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Alejandro Alagón - One of the best experts on this subject based on the ideXlab platform.
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HelodermaTINE, A KALLIKREIN-LIKE, HYPOTENSIVE ENZYME FROM THE VENOM OF Heloderma HORRIDUM HORRIDUM (MEXICAN BEADED LIZARD)
2013Co-Authors: Alejandro Alagón, Lourival D Possani, John Smart, Wolf-dieter SchleuningAbstract:The Mexican beaded lizard (Heloderma horridum horridum) is one of the two members of venomous lizards of the family Helodermatidae (suborder, sauria) that inhabit the arid regions of the southwestern United States and the Pacific coast of Mexico. The Heloderma venom is less well characterized than many snake venoms. A neurotoxin (1), a hyaluronidase (2), peptides related to the vasoactive intestinal peptide-secretin family (3, 4), and two arginine esterases (M,. 22,000 and 63,000) have been described. Mebs (5) has seen a kinin-generating (or kallikrein-like) activity in the venom of the family member Gila monster (Heloderma suspectum), but no purification to homogeneity or detailed characterization of this activity was achieved. In the following report we describe a protein purification scheme that yields in two steps the electrophoretically homogeneous arginine esterase (M, 63,000) from lyophilized H. h. horridum venom. A detailed examination of its catalytic activity revealed properties closely related to kallikrei
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A new affinity adsorbent for the purification of phospholipases A1 and A2 from animal venoms.
Toxicon, 2002Co-Authors: Javier Vargas-villarreal, J.j. Martin-polo, Enrique Reynaud, Alejandro AlagónAbstract:Abstract Dimethyl- dl -2,3-distearoyloxypropyl-2′-hydroxy-ethylammonium (Rosenthal's inhibitor) was coupled to carboxyhexyl-Sepharose 4B, through carbodiimide chemistry. Phospholipase A 2 from Heloderma horridum horridum and Crotalus adamanteus bind to the immobilized ligand in the presence of Ca 2+ and can be easily eluted under acidic conditions or in the presence of a chelating agent, respectively. This affinity media proved to be effective also in the purification of a Ca 2+ -independent phospholipase A 1 from vespid venom.
Tianbao Chen - One of the best experts on this subject based on the ideXlab platform.
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Helokinestatin-7 peptides from the venoms of Heloderma lizards
Peptides, 2012Co-Authors: Hui Wang, Tianbao Chen, Lei Wang, Mei Zhou, Gemma Lowe, Yingqi Zhang, Christopher ShawAbstract:Abstract Helokinestatins 1–6 constitute a family of bradykinin antagonist peptides originally isolated from the venoms of the Gila Monster, Heloderma suspectum and the Mexican beaded lizard, Heloderma horridum. Here we report the identification, isolation and preliminary pharmacological characterization of two novel tridecapeptides, named helokinestatin-7S (FDDDSTELILEPR – 1550 Da) and helokinestatin-7H (FDDDSRKLILEPR – 1604 Da), whose primary structures were predicted from cDNAs cloned from venom libraries of respective Heloderma lizards. Computed molecular masses of putative helokinestatin-7 peptides were used as tools to locate these peptides in archived LC/MS fractions from respective venoms and sequences were confirmed by MS/MS fragmentation. A synthetic replicate of helokinestatin-7H was found to antagonize the relaxation effect of bradykinin on rat arterial smooth muscle but to have no measurable effects alone. In contrast, synthetic helokinestatin-7S was found to directly contract this preparation. Studies on related natural peptides with subtle differences in primary structure can provide the tools for structure/activity studies in pharmacological investigations directed toward unraveling the molecular basis of venom toxicity and for the evaluation of potential therapeutic leads.
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the natriuretic peptide helokinestatin precursor from mexican beaded lizard Heloderma horridum venom amino acid sequence deduced from cloned cdna and identification of two novel encoded helokinestatins
Peptides, 2011Co-Authors: Mu Yang, Tianbao Chen, Lei Wang, Mei Zhou, Anwei Ding, C. ShawAbstract:Abstract Natriuretic peptides are common components of reptile venoms and molecular cloning of their biosynthetic precursors has revealed that in snakes, they co-encode bradykinin-potentiating peptides and in venomous lizards, some co-encode bradykinin inhibitory peptides such as the helokinestatins. The common natriuretic peptide/helokinestatin precursor of the Gila Monster, Heloderma suspectum, encodes five helokinestatins of differing primary structures. Here we report the molecular cloning of a natriuretic peptide/helokinestatin precursor cDNA from a venom-derived cDNA library of the Mexican beaded lizard (Heloderma horridum). Deduction of the primary structure of the encoded precursor protein from this cloned cDNA template revealed that it consisted of 196 amino acid residues encoding a single natriuretic peptide and five helokinestatins. While the natriuretic peptide was of identical primary structure to its Gila Monster (H. suspectum) homolog, the encoded helokinestatins were not, with this region of the common precursor displaying some significant differences to its H. suspectum homolog. The helokinestatin-encoding region contained a single copy of helokinestatin-1, 2 copies of helokinestatin-3 and single copies of 2 novel peptides, (Phe)5-helokinestatin-2 (VPPAFVPLVPR) and helokinestatin-6 (GPPFNPPPFVDYEPR). All predicted peptides were found in reverse phase HPLC fractions of the same venom. Synthetic replicates of both novel helokinestatins were found to antagonize the relaxing effect of bradykinin on rat tail artery smooth muscle. Thus lizard venom continues to provide a source of novel biologically active peptides.
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The natriuretic peptide/helokinestatin precursor from Mexican beaded lizard (Heloderma horridum) venom: Amino acid sequence deduced from cloned cDNA and identification of two novel encoded helokinestatins☆
Peptides, 2011Co-Authors: Mu Yang, Tianbao Chen, Lei Wang, Mei Zhou, Anwei Ding, Christopher ShawAbstract:Abstract Natriuretic peptides are common components of reptile venoms and molecular cloning of their biosynthetic precursors has revealed that in snakes, they co-encode bradykinin-potentiating peptides and in venomous lizards, some co-encode bradykinin inhibitory peptides such as the helokinestatins. The common natriuretic peptide/helokinestatin precursor of the Gila Monster, Heloderma suspectum, encodes five helokinestatins of differing primary structures. Here we report the molecular cloning of a natriuretic peptide/helokinestatin precursor cDNA from a venom-derived cDNA library of the Mexican beaded lizard (Heloderma horridum). Deduction of the primary structure of the encoded precursor protein from this cloned cDNA template revealed that it consisted of 196 amino acid residues encoding a single natriuretic peptide and five helokinestatins. While the natriuretic peptide was of identical primary structure to its Gila Monster (H. suspectum) homolog, the encoded helokinestatins were not, with this region of the common precursor displaying some significant differences to its H. suspectum homolog. The helokinestatin-encoding region contained a single copy of helokinestatin-1, 2 copies of helokinestatin-3 and single copies of 2 novel peptides, (Phe)5-helokinestatin-2 (VPPAFVPLVPR) and helokinestatin-6 (GPPFNPPPFVDYEPR). All predicted peptides were found in reverse phase HPLC fractions of the same venom. Synthetic replicates of both novel helokinestatins were found to antagonize the relaxing effect of bradykinin on rat tail artery smooth muscle. Thus lizard venom continues to provide a source of novel biologically active peptides.
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helokinestatin a new bradykinin b2 receptor antagonist decapeptide from lizard venom
Peptides, 2008Co-Authors: Hang Fai Kwok, Tianbao Chen, Martin Orourke, Craig Ivanyi, David G Hirst, C. ShawAbstract:Abstract Synthetic bradykinin antagonist peptides/peptoids have been powerful tools for delineating the roles of kinins in both normal physiology and in pathological states. Here, we report the identification of a novel, naturally occurring bradykinin B2 receptor antagonist peptide, helokinestatin, isolated and structurally characterized from the venoms of Helodermatid lizards—the Gila monster (Heloderma suspectum) and the Mexican beaded lizard (Heloderma horridum). The primary structure of the peptide was established by a combination of microsequencing and mass spectroscopy as Gly-Pro-Pro-Tyr-Gln-Pro-Leu-Val-Pro-Arg (Mr 1122.62). A synthetic replicate of helokinestatin was found to inhibit bradykinin-induced vasorelaxation of phenylephrine pre-constricted rat tail artery smooth muscle, mediated by the B2 receptor sub-type, in a dose-dependent manner. Natural selection, that generates functional optimization of predatory reptile venom peptides, can potentially provide new insights for drug lead design or for normal physiological or pathophysiological processes.
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Isolation and cloning of exendin precursor cDNAs from single samples of venom from the Mexican beaded lizard (Heloderma horridum) and the Gila monster (Heloderma suspectum).
Toxicon, 2006Co-Authors: Tianbao Chen, Hang Fai Kwok, Craig Ivanyi, Christopher ShawAbstract:Reptile venoms are complex cocktails of bioactive molecules, including peptides. While the drug discovery potential of most species remains unrealized, many are endangered and afforded protection under international treaties. In this study, we describe how potential clinically important bioactive peptides and their corresponding mRNAs can be structurally characterized from single, small samples of reptile venom. The potential type-2 diabetes therapeutics, exendin-3 and exendin-4, from the Mexican beaded lizard (Heloderma horridum) and the Gila monster (Heloderma suspectum), respectively, have been characterized at both protein and nucleic acid levels to illustrate the efficacy of the technique and its contribution to biodiversity conservation.
Christopher Shaw - One of the best experts on this subject based on the ideXlab platform.
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Helokinestatin-7 peptides from the venoms of Heloderma lizards
Peptides, 2012Co-Authors: Hui Wang, Tianbao Chen, Lei Wang, Mei Zhou, Gemma Lowe, Yingqi Zhang, Christopher ShawAbstract:Abstract Helokinestatins 1–6 constitute a family of bradykinin antagonist peptides originally isolated from the venoms of the Gila Monster, Heloderma suspectum and the Mexican beaded lizard, Heloderma horridum. Here we report the identification, isolation and preliminary pharmacological characterization of two novel tridecapeptides, named helokinestatin-7S (FDDDSTELILEPR – 1550 Da) and helokinestatin-7H (FDDDSRKLILEPR – 1604 Da), whose primary structures were predicted from cDNAs cloned from venom libraries of respective Heloderma lizards. Computed molecular masses of putative helokinestatin-7 peptides were used as tools to locate these peptides in archived LC/MS fractions from respective venoms and sequences were confirmed by MS/MS fragmentation. A synthetic replicate of helokinestatin-7H was found to antagonize the relaxation effect of bradykinin on rat arterial smooth muscle but to have no measurable effects alone. In contrast, synthetic helokinestatin-7S was found to directly contract this preparation. Studies on related natural peptides with subtle differences in primary structure can provide the tools for structure/activity studies in pharmacological investigations directed toward unraveling the molecular basis of venom toxicity and for the evaluation of potential therapeutic leads.
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The natriuretic peptide/helokinestatin precursor from Mexican beaded lizard (Heloderma horridum) venom: Amino acid sequence deduced from cloned cDNA and identification of two novel encoded helokinestatins☆
Peptides, 2011Co-Authors: Mu Yang, Tianbao Chen, Lei Wang, Mei Zhou, Anwei Ding, Christopher ShawAbstract:Abstract Natriuretic peptides are common components of reptile venoms and molecular cloning of their biosynthetic precursors has revealed that in snakes, they co-encode bradykinin-potentiating peptides and in venomous lizards, some co-encode bradykinin inhibitory peptides such as the helokinestatins. The common natriuretic peptide/helokinestatin precursor of the Gila Monster, Heloderma suspectum, encodes five helokinestatins of differing primary structures. Here we report the molecular cloning of a natriuretic peptide/helokinestatin precursor cDNA from a venom-derived cDNA library of the Mexican beaded lizard (Heloderma horridum). Deduction of the primary structure of the encoded precursor protein from this cloned cDNA template revealed that it consisted of 196 amino acid residues encoding a single natriuretic peptide and five helokinestatins. While the natriuretic peptide was of identical primary structure to its Gila Monster (H. suspectum) homolog, the encoded helokinestatins were not, with this region of the common precursor displaying some significant differences to its H. suspectum homolog. The helokinestatin-encoding region contained a single copy of helokinestatin-1, 2 copies of helokinestatin-3 and single copies of 2 novel peptides, (Phe)5-helokinestatin-2 (VPPAFVPLVPR) and helokinestatin-6 (GPPFNPPPFVDYEPR). All predicted peptides were found in reverse phase HPLC fractions of the same venom. Synthetic replicates of both novel helokinestatins were found to antagonize the relaxing effect of bradykinin on rat tail artery smooth muscle. Thus lizard venom continues to provide a source of novel biologically active peptides.
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Isolation and cloning of exendin precursor cDNAs from single samples of venom from the Mexican beaded lizard (Heloderma horridum) and the Gila monster (Heloderma suspectum).
Toxicon, 2006Co-Authors: Tianbao Chen, Hang Fai Kwok, Craig Ivanyi, Christopher ShawAbstract:Reptile venoms are complex cocktails of bioactive molecules, including peptides. While the drug discovery potential of most species remains unrealized, many are endangered and afforded protection under international treaties. In this study, we describe how potential clinically important bioactive peptides and their corresponding mRNAs can be structurally characterized from single, small samples of reptile venom. The potential type-2 diabetes therapeutics, exendin-3 and exendin-4, from the Mexican beaded lizard (Heloderma horridum) and the Gila monster (Heloderma suspectum), respectively, have been characterized at both protein and nucleic acid levels to illustrate the efficacy of the technique and its contribution to biodiversity conservation.
Colin R. Mchenry - One of the best experts on this subject based on the ideXlab platform.
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Visual comparison of cranial and mandibular morphology between specimens.
2015Co-Authors: Matthew R. Mccurry, Tim S Jessop, Stephen Wroe, Phillip D Clausen, Michael Mahony, Michelle R. Quayle, Christopher W. Walmsley, Heather Richards, Colin R. MchenryAbstract:The morphology of each specimen is shown in dorsal and lateral view for both the cranium and mandible. Species are ordered by cranial PC1 values. Abbreviations: H.hor, Heloderma horridum; L.bor, Lanthanotus borneensis; V.aca, Varanus acanthurus; V.exa, Varanus exanthematicus; V.gou, Varanus gouldii; V.kom, Varanus komodoensis; V.pan h, Varanus panoptes horni; V.pan p, Varanus panoptes panoptes; V.pra, Varanus prasinus; V.sdi, Varanus salvadorii; V.slt, Varanus salvator; V.stor, Varanus storri; V.tri, Varanus tristis.
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VM Strain plots: Pull loading.
2015Co-Authors: Matthew R. Mccurry, Tim S Jessop, Stephen Wroe, Phillip D Clausen, Michael Mahony, Michelle R. Quayle, Christopher W. Walmsley, Heather Richards, Colin R. MchenryAbstract:Cool colours (blues) represent areas of low stain, hot colours (reds) represent areas of high strain and white areas represent areas where the upper strain threshold (200 μԐ) was exceeded. An arbitrary load of 30N was applied anteriorly through H beams connecting the four middle teeth. Abbreviations: H.hor, Heloderma horridum; L.bor, Lanthanotus borneensis; V.aca, Varanus acanthurus; V.exa, Varanus exanthematicus; V.gou, Varanus gouldii; V.kom, Varanus komodoensis; V.pan h, Varanus panoptes horni; V.pan p, Varanus panoptes panoptes; V.pra, Varanus prasinus; V.sdi, Varanus salvadorii; V.slt, Varanus salvator; V.stor, Varanus storri; V.tri, Varanus tristis.
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VM Strain plots: Shake loading.
2015Co-Authors: Matthew R. Mccurry, Tim S Jessop, Stephen Wroe, Phillip D Clausen, Michael Mahony, Michelle R. Quayle, Christopher W. Walmsley, Heather Richards, Colin R. MchenryAbstract:Cool colours (blues) represent areas of low stain, hot colours (reds) represent areas of high strain and white areas represent areas where the upper strain threshold (500 μԐ) was exceeded. An arbitrary load of 20N was applied laterally through H beams connecting the four middle teeth. Abbreviations: H.hor, Heloderma horridum; L.bor, Lanthanotus borneensis; V.aca, Varanus acanthurus; V.exa, Varanus exanthematicus; V.gou, Varanus gouldii; V.kom, Varanus komodoensis; V.pan h, Varanus panoptes horni; V.pan p, Varanus panoptes panoptes; V.pra, Varanus prasinus; V.sdi, Varanus salvadorii; V.slt, Varanus salvator; V.stor, Varanus storri; V.tri, Varanus tristis.
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VM Strain plots: Bite loading.
2015Co-Authors: Matthew R. Mccurry, Tim S Jessop, Stephen Wroe, Phillip D Clausen, Michael Mahony, Michelle R. Quayle, Christopher W. Walmsley, Heather Richards, Colin R. MchenryAbstract:Cool colours (blues) represent areas of low stain, hot colours (reds) represent areas of high strain and white areas represent areas where the upper strain threshold (1000 μԐ) was exceeded. Load was applied through muscle beams at a magnitude that standardised bite force at the teeth to 47.8 N (see S1 Table for muscle forces used for each model). Abbreviations: H.hor, Heloderma horridum; L.bor, Lanthanotus borneensis; V.aca, Varanus acanthurus; V.exa, Varanus exanthematicus; V.gou, Varanus gouldii; V.kom, Varanus komodoensis; V.pan h, Varanus panoptes horni; V.pan p, Varanus panoptes panoptes; V.pra, Varanus prasinus; V.sdi, Varanus salvadorii; V.slt, Varanus salvator; V.stor, Varanus storri; V.tri, Varanus tristis.
Manuel Antonio Rojas-pérez - One of the best experts on this subject based on the ideXlab platform.
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New report of Mexican scorpion Heloderma horridum (Reptilia: Helodermidae) in Durango State, Mexico
Revista Mexicana De Biodiversidad, 2009Co-Authors: Raúl Muñiz-martínez, Manuel Antonio Rojas-pérezAbstract:The Beaded Mexican Reptile is one of the 2 species recognized as venomous reptiles in the world. There are known 3 subspecies of Heloderma horridum, all show a very localized distribution, along the Pacifi c Coast. At the Southwestern part of Durango, this species was seen at the river Presidio. One specimen of Heloderma horridum, was observed and photographed, by a group of topography technical, who donated the pictures. By using taxonomic keys, the specimen was determined as Heloderma horridum. This species is registered in NOM-ECOL-059-2001, and is considered Amazing species, so the specimen was not collected. This is new registration, broads the geographical distribution of this taxon towards the southwestern of the Sierra Madre Occidental and its presence in Durango state, Mexico. Key word: distribution, Gila monster, reptiles. Entre las 725 especies de reptiles de Mexico (FloresVillela et al., 2004), en el grupo de las lagartijas, se encuentra el escorpion mexicano Heloderma horridum Wiegmann, 1829. Este grupo ha sido poco estudiado, sus poblaciones son escasas y se encuentran en la lista de especies amenazadas en la NOM-ECOL-059-2001 (SEMARNAT, 2002). Se desconoce el tamano real y distribucion de sus poblaciones; Aguilar (2005) indica aproximadamente 16 localidades de registro en Mexico, que se encuentran en vegetacion natural o poco perturbada. Por medio de fotografias a color se determino la especie a que corresponde el ejemplar y se calculo el tamano de la cola en proporcion al cuerpo, que es la principal caracteristica taxonomica para diferenciar entre H. suspetum y H. horridum; el tamano en la primera especie es notoriamente mayor. La revision de la descripcion de este taxon se baso en los trabajos de Bogert y Martin del Campo (1956) y Aguilar (2005), y utilizando las claves de Smith y Taylor (1945) y Bogert y Martin del Campo (1956) se confi rmo la determinacion del ejemplar. Durante un transecto realizado por un equipo de topografos encargados de supervisar el camino para la nueva carretera Durango-Mazatlan, el dia 10 de septiembre del 2007, al ver el ejemplar, lo denominaron ‘lagartija perlada’, y tomaron varias fotografias. El encargado de esa cuadrilla las trajo al Laboratorio de Fauna Silvestre del Centro Interdisciplinario de Investigacion para el Desarrollo Integral Regional, Unidad Durango, del Instituto Politecnico Nacional, en la ciudad de Durango, Mexico. Al revisar la bibliografia se encontro que esta especie no 872 Muniz-Martinez y Rojas-Perez.Registro nuevo de Heloderma en Mexico esta registrada para el estado de Durango. La localidad donde se observo, se encuentra sobre el rio Presidio, en el municipio de Pueblo Nuevo, Durango, y se situa a 52.9 km S, 111.15 km O de Durango, 1 059 m de altitud, a los 23° 32’ 37.968” N; 105° 45’ 32.904” O, muy cercana a Sinaloa. La informacion obtenida y la descripcion del ejemplar concuerda con la de los autores Aguilera (2005) y Bogert y Martin del Campo (1956) y se reconoce como un nuevo registro para el estado de Durango. Este hallazgo, confi rma la presencia de la especie en el estado, y amplia su distribucion hacia la parte suroeste de la sierra Madre Occidental. Aguilar (2005) describe H. horridum como sigue: Saurios grandes (400 mm de longitud), con cabeza y cuerpo grandes, cola corta, robustos. La punta de la cabeza es de color castano oscuro a negro, mientras que la parte superior, los lados y porcion ventral es castano claro; el cuerpo, la cola y las extremidades varian de castano claro a oscuro en la porcion posterior del cuerpo; sobre la porcion dorsal de las partes antes mencionadas, existe una serie de manchas grandes, mas o menos redondeadas, de color amarillo claro y hacia los lados del cuerpo; las extremidades posteriores y cola, forman bandas amarillas transversales; ventralmente, la coloracion es castano claro, con una serie de manchas irregulares amarillo claro; la cola es oscura y las bandas dorsales transversales claras, no constituyendo verdaderos anillos alrededor de ella. Al revisar el trabajo de Bogert y Martin del Campo (1956), la descripcion que dan para esta especie concuerda con el ejemplar observado; la subespecie a la que corresponde es H. horridum horridum que es la que tiene mayor distribucion en Mexico, a lo largo de la costa del oceano Pacifi co. En la Figura 1, donde se muestra el ejemplar, se observan las caracteristicas de la coloracion de la cola, como indican los autores antes mencionados. El ejemplar fotografi ado presenta coloracion negra con bandas amarillas; en la cola pueden verse 7 bandas; la longitud es casi la del cuerpo. En cuanto a su distribucion historica estimada, Aguilar (2005) menciona: Existen registros para esta especie en los estados de Colima, Chiapas, Estado de Mexico, Guerrero, Jalisco, Michoacan, Nayarit, Oaxaca y Sinaloa. Distribucion actual, con poblaciones aun presentes: Chiapas, Colima Estado de Mexico, Guerrero, Jalisco, Michoacan, Morelos, Nayarit, Sinaloa y Sonora. El habitat de esta especie es en areas no perturbadas. Posiblemente la distribucion actual es mucho menor que la historica, los registros que se han tenido de los ultimos 20 anos son para Colima, Jalisco y Estado de Mexico. Esta distribucion concuerda con Smith y Smith (1976) y Flores-Villela (1993), quienes indicando la presencia de la subespecie en el estado de Morelos, reiteran que se localiza en las regiones de tierras secas extra tropicales en Sonora, que comprenden las tierras bajas tropicales de la costa del Pacifi co, la cuenca del Balsas y la depresion central y sur de Chiapas, y las tierras altas extra tropicales que corresponden a la sierra Madre Occidental. En la Figura 2 se muestra la distribucion para H. horridum, de acuerdo Beck (2005). Figura 1. Heloderma horridum, vista lateral en el Rio Baluarte, Mpio. Pueblo Nuevo, Durango. Figura 2. Ubicacion del nuevo registro en Durango en relacion a la distribucion de Heloderma horridum y H. suspectum de acuerdo Beck (2005). Revista Mexicana de Biodiversidad 80: 871873, 2009 873 Existen muy pocos registros de esta especie que no es muy conocida y poco comun observarla; no obstante que por sus caracteristicas es facil reconocerla. En este caso, se observo en Durango, lo cual indica que aun faltan por realizarse estudios profundos acerca de la herpetofauna del estado, con el fi n de preservar su biodiversidad y aumentar el conocimiento sobre este grupo de reptiles. El mayor problema al que se enfrenta Heloderma es la actividad humana. Comunmente es temida por su veneno, pero debido a que su aspecto se considera atractivo se le busca como mascota o se recolecta con fi nes medicinales y afrodisiacos, todo lo cual hace que la especie tenga valor comercial, generando su trafi co ilegal (Aguilar, 2005). Se agradece al grupo de topografos que advirtieron la presencia de esta lagartija y nos proporcionaron las fotografias que permitieron determinar el ejemplar. Asimismo, agradecemos a los colegas del CIIDIR-IPNDurango que revisaron este escrito aportando acertadas observaciones.
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Registro nuevo del escorpión mexicano Heloderma horridum (Reptilia: Helodermidae) en Durango, México
Revista Mexicana de Biodiversidad, 2009Co-Authors: Raúl Muñiz-martínez, Manuel Antonio Rojas-pérezAbstract:The Beaded Mexican Reptile is one of the 2 species recognized as venomous reptiles in the world. There are known 3 subspecies of Heloderma horridum, all show a very localized distribution, along the Pacifi c Coast. At the Southwestern part of Durango, this species was seen at the river Presidio. One specimen of Heloderma horridum, was observed and photographed, by a group of topography technical, who donated the pictures. By using taxonomic keys, the specimen was determined as Heloderma horridum. This species is registered in NOM-ECOL-059-2001, and is considered Amazing species, so the specimen was not collected. This is new registration, broads the geographical distribution of this taxon towards the southwestern of the Sierra Madre Occidental and its presence in Durango state, Mexico. Key word: distribution, Gila monster, reptiles.
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Registro nuevo del escorpión mexicano Heloderma horridum (Reptilia: Helodermidae) en Durango, México New report of Mexican scorpion Heloderma horridum (Reptilia: Helodermidae) in Durango State, Mexico
Universidad Nacional Autónoma de México, 2009Co-Authors: Raúl Muñiz-martínez, Manuel Antonio Rojas-pérezAbstract:El escorpión mexicano Heloderma horridum es una de las 2 especies de lagartijas venenosas que se conocen en el mundo; hay 3 subespecies, todas en una distribución muy localizada, a lo largo de la costa del Pacífico. En la parte suroeste de Durango, en el río Presidio, un grupo de técnicos topógrafos observaron un ejemplar de Heloderma horridum y tomaron fotografías, las cuales aportaron al autor de esta nota, quien por medio de claves determinó la especie. Se trata de una especie que se considera amenazada dentro de la NOM-ECOL-059-2001, razón por la cual no se recolectó. Este registro amplía la distribución de la especie hacia el suroeste de la sierra Madre Occidental y confirma su presencia en el estado de Durango, México.The Beaded Mexican Reptile is one of the 2 species recognized as venomous reptiles in the world. There are known 3 subspecies of Heloderma horridum, all show a very localized distribution, along the Pacific Coast. At the Southwestern part of Durango, this species was seen at the river Presidio. One specimen of Heloderma horridum, was observed and photographed, by a group of topography technical, who donated the pictures. By using taxonomic keys, the specimen was determined as Heloderma horridum. This species is registered in NOM-ECOL-059-2001, and is considered Amazing species, so the specimen was not collected. This is new registration, broads the geographical distribution of this taxon towards the southwestern of the Sierra Madre Occidental and its presence in Durango state, Mexico