The Experts below are selected from a list of 156 Experts worldwide ranked by ideXlab platform
Louis D. Wadsworth - One of the best experts on this subject based on the ideXlab platform.
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An evaluation of Hemoglobin Determination using sodium lauryl sulfate.
American journal of clinical pathology, 1993Co-Authors: Aly Karsan, Ian A. Maclaren, Debbie Conn, Louis D. WadsworthAbstract:The standard reference method for Hemoglobin Determination for years has been the photometric quantitation of cyanmetHemoglobin. Other existing methods have not gained popularity in North America. In an attempt to eliminate hazardous cyanide waste, a method to determine the Hemoglobin concentration in whole blood using sodium lauryl sulfate has been devised and recently was released as a commercial reagent. The authors compare this new method with the cyanmetHemoglobin method using two hematology analyzers. Their results show that there is excellent correlation between the two methods (r2 = 0.996). In addition, other elements of the complete blood count also show good correlation. Thus, it was confirmed that the sodium lauryl sulfate method of estimating Hemoglobin concentration is an appropriate alternative to the cyanmetHemoglobin method and avoids the generation of toxic wastes.
Aly Karsan - One of the best experts on this subject based on the ideXlab platform.
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An evaluation of Hemoglobin Determination using sodium lauryl sulfate.
American journal of clinical pathology, 1993Co-Authors: Aly Karsan, Ian A. Maclaren, Debbie Conn, Louis D. WadsworthAbstract:The standard reference method for Hemoglobin Determination for years has been the photometric quantitation of cyanmetHemoglobin. Other existing methods have not gained popularity in North America. In an attempt to eliminate hazardous cyanide waste, a method to determine the Hemoglobin concentration in whole blood using sodium lauryl sulfate has been devised and recently was released as a commercial reagent. The authors compare this new method with the cyanmetHemoglobin method using two hematology analyzers. Their results show that there is excellent correlation between the two methods (r2 = 0.996). In addition, other elements of the complete blood count also show good correlation. Thus, it was confirmed that the sodium lauryl sulfate method of estimating Hemoglobin concentration is an appropriate alternative to the cyanmetHemoglobin method and avoids the generation of toxic wastes.
Allan S Detsky - One of the best experts on this subject based on the ideXlab platform.
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the relation of conjunctival pallor to the presence of anemia
Journal of General Internal Medicine, 1997Co-Authors: Tarang N Sheth, Niteesh K Choudhry, Matt Bowes, Allan S DetskyAbstract:To determine the value of conjunctival pallor in ruling in or ruling out the presence of severe anemia (Hemoglobin 90 g/L) and to determine the interobserver agreement in assessing this sign. Patients were prospectively assessed for pallor by at least one of three observers. All observations were made without information of the patient's Hemoglobin value or of another observer's assessment. Tertiary-care, university-affiliated teaching hospital. Three hundred and two medical and surgical inpatients. Likelihood ratios (LRs) calculated for conjunctival pallor present, borderline, and absent were as follows: pallor present, LR 4.49 (95% confidence interval [CI] 1.80, 10.99); pallor borderline, LR 1.80 (95% CI 1.18, 2.62); pallor absent, LR 0.61 (95% CI 0.44, 0.80). Kappa scores of interobserver agreement between paired observers were 0.75 and 0.54. The presence of conjunctival pallor, without other information suggesting anemia, is reason enough to perform a Hemoglobin Determination. The absence of conjunctival pallor is not likely to be of use in ruling out severe anemia. With well-defined criteria, interobserver agreement is good to very good.
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The Relation of Conjunctival Pallor to the Presence of Anemia
Journal of General Internal Medicine, 1997Co-Authors: Tarang N Sheth, Niteesh K Choudhry, Matt Bowes, Allan S DetskyAbstract:OBJECTIVE: To determine the value of conjunctival pallor in ruling in or ruling out the presence of severe anemia (Hemoglobin 90 g/L) and to determine the interobserver agreement in assessing this sign. DESIGN: Patients were prospectively assessed for pallor by at least one of three observers. All observations were made without information of the patient's Hemoglobin value or of another observer's assessment. SETTING: Tertiary-care, university-affiliated teaching hospital. PATIENTS: Three hundred and two medical and surgical inpatients. MEASUREMENTS AND MAIN RESULTS: Likelihood ratios (LRs) calculated for conjunctival pallor present, borderline, and absent were as follows: pallor present, LR 4.49 (95% confidence interval [CI] 1.80, 10.99); pallor borderline, LR 1.80 (95% CI 1.18, 2.62); pallor absent, LR 0.61 (95% CI 0.44, 0.80). Kappa scores of interobserver agreement between paired observers were 0.75 and 0.54. CONCLUSIONS: The presence of conjunctival pallor, without other information suggesting anemia, is reason enough to perform a Hemoglobin Determination. The absence of conjunctival pallor is not likely to be of use in ruling out severe anemia. With well-defined criteria, interobserver agreement is good to very good.
Ian A. Maclaren - One of the best experts on this subject based on the ideXlab platform.
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An evaluation of Hemoglobin Determination using sodium lauryl sulfate.
American journal of clinical pathology, 1993Co-Authors: Aly Karsan, Ian A. Maclaren, Debbie Conn, Louis D. WadsworthAbstract:The standard reference method for Hemoglobin Determination for years has been the photometric quantitation of cyanmetHemoglobin. Other existing methods have not gained popularity in North America. In an attempt to eliminate hazardous cyanide waste, a method to determine the Hemoglobin concentration in whole blood using sodium lauryl sulfate has been devised and recently was released as a commercial reagent. The authors compare this new method with the cyanmetHemoglobin method using two hematology analyzers. Their results show that there is excellent correlation between the two methods (r2 = 0.996). In addition, other elements of the complete blood count also show good correlation. Thus, it was confirmed that the sodium lauryl sulfate method of estimating Hemoglobin concentration is an appropriate alternative to the cyanmetHemoglobin method and avoids the generation of toxic wastes.
Debbie Conn - One of the best experts on this subject based on the ideXlab platform.
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An evaluation of Hemoglobin Determination using sodium lauryl sulfate.
American journal of clinical pathology, 1993Co-Authors: Aly Karsan, Ian A. Maclaren, Debbie Conn, Louis D. WadsworthAbstract:The standard reference method for Hemoglobin Determination for years has been the photometric quantitation of cyanmetHemoglobin. Other existing methods have not gained popularity in North America. In an attempt to eliminate hazardous cyanide waste, a method to determine the Hemoglobin concentration in whole blood using sodium lauryl sulfate has been devised and recently was released as a commercial reagent. The authors compare this new method with the cyanmetHemoglobin method using two hematology analyzers. Their results show that there is excellent correlation between the two methods (r2 = 0.996). In addition, other elements of the complete blood count also show good correlation. Thus, it was confirmed that the sodium lauryl sulfate method of estimating Hemoglobin concentration is an appropriate alternative to the cyanmetHemoglobin method and avoids the generation of toxic wastes.