray showed a cardiomegaly and pulmonary parenchymal overload. The echocardiography found a mass in the left atrium obstructing the mitral orifice at each diastole. A complete surgical resection was performed and pathological examination found an undifferentiated Sarcoma, the patient was lost from view for 13 months. The reappearance of dyspnea related to local recurrence without metastasis has required a reoperation, immediate evolution was favorable. By the realisation of this observation, a literature review of the primary Heart Sarcoma was performed
